Rationale:Multi-organ failure is a symptom of paraquat poisoning,resulting in high mortality and morbidity rates.Though paraquat is widely available,poisoning through inhalation is rare.Patient’s Concern:A 37-year-ol...Rationale:Multi-organ failure is a symptom of paraquat poisoning,resulting in high mortality and morbidity rates.Though paraquat is widely available,poisoning through inhalation is rare.Patient’s Concern:A 37-year-old male reported to the emergency department with complaints of vomiting after an alleged history of inhalation of paraquat while at work.Diagnosis:Paraquat poisoning.Interventions:Supportive management along with multiple sessions of hemodialysis.Outcomes:Renal complications caused by paraquat were improved after multiple sessions of hemodialysis.However,the patient developed respiratory complications and later due to persistent hypoxemia and non-responsive to supportive therapy,he succumbed to his illness.Lessons:Acute kidney injury is a complication of paraquat poisoning.However,kidney involvement with the inhalational mode is rare.It is caused by reduction and oxidation cycles,as well as the formation of reactive oxygen species,necessitating hemodialysis as the treatment.Without a clear history,a specific clinical trait,or a diagnostic test,diagnosis can be difficult.Our case thus highlights the inhaled paraquat poisoning,presenting with acute kidney injury with late respiratory impairment as a consequence.展开更多
目的探讨分析急性百草枯中毒预后影响因素,为早期判定预后、指导临床治疗提供依据。方法收集85例急性百草枯中毒患者临床资料,通过多元逻辑回归分析比较患者预后与上述资料间的关系,得出显著影响因素。计算显著影响因素的死亡/存活的95...目的探讨分析急性百草枯中毒预后影响因素,为早期判定预后、指导临床治疗提供依据。方法收集85例急性百草枯中毒患者临床资料,通过多元逻辑回归分析比较患者预后与上述资料间的关系,得出显著影响因素。计算显著影响因素的死亡/存活的95%置信区间。结果患者服毒量、白细胞计数、中性粒细胞百分比、肌酐、尿素氮(BUN)、血清药物浓度、Lac、百草枯中毒严重指数(Severity index of paraquat poisoning,SIPP)与预后具有显著相关性。逻辑回归模型对"死亡"的预测准确率为84.6%;对"存活"的预测准确率为91.3%,总的预测准确率为88.2%。展开更多
文摘Rationale:Multi-organ failure is a symptom of paraquat poisoning,resulting in high mortality and morbidity rates.Though paraquat is widely available,poisoning through inhalation is rare.Patient’s Concern:A 37-year-old male reported to the emergency department with complaints of vomiting after an alleged history of inhalation of paraquat while at work.Diagnosis:Paraquat poisoning.Interventions:Supportive management along with multiple sessions of hemodialysis.Outcomes:Renal complications caused by paraquat were improved after multiple sessions of hemodialysis.However,the patient developed respiratory complications and later due to persistent hypoxemia and non-responsive to supportive therapy,he succumbed to his illness.Lessons:Acute kidney injury is a complication of paraquat poisoning.However,kidney involvement with the inhalational mode is rare.It is caused by reduction and oxidation cycles,as well as the formation of reactive oxygen species,necessitating hemodialysis as the treatment.Without a clear history,a specific clinical trait,or a diagnostic test,diagnosis can be difficult.Our case thus highlights the inhaled paraquat poisoning,presenting with acute kidney injury with late respiratory impairment as a consequence.
文摘目的探讨分析急性百草枯中毒预后影响因素,为早期判定预后、指导临床治疗提供依据。方法收集85例急性百草枯中毒患者临床资料,通过多元逻辑回归分析比较患者预后与上述资料间的关系,得出显著影响因素。计算显著影响因素的死亡/存活的95%置信区间。结果患者服毒量、白细胞计数、中性粒细胞百分比、肌酐、尿素氮(BUN)、血清药物浓度、Lac、百草枯中毒严重指数(Severity index of paraquat poisoning,SIPP)与预后具有显著相关性。逻辑回归模型对"死亡"的预测准确率为84.6%;对"存活"的预测准确率为91.3%,总的预测准确率为88.2%。
