CLINICAL OBSERVATION ON TREATMENT OF ALLERGIC BRONCHIAL ASTHMA WITH ACUPOINT APPLICATION THERAPY

In the present paper, the therapeutic effect of acupoint application of Chinese Materia Medica in the treatment of allergic asthma was observed. The results revealed that topical application of drug paste [mixture of powder of Mahuang (Herba Ephedrae), Xixin (Herba Asari), Baijiezi (Semen Sinapis Albae), etc.] at the acupuncture points could improve symptoms and signs of allergic asthma patients, with the total effective rate being 69.57% (16/23) for the short term effect, and 52.17%(12/23) for the long term effect. In medication (Aminophylline) group, of the 25 cases of allergic asthma, 16 (64.0%) were effective after 4 weeks of treatment, while 6 (24.0%) were still effective that was shown by 6 months’ follow up. The therapeutic effect of acupoint application group was significantly better than that of medication group in the long term effect. Results also showed that no obvious interrelation between the short term therapeutic effect and the duration or the severity of the disease. Results also display that acupoint application therapy is an effective, safe and handy method with fewer side effects for asthma.

Research on mechanism of Jin-Shui-Liu-Jun-Jian and Acupoint Application combined therapy for chronic bronchitis

Objective:To investigate the influencing mechanism of Jin-Shui-Liu-Jun-Jian and Acupoint Application combined therapy on hemorheology, inflammatory factors and pulmonary functions in patients with chronic bronchitis, thus to offer relevant help for clinical therapies on patients with chronic bronchitis. Methods:120 cases of patients with chronic bronchitis treated in our hospital were selected and randomly divided to be the therapeutic group and the control group, 60 cases each. Patients in control group were provided some basic treatments, such as spasmolysis, anti-inflammation, asthma relieving, oxygen inhalation and dissolve phlegm. For therapeutic group on this basis, Jin-Shui-Liu-Jun-Jian and Acupoint Application combined therapy was provided. Hemorheology, inflammatory factors and pulmonary functions in the two groups of patients were detected before and after treatment. Results:Differences of hemorheology indexes, inflammatory factors and pulmonary function relevant indexes between the two groups of patients with chronic bronchitis before treatment showed no statistical significance (P>0.05). Compared with prior treatment, hemorheology relevant indexes [whole blood high shear viscosity (WHV), whole blood low shear viscosity (WLV), packed cell volume (PCV), plasma viscosity (PV) and red cell assembling index (RCAI)], inflammatory factors [IL-8 (interleukin-8) and TNF-α(tumor necrosis factor-α)] were significantly decreased and pulmonary function relevant indexes [forced vital capacity (FVC), forced expiratory volume in one second (FEV1.0), peak expiratory flow (PEF), maximal voluntary ventilation (MVV) and expiratory flow rate when exhale vital capacity was 0.50], inflammatory factors (IL-4, IL-2) were significantly increased in the two groups of patients with chronic bronchitis after relevant treatments;The differences between the groups showed statistical significance (P<0.05). After combined therapy provided, pulmonary function relevant indexes (FVC, FEV1.0, PEF, MVV and V0.50) and inflammatory factors (IL-4, IL-2) in therapeutic group were significantly higher than control group after basic therapy. Hemorheology relevant indexes (WHV, WLV, PV, PCV and RCAI) and inflammatory factors (IL-8 and TNF-α) in therapeutic group were significantly lower than control group;Differences between the two groups showed statistical significance (P<0.05). Conclusions: Combination of Jin-Shui-Liu-Jun-Jian and Acupoint Application significantly improved the levels of hemorheology, inflammatory factors and pulmonary functions in patients with chronic bronchitis. It has a great important clinical significance on therapies for patients with chronic bronchitis.

