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Multi-timescale Affinely Adjustable Robust Reactive Power Dispatch of Distribution Networks Integrated with High Penetration of PV 被引量:3
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作者 Peishuai Li Zaijun Wu +3 位作者 Cuo Zhang Yan Xu Zhaoyang Dong Minqiang Hu 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2023年第1期324-334,共11页
Photovoltaic(PV)power generation has highly penetrated in distribution networks,providing clean and sustainable energy.However,its uncertain and intermittent power outputs significantly impair network operation,leadin... Photovoltaic(PV)power generation has highly penetrated in distribution networks,providing clean and sustainable energy.However,its uncertain and intermittent power outputs significantly impair network operation,leading to unexpected power loss and voltage fluctuation.To address the uncertainties,this paper proposes a multi-timescale affinely adjustable robust reactive power dispatch(MTAAR-RPD)method to reduce the network power losses as well as alleviate voltage deviations and fluctuations.The MTAAR-RPD aims to coordinate on-load tap changers(OLTCs),capacitor banks(CBs),and PV inverters through a three-stage structure which covers multiple timescales of“hour-minute-second”.The first stage schedules CBs and OLTCs hourly while the second stage dispatches the base reactive power outputs of PV inverter every 15 min.The third stage affinely adjusts the inverter reactive power output based on an optimized Q-P droop controller in real time.The three stages are coordinately optimized by an affinely adjustable robust optimization method.A solution algorithm based on a cutting plane algorithm is developed to solve the optimization problem effectively.The proposed method is verified through theoretical analysis and numerical simulations. 展开更多
关键词 Multi-timescale photovoltaic(PV) reactive power dispatch UNCERTAINTY affinely adjustable robust optimization
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Alleviated photoinhibition on nitrification in the Indian Sector of the Southern Ocean 被引量:1
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作者 Lingfang Fan Min Chen +2 位作者 Zifei Yang Minfang Zheng Yusheng Qiu 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2024年第7期52-69,共18页
Nitrification,a central process in the marine nitrogen cycle,produces regenerated nitrate in the euphotic zone and emits N_(2)O,a potent greenhouse gas as a by-product.The regulatory mechanisms of nitrification in the... Nitrification,a central process in the marine nitrogen cycle,produces regenerated nitrate in the euphotic zone and emits N_(2)O,a potent greenhouse gas as a by-product.The regulatory mechanisms of nitrification in the Southern Ocean,which is a critical region for CO_(2)sequestration and radiative benefits,remain poorly understood.Here,we investigated the in situ and dark nitrification rates in the upper 500 m and conducted substrate kinetics experiments across the Indian Sector in the Cosmonaut and Cooperation seas in the late austral summer.Our findings indicate that light inhibition of nitrification decreases exponentially with depth,exhibiting a light threshold of 0.53%photosynthetically active radiation.A positive relationship between dark nitrification and apparent oxygen utilization suggests a dependence on substrate availability from primary production.Importantly,an increased NH_(4)^(+) supply can act as a buffer against photo-inhibitory damage.Globally,substrate affinity(α)increases with depth and transitions from light to dark,decreases with increasing ambient NH_(4)^(+)and exhibits a latitudinal distribution,reflecting substrate utilization strategies.We also reveal that upwelling in Circumpolar Deep Water(CDW)stimulates nitrification through the introduction of potentially higher iron and deep diverse nitrifying microorganisms with higherα.We conclude that although light is the primary limiting factor for nitrification in summer,coupling between substrate availability and CDW upwelling can overcome this limitation,thereby alleviating photoinhibition by up to 45%±5.3%. 展开更多
关键词 NITRIFICATION light inhibition substrate affinity circumpolar deep water(CDW)upwelling the Southern Ocean
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Analysis of affinely equivalent Boolean functions 被引量:5
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作者 MENG QingShu ZHANG HuanGuo +1 位作者 YANG Min WANG ZhangYi 《Science in China(Series F)》 2007年第3期299-306,共8页
