The Hong Kong and Shanghai stock markets look for synergies Shanghai and Hong Kong, the two cities striving to be China’s financial center, are setting aside their competitive differ ences to
Systematic physical simulation of thermo-mechanical processing routes has been ap-plied on a Gleeble 1500 simulator to four copper alloys (mass %) Cu-0.57Co-0.32Si,Cu-0.55Cr-0.065P, Cu-0.22Zr-0.035Si and Cu-1.01Ni-0.4...Systematic physical simulation of thermo-mechanical processing routes has been ap-plied on a Gleeble 1500 simulator to four copper alloys (mass %) Cu-0.57Co-0.32Si,Cu-0.55Cr-0.065P, Cu-0.22Zr-0.035Si and Cu-1.01Ni-0.43Si aimed at clarifying theinfluences of processing conditions on their final properties, strength and electricalconductivity. Flow curves were determined over wide temperature and strain rateranges. Hardness was used as a measure of the strength level achieved. High hard-ness was obtained as using equal amounts (strains 0.5) of cold deformation beforeand after the precipitation annealing stage. The maximum values achieved for theCu-Co-Si, Cu-Cr-P, Cu-Zr-Si and Cu-Ni-Si alloys were 190, 165, 178 and 193 HV5,respectively. A thermo-mechanical schedule involving the hot deformation-ageing-colddeformation stages showed even better results for the Cu-Zr-Si alloy. Consequently,the processing routes were designed based on simulation test results and wires of 5 and2mm in diameters have been successfully processed in the industrial scale.展开更多
Purpose:To study the association of blood pressure(BP)status on the optic disk structure as measured with the Heidelberg Retina Tomograph(HRT)in people without glaucoma.Design:Cross-sectional population-based setting ...Purpose:To study the association of blood pressure(BP)status on the optic disk structure as measured with the Heidelberg Retina Tomograph(HRT)in people without glaucoma.Design:Cross-sectional population-based setting study.Methods:Consecutive participants in the Thessaloniki Eye Study were included in this study.HRT images of the optic disk and BP measurements were taken.Hypertension was defined as a systolic BP(SBP)≥ 140 mmHg,diastolic BP(DBP)≥ 90 mmHg,or both.Subjects were classified in three groups by SBP and DBP.The Kruskal-Wallis test was used to compare the three groups with respect to the HRT parameters.Regression models adjusted for age,gender,height,disk size,intraocular pressure,cardiovascular disease,diabetes,and duration of antihypertensive treatment were used for each HRT parameter to compare values among the different groups.The P value was considered significant at<.05.Results:A total of 232 subjects were included in the analysis.Rim area was signifi cantly different among groups when DBP was considered as the criterion to classify subjects(P=.005).In regression models,cup area,and cup-to-disk(c/d)ratio were increased in subjects with normal DBP that was the result of treatment,as compared with both the high DBP and untreated normal DBP groups.Conclusions:In patients without glaucoma,the DBP< 90 mm Hg that results from antihypertensive treatment is associated with increased cupping and decreased rim area of the optic disk.This information should be considered in research aiming to define the role of the BP status as an independent factor initiating optic disk changes and/or as a contributing factor to glaucoma damage.展开更多
Formerly a self-governed profession, in the Province of Ontario, Canada, kinesiology was designated a regulated profession under the Regulated Health Professions Act (1991). The purpose of this study was to evaluate t...Formerly a self-governed profession, in the Province of Ontario, Canada, kinesiology was designated a regulated profession under the Regulated Health Professions Act (1991). The purpose of this study was to evaluate the perceptions of current health delivery agents to the regulation of kinesiology. An 18-item survey was used to collect data, and a SWOT (strengths, weaknesses, opportunities and threats) framework was used for analysis. The data indicated that kinesiology provides a unique expertise adding to client and patient care and is a needed partner within the multidisciplinary health environment. Similarly, despite the need for the profession to clearly define, delineate, and promote its scope of practice to professionals and to the public, there are increased opportunities that exist within the health care sector, particularly in chronic disease prevention. The addition of kinesiology as a regulated health profession was not considered to be a threat by existing key stakeholders.展开更多