Clinical Comparison and Analysis of Decoction of Traditional Chinese Medicine Combined with Ear Acupoint Application and Simple Artificial Tears in the Treatment of Dry Eye Syndrome

OBJECTIVE: To study the clinical comparison and analysis of decoction of Traditional Chinese Medicine(TCM) combined with ear acupoint application and simple artificial tears in the treatment of dry eye syndrome. METHODS:A total of 62 patients(124 eyes) with dry eye syndrome treated in the Department of Ophthalmology of The 4th People's Hospital of Shenyang from July 2017 to March 2018 were selected and equally divided into 2 groups according to the admission order. The observation group received the combination therapy of TCM decoction and ear acupoint application, while the control group was given the simple artificial tears. The symptom score after 2 weeks, 4 weeks, and 8 weeks as well as the indicators including break-up time(BUT), Schirmer I test(SIT) and fluorescein(FL) were recorded and compared between groups. RESULTS: The symptom scores had no difference before treatment(P > 0.05), and were better in the observation group than those in the control group after treatment(P < 0.05). At 2 weeks, 4 weeks, and 8 weeks after the treatment, the amelioration level of BUT, SIT, and FL indicators in the observation group was better than that of the control group(P < 0.05). CONCLUSION: Compared with the artificial tears treatment method, the TCM decoction combined with ear acupoint application can significantly ameliorate the tear film stability, tear secretion, and reduce ocular surface damage for dry eye patients.

Preventing Lower Extremity Deep Vein Thrombosis After Hip Fracture Surgery in Elderly Patients by Acupoint Application Combined with Pneumatic Compression Therapy

Objective:To investigate and analyze the long-term clinical effects of acupoint application combined with pneumatic compression therapy in the prevention of deep venous thrombosis after hip fracture surgery among the elderly.Methods:Sixty elderly patients who had undergone hip fracture surgery from February 2021 to February 2022 were selected as the research subjects.The patients were divided into two groups via drawing lots.Both the groups received nursing care,but the patients in the observation group were treated with TCM acupoint application combined with pneumatic compression therapy,whereas the control group received pneumatic compression therapy.The evaluation indicators included the patients’quality of life and complications.Results:The incidence of lower extremity deep vein thrombosis in the observation group was more than twice(0.3%),whereas the incidence of lower extremity complications in the control group was more than 6 times(20%).There was a significant difference between the two groups(p<0.05).Conclusion:Traditional Chinese medicine acupoint application combined with pneumatic compression therapy is beneficial for the prevention of postoperative lower extremity deep vein thrombosis among elderly patients.In addition,the patients’overall quality-of-life scores in both physiological and psychological aspects improved significantly,which carries significant clinical reference value.

OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPOINT APPLICATION OF FAR-INFRARED ASTHMA-RELIEVING PLASTER FOR ASTHMA

Objective To observe the clinical effect of acupoint application of Yuanhongwai Xiaochuankang Plaster （Far-infrared Asthma-relieving Plaster, FIRARP） for prevention and treatment of asthma. Methods Three hundred and sixty-six cases of bronchial asthma were randomly divided into treatment group （n = 185） and control group （n = 181 ）. Patients of treatment group were treated with FIRARP and those of control group treated with external application of traditional ＂Sonfu （Dog-days） moxibustion＂ （herbal-paste-cake separated moxibustion） and acupoints used were Dazhui（大椎 GV14）, Feishu（肺俞BL13）, Tiantu （天突 CV22）, etc. which were given to the patients. Forced expiratory volume in 1 second （FEV1） and peak expiratory flow （PEF） of the pulmonary function were determined and the changes of main symptoms and signs were observed before and after the treatment. Results The pulmonary functions were effectively improved, the symptoms were controlled, and the asthma attack was reduced in the two groups with no significant difference between the two groups （P 〉0.05）. Conclusion There is no significant difference between Yuanhongwai Xiaochuonkong Plaster and traditional ＂Sanfu moxibustion＂ on bronchial asthma. It may substitute for traditional ＂Sonfu moxibustion＂.

