Objective:To study the leaves of Adiantum philippense L.for their antioxidant,cytotoxicity and thrombolytic activities and to perform phytochemical evaluation.Methods:In-vitro antioxidant activity of extract was studi...Objective:To study the leaves of Adiantum philippense L.for their antioxidant,cytotoxicity and thrombolytic activities and to perform phytochemical evaluation.Methods:In-vitro antioxidant activity of extract was studied using DPPH radical scavenging,reducing power,total phenol and total flavonoid content determination assays.The cytotoxic activity was determined using brine shrimp lethality bioassay,thrombolytic activity by clot disruption and phytochemical potential by qualitative analysis.Results:The antioxidant activity of the extracts was found promising.The reducing power of this crude extract increase with the increase of concentration;IC_(50)values of DPPH scavenging activity was(140.00±0.86)μg/mL as compared to ascorbic acid[IC_(50)(130.00±0.76)μg/mL];Total phenol and total flavonoids content were(148.26±0.24)mg/mL and(163.06±0.56)mg/mL respecnvely.In cytotoxicity assay the LC_(50)values of the sample was(106.41±0.78)μg/mL where as for standard vincristin sulphate was(08.50±0.24)μg/mL as a positive control and the extract shows(12.8611.02)%clot lytic whereas standard streptokinase shows(30.86+0.44%clot lytic activity in thrombolytic assay.The phytochemical evaluation indicates the presence of chemical constituents including carbohydrates,alkaloids,saponins,glycosides,flavonoids.Conclusions:This study shows that the methanol extract of leaves of Adiantum philippense L.has bioactivitv but further compound isolation is necessary to confirm the activities of individual compounds.展开更多
利用光学显微镜和扫描电子显微镜对产于广西的3种铁线蕨属植物的孢子形态进行了观察研究,详细描述了3种铁线蕨属植物即铁线蕨A d iantum cap illus-veneris L.、扇叶铁线蕨A.f labellu la tum L.和假鞭叶铁线蕨A.m a lesianum G hatak...利用光学显微镜和扫描电子显微镜对产于广西的3种铁线蕨属植物的孢子形态进行了观察研究,详细描述了3种铁线蕨属植物即铁线蕨A d iantum cap illus-veneris L.、扇叶铁线蕨A.f labellu la tum L.和假鞭叶铁线蕨A.m a lesianum G hatak孢子的形态及表面纹饰特征,讨论了各种间的差异。展开更多
基金Supported by Department of Pharmacy,International Islamic University Chittagong,Bangladesh.Grant No.Pharm-97/06-2012
文摘Objective:To study the leaves of Adiantum philippense L.for their antioxidant,cytotoxicity and thrombolytic activities and to perform phytochemical evaluation.Methods:In-vitro antioxidant activity of extract was studied using DPPH radical scavenging,reducing power,total phenol and total flavonoid content determination assays.The cytotoxic activity was determined using brine shrimp lethality bioassay,thrombolytic activity by clot disruption and phytochemical potential by qualitative analysis.Results:The antioxidant activity of the extracts was found promising.The reducing power of this crude extract increase with the increase of concentration;IC_(50)values of DPPH scavenging activity was(140.00±0.86)μg/mL as compared to ascorbic acid[IC_(50)(130.00±0.76)μg/mL];Total phenol and total flavonoids content were(148.26±0.24)mg/mL and(163.06±0.56)mg/mL respecnvely.In cytotoxicity assay the LC_(50)values of the sample was(106.41±0.78)μg/mL where as for standard vincristin sulphate was(08.50±0.24)μg/mL as a positive control and the extract shows(12.8611.02)%clot lytic whereas standard streptokinase shows(30.86+0.44%clot lytic activity in thrombolytic assay.The phytochemical evaluation indicates the presence of chemical constituents including carbohydrates,alkaloids,saponins,glycosides,flavonoids.Conclusions:This study shows that the methanol extract of leaves of Adiantum philippense L.has bioactivitv but further compound isolation is necessary to confirm the activities of individual compounds.
文摘利用光学显微镜和扫描电子显微镜对产于广西的3种铁线蕨属植物的孢子形态进行了观察研究,详细描述了3种铁线蕨属植物即铁线蕨A d iantum cap illus-veneris L.、扇叶铁线蕨A.f labellu la tum L.和假鞭叶铁线蕨A.m a lesianum G hatak孢子的形态及表面纹饰特征,讨论了各种间的差异。