By some basic transforms and invariant theory, we give two results: 1) an algorithm, which can be used to judge if two Boolean functions are affinely equivalent and to obtain the equivalence relationship if they are... By some basic transforms and invariant theory, we give two results: 1) an algorithm, which can be used to judge if two Boolean functions are affinely equivalent and to obtain the equivalence relationship if they are equivalent. This is useful in studying Boolean functions and in engineering. For example, we classify all 8-variable homogeneous bent functions of degree 3 into two classes; 2) Reed-Muller codes R(4,6)/R(1,6), R(3,7)/R(1,7) are classified efficiently. 展开更多
关键词 Boolean functions Reed-Muller code affinely equivalent INVARIANT
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多体非完全经典态的基于Affinity的关联测度
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作者 闫栋华 王银珠 《太原科技大学学报》 2024年第1期101-103,108,共4页
在量子信息理论中,量子关联是一种极其重要的物理资源。文章首先定义了多体非完全经典态基于Affinity的一种量子关联测度,它可以量化多体非完全经典态的关联程度;接下来证明了该关联测度满足量子关联度的一些必要物理性质,包括非负性、... 在量子信息理论中,量子关联是一种极其重要的物理资源。文章首先定义了多体非完全经典态基于Affinity的一种量子关联测度,它可以量化多体非完全经典态的关联程度;接下来证明了该关联测度满足量子关联度的一些必要物理性质,包括非负性、局部酉操作下的不变性、局部量子操作下的单调性、凸性以及连续性。 展开更多
关键词 多体复合系统 完全经典态 投影测量 量子关联度 AFFINITY
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New insights into the deposition of natural gas hydrate on pipeline surfaces:A molecular dynamics simulation study
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作者 Jun Zhang Hai-Qiang Fu +7 位作者 Mu-Zhi Guo Zhao Wang Li-Wen Li Qi Yin You-Guo Yan Wei Wei Wei-Feng Han Jie Zhong 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期694-704,共11页
Natural gas hydrate(NGH)can cause pipeline blockages during the transportation of oil and gas under high pressures and low temperatures.Reducing hydrate adhesion on pipelines is viewed as an efficient way to prevent N... Natural gas hydrate(NGH)can cause pipeline blockages during the transportation of oil and gas under high pressures and low temperatures.Reducing hydrate adhesion on pipelines is viewed as an efficient way to prevent NGH blockages.Previous studies suggested the water film can greatly increase hydrate adhesion in gas-dominant system.Herein,by performing the molecular dynamics simulations,we find in water-dominant system,the water film plays different roles in hydrate deposition on Fe and its corrosion surfaces.Specifically,due to the strong affinity of water on Fe surface,the deposited hydrate cannot convert the adsorbed water into hydrate,thus,a water film exists.As water affinities decrease(Fe>Fe_(2)O_(3)>FeO>Fe_(3)O_(4)),adsorbed water would convert to amorphous hydrate on Fe_(2)O_(3)and form the ordered hydrate on FeO and Fe_(3)O_(4)after hydrate deposition.While absorbed water film converts to amorphous or to hydrate,the adhesion strength of hydrate continuously increases(Fe<Fe_(2)O_(3)<FeO<Fe_(3)O_(4)).This is because the detachment of deposited hydrate prefers to occur at soft region of liquid layer,the process of which becomes harder as liquid layer vanishes.As a result,contrary to gas-dominant system,the water film plays the weakening roles on hydrate adhesion in water-dominant system.Overall,our results can help to better understand the hydrate deposition mechanisms on Fe and its corrosion surfaces and suggest hydrate deposition can be adjusted by changing water affinities on pipeline surfaces. 展开更多
关键词 DEPOSITION Natural gas hydrate Pipelines Water affinity Adhesion strength
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Diamond-based electron emission:Structure,properties and mechanisms
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作者 Liang-Xue Gu Kai Yang +10 位作者 Yan Teng Wei-Kang Zhao Geng-You Zhao Kang-Kang Fan Bo Feng Rong Zhang You-Dou Zheng Jian-Dong Ye Shun-Ming Zhu Kun Tang Shu-Lin Gu 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第9期165-177,共13页