Observation of therapeutic effect of acupoint application on constipation

Objective To explore the efficacy and safety of acupoint application in treatment of constipation. Methods Sixty-two cases were randomly divided into 2 groups, named acupoint application group （32 cases） and Chinese herb group （30 cases）. In the acupoint application group, Chinese herbal plaster was applied on Tianshu （天枢 ST 25）, Gufnyuan （关元 CV 4） and Qihai （气海 CV 6）. In the Chinese herb group, Congrong Tongbian Koufuye （苁蓉通便口服液） was administered orally. The efficacy was observed after 7 days treatment. Results The total effective rate was 81.3% （26/32） in the acupoint application group and was 60.0% （18/30） in the Chinese herb group, indicating significant statistical difference in comparison （P〈0.05）. The significant difference presented in the time of the first defecation after treatment between two groups （P〈0.05）. The defecation promotion in the acupoint appli- cation group was superior to that in the Chinese herb group. The significant difference resulted in the comparison of clinical symptom integral before and after treatment in two groups （P〈0. 05）. The group comparison did not present significant difference. Conclusion Acupoint application of Chinese herbs has definite efficacy on constipation. It is convenient in operation, no pain and less toxic side effect and good in compliance.

子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型功能性消化不良临床观察

目的观察子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型功能性消化不良(FD)的临床疗效。方法将120例脾胃虚寒型FD患者按照随机数字表法分为2组,治疗组60例予子午流注纳子法穴位贴敷联合穴位药熨治疗,对照组60例予多潘立酮片治疗,2组均治疗28天。比较2组疗效;比较2组治疗前后主要症状评分变化;比较2组治疗前后焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分变化。结果治疗组总有效率96.67%(58/60),对照组总有效率76.67%(46/60),治疗组疗效优于对照组(P<0.05)。2组治疗后各项主要症状评分及总积分均较本组治疗前降低(P<0.05),治疗后治疗组各项主要症状评分及总积分均低于对照组(P<0.05)。2组治疗后SAS评分、SDS评分均较本组治疗前降低(P<0.05),治疗后治疗组SAS评分、SDS评分均低于对照组(P<0.05)。结论子午流注纳子法穴位贴敷联合穴位药熨治疗脾胃虚寒型FD疗效显著,可改善患者主要症状及焦虑、抑郁状态。

通络祛痛膏循经取穴贴敷对腰间盘突出患者止痛效果的随机对照研究

目的通过随机对照研究通络祛痛膏循经取穴贴敷对腰间盘突出患者止痛效果。方法110例腰间盘突出患者,采用随机数字表法分为观察组和对照组,每组55例。观察组采用循经取穴贴敷通络祛痛膏,对照组采用常规阿是穴贴敷通络祛痛膏。比较两组患者治疗前后及随访期间视觉模拟评分法(VAS)评分、伴随症状缓解效果、安全性。结果治疗前,观察组患者VAS评分(5.98±1.84)分与对照组的(6.10±2.20)分比较,无明显差异(P>0.05)。治疗后,两组患者VAS评分均低于治疗前,且观察组患者VAS评分(2.93±1.30)分低于对照组的(3.97±2.29)分(P<0.05)。观察组治疗后2周、1个月、3个月随访VAS评分分别为(2.79±1.68)、(2.67±1.38)、(2.37±1.95)分,均低于治疗前(P<0.05),略低于治疗后,但无明显差异(P>0.05)。对照组患者治疗后2周、1个月、3个月随访VAS评分分别为(3.67±2.54)、(4.67±2.63)、(4.59±2.98)分,治疗后2周随访VAS评分略低于治疗后,治疗后1、3个月随访VAS评分均高于治疗后,但均无明显差异(P>0.05)。观察组治疗后2周、1个月、3个月随访VAS评分均低于对照组(P<0.05)。观察组患者伴随症状缓解显效率94.6%高于对照组的76.4%(P<0.05)。观察组与对照组患者伴随症状缓解总有效率均为98.2%,无明显差异(P>0.05)。治疗过程中两组各发生轻度皮肤瘙痒3例,局部涂抹药膏后缓解,局部皮肤后期有轻微结痂,无感染及瘢痕产生。两组均未发生严重安全性问题,两组安全性比较无明显差异(P>0.05)。结论通络祛痛膏循经取穴贴敷疗法对腰间盘突出患者止痛效果及远期疗效优于常规阿是穴贴敷,且在改善伴随症状上循经取穴贴敷显效率高于阿是穴贴敷。

