A three-coordinate Ag（I） complex, [Ag（Mepzpy）（PAr3）]BF4·H2O（1, Mepzpy = 3-methyl-1-（2-pyridyl）pyrazole, PAr3 = tri（o-tolyl）phosphine）, was synthesized from the reaction of Ag（CH3CN）4BF4, PAr3 and Me...A three-coordinate Ag（I） complex, [Ag（Mepzpy）（PAr3）]BF4·H2O（1, Mepzpy = 3-methyl-1-（2-pyridyl）pyrazole, PAr3 = tri（o-tolyl）phosphine）, was synthesized from the reaction of Ag（CH3CN）4BF4, PAr3 and Mepzpy in CH3 CN at room temperature. The compound was characterized by UV-vis, NMR and X-ray single-crystal structure analysis. It crystallizes in triclinic space group P1 with a = 10.2251（5）, b = 10.6014（5）, c = 15.7012（5） A, α = 92.963（3）, β = 92.641（3）, γ = 114.647（4）°, V = 1540.6（1）A 3, Z = 2, Mr = 676.24, Dc = 1.458 g/cm3, F（000） = 688, μ = 6.187 mm^-1, GOOF = 1.038, the final R = 0.0530 and wR = 0.1493 for 6371 observed reflections with I 〉 2σ（I）. Compound 1 is ionic. It is composed of a BF4- anion and a [Ag（Mepzpy）（PAr3）]＋ cation. The Ag（I） ion adopts a distorted trigonal pyramidal coordination geometry defined by two nitrogen atoms and a phosphorous atom. The complex emits blue luminescence with maximum peaks at 470 nm in solid state at room temperature.展开更多
Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together...Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together adjacent sulci. This follicle-sulcus-crack complex (FSCC) is exacerbated by dehydration. Purpose: Although dehydration is associated with facial skin aging, FSCC’s implications in facial skin aging remain unresolved. Method: We measured facial skin parameters in 1999 and 2010 in 108 Japanese women, and in 2006 and 2016 in 182 Chinese women. We addressed whether expansion of FSCC is associated with other skin aging parameters. We also examined whether skin moisturizer can reverse the expanded FSCC. Results: In both clinical studies, FSCC severity as well as wrinkles, spots, and roughness significantly deteriorated with age. Notably, FSCC significantly increased as early as in subjects in their 20s, whereas wrinkles, spots, and roughness became conspicuous in those in their 40s or older. Moreover, subjects with more severe FSCC in the initial measurement exhibited significantly worse wrinkles, spots, and roughness in the second measurement a decade later. Dehydration was significantly correlated with expanded FSCC. Furthermore, FSCC expansion was reversed after appropriate moisturization by daily application of Galactomyces ferment filtrate (GFF)-containing skincare product (SK-II Skin Power Cream) for 4 weeks in 37 women. Conclusion: The expanded FSCC is likely to be an early indicator of facial skin aging. Appropriate moisturization may reduce FSCC formation and decelerate facial skin aging.展开更多
A new dinuclear complex, [Ag（L）（CH3CN）]2（ClO4）2·2H2O（L=2,3-di-2-pyridylquinoxaline）, was prepared and characterized by elemental analyses, IR spectroscopy, and single-crystal X-ray diffraction analyses. T...A new dinuclear complex, [Ag（L）（CH3CN）]2（ClO4）2·2H2O（L=2,3-di-2-pyridylquinoxaline）, was prepared and characterized by elemental analyses, IR spectroscopy, and single-crystal X-ray diffraction analyses. The interaction of the complex with calf thymus DNA（CT-DNA） was investigated by absorption, fluorescence spectroscopies, and viscosity measurement. The results suggested that the complex was bound to DNA via an intercalative mode. The intrinsic binding constant value Kb was found to be approximately 1.48×10^3 L·mol^-1. Moreover, the Ag（I） complex could cleave the plasmid pUC19 DNA from the supercoiled Form Ⅰto the nicked FormⅡ under irradiation at 365 nm.展开更多
Five silver(Ⅰ) complexes with Schiff bases obtained from salicylaldehyde and five corresponding α-amino acids were synthesized. The complexes were characterized by elemental analysis, IR and 1H NMR measurements. Bio...Five silver(Ⅰ) complexes with Schiff bases obtained from salicylaldehyde and five corresponding α-amino acids were synthesized. The complexes were characterized by elemental analysis, IR and 1H NMR measurements. Bioactivity tests showed that the complexes inhibited the cucumber mosaic virus. Among them the best effective was glycine salicylaldehyde Schiffbase Ag(Ⅰ), which gave the effective level up to 74.7% towards CMV in dosage of 400 mg/L(in case of phaseolus vulgarisl inoculation).展开更多