Diamond has an ultrawide bandgap with excellent physical properties,such as high critical electric field,excellent thermal conductivity,high carrier mobility,etc.Diamond with a hydrogen-terminated(H-terminated)surface... Diamond has an ultrawide bandgap with excellent physical properties,such as high critical electric field,excellent thermal conductivity,high carrier mobility,etc.Diamond with a hydrogen-terminated(H-terminated)surface has a negative electron affinity(NEA)and can easily produce surface electrons from valence or trapped electrons via optical absorption,thermal heating energy or carrier transport in a PN junction.The NEA of the H-terminated surface enables surface electrons to emit with high efficiency into the vacuum without encountering additional barriers and promotes further development and application of diamond-based emitting devices.This article reviews the electron emission properties of H-terminated diamond surfaces exhibiting NEA characteristics.The electron emission is induced by different physical mechanisms.Recent advancements in electron-emitting devices based on diamond are also summarized.Finally,the current challenges and future development opportunities are discussed to further develop the relevant applications of diamond-based electronemitting devices. 展开更多
关键词 DIAMOND negative electron affinity(NEA) PN junction electron emission
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Accelerating Factor Xa inhibitor discovery with a de novo drug design pipeline
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作者 Yujing Zhao Qilei Liu +3 位作者 Jian Du Qingwei Meng Liang Sun Lei Zhang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第8期85-94,共10页
Small-molecule drugs are essential for maintaining human health. The objective of this study is to identify a molecule that can inhibit the Factor Xa protein and be easily procured. An optimization-based de novo drug ... Small-molecule drugs are essential for maintaining human health. The objective of this study is to identify a molecule that can inhibit the Factor Xa protein and be easily procured. An optimization-based de novo drug design framework, Drug CAMD, that integrates a deep learning model with a mixed-integer nonlinear programming model is used for designing drug candidates. Within this framework, a virtual chemical library is specifically tailored to inhibit Factor Xa. To further filter and narrow down the lead compounds from the designed compounds, comprehensive approaches involving molecular docking,binding pose metadynamics(BPMD), binding free energy calculations, and enzyme activity inhibition analysis are utilized. To maximize efficiency in terms of time and resources, molecules for in vitro activity testing are initially selected from commercially available portions of customized virtual chemical libraries. In vitro studies assessing inhibitor activities have confirmed that the compound EN300-331859shows potential Factor Xa inhibition, with an IC_(50)value of 34.57 μmol·L^(-1). Through in silico molecular docking and BPMD, the most plausible binding pose for the EN300-331859-Factor Xa complex are identified. The estimated binding free energy values correlate well with the results obtained from biological assays. Consequently, EN300-331859 is identified as a novel and effective sub-micromolar inhibitor of Factor Xa. 展开更多
关键词 Chemical product design Mathematical programming method Deep learning Binding affinity Factor Xa inhibitor
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Fixed-Time Antidisturbance Consensus Tracking for Nonlinear Multiagent Systems With Matching and Mismatching Disturbances
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作者 Xiangmin Tan Chunyan Hu +3 位作者 Guanzhen Cao Qinglai Wei Wei Li Bo Han 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第6期1410-1423,共14页
In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is prop... In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is proposed,which consists of a distributed fixed-time observer,a fixed-time disturbance observer,a nonsmooth antidisturbance backstepping controller,and the fixed-time stability analysis is conducted by using the Lyapunov theory correspondingly.This paper includes three main improvements.First,a distributed fixed-time observer is developed for each follower to obtain an estimate of the leader’s output by utilizing the topology of the communication network.Second,a fixed-time disturbance observer is given to estimate the lumped disturbances for feedforward compensation.Finally,a nonsmooth antidisturbance backstepping tracking controller with feedforward compensation for lumped disturbances is designed.In order to mitigate the“explosion of complexity”in the tradi-tional backstepping approach,we have implemented a modified nonsmooth command filter to enhance the performance of the closed-loop system.The simulation results show that the pro-posed method is effective. 展开更多
关键词 Antidisturbance BACKSTEPPING consensus tracking fixed-time stability multiagent system(MASs) strict feedback affine nonlinear systems.
