Insatiable Narcissism Underlying Addictive Behavior: Outline of a Biosystematic Model

This study is a contribution to basic research on narcissism shown on addictive behavior. A new biosystematic model of narcissism underlying addictive behavior is outlined. Basically, normal narcissism is defined as the self-reference of living systems maintaining their circular organization and identity. The communication between narcissistic systems follows the narcissistic logic of fitting or non-fitting of structures (a third possibility is excluded) shown on geometric diagrams. From this model of narcissistic interactions with the environment, addictive behavior is deduced. If the narcissistic desire for the ideal objects cannot be satisfied in the environment, the narcissist attempts to cope with this lack of intended objects by abuse of addictive substances. This leads to an overexpression of receptors in pertinent brain areas that may underly craving on the behavioral level, interpreted as pseudo satisfaction of narcissistic desires—destiny becomes an addiction. In conclusion, the significance of the biosystematic model of narcissism for the understanding of addictive communication and the psychopathology of depression is briefly discussed.

Health correlates, addictive behaviors, and peer victimization among adolescents in China

Background Peer victimization has been recognized as a common social problem affecting children and adolescents in all parts of the world. This study aims to examine the prevalence of different types of peer victimization and to evaluate the associations between peer victimization and health correlates. Methods Using a large population sample of 18,341 adolescents aged 15–17 years from 6 cities in China, this study esti-mated the prevalence of different types of peer victimization, addictive behaviors, and health-related variables with self-administrated questionnaires. A three-phase logistical regression analysis was conducted to investigate the associations between peer victimization and addictive behaviors as well as health-related factors among adolescents. Results A total of 42.9% of the surveyed Chinese adolescents have been bullied by peers, with boys reporting higher rate on overt victimization (36.9%) and girls on relational forms (33.9%). School environment (34.7%) was the most frequent scene of peer violence, followed by neighborhood, family, and internet. Addictive behaviors except substance abuse were found related to higher possibility of peer victimization (aOR 1.21–1.73, P<0.001). Peer victimization was significantly associated with more depressive symptoms, post-traumatic stress disorder symptoms, and suicide ideation and deliberate self-harm (aOR 1.05–2.27, P<0.001), and poorer self-esteem and health-related quality of life (aOR 0.95–0.97, P<0.001). Conclusion Possible explanations of the associations found in this study are discussed and implications for future services are raised.

Comparison of brain functions between healthy participants and methamphetamine users with various addiction histories:Data analysis based on EEG and fNIRS

The electroencephalogram(EEG)rhythm and functional near-infrared spectroscopy(fNIRS)activation levels have not been compared between a healthy control group(HCG)and methamphetamine user group(MUG)with different addiction histories.This study used 64-electrode EEG and fNIRS to conduct an experiment that analyzed the resting and craving states.The EEG and fNIRS data of 56 participants were collected,including 14 healthy participants,14 methamphetamine users with an addiction history of 0.5–5 years,14 users with an addiction history of 5–10 years,and 14 users with an addiction history of 10–15 years.Isolated effective coherence(iCoh)within the brain network was used to process the EEG data.Statistical analysis was performed to compare differences in iCoh among the delta,theta,alpha,beta,and gamma bands and explore oxyhemoglobin activation levels in the ventrolateral prefrontal cortex,dorsolateral prefrontal cortex,orbitofrontal cortex,and frontopolar prefrontal cortex(FPC)of the control group.Finally,the Kmeans,Gaussian mixed model(GMM),linear discriminant analysis(LDA),support vector machine(SVM),Bayes,and convolutional neural networks(CNN)algorithms were used to classify methamphetamine users based on drug and neutral images.A 3-class accuracy was achieved.Changes in EEG and fNIRS activation levels of HCG and MUG with varied addiction histories were demonstrated.

Validity,Reliability,and Measurement Invariance of the Thai Smartphone Application-Based Addiction Scale and Bergen Social Media Addiction Scale

Background:In recent years,there has been increased research interest in both smartphone addiction and social media addiction as well as the development of psychometric instruments to assess these constructs.However,there is a lack of psychometric evaluation for instruments assessing smartphone addiction and social media addiction in Thailand.The present study evaluated the psychometric properties and gender measurement invariance of the Thai version of the Smartphone Application-Based Addiction Scale(SABAS)and Bergen Social Media Addiction Scale(BSMAS).Method:A total of 801 Thai university students participated in an online survey from January 2022 to July 2022 which included demographic information,SABAS,BSMAS,and the Internet Gaming Disorder Scale-Short Form(IGDS9-SF).Results:Confirmatory Factor Analyses(CFAs)found that both the SABAS and BSMAS had a one-factor structure.Findings demonstrated adequate psychometric properties of both instruments and also supported measurement invariance across genders.Moreover,scores on the SABAS and BSMAS were correlated with scores on the IGDS9-SF.Conclusion:The results indicated that the SABAS and BSMAS are useful psychometric instruments for assessing the risk of smartphone addiction and social media addiction among Thai young adults.

