This study examined the functioning of facilitation and suppression in visual selective attention in adults with Attention Deficit Hyperactivity Disorder (ADHD). Electrophysiological data were examined in control adul...This study examined the functioning of facilitation and suppression in visual selective attention in adults with Attention Deficit Hyperactivity Disorder (ADHD). Electrophysiological data were examined in control adults and adults with ADHD during a cued visual spatial selective attention task where in addition to directing attention, the cue probabilistically predicted the presence of a distractor. Late activity following the cue (ADAN) showed attention modulation for all participants. However, only ADHD participants showed additional significant distractor anticipation modulations. Stimulus related activity showed modulations of early visual processing (P1) as a function of attention and anticipated distractor presence for all participants suggesting functional facilitation and suppression. Findings suggest functional visual spatial selective attention in adults with ADHD.展开更多
BACKGROUND High risk of alcohol and drug use disorders in people with attentiondeficit/hyperactivity disorder(ADHD)calls for exploratory research of relationships with clinical features of ADHD.AIM To estimate prevale...BACKGROUND High risk of alcohol and drug use disorders in people with attentiondeficit/hyperactivity disorder(ADHD)calls for exploratory research of relationships with clinical features of ADHD.AIM To estimate prevalence of alcohol/drug use disorders and associations with ADHD symptom severity and emotional dysregulation,in adults with ADHD.METHODS This observational cross-sectional clinical study consisted of patients admitted to a private psychiatric outpatient clinic in Oslo,Norway(2014-2018).Five-hundred and fifty-eight eligible patients diagnosed with ADHD(Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM-5)criteria)agreed to participate.Alcohol and drug use disorders were diagnosed using the Mini International Neuropsychiatric Interview(MINI).Dependence and abuse were merged into“use”disorder as in MINI version 7.0/DSM-5.Questions were related both to lifetime and the past 12-mo.ADHD severity was assessed by the Adult ADHD Self Report Scale(ASRS).Subdivisions of the ASRS questionnaire as inattentive items and hyperactive/impulsivity items were recorded separately.Emotional dysregulation was assessed by the eight-item version of Barkley’s Current Behavior Scale-Self Report.RESULTS The 12-mo prevalence was 5.3%for alcohol use disorder and 13.7%for drug use disorder.The lifetime prevalence was 12.0%for alcohol use disorder and 27.7%for drug use disorder.Men had higher rates of both alcohol use disorder and drug use disorder compared to women.The prevalence of drug use disorder was more than twice that of alcohol use disorder for both sexes.The drugs most participants reported having used were(in descending order):Amphetamine(19.1%),cannabis(17.1%),cocaine or ecstasy(7.4%),benzodiazepines(7.4%),and heroin or other opioids(2.9%).Lifetime drug use disorder was significantly associated with both hyperactivity-impulsivity symptoms and emotional dysregulation symptom severity.Lifetime alcohol use disorder,on the other hand,was not significantly associated with ADHD symptoms or emotional dysregulation when adjusted for gender and age.CONCLUSION Patients with ADHD have a high lifetime prevalence of drug use disorder,which is associated with higher levels of hyperactivity-impulsivity symptoms and emotional dysregulation.展开更多