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An Algorithm for Short-Circuit Current Interval in Distribution Networks with Inverter Type Distributed Generation Based on Affine Arithmetic
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作者 Yan Zhang Bowen Du +3 位作者 Benren Pan GuannanWang Guoqiang Xie Tong Jiang 《Energy Engineering》 EI 2024年第7期1903-1920,共18页
During faults in a distribution network,the output power of a distributed generation(DG)may be uncertain.Moreover,the output currents of distributed power sources are also affected by the output power,resulting in unc... During faults in a distribution network,the output power of a distributed generation(DG)may be uncertain.Moreover,the output currents of distributed power sources are also affected by the output power,resulting in uncertainties in the calculation of the short-circuit current at the time of a fault.Additionally,the impacts of such uncertainties around short-circuit currents will increase with the increase of distributed power sources.Thus,it is very important to develop a method for calculating the short-circuit current while considering the uncertainties in a distribution network.In this study,an affine arithmetic algorithm for calculating short-circuit current intervals in distribution networks with distributed power sources while considering power fluctuations is presented.The proposed algorithm includes two stages.In the first stage,normal operations are considered to establish a conservative interval affine optimization model of injection currents in distributed power sources.Constrained by the fluctuation range of distributed generation power at the moment of fault occurrence,the model can then be used to solve for the fluctuation range of injected current amplitudes in distributed power sources.The second stage is implemented after a malfunction occurs.In this stage,an affine optimization model is first established.This model is developed to characterizes the short-circuit current interval of a transmission line,and is constrained by the fluctuation range of the injected current amplitude of DG during normal operations.Finally,the range of the short-circuit current amplitudes of distribution network lines after a short-circuit fault occurs is predicted.The algorithm proposed in this article obtains an interval range containing accurate results through interval operation.Compared with traditional point value calculation methods,interval calculation methods can provide more reliable analysis and calculation results.The range of short-circuit current amplitude obtained by this algorithm is slightly larger than those obtained using the Monte Carlo algorithm and the Latin hypercube sampling algorithm.Therefore,the proposed algorithm has good suitability and does not require iterative calculations,resulting in a significant improvement in computational speed compared to the Monte Carlo algorithm and the Latin hypercube sampling algorithm.Furthermore,the proposed algorithm can provide more reliable analysis and calculation results,improving the safety and stability of power systems. 展开更多
关键词 Short circuit calculation inverter type distributed power supplies affine arithmetic distribution network
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在复二维仿射锥上的完备余齐性一Kahler度量
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作者 关庄丹 梁梦翔 《Chinese Quarterly Journal of Mathematics》 2024年第2期200-220,共21页
In this paper,we revisit the Kahler structures on the affine quadrics M1={z_(1)^(2)+z_(2)^(2)+z_(3)^(2)=1}in the paper by Bo Yang and Fang-Yang Zheng.We found that the Kahler structures on the complex surface are more... In this paper,we revisit the Kahler structures on the affine quadrics M1={z_(1)^(2)+z_(2)^(2)+z_(3)^(2)=1}in the paper by Bo Yang and Fang-Yang Zheng.We found that the Kahler structures on the complex surface are more complicated than what they have thought.We shall also give some detail calculations and found that our results fit quite well with earlier papers of the first author,one of them with X.X.Chen. 展开更多
关键词 Affine quadrics Complex structure Kahler metrics Cohomogeneity one action
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A Remark on the Affine Coordinates for KdV Tau-Functions
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作者 FU Zhi-peng 《Chinese Quarterly Journal of Mathematics》 2024年第3期324-330,共7页
We give a proof of an explicit formula for affine coodinates of points in the Sato’s infinite Grassmannian corresponding to tau-functions for the KdV hierarchy.
