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EFFECT OF ACUPUNCTURE ON SERUM INTERLUKIN-6 IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS
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作者 李祥炜 王玲玲 刘跃光 《World Journal of Acupuncture-Moxibustion》 2002年第1期24-25,共2页
Objective: To observe the effect of acupuncture on serum interlukin-6 (IL-6) level in women with postmenopausal osteoporosis. Methods: 59 cases of postmenopausal osteoporosis women were randomly divided into acupunctu... Objective: To observe the effect of acupuncture on serum interlukin-6 (IL-6) level in women with postmenopausal osteoporosis. Methods: 59 cases of postmenopausal osteoporosis women were randomly divided into acupunctue group(n= 32) and calcium D group(n= 27). In acupuncture group, Zusanli (ST 36), Sanyinjiao (SP 6),Shenshu (BL 23) and Pishu (BL 20) were punctured, 3 times every week, continuously for 6 months. In control group,patients were ordered to take Calcium D, one pill (containing 1500 mg calcium carbonate and VitD3) every morning,continuously for 6 months. Serum IL-6 was detected using radioimmunoassay. Results:After six months' treatment, the result showed that in acupuncture group serum IL-6 calcium level lowered while in control group serum IL-6 content increased. Statistical analysis indicates that there are no significant differences between two groups or between pretreatment and post-treatment in every single group(P >0.05). Conclusion: Although no statistical difference was found between two groups, acupuncture could decrease secretion of IL-6 in postmenopausal osteoporosis women to a certain degree, refrain the activity of osteoclast and improve the quality of bone. 展开更多
关键词 针刺疗法 白细胞介素6 绝经 骨质疏松
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“双固一通”针法对绝经后骨质疏松症模型大鼠骨组织白细胞介素-6mRNA表达水平的影响 被引量:7
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作者 鲍圣涌 王华 +2 位作者 林婉娟 张少君 梁凤霞 《中华中医药杂志》 CAS CSCD 北大核心 2009年第1期84-87,共4页
目的:探讨"双固一通"针法治疗绝经后骨质疏松症(PMO)的可能作用机制。方法:采用60只6月龄雌性SD大鼠,切除双侧卵巢后饲养90d,造成实验性骨质疏松症动物模型,然后随机分成对照组、常规取穴组、双固组、一通组、双固一通组5组,... 目的:探讨"双固一通"针法治疗绝经后骨质疏松症(PMO)的可能作用机制。方法:采用60只6月龄雌性SD大鼠,切除双侧卵巢后饲养90d,造成实验性骨质疏松症动物模型,然后随机分成对照组、常规取穴组、双固组、一通组、双固一通组5组,每组12只。对照组不做任何治疗;常规取穴组取背俞穴"脾俞"、"胃俞"、"肾俞","气海俞";双固组取"关元"、"足三里";一通组取"肾俞"、"膈俞"、"大杼";双固一通组取"关元"、"足三里"、"肾俞"、"膈俞"、"大杼"。电针治疗每天1次,每次15min,留针10min,连续治疗6d后休息1d,连续治疗12周。利用RT-PCR技术检测IL-6 mRNA在骨组织细胞的分布。结果:与对照组比较,所有针刺组的IL-6 mRNA表达均减弱(P<0.05),双固一通组表达明显减弱(P<0.01);双固一通组较常规取穴组、双固组、一通组减弱(P<0.05);常规取穴组、双固组、一通组三组之间比较无显著性差异(P>0.05)。结论:针刺能够降低绝经后骨质疏松症模型大鼠骨组织的IL-6 mRNA表达水平,且"双固一通"针法优于其他三治疗组。 展开更多
关键词 绝经后骨质疏松症 针刺疗法 白细胞介素-6 去卵巢大鼠 实验研究
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