This study investigated the occurrence of 19 aryl phosphates and mixed alkyl-aryl phosphates in dust samples(n=144)collected under the Canadian House Dust Study(CHDS).The predominant target analytes,detected in 100%of...This study investigated the occurrence of 19 aryl phosphates and mixed alkyl-aryl phosphates in dust samples(n=144)collected under the Canadian House Dust Study(CHDS).The predominant target analytes,detected in 100%of the samples,were isodecyl diphenyl phosphate(IDDPP),cresyl diphenyl phosphate(CDPP),and isopropylated triaryl phosphates(ITPs),with median concentrations of 1225(248-17850)ng/g,91(14-57700)ng/g,and 805(203-152000)ng/g,respectively.ITPs included isopropylphenyl diphenyl phosphate(IPPDPP),bis(isopropylphenyl)phenyl phosphate(BIPPPP),and tris(isopropylphenyl)phosphate(TIPPP).Strong correlations were found among IPPDPP,BIPPPP,and TIPPP,suggesting that there might be various consumer and building products containing mixtures of these substances.Bisphenol A bis(diphenyl phosphate)(BPA-DP)and resorcinol bis(diphenyl phosphate)(RBDP)were detected in 69%and 78%of samples,with relatively low median concentrations of 30(max:818)ng/g and 14(max:307)ng/g,respectively.Since the usage of OPEs as flame retardants has increased over the past decade,the current levels of OPEs in Canadian house dust could be higher than those reported in this study,where the samples were collected in 2007-2010.Further monitoring of OPEs in various environmental and biological matrices is recommended.展开更多
In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxi...In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxic Alternaric acid structure. The results displayed the information on modification of primary molecules and further synthesis of new bioactive compounds.展开更多
文摘This study investigated the occurrence of 19 aryl phosphates and mixed alkyl-aryl phosphates in dust samples(n=144)collected under the Canadian House Dust Study(CHDS).The predominant target analytes,detected in 100%of the samples,were isodecyl diphenyl phosphate(IDDPP),cresyl diphenyl phosphate(CDPP),and isopropylated triaryl phosphates(ITPs),with median concentrations of 1225(248-17850)ng/g,91(14-57700)ng/g,and 805(203-152000)ng/g,respectively.ITPs included isopropylphenyl diphenyl phosphate(IPPDPP),bis(isopropylphenyl)phenyl phosphate(BIPPPP),and tris(isopropylphenyl)phosphate(TIPPP).Strong correlations were found among IPPDPP,BIPPPP,and TIPPP,suggesting that there might be various consumer and building products containing mixtures of these substances.Bisphenol A bis(diphenyl phosphate)(BPA-DP)and resorcinol bis(diphenyl phosphate)(RBDP)were detected in 69%and 78%of samples,with relatively low median concentrations of 30(max:818)ng/g and 14(max:307)ng/g,respectively.Since the usage of OPEs as flame retardants has increased over the past decade,the current levels of OPEs in Canadian house dust could be higher than those reported in this study,where the samples were collected in 2007-2010.Further monitoring of OPEs in various environmental and biological matrices is recommended.
文摘In this paper, CoMFA method was applied to study the 3D QSAR on a series of 3 anilinomethylene 6 alkyl (aryl) 5,6 2H dihydropyran 2, 4 dione compounds, which were designed and synthesized referring to the natural toxic Alternaric acid structure. The results displayed the information on modification of primary molecules and further synthesis of new bioactive compounds.