The Role of Impulsivity and Addiction in Gambling Behaviors: How Applied Neuroscience Research Can Help in the Monitoring and Management of Mental Health Issues

One in five Americans experience symptoms associated with at least one mental health disorder every year. These include behavioral addictions, which have long been overlooked despite their similar neural bases with substance addictions. Gambling addiction, a type of behavioral addiction, deserves particular attention given the significant negative effects, this addiction has on financial and interpersonal health. The purpose of this paper is to review the available literature concerning the behavioral and neural processes involved in gambling addiction, including: the anticipation of reward, the role of dopamine, and the neural substrates of the decision-making processes involved in gambling addiction. Market research has also identified solutions that integrate applied neuroscience and self-tracking systems to monitor and manage mental health issues associated with gambling addiction. The authors then propose a gambling treatment-focused mobile app solution that addresses outstanding issues with a special design aimed at reversing plasticity in order to relieve the effects of gambling addiction. .

Reanalysis of Cigarettes Confirms Increased Addictive Nicotine

吸烟对人健康的危害不言而喻,"戒烟"也早已成为关注公众健康的各国政府努力的方向。然而面对席卷全球的戒烟浪潮的烟草商们却在悄悄采取策略以保障他们的收益:他们增加每根香烟中尼古丁的含量,刻意延长人们吸一支烟的时间,或是增加吸烟时吞吐烟雾的次数。烟草商的目的只有一个,即千方百计诱使人们对香烟更加上瘾!针对这种现象,人们不得不呼吁司法层面的监控。

In-situ deposition of apatite layer to protect Mg-based composite fabricated via laser additive manufacturing

Biodegradable magnesium(Mg) and its alloy show huge potential as temporary bone substitute due to the favorable biocompatibility and mechanical compatibility. However, one issue deserves attention is the too fast degradation. In this work, mesoporous bioglass(MBG)with high pore volume(0.59 cc/g) and huge specific surface area(110.78 m^(2)/g) was synthesized using improved sol-gel method, and introduced into Mg-based composite via laser additive manufacturing. Immersion tests showed that the incorporated MBG served as powerful adsorption sites, which promoted the in-situ deposition of apatite by successively adsorbing Ca2+and HPO42-. Such dense apatite film acted as an efficient protection layer and enhanced the corrosion resistance of Mg matrix, which was proved by the electrochemical impedance spectroscopy measurements. Thereby, Mg based composite showed a significantly decreased degradation rate of 0.31 mm/year. Furthermore,MBG also improved the mechanical properties as well as cell behavior. This work highlighted the advantages of MBG in the fabrication of Mg-based implant with enhanced overall performance for orthopedic application.

Influence of childhood trauma on adolescent internet addiction: The mediating roles of loneliness and negative coping styles

BACKGROUND In the information age,the use of the internet and multimedia tools has large effects on the life of middle school students.Improper use of the internet may result in internet addiction(IA).Thus,actively exploring the factors influencing adolescent and the mechanism of addiction as well as promoting adolescent physical and mental health and academic development are priorities that families,schools,and society urgently need to address.AIM To explore the effect of childhood trauma on adolescent IA and to consider the roles of loneliness and negative coping styles.METHODS A total of 11310 students from six junior high schools in Henan,China,completed the child trauma questionnaire,IA test,loneliness scale,and simple coping style questionnaire.In addition,data were collected from 1044 adolescents with child-hood trauma for analysis with IBM SPSS 26.0 and AMOS 28.0;we examined the relationships among childhood trauma,IA,loneliness,and negative coping styles.RESULTS We found that childhood trauma not only directly affected adolescents’IA but also affected IA through loneliness and negative coping styles.CONCLUSION Therefore,this study has theoretical implications regarding adolescent mental health and may inform interventions for IA.