Objective: Alexithymia is increasingly recognized in a number of psychiatric disorders, but a possible relationship between alexithymia and adult attention-deficit/hyperactivity disorder (ADHD) has not been studied. I...Objective: Alexithymia is increasingly recognized in a number of psychiatric disorders, but a possible relationship between alexithymia and adult attention-deficit/hyperactivity disorder (ADHD) has not been studied. It is not known if psychostimulants decrease symptoms of both ADHD and alexithymia. This relationship is examined in a small naturalistic and longitudinal study. Participants: Ten consecutive stimulant-naive college students seek assessment and treatment for ADHD during the academic year. Method: Participants completed three self-report instruments quantifying ADHD symptomatology, alexithymia, and psychological mindedness prior to initiation of stimulant pharmacotherapy and after three and six months of medication treatment without formal psychotherapy. Results: ADHD symptoms decreased significantly from baseline to three months and remained low at six months. Decreases in alexithymia and increases in psychological mindedness changed more slowly, with significant differences occurring at six months compared to baseline. Conclusions: This study suggests that stimulant pharmacotherapy in college students with ADHD decreases ADHD symptoms and alexithymia while increasing psychological mindedness. These results have implications for untreated adult ADHD patients seeking psychotherapy.展开更多
Aims: This study was designed to verify the proportion of Japanese adults with pervasive developmental disorder (PDD) who met the diagnostic criteria (other than E) for attention-deficit/hyperactivity disorder (ADHD) ...Aims: This study was designed to verify the proportion of Japanese adults with pervasive developmental disorder (PDD) who met the diagnostic criteria (other than E) for attention-deficit/hyperactivity disorder (ADHD) in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). Furthermore, we examined to what extent adults with PDD think that they exhibit ADHD symptoms. Methods: We developed an original Japanese self-report questionnaire to determine the presence or absence of 18 symptoms from the diagnostic criteria for ADHD in the DSM-IV-TR. We administered the questionnaire to 64 adults with high-functioning PDD (45 men and 19 women) and 21 adults with ADHD (10 men and 11 women), aged 18 to 59 years, with a full-scale intelligence quotient ≥75. Target patients were evaluated for ADHD by their psychiatrists. Results: Twenty-nine (45.3%) adults with PDD also had ADHD. The percentage of these adults who had over six perceived inattention symptoms from the DSM-IV-TR was 96.6%. The percentage of these adults who had over six perceived hyperactivity-impulsivity symptoms was 65.5%. Thirty-five (55.6%) adults with PDD responded that they were aware of having ADHD symptoms at the level of the relevant diagnostic criteria. Conclusions: The present study is the first to examine the frequency of objective and perceived ADHD symptoms in adults with PDD in Japan. Our results show that both objective and perceived ADHD symptoms frequently appear in a large number of adults with PDD. This suggests that it is necessary to attend to concomitant ADHD symptoms in the medical care of adults with PDD.展开更多
采用VOSviewer软件分析2015-2019年Web of Science平台核心合集中成人注意力缺陷多动障碍文献,发现研究集中于症状表现、诊断及评量、病理与治疗,热点为成人注意力缺陷多动障碍与共病障碍的相互作用、儿童研究产生之诊断评量工具对于成...采用VOSviewer软件分析2015-2019年Web of Science平台核心合集中成人注意力缺陷多动障碍文献,发现研究集中于症状表现、诊断及评量、病理与治疗,热点为成人注意力缺陷多动障碍与共病障碍的相互作用、儿童研究产生之诊断评量工具对于成人的适用性、药物和心理治疗对成人的应用效果。未来研究可集中在探索该障碍在整个生命周期的变化、后果及干预,建立多维诊断评量模式,加强成人患者的治疗及效果等方面。展开更多
文摘This study examined the functioning of facilitation and suppression in visual selective attention in adults with Attention Deficit Hyperactivity Disorder (ADHD). Electrophysiological data were examined in control adults and adults with ADHD during a cued visual spatial selective attention task where in addition to directing attention, the cue probabilistically predicted the presence of a distractor. Late activity following the cue (ADAN) showed attention modulation for all participants. However, only ADHD participants showed additional significant distractor anticipation modulations. Stimulus related activity showed modulations of early visual processing (P1) as a function of attention and anticipated distractor presence for all participants suggesting functional facilitation and suppression. Findings suggest functional visual spatial selective attention in adults with ADHD.