Extremely long Australian paediatric outpatient waiting lists have resulted in large numbers of children waiting to see a paediatrician. Analyses of the patient referrals suggest that a large proportion of children ma...Extremely long Australian paediatric outpatient waiting lists have resulted in large numbers of children waiting to see a paediatrician. Analyses of the patient referrals suggest that a large proportion of children may benefit from allied health input, in addition to being seen by the paediatrician. This paper provides an organisational strategy that involves streamlining Allied Health clinical services in an effort to assist with bringing down a Paediatric Out-patient waitlist. The paper describes principles to guide the formation of a Paediatric Allied Health Multi-Disciplinary team that proposes assessment and brief interventions. The service would focus on supporting the paediatricians through the use of structured procedures, telephone intakes, multidisciplinary triage, shared and standardised assessments, collaborative formulations and reports, brief interventions, clinical-community linkages, and allied health student support. A variety of additional important organisational principles are proposed to facilitate patient flow from the perspective of streamlining administrative processes, having adequate administrative support, shared responsibilities, teamwork, flexibility, carrying out intake assessments, determining which referrals were appropriate for allied health, and working closely with medical staff.展开更多
'Acompany shall have its commitment to build a century-old business if it hopes to continue operation for a long time.'John Soo is the third generation of Chinese immigrants in Malaysia and CEO of Ally Biz Int...'Acompany shall have its commitment to build a century-old business if it hopes to continue operation for a long time.'John Soo is the third generation of Chinese immigrants in Malaysia and CEO of Ally Biz International Group. His forefathers were engaged in traditional plantation business. As a new-generation Malaysian Chinese who have received higher education and worked in many international companies as accountant or CEO, John Soo found that the business opportunities in traditional plantation industry has becoming slim. The challenge is to seek a better business project for new breakthroughs.展开更多
BACKGROUND In the past years,only a few studies with a limited number of adult patients analyzed clinical features of allied disorders of Hirschsprung’s disease(ADHD),most of which were individual case reports or lac...BACKGROUND In the past years,only a few studies with a limited number of adult patients analyzed clinical features of allied disorders of Hirschsprung’s disease(ADHD),most of which were individual case reports or lacked detailed clinical information.Although many studies have reported patients presenting to the emergency department(ED)with recurrent abdominal symptoms for a number of disorders,there are few data involving ADHD.However,owing to a lack of awareness of the disease,misdiagnoses and mistreatments are common.Severe complications such as perforation,bleeding,malabsorption,and even death in ADHD had been reported by many studies.AIM To assist ED clinicians in having a more comprehensive understanding of this disease and making an early suspected diagnosis of ADHD more effectively.METHODS We enrolled 53 patients who visited the ED and were eventually diagnosed with ADHD over the past 11 years in our hospital.Their basic information,clinical manifestations,and imaging findings were analyzed.Blood indices were compared between the ADHD and irritable bowel syndrome(IBS)groups.RESULTS Adult patients with ADHD had a mean age of 48.8±14.3 years,and 77.4%had been treated before admission.The transverse colon was the most common dilated part(73.6%),and constipation(67.9%)was the most common symptom.ADHD patients can present with uncommon symptoms and false-negative imaging findings.Logistic regression analysis indicated that body mass index(BMI)[odds ratio(OR)=0.786,P=0.013],cholinesterase(per 1000 units;OR=0.693,P=0.008),and blood chlorine(OR=0.816,P=0.022)were determined to be independent related factors between the ADHD and IBS groups.The area under the receiver operating characteristics curve of these three indices combined was 0.812(P<0.001).CONCLUSION Emergency physicians should be vigilant regarding patients with chronic constipation,abdominal pain,or abdominal distension,and consider the possibility of ADHD despite its rarity.Abdominal computed tomography examination is recommended as a useful tool in the suspected diagnosis of ADHD.BMI,cholinesterase,and blood chlorine have good discriminative abilities between ADHD and IBS.The nutritional status of adult patients with ADHD is worthy of further attention.Surgical treatment for adult patients with ADHD is important and inevitable.展开更多