关键词 Sato’s infinite Grassmannian KdV hierarchy Affine coordinates
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Effect of Freeze-Thaw and Urea in Solubility of GPC3-Csub Protein Expressed in Escherichia coli
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作者 Xuan-Truc Chu-Dao Kim-Tuyen Huynh-Dam +2 位作者 Dang-Thuc Ngo-Luong Quang-Luan Le Thanh-Thao Vo-Nguyen 《Journal of Biosciences and Medicines》 2024年第4期288-297,共10页
Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential ... Glypican-3 is a protein encoded by the Glypican-3 gene located on human X chromosome (Xq26), composed of two subunits, a 40 kDa N-terminal subunit, and a 30 kDa C-terminal subunit. Glypican-3 is a currently potential target molecule for liver cancer treatments because of its over-expression and growth effects on hepatocellular carcinoma (HCC). This study examined the expression and purification of a C-terminal subunit of Glypican-3 protein (GPC3-Csub) due to its application in both diagnosis and therapy for hepatocellular carcinoma. The gene encoding for GPC3-Csub was successfully cloned into plasmid pET28a fused with an affinity tag composed of six consecutive histidine residues (His-tag). Recombinant protein GPC3-Csub was expressed in Escherichia coli BL21 (DE3) in the condition of adding 3% ethanol with IPTG induction. GPC3-Csub was extracted using repeated freeze-thaw cycles with lysozyme, and inclusion bodies were solubilized by 8M Urea, SDS 10% in pH 12. His-tag fused GPC3-Csub proteins allowed it to be purified by affinity chromatography method using the Nickel-nitrilotriacetic acid (Ni-NTA) column. High expression of GPC3-Csub was confirmed by Coomassie staining and western-blot. GPC3-Csub could be isolated with a Ni-NTA column and have a purity of about 90%. 展开更多
关键词 GLYPICAN-3 Affinity Chromatography Inclusion Body Liver Cancer
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Strategies for Enhancing the Affinity of College Ideological and Political Course Teachers
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作者 WANG Na 《Cultural and Religious Studies》 2024年第2期113-117,共5页
This article aims to explore effective ways to enhance the affinity of ideological and political course teachers in universities.By analyzing the connotation of affinity,the factors that affect the affinity of ideolog... This article aims to explore effective ways to enhance the affinity of ideological and political course teachers in universities.By analyzing the connotation of affinity,the factors that affect the affinity of ideological and political course teachers are analyzed,and corresponding improvement strategies are proposed.Research suggests that strengthening the construction of teacher ethics and conduct,improving teaching skills,enhancing emotional engagement,and enhancing practical training are key paths to enhance the affinity of ideological and political course teachers.The implementation of these paths will help improve the teaching quality and effectiveness of ideological and political courses,and promote the comprehensive development of students. 展开更多
关键词 ideological and political courses in universities teacher affinity improvement path teaching quality
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Affinely Prime Dynamical Systems(Dedicated to Professor Haim Brezis on the occasion of his 70th birthday)
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作者 Hillel FURSTENBERG Eli GLASNER Benjamin WEISS 《Chinese Annals of Mathematics,Series B》 SCIE CSCD 2017年第2期413-424,共12页
This paper deals with representations of groups by "affine" automorphisms of compact, convex spaces, with special focus on "irreducible" representations: equivalently"minimal" actions. Wh... This paper deals with representations of groups by "affine" automorphisms of compact, convex spaces, with special focus on "irreducible" representations: equivalently"minimal" actions. When the group in question is P SL(2, R), the authors exhibit a oneone correspondence between bounded harmonic functions on the upper half-plane and a certain class of irreducible representations. This analysis shows that, surprisingly, all these representations are equivalent. In fact, it is found that all irreducible affine representations of this group are equivalent. The key to this is a property called "linear Stone-Weierstrass"for group actions on compact spaces. If it holds for the "universal strongly proximal space"of the group(to be defined), then the induced action on the space of probability measures on this space is the unique irreducible affine representation of the group. 展开更多
