Increased Prevalence of Severe Rheumatic Heart Disease Requiring Early Valve Replacement Surgery and Fragmented Germ Cells

Background: Patients requiring valve replacement at a younger age, for rheumatic heart disease was apparently increasing after the new age practice of contraception. Methods: In 2012, data of patients referred to tertiary care hospital from two cardiology screening camps conducted in the community, were analyzed for the severity of presentation of rheumatic heart disease and associated contraception status by dividing into the three age groups—20 - 35 years, 36 - 50 years, >51 years;~400 patients attended the camps;31 female and 2 male patients were referred to the tertiary care hospital for further evaluation and categorized treatment, including valve replacement surgeries;among the 33 referred patients, belonging to the three age groups, the data were analyzed for [if any] correlation of contraception status with severe rheumatic heart disease. 8 randomly chosen males, of the 3 age groups, from a different community, whose life partners had undergone sterilization, were assessed for their serum testosterone levels. Results: Among 20 - 35 years, 7 female patients with contraception required valve replacement surgeries [p 51 years, 3 female and 2 male patients without contraception received medical treatment only

<i>“Withered Tree” Concept Host</i>, Achieved by Global Contraception and Abortion, Secondary to Fragmented Germ Cells, Agonizingly Reduced Endogenous Estrogen/Androgen, Defaulted Genomic Repertoire, Deranged Cell Metabolism, Metabolic Syndrome, <i>Result in Failure of Pharmacological Therapeutics with Advanced Technologies</i>

Background: In spite of advanced technologies and drug discoveries, morbidity and mortality were undoubtedly increasing in the era of contraception and abortion. Aims: Altruistic correlation of increasing morbidity, mortality, with contraception, abortion was planned for. Methods: In 2012, a retrospective analysis of prevalence of mortality in 350 patients of 20 - 35 years, 35 - 50 years and >50 years from data collected between 2003 and 2012 by convenient, stratified random sampling, from community, hospital, and its association with contraception and abortion status was undertaken;simultaneously, serum estrogen levels obtained from 105 patients were analyzed. In 2014, randomly chosen 8 males, of the 3 age groups, from a different community, whose life partners had undergone sterilization, were assessed for their serum testosterone levels. Results: Contraception users exhibited 3 - 4 fold increased mortality [p 50 years [p < 0.0005]. Endogenous estrogen was reduced in 75% [p < 0.0005] of contraceptive users. Plasma testosterone was reduced in males observing contraception, to less than 50% of normal, e.g. 1.3 ng/ml;66.6% contraception users aged 20 - 35 years had reduced [p < 0.0005] testosterone;100% of male contraception users aged 36 - 70 years showed reduced testosterone [p < 0.0005]. Conclusion: The “withered tree akin host” concept is contraception, abortion, with smashed fragmentation of germ cells. Reduced endogenous estrogen, androgen [dried up, destroyed life factors] result in deranged cell metabolism, cell cycle, and defaulted genomic repertoire, leading to failure of all established pharmacological therapeutics, including advanced technologies which yield gratifying results in non contracepted people today and in every one, before the era of contraception;subsets of people, host with contraception, with destroyed life factors, behave helplessly, concerning therapeutic applications, compared with subsets of people, host without contraception, with intact genomic repertoire, God ordained Life factors, make a remarkable recovery. Contraception reversal replants the germ cells [germ cells destruction stops], hormones rejuvenate to 79.9% of age normal, and diseases abate with recovery.