The Beijing American Allied Signal Inc. Auto Division announced in Beijing in June that it will invest about US$100 million in expanding cooperation with China’s auto industry. Allied Signal Inc. is a leading manufac...The Beijing American Allied Signal Inc. Auto Division announced in Beijing in June that it will invest about US$100 million in expanding cooperation with China’s auto industry. Allied Signal Inc. is a leading manufacturer providing worldwide service in aero-space, auto, chemicals,展开更多
The Biden Administration has inherited its predecessor’s strategic perception about the growing competition among great powers.As a result,its policy toward China has been largely an extension of its predecessor’s,r...The Biden Administration has inherited its predecessor’s strategic perception about the growing competition among great powers.As a result,its policy toward China has been largely an extension of its predecessor’s,retaining the elements of competition and revising the instruments to outcompete China.The Biden Administration’s China policy has revolved around three pillars-allies,values,and high-tech,which it believes are America’s strengths in its relations with China.Since Biden took office,the United States has spent most of its diplomatic resources consolidating and building smaller security,economic,and tech alliances with membership restricted to democratic allies only,in an attempt to delink from China and consolidate its hegemonic status in the world.This policy carries the pernicious effect of plunging the world into Cold War-like confrontations.展开更多
Two terranes formed since the Late Palaeozoic can be distinguished in southwestern China. One is charac-terized by the Permo-Carboniferous ice-rafted marine gravel-bearing clastic formation and the cold-water faunaof ...Two terranes formed since the Late Palaeozoic can be distinguished in southwestern China. One is charac-terized by the Permo-Carboniferous ice-rafted marine gravel-bearing clastic formation and the cold-water faunaof the Gondwana facies, including the Gangmar Co, Lhasa, Sa' gya, Tengchong and Baoshan terranes and theother is marked by the Upper Palaeozoic of the Yangtze type with the Cathaysian flora and the Pacific-typefusulinids, comprising the Changning-Menglian, Shuangjiang-Lancang, Qamdo and Bayan Har terranes. TheLongmu Co-Shuanghu-Dengqen-North Lancang River-Kejie-Mengding suture zone between the two groups ofterranes is the boundary between Gondwana and Pacifica in southwestern China. On the grounds of thesedimentary formation and successive southwestward migration of the Asian nonmarine Jurassic-Cretaceousendemic bivalves, the ages of the suture and some terranes to the southwest of the suture zone are discussed.The Baoshan terrane and the Nyainrong-Sog terrane in the Lhasa composite terrane were firstly pieced togeth-er with the Asian continent in the early Early Jurassic. The northern Tibet-western Yunnan microplate, in-cluding the Gangmar Co, Lhasa and Tengchong terranes, collided with the Asian continent at the end of theEarly Cretaceous Neocomian.展开更多
The Shanghai Household CosmeticsAllied Corporation was establishedin 1898. It is the earliest national cosmeticsenterprise in China. From the GuangSheng Hang(an old firm)in Qing dynastyto a group corporation with mode...The Shanghai Household CosmeticsAllied Corporation was establishedin 1898. It is the earliest national cosmeticsenterprise in China. From the GuangSheng Hang(an old firm)in Qing dynastyto a group corporation with modern scaleoperation today, almost a century haselapsed from beginning to end. Thedevelopment of the Shanghai HouseholdCosmetics Corporation bears witness tothe national cosmetics industry’s growthfrom small to large, and from weak tostrong. After entering the 1980s, theShanghai Household CosmeticsCorporation has made considerableprogress, especially in recent years, underthe guidance of the operating strategy展开更多