Resting-state electroencephalography theta predicts neurofeedback treatment 4-month follow-up response in nicotine addiction

Background The high rate of long-term relapse is a major cause of smoking cessation failure.Recently,neurofeedback training has been widely used in the treatment of nicotine addiction;however,approximately 30%of subjects fail to benefit from this intervention.Our previous randomised clinical trial(RCT)examined cognition-guided neurofeedback and demonstrated a significant decrease in daily cigarette consumption at the 4-month follow-up.However,significant individual differences were observed in the 4-month follow-up effects of decreased cigarette consumption.Therefore,it is critical to identify who will benefit from pre-neurofeedback.Aims We examined whether the resting-state electroencephalography(EEG)characteristics from pre-neurofeedback predicted the 4-month follow-up effects and explored the possible mechanisms.Methods This was a double-blind RCT.A total of 60 participants with nicotine dependence were randomly assigned to either the real-feedback or yoked-feedback group.They underwent 6 min closed-eye resting EEG recordings both before and after two neurofeedback sessions.A follow-up assessment was conducted after 4 months.Results The frontal resting-state theta power spectral density(PSD)was significantly altered in the real-feedback group after two neurofeedback visits.Higher theta PSD in the real-feedback group before neurofeedback was the only predictor of decreased cigarette consumption at the 4-month follow-up.Further reliability analysis revealed a significant positive correlation between theta PSD pre-neurofeedback and post-neurofeedback.A leave-one-out cross-validated linear regression of the theta PSD pre-neurofeedback demonstrated a significant correlation between the predicted and observed reductions in cigarette consumption at the 4-month follow-up.Finally,source analysis revealed that the brain mechanisms of the theta PSD predictor were located in the orbital frontal cortex.Conclusions Our study demonstrated changes in the resting-state theta PSD following neurofeedback training.Moreover,the resting-state theta PSD may serve as a prognostic marker of neurofeedback effects.A higher resting-state theta PSD predicts a better long-term response to neurofeedback treatment,which may facilitate the selection of individualised interventions.

Prevalence of social media addiction among nursing students

Objective:The objective of this study was to assess the prevalence and level of social media addiction among nursing students in the Faculty of Nursing,Cairo University.Materials and Methods:A descriptive cross‑sectional research design was conducted on samples of 340 students at the Faculty of Nursing,Cairo University.Data were collected through demographic background information sheet and Social Networking Addiction Scale.Results:All the students were addicted as 6.76%were severely addicted and 60.59%and 32.65%were moderately and mildly addicted,respectively.Significant relations were found between social media addiction and students’age(χ^(2)=11.331,P=0.003),educational level(χ^(2)=20.239,P=0.003),and grade point average(χ^(2)=19.378,P=0.013).Conclusion:Internet addiction was prevalent among all students but at different levels,so early screening of students for Internet addiction using the Internet Addiction Scale is important to provide early treatment and prevent hazards to health.

Prenatal programing of motivated behaviors:can innate immunity prime behavior?

Prenatal programming during pregnancy sets physiological outcomes in the offspring by integrating external or internal stimuli.Accordingly,pregnancy is an important stage of physiological adaptations to the environment where the fetus becomes exposed and adapted to the maternal milieu.Maternal exposure to high-energy dense diets can affect motivated behavior in the offs p ring leading to addiction and impaired sociability.A high-energy dense exposure also increases the pro-inflammatory cytokines profile in plasma and brain and favors microglia activation in the offspring.While still under investigation,prenatal exposure to high-energy dense diets promotes structural abnormalities in selective brain regions regulating motivation and social behavior in the offspring.The current review addresses the role of energy-dense foods programming central and peripheral inflammatory profiles during embryonic development and its effect on motivated behavior in the offspring.We provide preclinical and clinical evidence that supports the contribution of prenatal programming in shaping immune profiles that favor structural and brain circuit disruption leading to aberrant motivated behaviors after birth.We hope this minireview encourages future research on novel insights into the mechanisms underlying maternal programming of motivated behavior by central immune networks.

