Cardiac resynchronization therapy(CRT) is a new therapeutic option for patients who have drug-refractory end-stage heart failure. Much information has been obtained from patients who have sinus rhythm, but the use of ...Cardiac resynchronization therapy(CRT) is a new therapeutic option for patients who have drug-refractory end-stage heart failure. Much information has been obtained from patients who have sinus rhythm, but the use of CRT in patients who have chronic atrial fibrillation(AF) has not been studied extensively. Accordingly, we evaluated the clinical response and long-term survival rate of CRT in patients who had heart failure and chronic AF, and the results were compared with those in patients who had sinus rhythm and who underwent CRT. Sixty patients who had end-stage heart failure(30 had sinus rhythm and 30 had chronic AF), New York Heart Association classes III to IV, left ventricular ejection fraction< 35%, QRS interval >120 ms, and a left bundle branch block received a biventricular pacemaker. New York Heart Association class, Minnesota Quality of Life score, and 6-minutew-alking distance were evaluated at baseline and after 6 months of CRT. Longterm follow-up was ≤2 years. New York Heart Association class, Minnesota Quality of Life score, and 6-minute walking distance improved significantly in the 2 groups after 6 months of CRT. The number of nonresponders was greater among patients who had AF.Nevertheless, the long-term survival rate was comparable between patients who had sinus rhythm and those who had AF. Patients who had AF demonstrated comparable benefit from CRT as those who had sinus rhythm.展开更多
间歇性禁食是一种新的饮食干预方法,已被证明可提高肿瘤治疗的疗效并减少并发症。时间限制性饮食是间歇性禁食的一种特殊形式。据一篇发表在Journal of Nutritional Oncology 2023年1期的文章Potential Preventive Effects of Time-Rest...间歇性禁食是一种新的饮食干预方法,已被证明可提高肿瘤治疗的疗效并减少并发症。时间限制性饮食是间歇性禁食的一种特殊形式。据一篇发表在Journal of Nutritional Oncology 2023年1期的文章Potential Preventive Effects of Time-Restricted Eating on Cancer报道,它通常只限制每天的进食时间,而不限制摄入的热量。除了像其他间歇性禁食方法一样,有利于体重管理和改善新陈代谢的特点外,限时饮食还能使昼夜节律同步化,并影响细胞自噬水平,具有潜在的抗衰老作用。展开更多
选择性5-羟色胺再摄取抑制剂selective serotonin reuptake inhibitor（SSRI）血管内血栓切除术endovascular thrombectomy（ET）小梗死灶和前循环近端闭塞性缺血性卒中血管内治疗并强调最短化CT扫描至再通时间试验Endovascular Treatme...选择性5-羟色胺再摄取抑制剂selective serotonin reuptake inhibitor（SSRI）血管内血栓切除术endovascular thrombectomy（ET）小梗死灶和前循环近端闭塞性缺血性卒中血管内治疗并强调最短化CT扫描至再通时间试验Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion with Emphasis on Minimizing CT to Recanalization Times （ESCAPE）trial阳性和阴性症状量表Positive and Negative Syndrome Scale（PANSS）.展开更多
文摘Cardiac resynchronization therapy(CRT) is a new therapeutic option for patients who have drug-refractory end-stage heart failure. Much information has been obtained from patients who have sinus rhythm, but the use of CRT in patients who have chronic atrial fibrillation(AF) has not been studied extensively. Accordingly, we evaluated the clinical response and long-term survival rate of CRT in patients who had heart failure and chronic AF, and the results were compared with those in patients who had sinus rhythm and who underwent CRT. Sixty patients who had end-stage heart failure(30 had sinus rhythm and 30 had chronic AF), New York Heart Association classes III to IV, left ventricular ejection fraction< 35%, QRS interval >120 ms, and a left bundle branch block received a biventricular pacemaker. New York Heart Association class, Minnesota Quality of Life score, and 6-minutew-alking distance were evaluated at baseline and after 6 months of CRT. Longterm follow-up was ≤2 years. New York Heart Association class, Minnesota Quality of Life score, and 6-minute walking distance improved significantly in the 2 groups after 6 months of CRT. The number of nonresponders was greater among patients who had AF.Nevertheless, the long-term survival rate was comparable between patients who had sinus rhythm and those who had AF. Patients who had AF demonstrated comparable benefit from CRT as those who had sinus rhythm.
文摘间歇性禁食是一种新的饮食干预方法,已被证明可提高肿瘤治疗的疗效并减少并发症。时间限制性饮食是间歇性禁食的一种特殊形式。据一篇发表在Journal of Nutritional Oncology 2023年1期的文章Potential Preventive Effects of Time-Restricted Eating on Cancer报道,它通常只限制每天的进食时间,而不限制摄入的热量。除了像其他间歇性禁食方法一样,有利于体重管理和改善新陈代谢的特点外,限时饮食还能使昼夜节律同步化,并影响细胞自噬水平,具有潜在的抗衰老作用。
文摘选择性5-羟色胺再摄取抑制剂selective serotonin reuptake inhibitor（SSRI）血管内血栓切除术endovascular thrombectomy（ET）小梗死灶和前循环近端闭塞性缺血性卒中血管内治疗并强调最短化CT扫描至再通时间试验Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion with Emphasis on Minimizing CT to Recanalization Times （ESCAPE）trial阳性和阴性症状量表Positive and Negative Syndrome Scale（PANSS）.