Objective: To evaluate cytokine levels (IL-1β,TNF-α,IL-6, IL-8), soluble intercellular adhesion molecule-1 (sICAM-1)-and number of macrophages in peritoneal fluid (PF)of women with no minimal endometriosis and assoc...Objective: To evaluate cytokine levels (IL-1β,TNF-α,IL-6, IL-8), soluble intercellular adhesion molecule-1 (sICAM-1)-and number of macrophages in peritoneal fluid (PF)of women with no minimal endometriosis and associated (or not) infertility in order to discriminate between infertility and/or endometriosis. Study design: Cytokines and sICAM-1 were measured by using quantitative enzyme-linked immunosorbent assay (ELISA) while the macrophages were identified by May-Grunwald-Giemsa and non-specific esterase staining and presented as medians. The measurements were performed in 78 women belonging to four selected subgroups according to their endometriosis and/or infertility status. Statistical analysis was performed using Kruskal-Wallis non-parametric ANOVA test. Additionally, discriminant function analyses were performed. Results: We have found the most elevated macrophage numbers in the groups of women with endometriosis. IL-1βdid not present any statistically significant values differentiating the analysed subgroups. IL-6 (110.0 pg/ml) and TNF-αexhibited the highest concentrations (statistically significant) in a group of fertile women with endometriosis. IL-8 clearly differentiated between the subgroups with infertility and sICAM-1 was statistically significantly elevated in the subgroups of infertile women. In the forward discriminant analysis, when subdividing the studied population according to its infertility status (we considered macrophages, IL-8 and IL-6 in order of probability values), we have found striking probability value of 92%for the correct classification into an infertile population. Conclusion: Out of the range of the analysed factors we have found only the sICAM-1 to be singled out between the standard discriminant analysis and the forward one. However, this important flagging molecule might be of considerable value for discrimination between different types of pathology at the level of immune effector function. The increased levels of TNF-αand IL-6 signified a group of fertile women with endometriosis; however only IL-6 presented a discriminating value in multifunctional analysis of examined subgroups. The analysed range of factors had a greater tendency to discriminate between infertility status rather than endometriosis.展开更多
Purpose: To compare the reduction of conjunctival bacterial flora by povidone -iodine 4%,ofloxacin 0.3%, and chlorhexidine 0.05%for endophthalmitis prophy laxis before corneal suture removal in an outpatient setting. ...Purpose: To compare the reduction of conjunctival bacterial flora by povidone -iodine 4%,ofloxacin 0.3%, and chlorhexidine 0.05%for endophthalmitis prophy laxis before corneal suture removal in an outpatient setting. Methods: In each g roup of 25 consecutive subjects who presented for outpatient ophthalmic evaluati on, one eye was treated with either povidone-iodine4%(PI), ofloxacin 0.3%(Ofl ox) or chlorhexidine 0.05%(Chex). The other eye served as a control. Three minu tes after treatment, cultures were taken from the inferior conjunctival sac in b oth eyes. Following incubation at 35°for 48 hours, the numbers of colonies were counted and compared. The difference in the numbers of colonies in each pair of treated and control eyeswas assessed for each drug and compared. Results: The r eduction in colony-formingunits was highly significant for each of the three dr ugs tested (Wilcoxon signed-ranks test; p < 0.0001). There was no significant d ifference between percent reduction by the three drugs (Kruskal-Wallis test; p= 0.68). Sterile cultures following preparation by PI, Oflox and Chex were obtaine d in 52%, 68%and 52%, respectively. Conclusions: The regimens tested were sim ilarly effective in reducing conjunctival commensals. They may all be considered as options for a quick prophylaxis against infection following suture removal i n an outpatient setting.展开更多
