The purpose of this research is to implement an IT-based education program in order to promote cervical cancer screenings for women aged 20 - 29 years, as well as to examine the results of said program. This is a long...The purpose of this research is to implement an IT-based education program in order to promote cervical cancer screenings for women aged 20 - 29 years, as well as to examine the results of said program. This is a longitudinal/comparative study of two groups, one for which the program was implemented (the intervention group), and the other for which it was not (the control group). The program consisted of attending a health lecture and encouragement to be screened one month, six months, and one year later sent through IT-based methods. The target was unmarried women aged 20 - 29 who had neither previously given birth nor had been screened for cervical cancer in a period one year prior. They were divided into two groups, the intervention group (n = 142) and control group (n = 145). The effectiveness of the program was assessed via an initial survey and further surveys six months and one year later. Results were based on the Japanese version of the Health Belief Model Scale for Cervical Cancer and the Pap Smear Test (HBMSCCPST), knowledge scores in the categories of Healthy Lifestyles, Cervical Cancer, Cervical Cancer Screening, and screening behavior. A two-way ANOVA of the HBMSCCPST subscales and knowledge scores in the initial, six-month, and one-year surveys was performed, showing interaction in Cervical Cancer (p = 0.00). Main effects were observed in Cervical Cancer Screening (p = 0.00) and Healthy Lifestyles (p = 0.00). Regarding the amount of change from the initial survey, knowledge scores in the Cervical Cancer (p = 0.027) and Cervical Cancer Screening (p = 0.016) categories were significantly higher in the intervention group than in the control group. There was no significant difference in cervical cancer screening rates (p = 0.26) between the two groups. However, a small-degree effect size was observed for Benefits, Seriousness, and Susceptibility subscales in both examinees and non-examinees. Although the educational program of this study was effective in improving the knowledge of women in their twenties, there was little improvement in HBMSCCPST and it did not lead to the promotion of cervical cancer screening. In order to raise interest in cervical cancer screening, it is necessary to consider useful content to guide women to consult with healthcare professionals, a long-term population approach, and organizational structure of consultation.展开更多
目的研究五加Acanthopanax gracilistylus var. gracilistylus地上部分的化学成分。方法采用硅胶、Sephadex LH-20凝胶、ODS等柱色谱方法及制备液相色谱技术分离纯化,运用核磁共振波谱、质谱等谱学技术结合理化性质鉴定化合物结构,采用...目的研究五加Acanthopanax gracilistylus var. gracilistylus地上部分的化学成分。方法采用硅胶、Sephadex LH-20凝胶、ODS等柱色谱方法及制备液相色谱技术分离纯化,运用核磁共振波谱、质谱等谱学技术结合理化性质鉴定化合物结构,采用MTT法研究化合物的细胞毒活性。结果从五加地上部分70%乙醇提取物中分离得到1个新的降羽扇豆烷型三萜3α,4α,11α-三羟基-23-降羽扇豆-20(29)-烯-28-酸(1)和4个已知羽扇豆三萜3α,11α-二羟基羽扇豆-20(29)-烯-28-酸(2)、23-氧-3α,11α-二羟基羽扇豆-20(29)-烯-28-酸(3)、23-氧-3α-羟基羽扇豆-20(29)-烯-28-酸(4)和3α-羟基羽扇豆-20(29)-烯-23,28-二酸(5)。结论化合物1为新化合物,命名为新印象酸。活性实验结果表明化合物1对人骨肉瘤143B细胞无显著细胞毒活性。展开更多
文摘The purpose of this research is to implement an IT-based education program in order to promote cervical cancer screenings for women aged 20 - 29 years, as well as to examine the results of said program. This is a longitudinal/comparative study of two groups, one for which the program was implemented (the intervention group), and the other for which it was not (the control group). The program consisted of attending a health lecture and encouragement to be screened one month, six months, and one year later sent through IT-based methods. The target was unmarried women aged 20 - 29 who had neither previously given birth nor had been screened for cervical cancer in a period one year prior. They were divided into two groups, the intervention group (n = 142) and control group (n = 145). The effectiveness of the program was assessed via an initial survey and further surveys six months and one year later. Results were based on the Japanese version of the Health Belief Model Scale for Cervical Cancer and the Pap Smear Test (HBMSCCPST), knowledge scores in the categories of Healthy Lifestyles, Cervical Cancer, Cervical Cancer Screening, and screening behavior. A two-way ANOVA of the HBMSCCPST subscales and knowledge scores in the initial, six-month, and one-year surveys was performed, showing interaction in Cervical Cancer (p = 0.00). Main effects were observed in Cervical Cancer Screening (p = 0.00) and Healthy Lifestyles (p = 0.00). Regarding the amount of change from the initial survey, knowledge scores in the Cervical Cancer (p = 0.027) and Cervical Cancer Screening (p = 0.016) categories were significantly higher in the intervention group than in the control group. There was no significant difference in cervical cancer screening rates (p = 0.26) between the two groups. However, a small-degree effect size was observed for Benefits, Seriousness, and Susceptibility subscales in both examinees and non-examinees. Although the educational program of this study was effective in improving the knowledge of women in their twenties, there was little improvement in HBMSCCPST and it did not lead to the promotion of cervical cancer screening. In order to raise interest in cervical cancer screening, it is necessary to consider useful content to guide women to consult with healthcare professionals, a long-term population approach, and organizational structure of consultation.
文摘目的研究五加Acanthopanax gracilistylus var. gracilistylus地上部分的化学成分。方法采用硅胶、Sephadex LH-20凝胶、ODS等柱色谱方法及制备液相色谱技术分离纯化,运用核磁共振波谱、质谱等谱学技术结合理化性质鉴定化合物结构,采用MTT法研究化合物的细胞毒活性。结果从五加地上部分70%乙醇提取物中分离得到1个新的降羽扇豆烷型三萜3α,4α,11α-三羟基-23-降羽扇豆-20(29)-烯-28-酸(1)和4个已知羽扇豆三萜3α,11α-二羟基羽扇豆-20(29)-烯-28-酸(2)、23-氧-3α,11α-二羟基羽扇豆-20(29)-烯-28-酸(3)、23-氧-3α-羟基羽扇豆-20(29)-烯-28-酸(4)和3α-羟基羽扇豆-20(29)-烯-23,28-二酸(5)。结论化合物1为新化合物,命名为新印象酸。活性实验结果表明化合物1对人骨肉瘤143B细胞无显著细胞毒活性。