温针配合穴位贴敷及药物干预乳腺癌化疗相关性恶心呕吐的临床研究

目的观察温针配合穴位贴敷及药物干预乳腺癌化疗相关性恶心呕吐(chemotherapy induced nausea and vomiting,CINV)的临床疗效。方法将110例乳腺癌术后辅助化疗患者随机分为观察组和对照组,每组55例。对照组于化疗前30 min接受静脉滴注注射用盐酸托烷司琼治疗,观察组在对照组基础上于化疗前1 d接受温针配合穴位贴敷治疗。观察两组化疗前后不同时间点恶心、呕吐反应症状评分及血清5-羟色胺(5-hydroxytryptamine,5-HT)水平的变化情况,并比较两组CINV发生率。结果观察组CINV发生率为34.5%,明显低于对照组的56.4%,差异具有统计学意义(P<0.05)。两组化疗后第3 d恶心、呕吐反应症状评分均较同组化疗前显著上升,化疗后第5、7 d恶心、呕吐反应症状评分均较同组化疗第3 d显著下降,差异均具有统计学意义(P<0.05)。观察组化疗后第3、5、7 d恶心、呕吐反应症状评分均明显低于对照组,差异均具有统计学意义(P<0.05)。两组化疗后第7 d血清5-HT水平均较同组化疗前显著上升(P<0.05)。观察组化疗后第7 d血清5-HT水平明显低于对照组,差异具有统计学意义(P<0.05)。结论温针配合穴位贴敷及药物干预能降低乳腺癌CINV的发生率,有助于缓解恶心、呕吐症状,其机制可能与降低5-HT水平有关。

耳穴贴压在血瘀耳窍型突发性耳聋患者中的应用效果

目的 研究耳穴贴压在血瘀耳窍型突发性耳聋患者中的干预效果。方法 以江苏省东台市中医院于2022年4月至2023年5月收治的116例血瘀耳窍型突发性耳聋患者为研究对象,使用随机数表法将其分别纳入观察组和对照组,各58例。2组均接受常规综合治疗,观察组加用耳穴贴压。对比2组的听力损失程度、纯音听阈、心理状态和临床疗效。结果 观察组在治疗3周后的听力损失程度较对照组而言相对更轻,且组间比较存在统计学差异(P<0.05)。2组在治疗1周和3周后的纯音听阈均较治疗前下降,观察组在治疗1周和3周后的纯音听阈均较对照组而言相对更优,且差异均存在统计学意义(P均<0.05)。2组在治疗3周后的焦虑自评量表(SAS)和抑郁自评量表(SDS)评分均较治疗前下降,观察组在治疗3周后的SAS、SDS评分均较对照组而言相对更低,且差异均存在统计学意义(P均<0.05)。观察组在治疗3周后的总有效率为93.10%,较对照组的79.31%而言相对更高,且组间比较存在统计学差异(P<0.05)。结论 针对血瘀耳窍型突发性耳聋患者的治疗加用耳穴贴压,不仅能促进患者听力的进一步恢复,还能改善其心理状态和纯音听阈,以及实现临床疗效的提高。

针刺结合引火归元穴位贴敷治疗上实下虚型颈性眩晕临床观察

目的观察针刺结合引火归元穴位贴敷治疗上实下虚型颈性眩晕的临床效果。方法选取120例上实下虚型颈性眩晕患者,按随机数字表法分为针刺组、引火归元组、针刺+引火归元组与西药组并行相应治疗,每组30例。比较四组治疗前后颈性眩晕症状与功能评估量表评分、血清内皮型一氧化氮合酶(eNOS)及人降钙素基因相关肽(CGRP)水平变化,治疗结束后3个月进行回访比较复发率。结果治疗后,四组颈性眩晕症状与功能评估量表评分均较治疗前显著升高,且针刺+引火归元组升高幅度大于其余三组(P<0.05);四组血清eNOS、CGRP水平均较治疗前显著升高,且针刺+引火归元组升高幅度大于其余三组。治疗结束3个月后,针刺+引火归元组复发率为26.67%(8/30),低于其余三组。结论常规针刺、引火归元穴位贴敷、针刺结合引火归元穴位贴敷与口服甲磺酸倍他司汀片等方法对上实下虚型颈性眩晕患者均疗效确切,且针刺结合引火归元穴位贴敷效果最优、复发率最低,值得推广。