Objective: To investigate the effects of hormone therapy, estrogen therapy and tibolone on markers of apoptosis including bcl-2, and bax and cyclin D 1 expression in postmenopausal vaginal epithelium. Study design: Th...Objective: To investigate the effects of hormone therapy, estrogen therapy and tibolone on markers of apoptosis including bcl-2, and bax and cyclin D 1 expression in postmenopausal vaginal epithelium. Study design: Thirty postmenopausal women were randomized to the treatment protocols (0.625 mg conjugated equine estrogen (CEE) ? 2.5 mg medroxyprogesterone acetate (MPA); 2 mg estradiol valerate; 2.5 mg tibolone). After baseline vaginal biopsy, control biopsies were performed after 70 days following the initiation of the therapy. Bcl-2, bax, Bcl-2/bax ratio, cyclin D1 measurements were performed immunohistochemically. Data were analyzed by Kruskal-Wallis, Mann-Whitney U and Wilcoxon tests. Results: After the treatment period the above-mentioned parameters were not different among the groups except for cyclin D1 levels. Cyclin D1 expression was found to be strong in patients with treated estradiol valerate. Conclusions: The effects of estrogen on cyclin D1 expression were not detected with tibolone or with the addition of progesterone to estrogen in the vaginal epithelium. Cyclin D1 appeared to have stronger effects on the estrogen related proliferation compared to apoptotic markers in vaginal epithelial cells.展开更多
文摘The Hong Kong and Shanghai stock markets look for synergies Shanghai and Hong Kong, the two cities striving to be China’s financial center, are setting aside their competitive differ ences to
基金the National Natural Science Foundation of China(Nos.51822509,51701034)the Scientific and Technological Research Program of Chongqing Municipal Education Commission,China(Nos.KJQN201801137,KJQN201901106)the Basic and Advanced Research Project of CQ CSTC,China(No.cstc2018jcyjAX0035).
文摘Systematic physical simulation of thermo-mechanical processing routes has been ap-plied on a Gleeble 1500 simulator to four copper alloys (mass %) Cu-0.57Co-0.32Si,Cu-0.55Cr-0.065P, Cu-0.22Zr-0.035Si and Cu-1.01Ni-0.43Si aimed at clarifying theinfluences of processing conditions on their final properties, strength and electricalconductivity. Flow curves were determined over wide temperature and strain rateranges. Hardness was used as a measure of the strength level achieved. High hard-ness was obtained as using equal amounts (strains 0.5) of cold deformation beforeand after the precipitation annealing stage. The maximum values achieved for theCu-Co-Si, Cu-Cr-P, Cu-Zr-Si and Cu-Ni-Si alloys were 190, 165, 178 and 193 HV5,respectively. A thermo-mechanical schedule involving the hot deformation-ageing-colddeformation stages showed even better results for the Cu-Zr-Si alloy. Consequently,the processing routes were designed based on simulation test results and wires of 5 and2mm in diameters have been successfully processed in the industrial scale.
文摘Purpose:To study the association of blood pressure(BP)status on the optic disk structure as measured with the Heidelberg Retina Tomograph(HRT)in people without glaucoma.Design:Cross-sectional population-based setting study.Methods:Consecutive participants in the Thessaloniki Eye Study were included in this study.HRT images of the optic disk and BP measurements were taken.Hypertension was defined as a systolic BP(SBP)≥ 140 mmHg,diastolic BP(DBP)≥ 90 mmHg,or both.Subjects were classified in three groups by SBP and DBP.The Kruskal-Wallis test was used to compare the three groups with respect to the HRT parameters.Regression models adjusted for age,gender,height,disk size,intraocular pressure,cardiovascular disease,diabetes,and duration of antihypertensive treatment were used for each HRT parameter to compare values among the different groups.The P value was considered significant at<.05.Results:A total of 232 subjects were included in the analysis.Rim area was signifi cantly different among groups when DBP was considered as the criterion to classify subjects(P=.005).In regression models,cup area,and cup-to-disk(c/d)ratio were increased in subjects with normal DBP that was the result of treatment,as compared with both the high DBP and untreated normal DBP groups.Conclusions:In patients without glaucoma,the DBP< 90 mm Hg that results from antihypertensive treatment is associated with increased cupping and decreased rim area of the optic disk.This information should be considered in research aiming to define the role of the BP status as an independent factor initiating optic disk changes and/or as a contributing factor to glaucoma damage.
