Multichannel Blind CT Image Restoration via Variable Splitting and Alternating Direction Method

Computed tomography(CT) blurring caused by point spread function leads to errors in quantification and visualization. In this paper, multichannel blind CT image restoration is proposed to overcome the effect of point spread function. The main advantage from multichannel blind CT image restoration is to exploit the diversity and redundancy of information in different acquisitions. The proposed approach is based on a variable splitting to obtain an equivalent constrained optimization formulation, which is addressed with the alternating direction method of multipliers and simply implemented in the Fourier domain. Numerical experiments illustrate that our method obtains a higher average gain value of at least 1.21 d B in terms of Q metric than the other methods, and it requires only 7 iterations of alternating minimization to obtain a fast convergence.

Non-invasive electrical brain stimulation:from acute to late-stage treatment of central nervous system damage

Non-invasive brain current stimulation（NIBS） is a promising and versatile tool for inducing neuroplasticity,protection and functional rehabilitation of damaged neuronal systems.It is technically simple,requires no surgery,and has significant beneficial effects.However,there are various technical approaches for NIBS which influence neuronal networks in significantly different ways.Transcranial direct current stimulation（t DCS）,alternating current stimulation（ACS） and repetitive transcranial magnetic stimulation（r TMS） all have been applied to modulate brain activity in animal experiments under normal and pathological conditions.Also clinical trials have shown that t DCS,r TMS and ACS induce significant behavioural effects and can – depending on the parameters chosen – enhance or decrease brain excitability and influence performance and learning as well as rehabilitation and protective mechanisms.The diverse phaenomena and partially opposing effects of NIBS are not yet fully understood and mechanisms of action need to be explored further in order to select appropriate parameters for a given task,such as current type and strength,timing,distribution of current densities and electrode position.In this review,we will discuss the various parameters which need to be considered when designing a NIBS protocol and will put them into context with the envisaged applications in experimental neurobiology and medicine such as vision restoration,motor rehabilitation and cognitive enhancement.