中医特色护理在痛风性关节炎中的应用研讨

目的针对痛风性关节炎(GA)患者在常规护理基础上联合中医特色护理,观察其对患者日常生活活动能力、生活质量的影响。方法收集2021年7月至2023年1月我院GA患者(n=60)进行前瞻性研究,采用随机数字表法将患者分为两组。对照组采用常规护理,内容包括生活起居、饮食、运动、心理、疼痛指导、穴位贴敷,观察组在此基础上联合耳部全息铜砭刮痧。比较两组护理前后Barthel评分、关节肿胀与疼痛程度(VAS量表),采用问卷调查患者满意度并进行比较。结果护理前组间Barthel、关节肿胀及疼痛评分比较结果为P>0.05;经过不同方案的护理之后,观察组Barthel评分高于对照组与护理前,关节肿胀、疼痛评分低于对照组与护理前,差异显著(P<0.05);观察组护理满意度为93.33%与对照组的73.33%比较,差异明显(P<0.05)。结论中医特色护理有利于改善GA患者临床症状,减轻关节肿胀及疼痛程度,提高患者日常生活活动能力,患者满意度高。

消癌止痛散穴位贴敷联合埋针疗法对结直肠癌术后患者疼痛以及胃肠功能的意义分析

目的 分析消癌止痛散穴位贴敷联合埋针疗法对结直肠癌术后患者疼痛以及胃肠功能的意义。方法 选取60例结直肠癌手术患者,随机分为对照组和试验组,每组30例。对照组采取临床常规治疗,试验组在对照组基础上术后采取消癌止痛散穴位贴敷联合埋针疗法治疗。比较两组患者胃肠功能恢复情况、临床治疗效果、临床疼痛情况。结果 试验组患者临床治疗效果优于对照组患者,差异有统计学意义(P<0.05)。试验组患者胃肠功能恢复时间、肠鸣恢复时间、首次肛门排气时间、首次排便时间分别为(4.79±0.45)、(2.11±0.18)、(2.67±0.55)、(3.12±1.01)d,均短于对照组患者的(7.99±0.51)、(3.75±0.42)、(3.20±0.66)、(4.21±1.03)d,差异有统计学意义(P<0.05)。试验组患者术后第1、2、3天的视觉模拟评分法(VAS)评分分别为(5.62±0.15)、(3.30±0.12)、(1.62±0.15)分,均低于对照组患者的(6.61±0.13)、(5.35±0.21)、(3.66±0.13)分,差异有统计学意义(P<0.05)。结论 消癌止痛散穴位贴敷联合埋针疗法对结直肠癌术后患者临床效果显著,可缓解患者疼痛程度,促进患者尽快恢复,值得推广。

清金化痰汤联合穴位贴敷治疗小儿难治性支原体肺炎临床观察

目的:观察中西医结合治疗小儿难治性支原体肺炎的临床疗效。方法:选取符合纳入标准的难治性小儿支原体肺炎患儿91例,随机分为对照组44例,予阿奇霉素联合甲泼尼龙治疗;治疗组47例,在对照组基础上联合清金化痰汤及穴位敷贴治疗,14天后观察两组患儿的临床疗效。结果:治疗组总有效率为91.49%,明显高于对照组的72.73%,差异具有统计学意义(P﹤0.05);在改善难治性支原体肺炎的主要症状、生活质量以及促进病灶吸收等方面优于对照组,差异均有统计学意义(P﹤0.05)。结论:清金化痰汤联合穴位贴敷治疗小儿难治性支原体肺炎疗效较好。

