Radiotherapy is the most widely applied oncologic treatment modality utilizing ionizing radiation. A high degree of accuracy, reliability and reproducibility is required for a successful treatment outcome. Measurement...Radiotherapy is the most widely applied oncologic treatment modality utilizing ionizing radiation. A high degree of accuracy, reliability and reproducibility is required for a successful treatment outcome. Measurement using ionization chamber is a prerequisite for absorbed dose determination for external beam radiotherapy. Calibration coefficient is expressed in terms of air kerma and absorbed dose to water traceable to Secondary Standards Dosimetry Laboratory. The objective of this work was to evaluate the level of accuracy of ionization chamber used for clinical radiotherapy beam determination. Measurement and accuracy determination were carried out according to IAEA TRS 398 protocol. Clinical farmers type ionization chamber measurement and National Reference standard from Secondary Standards Dosimetry Laboratory were both exposed to cobalt-60 beam and measurement results compared under the same environmental conditions. The accuracy level between National Reference Standard and clinical radiotherapy standard was found to be −1.92% and −2.02% for air kerma and absorbed dose to water respectively. To minimize the effect of error and maximize therapeutic dose during treatment in order to achieve required clinical outcome, calibration factor was determined for air kerma (Nk) as 49.7 mGy/nC and absorbed dose to water ND, as 52.9 mGy/nC. The study established that radiotherapy beam measurement chain is prone to errors. Hence there is a need to independently verify the accuracy of radiation dose to ensure precision of dose delivery. The errors must be accounted for during clinical planning by factoring in calibration factor to minimize the systematic errors during treatment, and thereby providing enough room to achieve ±5% dose delivery to tumor target as recommended by ICRU.展开更多
Mammography x-rays standard is required to improve the quality of mammary machine and reduce the dose for w omen and staff. The molybdenum target x-rays machine is used as the radiation source and free-air cylindrical...Mammography x-rays standard is required to improve the quality of mammary machine and reduce the dose for w omen and staff. The molybdenum target x-rays machine is used as the radiation source and free-air cylindrical chamber is designed for detecting photon. Four standard radiation qualities are established w ith international standard documents as references. The Correction factors including air attenuation,scattered radiation,fluorescence,w all transmission,electron loss are studied in the four radiation quality. The uncertainty in absolute measurement of air-kerma includes air volume measurement of ionization chambers,current measurement,measurement of temperature and pressure,measurement of correction factors,physical constants and orientation of the reference distance. The relative combined standard uncertainty is 0.24%.展开更多
The air-kerma is one of the most important physical quantities in ionizing radiation dosimetry. The measurement of airkerma rate in narrow-spectrum series is the basis to determine the radiation dose at protection lev...The air-kerma is one of the most important physical quantities in ionizing radiation dosimetry. The measurement of airkerma rate in narrow-spectrum series is the basis to determine the radiation dose at protection level. In this article, the absolute measurement method is used to derive the standard air-kerma rate of the ISO 4037 narrow-spectrum series that ranges from 60 kV to 150 kV by a primary standard ionization chamber,it is used in direct comparison for air kerma. The indirect method is used to obtain the air-kerma rate by a secondary standard transfer ionization chamber named A5 chamber with calibration factors of the corresponding reference qualities. The results are very similar comparing between absolute and indirect methods for air-kerma rate, all the differences are within ±3.3%.展开更多
文摘Radiotherapy is the most widely applied oncologic treatment modality utilizing ionizing radiation. A high degree of accuracy, reliability and reproducibility is required for a successful treatment outcome. Measurement using ionization chamber is a prerequisite for absorbed dose determination for external beam radiotherapy. Calibration coefficient is expressed in terms of air kerma and absorbed dose to water traceable to Secondary Standards Dosimetry Laboratory. The objective of this work was to evaluate the level of accuracy of ionization chamber used for clinical radiotherapy beam determination. Measurement and accuracy determination were carried out according to IAEA TRS 398 protocol. Clinical farmers type ionization chamber measurement and National Reference standard from Secondary Standards Dosimetry Laboratory were both exposed to cobalt-60 beam and measurement results compared under the same environmental conditions. The accuracy level between National Reference Standard and clinical radiotherapy standard was found to be −1.92% and −2.02% for air kerma and absorbed dose to water respectively. To minimize the effect of error and maximize therapeutic dose during treatment in order to achieve required clinical outcome, calibration factor was determined for air kerma (Nk) as 49.7 mGy/nC and absorbed dose to water ND, as 52.9 mGy/nC. The study established that radiotherapy beam measurement chain is prone to errors. Hence there is a need to independently verify the accuracy of radiation dose to ensure precision of dose delivery. The errors must be accounted for during clinical planning by factoring in calibration factor to minimize the systematic errors during treatment, and thereby providing enough room to achieve ±5% dose delivery to tumor target as recommended by ICRU.
文摘Mammography x-rays standard is required to improve the quality of mammary machine and reduce the dose for w omen and staff. The molybdenum target x-rays machine is used as the radiation source and free-air cylindrical chamber is designed for detecting photon. Four standard radiation qualities are established w ith international standard documents as references. The Correction factors including air attenuation,scattered radiation,fluorescence,w all transmission,electron loss are studied in the four radiation quality. The uncertainty in absolute measurement of air-kerma includes air volume measurement of ionization chambers,current measurement,measurement of temperature and pressure,measurement of correction factors,physical constants and orientation of the reference distance. The relative combined standard uncertainty is 0.24%.
文摘The air-kerma is one of the most important physical quantities in ionizing radiation dosimetry. The measurement of airkerma rate in narrow-spectrum series is the basis to determine the radiation dose at protection level. In this article, the absolute measurement method is used to derive the standard air-kerma rate of the ISO 4037 narrow-spectrum series that ranges from 60 kV to 150 kV by a primary standard ionization chamber,it is used in direct comparison for air kerma. The indirect method is used to obtain the air-kerma rate by a secondary standard transfer ionization chamber named A5 chamber with calibration factors of the corresponding reference qualities. The results are very similar comparing between absolute and indirect methods for air-kerma rate, all the differences are within ±3.3%.