关键词 Irreducible affine dynamical systems affinely prime Strong proximality Mbius transformations Harmonic functions
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Heteroclinic Cycles in a Class of 3-Dimensional Piecewise Affine Systems
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作者 Minghao Liu Ruimin Liu 《Journal of Applied Mathematics and Physics》 2024年第2期488-508,共21页
This paper explores the existence of heteroclinic cycles and corresponding chaotic dynamics in a class of 3-dimensional two-zone piecewise affine systems. Moreover, the heteroclinic cycles connect two saddle foci and ... This paper explores the existence of heteroclinic cycles and corresponding chaotic dynamics in a class of 3-dimensional two-zone piecewise affine systems. Moreover, the heteroclinic cycles connect two saddle foci and intersect the switching manifold at two points and the switching manifold is composed of two perpendicular planes. 展开更多
关键词 Piecewise Affine System Heteroclinic Cycle Chaotic Invariant Set
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Recent progress in targeting the sialylated glycan-SIGLEC axis in cancer immunotherapy 被引量:3
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作者 Yingyan Yu Wenjie Peng 《Cancer Biology & Medicine》 SCIE CAS CSCD 2023年第5期369-384,共16页
Malignant tumors are complex structures composed of cancer cells and tumor microenvironmental cells.In this complex structure,cells cross-talk and interact,thus jointly promoting cancer development and metastasis.Rece... Malignant tumors are complex structures composed of cancer cells and tumor microenvironmental cells.In this complex structure,cells cross-talk and interact,thus jointly promoting cancer development and metastasis.Recently,immunoregulatory molecule-based cancer immunotherapy has greatly improved treatment efficacy for solid cancers,thus enabling some patients to achieve persistent responses or cure.However,owing to the development of drug-resistance and the low response rate,immunotherapy against the available targets PD-1/PD-L1 or CTLA-4 has limited benefits.Although combination therapies have been proposed to enhance the response rate,severe adverse effects are observed.Thus,alternative immune checkpoints must be identified.The SIGLECs are a family of immunoregulatory receptors(known as glyco-immune checkpoints)discovered in recent years.This review systematically describes the molecular characteristics of the SIGLECs,and discusses recent progress in areas including synthetic ligands,monoclonal antibody inhibitors,and Chimeric antigen receptor T(CAR-T)cells,with a focus on available strategies for blocking the sialylated glycan-SIGLEC axis.Targeting glyco-immune checkpoints can expand the scope of immune checkpoints and provide multiple options for new drug development. 展开更多
关键词 SIGLEC sialylated glycan glyco-immune checkpoint high affinity SIGLEC-ligands anti-SIGLEC antibodies
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Effective anti-inflammatory phenolic compounds from dandelion:identification and mechanistic insights using UHPLC-ESI-MS/MS,fluorescence quenching and anisotropy,molecular docking and dynamics simulation 被引量:1
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作者 Hui Zou Tingting Ben +2 位作者 Ping Wu Geoffrey I.N.Waterhouse Yilun Chen 《Food Science and Human Wellness》 SCIE CSCD 2023年第6期2184-2194,共11页
