AGN and 34 healthy children were investigated in this study to research FRs and PGs roles in the patbyphysiology process with AGN.We measured the plasma levels of TXB2,6-KPGF1a,LPO, SOD,GSH-px,etc.by radioimmunoassay ...AGN and 34 healthy children were investigated in this study to research FRs and PGs roles in the patbyphysiology process with AGN.We measured the plasma levels of TXB2,6-KPGF1a,LPO, SOD,GSH-px,etc.by radioimmunoassay method.The result showed that,in acute phase of AGN,the level of LPO and TXB2 increased(P< 0. 01,P<0.001),but that of GSH-px and 6KPGF1a decreased(both P<0.001 )significantly. Meanwhile, there was a significant positive correlation between LPO and TXB2(r=0. 475,P<0.001 ), and a negative correlation between LPO and 6-KPGF1a(r=-0. 636,P<0. 001).All these indicate that FRs and PGs were all involved in the process of AGN and FRs destroyed renal tissue and physiology function themselves or by PGs generating.展开更多
in this study serum complement mediated immune complex solubilizing capacity (CMSC) and immune complement precipitation capacity (ICPIC) of 32 children with acute glomerulonephritis (AGN) were measured. The data showe...in this study serum complement mediated immune complex solubilizing capacity (CMSC) and immune complement precipitation capacity (ICPIC) of 32 children with acute glomerulonephritis (AGN) were measured. The data showed that the level of serum CMSC and ICPIC was markedly decreased in acute phase and returned to normal in the 7th week after onset of disease.Correlation analysis revealed that there were positive correlation between the level of serum CMSC and ICPIC and the serum concentration of CH50, C3, C4, but no linear correlation between the level of serum CMSC and ICPIC and the amount of CIC. These results suggest that the declined serum CMSC and ICPIC in AGN may be associ ated with the pathogenesis of AGN.展开更多
文摘AGN and 34 healthy children were investigated in this study to research FRs and PGs roles in the patbyphysiology process with AGN.We measured the plasma levels of TXB2,6-KPGF1a,LPO, SOD,GSH-px,etc.by radioimmunoassay method.The result showed that,in acute phase of AGN,the level of LPO and TXB2 increased(P< 0. 01,P<0.001),but that of GSH-px and 6KPGF1a decreased(both P<0.001 )significantly. Meanwhile, there was a significant positive correlation between LPO and TXB2(r=0. 475,P<0.001 ), and a negative correlation between LPO and 6-KPGF1a(r=-0. 636,P<0. 001).All these indicate that FRs and PGs were all involved in the process of AGN and FRs destroyed renal tissue and physiology function themselves or by PGs generating.
文摘in this study serum complement mediated immune complex solubilizing capacity (CMSC) and immune complement precipitation capacity (ICPIC) of 32 children with acute glomerulonephritis (AGN) were measured. The data showed that the level of serum CMSC and ICPIC was markedly decreased in acute phase and returned to normal in the 7th week after onset of disease.Correlation analysis revealed that there were positive correlation between the level of serum CMSC and ICPIC and the serum concentration of CH50, C3, C4, but no linear correlation between the level of serum CMSC and ICPIC and the amount of CIC. These results suggest that the declined serum CMSC and ICPIC in AGN may be associ ated with the pathogenesis of AGN.