文摘Formerly a self-governed profession, in the Province of Ontario, Canada, kinesiology was designated a regulated profession under the Regulated Health Professions Act (1991). The purpose of this study was to evaluate the perceptions of current health delivery agents to the regulation of kinesiology. An 18-item survey was used to collect data, and a SWOT (strengths, weaknesses, opportunities and threats) framework was used for analysis. The data indicated that kinesiology provides a unique expertise adding to client and patient care and is a needed partner within the multidisciplinary health environment. Similarly, despite the need for the profession to clearly define, delineate, and promote its scope of practice to professionals and to the public, there are increased opportunities that exist within the health care sector, particularly in chronic disease prevention. The addition of kinesiology as a regulated health profession was not considered to be a threat by existing key stakeholders.
文摘Extremely long Australian paediatric outpatient waiting lists have resulted in large numbers of children waiting to see a paediatrician. Analyses of the patient referrals suggest that a large proportion of children may benefit from allied health input, in addition to being seen by the paediatrician. This paper provides an organisational strategy that involves streamlining Allied Health clinical services in an effort to assist with bringing down a Paediatric Out-patient waitlist. The paper describes principles to guide the formation of a Paediatric Allied Health Multi-Disciplinary team that proposes assessment and brief interventions. The service would focus on supporting the paediatricians through the use of structured procedures, telephone intakes, multidisciplinary triage, shared and standardised assessments, collaborative formulations and reports, brief interventions, clinical-community linkages, and allied health student support. A variety of additional important organisational principles are proposed to facilitate patient flow from the perspective of streamlining administrative processes, having adequate administrative support, shared responsibilities, teamwork, flexibility, carrying out intake assessments, determining which referrals were appropriate for allied health, and working closely with medical staff.
文摘'Acompany shall have its commitment to build a century-old business if it hopes to continue operation for a long time.'John Soo is the third generation of Chinese immigrants in Malaysia and CEO of Ally Biz International Group. His forefathers were engaged in traditional plantation business. As a new-generation Malaysian Chinese who have received higher education and worked in many international companies as accountant or CEO, John Soo found that the business opportunities in traditional plantation industry has becoming slim. The challenge is to seek a better business project for new breakthroughs.
基金the Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine,No. 2017-XK-A36
文摘BACKGROUND In the past years,only a few studies with a limited number of adult patients analyzed clinical features of allied disorders of Hirschsprung’s disease(ADHD),most of which were individual case reports or lacked detailed clinical information.Although many studies have reported patients presenting to the emergency department(ED)with recurrent abdominal symptoms for a number of disorders,there are few data involving ADHD.However,owing to a lack of awareness of the disease,misdiagnoses and mistreatments are common.Severe complications such as perforation,bleeding,malabsorption,and even death in ADHD had been reported by many studies.AIM To assist ED clinicians in having a more comprehensive understanding of this disease and making an early suspected diagnosis of ADHD more effectively.METHODS We enrolled 53 patients who visited the ED and were eventually diagnosed with ADHD over the past 11 years in our hospital.Their basic information,clinical manifestations,and imaging findings were analyzed.Blood indices were compared between the ADHD and irritable bowel syndrome(IBS)groups.RESULTS Adult patients with ADHD had a mean age of 48.8±14.3 years,and 77.4%had been treated before admission.The transverse colon was the most common dilated part(73.6%),and constipation(67.9%)was the most common symptom.ADHD patients can present with uncommon symptoms and false-negative imaging findings.Logistic regression analysis indicated that body mass index(BMI)[odds ratio(OR)=0.786,P=0.013],cholinesterase(per 1000 units;OR=0.693,P=0.008),and blood chlorine(OR=0.816,P=0.022)were determined to be independent related factors between the ADHD and IBS groups.The area under the receiver operating characteristics curve of these three indices combined was 0.812(P<0.001).CONCLUSION Emergency physicians should be vigilant regarding patients with chronic constipation,abdominal pain,or abdominal distension,and consider the possibility of ADHD despite its rarity.Abdominal computed tomography examination is recommended as a useful tool in the suspected diagnosis of ADHD.BMI,cholinesterase,and blood chlorine have good discriminative abilities between ADHD and IBS.The nutritional status of adult patients with ADHD is worthy of further attention.Surgical treatment for adult patients with ADHD is important and inevitable.