This novel study identifi es the effective anti-inflammatory phenolic compounds in dandelion and provides mechanistic insights into their interactions with receptor proteins(toll-like receptor 4,TLR4;co-receptor myelo... This novel study identifi es the effective anti-inflammatory phenolic compounds in dandelion and provides mechanistic insights into their interactions with receptor proteins(toll-like receptor 4,TLR4;co-receptor myeloid differentiation protein-2,MD-2)using UHPLC-ESI-MS/MS,lipopolysaccharide(LPS)-stimulated THP-1 cell line,fluorescence quenching and anisotropy,molecular docking(single ligand and multi-ligand docking)and molecular dynamics simulation.A 50%aqueous methanol extract had a greater anti-inflammatory effect and higher chicoric acid content,compared with the 100%water and 100%methanol extracts.Chicoric acid,chlorogenic acid,methylophiopogonone A,caffeic acid,gallic acid monohydrate and 4’-O-demethylbroussonin A had relatively high binding energies and contents in all extracts.Chicoric acid competed with chlorogenic acid,4’-O-demethylbroussonin A and quercetin for MD-2.Among dandelion’s phenolics,chicoric acid most effectively hindered TLR4-MD-2 complex formation,with a quenching constant of 0.62×10^(6) L/mol for MD-2 or TLR4 at 320 K,and binding energies of-6.87 and-5.97 kcal/mol,respectively,for MD-2 and TLR4. 展开更多
关键词 Dandelion extracts Phenolic compounds binding affinity TLR4-MD-2 antagonist Anti-inflammatory agent
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多体k不可分量子态基于Affinity的纠缠测度
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作者 杨丽丽 王银珠 《太原科技大学学报》 2023年第6期567-570,共4页
量子纠缠是一种重要的物理资源,已被广泛应用于量子信息及量子计算的许多领域中。提出了一种多体复合系统量子态相对于k体分划的基于Affinity的纠缠测度,并证明了其满足纠缠测度的必要物理性质。
关键词 多体量子系统 k可分性 AFFINITY 纠缠测度
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CONFORMALLY FLAT AFFINE HYPERSURFACES WITH SEMI-PARALLEL CUBIC FORM
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作者 徐辉阳 李策策 《Acta Mathematica Scientia》 SCIE CSCD 2023年第6期2413-2429,共17页
In this paper,we study locally strongly convex affine hypersurfaces with the vanishing Weyl curvature tensor and semi-parallel cubic form relative to the Levi-Civita connection of the affine metric.As a main result,we... In this paper,we study locally strongly convex affine hypersurfaces with the vanishing Weyl curvature tensor and semi-parallel cubic form relative to the Levi-Civita connection of the affine metric.As a main result,we classify these hypersurfaces as not being of a flat affine metric.In particular,2 and 3-dimensional locally strongly convex affine hypersurfaces with semi-parallel cubic forms are completely determined. 展开更多
关键词 affine hypersurface semi-parallel cubic form Levi-Civita connection conformally flat warped product
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UV/Vis-based process analytical technology to improve monoclonal antibody and host cell protein separation
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作者 Yu Kiat Lin Yan-Na Sun +3 位作者 Yu Fan Hui Yi Leong Dong-Qiang Lin Shan-Jing Yao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第3期230-235,共6页
Process analytical technology(PAT) is gaining more interest in the biomanufacturing industry because of its potential to improve operational control and compliance through real-time quality assurance.Currently, biopha... Process analytical technology(PAT) is gaining more interest in the biomanufacturing industry because of its potential to improve operational control and compliance through real-time quality assurance.Currently, biopharmaceutical producers mainly monitor chromatographic processes with ultraviolet/visible(UV/Vis) absorbance. However, this measurement has a very limited correlation with purity and quantity. The current study aims to determine the concentration of monoclonal antibody(mAb) and host cell proteins(HCPs) using a build-in UV/Vis monitoring during Protein A affinity chromatography and to optimize the separation conditions for high purity of mAb and minimizing the HCPs content. The eluate was analyzed through in-line UV/Vis at 280 and 410 nm, representing mAb and HCPs concentration,respectively. Each 0.1 column volume(CV) fraction of UV/Vis chromatogram peak area were calculated,and different separation conditions were then compared. The optimum conditions of mAb separation were found as 12 CV loading, elution at pH 3.5, and starting the collection at 0.5 CV point, resulting in high m Ab recovery of 95.92% and additional removal of 49.98% of HCP comparing with whole elution pool. This study concluded that UV/Vis-based in-line monitoring at 280 and 410 nm showed a high potential to optimize and real-time control Protein A affinity chromatography for mAb purification from HCPs. 展开更多
关键词 Affinity chromatography Host cell protein Monoclonal antibody Process analytical technology SPECTROSCOPY
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