The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effecti...The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields,展开更多
基金the National Natural Science Foundation of China(No. 21302095)Research Fund for the Doctoral Program of Higher Education of China(No. 20133221120003)+2 种基金Jiangsu Provincial NSFC(Nos. BK20130945, BK20130924)Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP)Nanjing Tech University for financial support
文摘The nucleophilic ring opening reaction of propargyl epoxides by amines based on a silver catalyst is presented, The reaction takes place under mild conditions and features a high regioselectivity to provide an effective method for the synthesis of 2-amino homopropargyl alcohols in moderate to high yields,