文摘The Beijing American Allied Signal Inc. Auto Division announced in Beijing in June that it will invest about US$100 million in expanding cooperation with China’s auto industry. Allied Signal Inc. is a leading manufacturer providing worldwide service in aero-space, auto, chemicals,
文摘The Biden Administration has inherited its predecessor’s strategic perception about the growing competition among great powers.As a result,its policy toward China has been largely an extension of its predecessor’s,retaining the elements of competition and revising the instruments to outcompete China.The Biden Administration’s China policy has revolved around three pillars-allies,values,and high-tech,which it believes are America’s strengths in its relations with China.Since Biden took office,the United States has spent most of its diplomatic resources consolidating and building smaller security,economic,and tech alliances with membership restricted to democratic allies only,in an attempt to delink from China and consolidate its hegemonic status in the world.This policy carries the pernicious effect of plunging the world into Cold War-like confrontations.
文摘Two terranes formed since the Late Palaeozoic can be distinguished in southwestern China. One is charac-terized by the Permo-Carboniferous ice-rafted marine gravel-bearing clastic formation and the cold-water faunaof the Gondwana facies, including the Gangmar Co, Lhasa, Sa' gya, Tengchong and Baoshan terranes and theother is marked by the Upper Palaeozoic of the Yangtze type with the Cathaysian flora and the Pacific-typefusulinids, comprising the Changning-Menglian, Shuangjiang-Lancang, Qamdo and Bayan Har terranes. TheLongmu Co-Shuanghu-Dengqen-North Lancang River-Kejie-Mengding suture zone between the two groups ofterranes is the boundary between Gondwana and Pacifica in southwestern China. On the grounds of thesedimentary formation and successive southwestward migration of the Asian nonmarine Jurassic-Cretaceousendemic bivalves, the ages of the suture and some terranes to the southwest of the suture zone are discussed.The Baoshan terrane and the Nyainrong-Sog terrane in the Lhasa composite terrane were firstly pieced togeth-er with the Asian continent in the early Early Jurassic. The northern Tibet-western Yunnan microplate, in-cluding the Gangmar Co, Lhasa and Tengchong terranes, collided with the Asian continent at the end of theEarly Cretaceous Neocomian.