Epigenetic drug library screening reveals targeting DOT1L abrogates NAD^(+)synthesis by reprogramming H3K79 methylation in uveal melanoma

Uveal melanoma(UM)is the most frequent and life-threatening ocular malignancy in adults.Aberrant histone methylation contributes to the abnormal transcriptome during oncogenesis.However,a comprehensive understanding of histone methylation patterns and their therapeutic potential in UM remains enigmatic.Herein,using a systematic epi-drug screening and a high-throughput transcriptome profiling of histone methylation modifiers,we observed that disruptor of telomeric silencing-1-like(DOT1L),a methyltransferase of histone H3 lysine 79(H3K79),was activated in UM,especially in the high-risk group.Concordantly,a systematic epi-drug library screening revealed that DOT1L inhibitors exhibited salient tumor-selective inhibitory effects on UM cells,both in vitro and in vivo.Combining Cleavage Under Targets and Tagmentation(CUT&Tag),RNA sequencing(RNA-seq),and bioinformatics analysis,we identified that DOT1L facilitated H3K79 methylation of nicotinate phosphoribosyltransferase(NAPRT)and epigenetically activated its expression.Importantly,NAPRT served as an oncogenic accelerator by enhancing nicotinamide adenine dinucleotide(NAD^(+))synthesis.Therapeutically,DOT1L inhibition epigenetically silenced NAPRT expression through the diminishment of dimethylation of H3K79(H3K79me2)in the NAPRT promoter,thereby inhibiting the malignant behaviors of UM.Conclusively,our findings delineated an integrated picture of the histone methylation landscape in UM and unveiled a novel DOT1L/NAPRT oncogenic mechanism that bridges transcriptional addiction and metabolic reprogramming.

Prevalence and Factors Associated with Smartphone Addiction among Adolescents–A Nationwide Study in Malaysia

Smartphone ownership among adolescents is getting common in this decade especially in Malaysia;Adolescent are strongly devoted to their smartphone and this may lead to smartphone addiction.Studies have reported that smartphone addiction has become an emerging social and health problem especially among the youth in many countries however there is lack of study among adolescents in Malaysia.This study aimed to examine the prevalence and factors associated with smartphone addiction among adolescents in Malaysia.This was a cross-sectional study involving adolescents from 15 primary care clinics throughout the country.Respondents were assessed on their smartphone activities using the Malaysian short version of the Smartphone addiction scale(SAS-M-SV).Multiple logistic regression was used to determine the predictors of smartphone addiction among adolescents.The study was conducted among 921 adolescents with 49.6%male(n=457).The mean age of adolescents was 16.4±2.4 years.The ethnicity distribution were 74.6%Malay,7.3%Chinese,4.7%Indian and 13.4%other ethnicities.The prevalence of smartphone addiction was 37.1%(342/921);37.4%in male and 36.9%in female.Based on multiple logistic regression analysis,longer duration of smartphone use per week was associated with higher odds of smartphone addiction among adolescent(odd ratio=1.005%,95%confidence interval=1.000–1.009,p-value=0.039).Smartphone addiction is present in nearly four in ten adolescents in Malaysia.Adolescents who spend longer duration in smartphone usage per week were associated with higher odds of having smartphone addiction.Parents should be more alert and vigilant about this finding.Hence,parents should limit their children from spending too much of time with smartphone in order to prevent their children from getting smartphone addiction.

The Relationship between Dimensions of Emerging Adulthood and Behavioral Problems among Chinese Emerging Adults: The Mediating Role of Physical Activity and Self- Control

Emerging adulthood(EA)is a critical stage of life to develop and sustain a healthy lifestyle,which is also a time of vulnerability to poor physical and mental health outcomes.In this study,we conducted a path analysis(N=1326)to examine associations among four dimensions of EA,levels of regular physical activity(PA),self-control,MPA tendency and irrational procrastination.Results found:1)higher levels of PA predicted both MPA tendency(β=−0.08,95%CI:−0.11 to−0.06,p<0.001)and irrational procrastination(β=−0.01,95%CI:−0.17 to−0.008,p<0.01)indirectly via self-control;2)Instability(β=0.13,95%CI:0.08 to 0.18,p<0.01)and Responsibility(β=−0.06,95%CI:−0.10 to−0.08,p=0.03)exerted direct effects on irrational procrastination and Instability also indirectly predicted irrational procrastination via MPA tendency(β=0.03,95%CI:0.02 to 0.05,p<0.01).These findings proved that perceived features of EA are linked to behavioral problems and supported that regular PA plays a crucial role to protect mental health.

