Alternaria mycotoxins are of concern due to its adverse health effect, they affect various cereal crops and grain-based food along with modified forms that contribute to overall exposure. This study aimed to determine...Alternaria mycotoxins are of concern due to its adverse health effect, they affect various cereal crops and grain-based food along with modified forms that contribute to overall exposure. This study aimed to determine the frequency and level of exposure to Alternaria mycotoxins(tenuazonic acid, TeA;alternariol, AOH;alternariol monomethyl ether, AME;tentoxin, TEN;and altenuene, ALT) in human urine from Beijing adults. A total of 2212 urine samples were collected and analyzed for five mycotoxins using LC–ESI–MS/MS. More than98% of the samples had at least one Alternaria mycotoxin detected. Among the mycotoxins,AME had the highest detection rate(96.0%), followed by TeA(70.5%). The calculated average daily intake values of AME(12.5 ng/kg b.w.) was 5 times the TTC value(2.5 ng/kg b.w.) set by the EFSA, indicating the potential health risks associated with mycotoxins. Immediate attention and subsequent actions should be taken to identify the sources of mycotoxins and the corresponding exposure pathways to humans in the investigated regions.展开更多
Mycotoxins are secondary metabolites produced and accumulated by mould. This study assessed the ability of 89 lactic acid bacteria, isolated from different sources, to degrade two mycotoxins by Alternaria: alternariol...Mycotoxins are secondary metabolites produced and accumulated by mould. This study assessed the ability of 89 lactic acid bacteria, isolated from different sources, to degrade two mycotoxins by Alternaria: alternariol and altenuene. The mehodology employed was the thin layer chromatography. The results obtained allow us to demonstrate that a 16.85% of the strains (15/89 strains) are capable of decreasing the intensity of the band related at the alternariol and 14.60% (13/89 strains) is capable of decrease the intensity of the band that manifests the altenuane in Alufolium. All tests have been observed under wavelengths of 360 nm and 255 nm. The results obtained allow carrying out a selection of lactic acid strains capable of degrading or decreasing the concentration of mycotoxins selected for this.展开更多
基金supported by the National Key Research and Development Program of China (Nos. 2017YFC1600500, 2019YFF0216303)the Research Special Found for Municipal Medical Public Welfare institute (No. 2017-BJYJ-15)the Research Project of the National Institute of Metrology (Nos. AKY1934, 31-AKYZZ2039)。
文摘Alternaria mycotoxins are of concern due to its adverse health effect, they affect various cereal crops and grain-based food along with modified forms that contribute to overall exposure. This study aimed to determine the frequency and level of exposure to Alternaria mycotoxins(tenuazonic acid, TeA;alternariol, AOH;alternariol monomethyl ether, AME;tentoxin, TEN;and altenuene, ALT) in human urine from Beijing adults. A total of 2212 urine samples were collected and analyzed for five mycotoxins using LC–ESI–MS/MS. More than98% of the samples had at least one Alternaria mycotoxin detected. Among the mycotoxins,AME had the highest detection rate(96.0%), followed by TeA(70.5%). The calculated average daily intake values of AME(12.5 ng/kg b.w.) was 5 times the TTC value(2.5 ng/kg b.w.) set by the EFSA, indicating the potential health risks associated with mycotoxins. Immediate attention and subsequent actions should be taken to identify the sources of mycotoxins and the corresponding exposure pathways to humans in the investigated regions.
文摘Mycotoxins are secondary metabolites produced and accumulated by mould. This study assessed the ability of 89 lactic acid bacteria, isolated from different sources, to degrade two mycotoxins by Alternaria: alternariol and altenuene. The mehodology employed was the thin layer chromatography. The results obtained allow us to demonstrate that a 16.85% of the strains (15/89 strains) are capable of decreasing the intensity of the band related at the alternariol and 14.60% (13/89 strains) is capable of decrease the intensity of the band that manifests the altenuane in Alufolium. All tests have been observed under wavelengths of 360 nm and 255 nm. The results obtained allow carrying out a selection of lactic acid strains capable of degrading or decreasing the concentration of mycotoxins selected for this.