中药穴位贴敷联合红外光照射治疗糖尿病周围神经病变的应用研究

目的探究中药穴位贴敷联合红外光照射在治疗糖尿病周围神经病变(DPN)中的应用效果。方法选取2023年4—12月本院收治的180例糖尿病伴有周围神经病变的患者为研究对象,并按照随机分组的原则分为观察组和对照组,每组90例。观察组接受健康教育、糖尿病饮食、适宜运动以及硫辛酸静脉输注治疗,并同时使用常规降糖药。观察组在此基础上,采用红外光局部照射和中药穴位贴敷治疗。通过多伦多临床评分(TCSS)评估DPN的临床症状和严重程度,观察并记录震动感觉阈值(VPT)和肌电图检查有效情况和神经病变症状发生情况。结果治疗后,两组TCSS评分均有所降低,且观察组低于对照组(P<0.05)。在神经病变发生情况方面,观察组显著低于对照组(P<0.05)。在VPT和肌电图检查后的有效情况比较中,观察组患者高于对照组(P<0.05)。结论采用穴位贴敷联合红外光照射治疗DPN患者,可以减轻患者的疼痛,降低医疗成本,并提高治疗水平和效率。此外,该治疗方案还有助于减轻患者及其家属的心理负担,并防止糖尿病并发症的发生,值得在临床实践中推广和使用。

中药热奄包联合足底穴位敷贴治疗高原原发性失眠症疗效及对患者睡眠效率、生活质量的影响

目的:研究中药热奄包联合足底穴位敷贴治疗高原原发性失眠症(PI)的效果及其对患者睡眠效率和生活质量的影响。方法:选取62例高原PI患者,应用随机数字表法分为两组,观察组和对照组各31例。对照组接受艾司唑仑治疗,观察组在此基础上采用中药热奄包联合足底穴位敷贴,两组均治疗2个月。比较两组患者疗效、睡眠效率、睡眠质量及生活质量等。结果:观察组治疗总有效率高于对照组(P<0.05);治疗后,观察组睡眠总时间(TST)、睡眠维持率(SE)、快动眼睡眠相潜伏期(RL)均高于对照组,觉醒时间(AWT)、睡眠潜伏期(SL)、觉醒次数(AT)均小于对照组(P<0.05);治疗后,观察组匹兹堡睡眠质量指数(PSQI)各项评分和PSQI总评分低于对照组(P<0.05);治疗后,观察组世界卫生组织生存质量简表(WHOQOL-BREF)各项评分及总评分均高于对照组(P<0.05)。结论:中药热奄包联合足底穴位敷贴治疗高原原发性失眠症明显提高临床疗效,提升睡眠效率,改善PSQI评分,增加生活质量。

扁桃体啄治联合穴位贴敷治疗儿童阻塞性睡眠呼吸暂停低通气综合征的疗效观察

目的 观察扁桃体啄治联合穴位贴敷治疗儿童阻塞性睡眠呼吸暂停低通气综合征的临床疗效。方法将儿童阻塞性睡眠呼吸暂停低通气综合征患者60例,随机分为治疗组和对照组,每组30例。治疗组采用扁桃体啄治疗法配合穴位贴敷治疗,对照组采用扁桃体啄治疗法配合糠酸莫米松鼻喷雾剂治疗。观察两组治疗前后症状及体征评分的变化,并比较两组临床疗效。结果 两组治疗后症状与体征评分低于治疗前(P<0.05);治疗组除扁桃体肿大评分外,其余症状与体征评分均低于对照组(P<0.05)。两组临床疗效比较,差异有统计学意义(P<0.05)。结论 扁桃体啄治联合穴位贴敷治疗儿阻塞性睡眠呼吸暂停低通气综合征临床疗效可靠。

耳穴贴压联合五音疗法干预大学生肝郁化火型亚健康失眠临床研究

目的 探讨耳穴贴压联合五音疗法干预大学生亚健康失眠(肝郁化火型)的临床疗效。方法 将符合标准亚健康失眠(肝郁化火型)的62例大学生随机分为治疗组和对照组,每组各31例。治疗组采用耳穴贴压联合五音疗法进行干预治疗,7 d为一个疗程,共治疗2个疗程;对照组未采取任何干预措施。试验结果采用匹兹堡睡眠质量指数(pittsburgh sleep quality index, PSQI)、有效率、复发率以及患者反馈等指标进行综合评价,治疗结束后随访一个月的复发情况。结果 研究期间脱落5例视为无效病例,实际获得有效统计样本量57例,其中治疗组27例,对照组30例。治疗前,两组大学生PSQI评分无统计学差异(P>0.05);治疗后,治疗组大学生PSQI评分明显低于对照组(P<0.05),且治疗组的总有效率为92.60%(25/27),高于对照组40%(12/30)。两组治疗前后评分差值比较,治疗组评分下降的差值大于对照组(P<0.05)。治疗组经30 d随访复发率为18.18%(4/22)。结论 耳穴贴压联合五音疗法能有效缓解大学生亚健康失眠(肝郁化火型)的临床症状,提高睡眠质量,治愈后复发率较低,患者青睐度高,推荐临床选用。