Determinants of internet addiction among medical students in Casablanca: a cross-sectional study

Objective:This study aimed to estimate the prevalence and determinants of Internet addiction among medical students at the Faculty of Medicine and Pharmacy of Casablanca,Morocco.Methods:This was a cross-sectional study conducted among students at the Faculty of Medicine and Pharmacy in Casablanca between October and March 2020.An online questionnaire was administered to students to collect data and internet addiction was assessed by the Young questionnaire.A score threshold≥50 was adopted to define addiction.Univariate and multivariate logistic regression analyses were used to identify factors associated with internet addiction.Results:Out of a total of 4093 FMPC students enrolled in the 2020-2021 academic year,506 agreed to participate in this study,including 303 females and 203 males.The mean addiction score assessed on the Young scale was(49.08±16.11).The prevalence of Internet addiction was 44.5%(225/506,95% CI:40% to 49%).Multiple regression analysis showed that being older than 20 years(OR=0.17,95% CI:0.40 to 0.64),being female(OR=1.70,95% CI:1.04 to 2.78),being in the dissertation year(6th year)(OR=5.17,95% CI:2.23 to 11.44),having a history of psychiatric consultation(OR=2.64,95% CI:1.34 to 5.21),having divorced parents(OR=2.64,95% CI:1.05 to 5.87),use of sleeping medication(OR=2.9,95% CI:1.05 to 3.70),sleep disorders(OR=2.06,95% CI:1.25 to 3.79),sleep deprivation(OR=2.26,95% CI:1.39 to 3.65),excessive daytime sleepiness(OR=5.39,95% CI:2.19 to 13.24),anxiety disorders(OR=1.47,95% CI:1.18 to 2.30),duration of internet connection(>4 h)(OR=11.43,95% CI:4.85 to 27.66),and having frequent conflicts with parents(OR=2.37,95% CI:1.49 to 3.79)and friends(OR=0.26,95% CI:0.11 to 0.65)were independently associated with internet addiction.Conclusion:The prevalence of Internet addiction among medical students in Casablanca remains high.Targeted action on the determinants would be of great value in prevention.

Evaluation of Perinatal and Developmental Outcomes in Neonates with Abstinence Syndrome Admitted to NICU

Drug abuse by pregnant women is one of the significant problems for mothers and their neonates.This study aimed to investigate the effects of maternal substance use disorder during pregnancy on neonatal developmental criteria.In a case-control study,clinical records of 90 neonates diagnosed with neonatal abstinence syndrome who were admitted to NICU in one of four hospitals affiliated with Shahid-Beheshti University of Medical Sciences in Tehran,Iran between 2017 and 2020 were compared to 90 neonates without neonatal abstinence syndrome(control group).Demographic information and data for neonatal developmental characteristics and complications were extracted from the clinical records of this convenience sample.Data for the type and method of maternal substance use during pregnancy were collected through a telephone call with mothers.Our data showed that the prevalence of drug addiction was 1.8%among pregnant women,and the most common drugs used by mothers were opium(n=45%,50%),amphetamine(n=30%,33%),and methadone(n=14%,16%).Neonates with abstinence syndrome had a higher prevalence of transient tachypnea of the newborn(TTN)(P=0.004),and a prevalence of being admitted to NICU(P=0.05)and for a longer duration(P<0.001).Their mothers had a higher prevalence of having pre-eclampsia(P=0.010).Using morphine vs.amphetamine showed no difference based on their effects on mothers and neonates.Substance use during pregnancy increased the prevalence of pregnancy complications(pre-eclampsia)and neonatal complications(TTN and prevalence and duration of hospitalization).Therefore,planning for the development of health policies to raise awareness among women and more broadly,all members of the community,is important to prevent the tendency to engage in this potentially high-risk behavior.

Association between social media addiction and sleep quality among undergraduate nursing students:a cross-sectional study

Objectives:To examine the association between social media addiction and sleep quality among undergraduate nursing students.Methods:This research is an analytical observational study with a cross-sectional approach.The sampling technique was purposive sampling of 150 nursing students at a private university in Malang,Indonesia.Respondents filled out a questionnaire about self-identity,a sleep quality questionnaire from the Pittsburgh Sleep Quality Index(PSQI),and social media addiction from Social Media Addiction Scale(SMAS).This was a bivariate analysis which was conducted using the Pearson Product Moment Correlation test.Results:The results of this study reported that most nursing students were addicted to social media(76%).As for the parameter of the quality variable,most respondents had poor sleep quality,which were about 106 people(70.3%).The result of the Pearson Product Moment Correlation test obtained a P value of 0.000.The Pearson correlation coefficient was 0.358.Social media addiction(adjusted odds ratio[OR]4.80,95%confidence interval[CI]=2.08-11.02),gender(adjusted OR 3.79,95%CI=1.58-9.12),and using social media for a long time(adjusted OR 4.21,95%CI=1.97-10.48)were associated with sleep quality.Conclusions:We found that there is an association between social media addiction and sleep quality among nursing students.Furthermore,we might be educating nursing students to manage their time to improve their quality of sleep to avoid any health problems.