基金supported by the National Natural Science Foundation of China(51172232)
文摘A three-coordinate Ag（I） complex, [Ag（Mepzpy）（PAr3）]BF4·H2O（1, Mepzpy = 3-methyl-1-（2-pyridyl）pyrazole, PAr3 = tri（o-tolyl）phosphine）, was synthesized from the reaction of Ag（CH3CN）4BF4, PAr3 and Mepzpy in CH3 CN at room temperature. The compound was characterized by UV-vis, NMR and X-ray single-crystal structure analysis. It crystallizes in triclinic space group P1 with a = 10.2251（5）, b = 10.6014（5）, c = 15.7012（5） A, α = 92.963（3）, β = 92.641（3）, γ = 114.647（4）°, V = 1540.6（1）A 3, Z = 2, Mr = 676.24, Dc = 1.458 g/cm3, F（000） = 688, μ = 6.187 mm^-1, GOOF = 1.038, the final R = 0.0530 and wR = 0.1493 for 6371 observed reflections with I 〉 2σ（I）. Compound 1 is ionic. It is composed of a BF4- anion and a [Ag（Mepzpy）（PAr3）]＋ cation. The Ag（I） ion adopts a distorted trigonal pyramidal coordination geometry defined by two nitrogen atoms and a phosphorous atom. The complex emits blue luminescence with maximum peaks at 470 nm in solid state at room temperature.
文摘Background: Wrinkles, pigmented spots, and roughness are representative parameters reflecting facial skin aging. Sulci cutis connecting to follicular orifices frequently form perifollicular cracks, which join together adjacent sulci. This follicle-sulcus-crack complex (FSCC) is exacerbated by dehydration. Purpose: Although dehydration is associated with facial skin aging, FSCC’s implications in facial skin aging remain unresolved. Method: We measured facial skin parameters in 1999 and 2010 in 108 Japanese women, and in 2006 and 2016 in 182 Chinese women. We addressed whether expansion of FSCC is associated with other skin aging parameters. We also examined whether skin moisturizer can reverse the expanded FSCC. Results: In both clinical studies, FSCC severity as well as wrinkles, spots, and roughness significantly deteriorated with age. Notably, FSCC significantly increased as early as in subjects in their 20s, whereas wrinkles, spots, and roughness became conspicuous in those in their 40s or older. Moreover, subjects with more severe FSCC in the initial measurement exhibited significantly worse wrinkles, spots, and roughness in the second measurement a decade later. Dehydration was significantly correlated with expanded FSCC. Furthermore, FSCC expansion was reversed after appropriate moisturization by daily application of Galactomyces ferment filtrate (GFF)-containing skincare product (SK-II Skin Power Cream) for 4 weeks in 37 women. Conclusion: The expanded FSCC is likely to be an early indicator of facial skin aging. Appropriate moisturization may reduce FSCC formation and decelerate facial skin aging.
基金Natural Science Foundation of Liaoning Province, China(No.20061073)Education Committee Foundation of Liaoning Province, China(No.22004F023)
文摘A new dinuclear complex, [Ag（L）（CH3CN）]2（ClO4）2·2H2O（L=2,3-di-2-pyridylquinoxaline）, was prepared and characterized by elemental analyses, IR spectroscopy, and single-crystal X-ray diffraction analyses. The interaction of the complex with calf thymus DNA（CT-DNA） was investigated by absorption, fluorescence spectroscopies, and viscosity measurement. The results suggested that the complex was bound to DNA via an intercalative mode. The intrinsic binding constant value Kb was found to be approximately 1.48×10^3 L·mol^-1. Moreover, the Ag（I） complex could cleave the plasmid pUC19 DNA from the supercoiled Form Ⅰto the nicked FormⅡ under irradiation at 365 nm.
文摘Five silver(Ⅰ) complexes with Schiff bases obtained from salicylaldehyde and five corresponding α-amino acids were synthesized. The complexes were characterized by elemental analysis, IR and 1H NMR measurements. Bioactivity tests showed that the complexes inhibited the cucumber mosaic virus. Among them the best effective was glycine salicylaldehyde Schiffbase Ag(Ⅰ), which gave the effective level up to 74.7% towards CMV in dosage of 400 mg/L(in case of phaseolus vulgarisl inoculation).