严氏苍山太阳炷燎穴位敷贴治疗阳虚血瘀型慢性心力衰竭的临床研究

目的观察严氏苍山太阳炷燎穴位敷贴治疗阳虚血瘀型慢性心力衰竭的临床疗效。方法将145例阳虚血瘀型慢性心力衰竭患者随机分为对照组73例、治疗组72例,两组均给予标准化西药治疗,对照组加用空白自发热贴膏,治疗组加用“严氏苍山太阳炷燎穴位敷贴”药物自发热贴膏,两组疗程均为90 d。观察临床疗效,比较中医证候积分、中医主次症与兼症分层、明尼苏达心力衰竭生活质量量表(MLHFQ)评分、纽约心脏病协会(NYHA)心功能分级、6 min步行试验(6MWT)距离以及B型钠尿肽(BNP)水平等指标的变化情况。结果①试验过程中,对照组脱落8例、治疗组脱落7例,最终完成试验者130例,其中治疗组65例、对照组65例。②治疗前后组内比较,两组中医证候积分均降低(P<0.05);组间治疗后比较,治疗组积分下降更为明显(P<0.05)。③治疗后,治疗组中医主次症与兼症分层得到改善(P<0.05),且治疗组的改善情况优于对照组(P<0.05)。④治疗前后组内比较,两组MLHFQ评分均降低(P<0.05);组间治疗后比较,治疗组MLHFQ评分较对照组显著降低(P<0.05)。⑤治疗后,两组NYHA心功能分级均得到改善(P<0.05),且治疗组的改善情况优于对照组(P<0.05)。⑥治疗前后组内比较,两组6MWT距离均较治疗前增加(P<0.05);组间治疗后比较,治疗组6MWT距离增加较对照组更明显(P<0.05)。⑦治疗前后组内比较,两组BNP水平均降低(P<0.05);组间治疗后比较,治疗组BNP水平显著低于对照组(P<0.05)。⑧两组各项安全性指标均未见明显异常。结论严氏苍山太阳炷燎穴位敷贴对阳虚血瘀型慢性心力衰竭患者临床症状与BNP的改善、运动耐量的提升及生活质量的提高都具有积极促进作用,且安全性好。

揿针联合穴位贴敷治疗对胃肠道肿瘤化疗患者胃肠道反应及睡眠质量的影响

目的 探讨胃肠道肿瘤化疗患者应用揿针联合穴位贴敷治疗对胃肠道反应及睡眠质量的影响效果。方法 选择河南省肿瘤医院中西结合科住院的胃肠道肿瘤化疗患者96例(2021年10月至2023年6月入组)患者研究,参照计算机数字表法分为2组,每组48例,包括对照组(穴位贴敷治疗)与试验组(揿针联合穴位贴敷治疗)。比较干预前后2组患者胃肠道反应及睡眠质量的变化。结果 治疗前,2组恶心程度评分、呕吐程度评分、食欲情况评分差异无统计学意义(P>0.05),治疗5 d、治疗7 d 2组均有改善,且试验组恶心程度评分、呕吐程度评分、食欲情况评分更低,差异有统计学意义(P<0.05);治疗7 d,试验组恶心频率与呕吐频率均低于对照组(P<0.05);治疗前,2组睡眠质量差异无统计学意义(P>0.05),治疗7 d试验组睡眠质量PSQI评分低于对照组(P<0.05);试验组总并发症发生率比对照组低(P<0.05)。结论 胃肠道肿瘤化疗患者应用揿针联合穴位贴敷治疗可以更好地减轻化疗所致的胃肠道反应,改善食欲及睡眠质量,值得应用。