The Relationship between Internet Addiction and Cyberbullying Perpetration: A Moderated Mediation Model of Moral Disengagement and Internet Literacy

Internet addiction and cyberbullying have emerged as significant global mental health concerns in recent years.Although previous studies have shown a close association between Internet addiction and cyberbullying,the underlying mechanisms connecting these two phenomena remain unclear.Therefore,this study aimed to reveal the mechanisms involved between Internet addiction and cyberbullying perpetration from the perspective of cognition function.This study recruited 976 Chinese youth through online survey,using the short version of Internet Addiction Test(s-IAT),Chinese Cyberbullying Intervention Project Questionnaire(C-CIPQ),Cyberbullying Moral Disengagement Scale(CMDS),and Internet Literacy Questionnaire(ILQ)to investigate the relationship between Internet addiction,moral disengagement,Internet literacy and cyberbullying perpetration.The keyfindings of this study were as follows:after controlling gender and age,(1)Internet addiction had a significant positive predictive effect on cyberbullying perpetration;(2)moral disengagement acted as a mediator between Internet addiction and cyberbullying perpetration;and(3)Internet literacy played a moderating role between moral disengagement and cyberbullying perpetration.In conclusion,there was a moderated mediating effect between Internet addiction and cyberbullying perpetration,contributing to a better understanding of the relationship between these two phenomena.

Effects of sports on school adaptability, resilience and cell phone addiction tendency of high school students

BACKGROUND Sport help promote healthy physical and mental development of high school students.To date,there have been few studies on the effect of sport on school adaptability,resilience and cell phone addiction tendency of high school students.AIM To explore the effects of sports on school adaptability,resilience and cell phone addiction of high school students.METHODS A stratified random sampling method was used to select 600 students from two high schools in Lhasa,and Physical Activity Rating Scale,School Adjustment Scale for High School Students,Chinese Adolescents Resilience Scale,and Mobile Phone Addiction Index were used for field questionnaire survey.RESULTS Sport was positively correlated with school adaptability and resilience(P<0.01),school adaptability was positively correlated with resilience(P<0.01)and cell phone addiction was negatively correlated with sports,school adaptability and resilience(P<0.01).The direct effect of sport on cell phone addiction was significant(P<0.001),accounting for 20.51%of the total effect.The mediating effect of school adaptability on sport and cell phone addiction was significant(P<0.001),accounting for 17.38%and 35.36%of the total effect value,respectively.School adjustment and resilience had a significant chain-mediated effect on sport and cell phone addiction(P<0.001),accounting for 26.75%of the total effect.CONCLUSION Sport affected the cell phone addiction tendency of senior high school students through the mediating effect of school adaptability and resilience,and through the chain mediation effect of both.

Correlation analysis of mental health conditions and personality of patients with alcohol addiction

BACKGROUND Alcohol addiction,or alcohol dependence,refers to a psychological state of strong craving for alcohol caused by drinking when both the drinking times and alcohol consumption reach a certain level.Alcohol addiction can cause irreversible damage,leading to mental illness or mental disorders,negative changes in their original personality,and a tendency to safety incidents such as committing suicide or violent attacks on others.Significant attention needs to be given to the mental health of alcohol addicts,which could reflect their abnormal personality traits.However,only a few papers on this issue have been reported in China.AIM To investigate the correlation between mental health and personality in patients with alcohol addiction.METHODS In this single-center observational study,we selected 80 patients with alcohol addiction as the research subjects,according to the criteria of the K10 scale to evaluate the mental health of patients with alcohol addiction,and divided these patients into four groups based on the evaluation results:Good,average,relatively poor and bad.And then analyzed the correlation between mental health conditions and personality characteristics from these four groups of patients.RESULTS The average score of the K10 scale(Kessler 10 Simple Psychological Status Assessment Scale)in 80 patients with alcohol addiction was 25.45 points,the median score was 25 points,the highest score was 50 points,and the lowest score was 11 points.Pearson's analysis showed that the K10 score was positively correlated with the scores of these two subscales,such as the P-subscale and the N-subscale(P<0.05).In contrast,the K10 score had no significant correlation with the scores from the E-subscale and the L-subscale(P>0.05).CONCLUSION The mental health conditions of patients with alcohol addiction are positively correlated with their personality characteristics.