文摘BACKGROUND High risk of alcohol and drug use disorders in people with attentiondeficit/hyperactivity disorder(ADHD)calls for exploratory research of relationships with clinical features of ADHD.AIM To estimate prevalence of alcohol/drug use disorders and associations with ADHD symptom severity and emotional dysregulation,in adults with ADHD.METHODS This observational cross-sectional clinical study consisted of patients admitted to a private psychiatric outpatient clinic in Oslo,Norway(2014-2018).Five-hundred and fifty-eight eligible patients diagnosed with ADHD(Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition(DSM-5)criteria)agreed to participate.Alcohol and drug use disorders were diagnosed using the Mini International Neuropsychiatric Interview(MINI).Dependence and abuse were merged into“use”disorder as in MINI version 7.0/DSM-5.Questions were related both to lifetime and the past 12-mo.ADHD severity was assessed by the Adult ADHD Self Report Scale(ASRS).Subdivisions of the ASRS questionnaire as inattentive items and hyperactive/impulsivity items were recorded separately.Emotional dysregulation was assessed by the eight-item version of Barkley’s Current Behavior Scale-Self Report.RESULTS The 12-mo prevalence was 5.3%for alcohol use disorder and 13.7%for drug use disorder.The lifetime prevalence was 12.0%for alcohol use disorder and 27.7%for drug use disorder.Men had higher rates of both alcohol use disorder and drug use disorder compared to women.The prevalence of drug use disorder was more than twice that of alcohol use disorder for both sexes.The drugs most participants reported having used were(in descending order):Amphetamine(19.1%),cannabis(17.1%),cocaine or ecstasy(7.4%),benzodiazepines(7.4%),and heroin or other opioids(2.9%).Lifetime drug use disorder was significantly associated with both hyperactivity-impulsivity symptoms and emotional dysregulation symptom severity.Lifetime alcohol use disorder,on the other hand,was not significantly associated with ADHD symptoms or emotional dysregulation when adjusted for gender and age.CONCLUSION Patients with ADHD have a high lifetime prevalence of drug use disorder,which is associated with higher levels of hyperactivity-impulsivity symptoms and emotional dysregulation.
文摘Objective: Alexithymia is increasingly recognized in a number of psychiatric disorders, but a possible relationship between alexithymia and adult attention-deficit/hyperactivity disorder (ADHD) has not been studied. It is not known if psychostimulants decrease symptoms of both ADHD and alexithymia. This relationship is examined in a small naturalistic and longitudinal study. Participants: Ten consecutive stimulant-naive college students seek assessment and treatment for ADHD during the academic year. Method: Participants completed three self-report instruments quantifying ADHD symptomatology, alexithymia, and psychological mindedness prior to initiation of stimulant pharmacotherapy and after three and six months of medication treatment without formal psychotherapy. Results: ADHD symptoms decreased significantly from baseline to three months and remained low at six months. Decreases in alexithymia and increases in psychological mindedness changed more slowly, with significant differences occurring at six months compared to baseline. Conclusions: This study suggests that stimulant pharmacotherapy in college students with ADHD decreases ADHD symptoms and alexithymia while increasing psychological mindedness. These results have implications for untreated adult ADHD patients seeking psychotherapy.
文摘Aims: This study was designed to verify the proportion of Japanese adults with pervasive developmental disorder (PDD) who met the diagnostic criteria (other than E) for attention-deficit/hyperactivity disorder (ADHD) in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). Furthermore, we examined to what extent adults with PDD think that they exhibit ADHD symptoms. Methods: We developed an original Japanese self-report questionnaire to determine the presence or absence of 18 symptoms from the diagnostic criteria for ADHD in the DSM-IV-TR. We administered the questionnaire to 64 adults with high-functioning PDD (45 men and 19 women) and 21 adults with ADHD (10 men and 11 women), aged 18 to 59 years, with a full-scale intelligence quotient ≥75. Target patients were evaluated for ADHD by their psychiatrists. Results: Twenty-nine (45.3%) adults with PDD also had ADHD. The percentage of these adults who had over six perceived inattention symptoms from the DSM-IV-TR was 96.6%. The percentage of these adults who had over six perceived hyperactivity-impulsivity symptoms was 65.5%. Thirty-five (55.6%) adults with PDD responded that they were aware of having ADHD symptoms at the level of the relevant diagnostic criteria. Conclusions: The present study is the first to examine the frequency of objective and perceived ADHD symptoms in adults with PDD in Japan. Our results show that both objective and perceived ADHD symptoms frequently appear in a large number of adults with PDD. This suggests that it is necessary to attend to concomitant ADHD symptoms in the medical care of adults with PDD.
文摘采用VOSviewer软件分析2015-2019年Web of Science平台核心合集中成人注意力缺陷多动障碍文献,发现研究集中于症状表现、诊断及评量、病理与治疗,热点为成人注意力缺陷多动障碍与共病障碍的相互作用、儿童研究产生之诊断评量工具对于成人的适用性、药物和心理治疗对成人的应用效果。未来研究可集中在探索该障碍在整个生命周期的变化、后果及干预,建立多维诊断评量模式,加强成人患者的治疗及效果等方面。