文摘The Shanghai Household CosmeticsAllied Corporation was establishedin 1898. It is the earliest national cosmeticsenterprise in China. From the GuangSheng Hang(an old firm)in Qing dynastyto a group corporation with modern scaleoperation today, almost a century haselapsed from beginning to end. Thedevelopment of the Shanghai HouseholdCosmetics Corporation bears witness tothe national cosmetics industry’s growthfrom small to large, and from weak tostrong. After entering the 1980s, theShanghai Household CosmeticsCorporation has made considerableprogress, especially in recent years, underthe guidance of the operating strategy
文摘Objective: To evaluate cytokine levels (IL-1β,TNF-α,IL-6, IL-8), soluble intercellular adhesion molecule-1 (sICAM-1)-and number of macrophages in peritoneal fluid (PF)of women with no minimal endometriosis and associated (or not) infertility in order to discriminate between infertility and/or endometriosis. Study design: Cytokines and sICAM-1 were measured by using quantitative enzyme-linked immunosorbent assay (ELISA) while the macrophages were identified by May-Grunwald-Giemsa and non-specific esterase staining and presented as medians. The measurements were performed in 78 women belonging to four selected subgroups according to their endometriosis and/or infertility status. Statistical analysis was performed using Kruskal-Wallis non-parametric ANOVA test. Additionally, discriminant function analyses were performed. Results: We have found the most elevated macrophage numbers in the groups of women with endometriosis. IL-1βdid not present any statistically significant values differentiating the analysed subgroups. IL-6 (110.0 pg/ml) and TNF-αexhibited the highest concentrations (statistically significant) in a group of fertile women with endometriosis. IL-8 clearly differentiated between the subgroups with infertility and sICAM-1 was statistically significantly elevated in the subgroups of infertile women. In the forward discriminant analysis, when subdividing the studied population according to its infertility status (we considered macrophages, IL-8 and IL-6 in order of probability values), we have found striking probability value of 92%for the correct classification into an infertile population. Conclusion: Out of the range of the analysed factors we have found only the sICAM-1 to be singled out between the standard discriminant analysis and the forward one. However, this important flagging molecule might be of considerable value for discrimination between different types of pathology at the level of immune effector function. The increased levels of TNF-αand IL-6 signified a group of fertile women with endometriosis; however only IL-6 presented a discriminating value in multifunctional analysis of examined subgroups. The analysed range of factors had a greater tendency to discriminate between infertility status rather than endometriosis.
文摘Purpose: To compare the reduction of conjunctival bacterial flora by povidone -iodine 4%,ofloxacin 0.3%, and chlorhexidine 0.05%for endophthalmitis prophy laxis before corneal suture removal in an outpatient setting. Methods: In each g roup of 25 consecutive subjects who presented for outpatient ophthalmic evaluati on, one eye was treated with either povidone-iodine4%(PI), ofloxacin 0.3%(Ofl ox) or chlorhexidine 0.05%(Chex). The other eye served as a control. Three minu tes after treatment, cultures were taken from the inferior conjunctival sac in b oth eyes. Following incubation at 35°for 48 hours, the numbers of colonies were counted and compared. The difference in the numbers of colonies in each pair of treated and control eyeswas assessed for each drug and compared. Results: The r eduction in colony-formingunits was highly significant for each of the three dr ugs tested (Wilcoxon signed-ranks test; p < 0.0001). There was no significant d ifference between percent reduction by the three drugs (Kruskal-Wallis test; p= 0.68). Sterile cultures following preparation by PI, Oflox and Chex were obtaine d in 52%, 68%and 52%, respectively. Conclusions: The regimens tested were sim ilarly effective in reducing conjunctival commensals. They may all be considered as options for a quick prophylaxis against infection following suture removal i n an outpatient setting.
文摘Objective: To investigate the effects of hormone therapy, estrogen therapy and tibolone on markers of apoptosis including bcl-2, and bax and cyclin D 1 expression in postmenopausal vaginal epithelium. Study design: Thirty postmenopausal women were randomized to the treatment protocols (0.625 mg conjugated equine estrogen (CEE) ? 2.5 mg medroxyprogesterone acetate (MPA); 2 mg estradiol valerate; 2.5 mg tibolone). After baseline vaginal biopsy, control biopsies were performed after 70 days following the initiation of the therapy. Bcl-2, bax, Bcl-2/bax ratio, cyclin D1 measurements were performed immunohistochemically. Data were analyzed by Kruskal-Wallis, Mann-Whitney U and Wilcoxon tests. Results: After the treatment period the above-mentioned parameters were not different among the groups except for cyclin D1 levels. Cyclin D1 expression was found to be strong in patients with treated estradiol valerate. Conclusions: The effects of estrogen on cyclin D1 expression were not detected with tibolone or with the addition of progesterone to estrogen in the vaginal epithelium. Cyclin D1 appeared to have stronger effects on the estrogen related proliferation compared to apoptotic markers in vaginal epithelial cells.