Correlation between Pulmonary Endothelin Receptors and Alveolar-arterial Oxygen Gradient in Rats with Hepatopulmonary Syndrome

The correlation between pulmonary endothelin receptors and alveolar-arterial oxygen gradient （A aDO2） in rats with hepatopulmonary syndrome was investigated. Animals were divided into 2 groups： Sham operated （Sham） group and common bile duct ligation （CBDL） group. Arterial blood gas was evaluated by a blood gas analyzer. The concentrations of ET-1 in blood and lung tissue sample were evaluated by radioimmunoassay. The distribution and expression of two kinds of subtype receptor of ET-1, ETRA and ETRB were examined by in situ hybridization. The results showed that the level of A aDO2, was higher in CBDI. group than that in Sham group （P〈0.05）. The levels of plasma and pulmonary ET-1 in CBDL group were both higher than in Sham group （P〈0.05 ）. There was no significant difference in average A of ETRA between two groups by imaging analysis （0.21±0.06 vs 0.22±0.08, P〉0.05）, while that of ETRB was higher in CBDI. group than in Sham group （0.58±0.16 vs 0.28±0.07, P〈0.05）. The expression of ETRBinlung was positively correlated with A aDO2（P〈0.05）. It was concluded that the widened A-aDO2 may be related with enhancement of the expression of ETRB in lung.

Use of venous-to-arterial carbon dioxide tension difference to guide resuscitation therapy in septic shock

The mixed venous-to-arterial carbon dioxide(CO_2)tension difference[P(v-a) CO_2]is the difference between carbon dioxide tension(PCO_2) in mixed venous blood(sampled from a pulmonary artery catheter) and the PCO_2 in arterial blood.P(v-a) CO_2 depends on the cardiac output and the global CO_2 production,and on the complex relationship between PCO_2 and CO_2 content.Experimental and clinical studies support the evidence that P(v-a) CO_2 cannot serve as an indicator of tissue hypoxia,and should be regarded as an indicator of the adequacy of venous blood to wash out the total CO_2generated by the peripheral tissues.P(v-a) CO_2 can be replaced by the central venous-to-arterial CO_2 difference(△PCO_2),which is calculated from simultaneous sampling of central venous blood from a central vein catheter and arterial blood and,therefore,more easy to obtain at the bedside.Determining the △PCO_2 during the resuscitation of septic shock patients might be useful when deciding when to continue resuscitation despite a central venous oxygen saturation(SCVO_2) > 70%associated with elevated blood lactate levels.Because high blood lactate levels is not a discriminatory factor in determining the source of that stress,an increased △PCO_2(> 6 mmHg)could be used to identify patients who still remain inadequately resuscitated.Monitoring the △PCO_2 from the beginning of the reanimation of septic shock patients might be a valuable means to evaluate the adequacy of cardiac output in tissue perfusion and,thus,guiding the therapy.In this respect,it can aid to titrate inotropes to adjust oxygen delivery to CO_2 production,or to choose between hemoglobin correction or fluid/inotrope infusion in patients with a too low ScvO_2 related to metabolic demand.The combination of P(v-a) CO_2 or △PCO_2 with oxygen-derived parameters through the calculation of the P(v-a) CO_2 or △PCO_2/arteriovenous oxygen content difference ratio can detect the presence of global anaerobic metabolism.

Clinical Efficacy of Hyperbaric Oxygen Therapy at Different Pressures in the Treatment of Sudden Deafness

Objective:To analyze the efficacy of hyperbaric oxygen at different pressures in the treatment of sudden deafness.Methods:Eighty-two patients with sudden deafness treated in the Affiliated Hospital of Hebei University from September 2019 to September 2021 were selected as the research subjects.The patients were randomly divided into study group 1 and study group 2,and they were treated with hyperbaric oxygen on the basis of routine treatment,in which the pressure used was 1.8 ATA and 2.2 ATA,respectively.Oxygen was delivered via the pressure stabilizing mask for 60 minutes.The patients received two courses of treatment,each lasting 10 days.The changes in hearing(pure tone audiometry)and the clinical efficacy of both the groups were compared before and after treatment.The data obtained were statistically analyzed using SPSS 19.0.Results:The total effective rate of study group 1 was 90.00%,while that of study group 2 was 76.19%.The differences between the two groups were statistically significant(p<0.05).Conclusion:For patients with sudden deafness treated with hyperbaric oxygen,the clinical efficacy of 1.8 ATA is more significant than that of 2.2 ATA.

Observation on the Clinical Effect of Different Pressures in Hyperbaric Oxygen Therapy on Patients with Diffuse Axonal Injury

Objective:To observe the efficacy and significance of hyperbaric oxygen at different pressures in the treatment of diffuse axonal injury(DAI).Methods:Sixty patients with DAI were randomly divided into 1.8 ATA group(30 cases)and 2.2 ATA group(30 cases).The routine treatment for each group was the same.The 1.8 ATA.group received hyperbaric oxygen therapy under 1.8 ATA on the basis of routine treatment,whereas the 2.2 ATA group received hyperbaric oxygen therapy under 2.2 ATA.on the basis of routine treatment.The therapy was given once a day over 3 consecutive courses,with each course having 10 sessions.The Glasgow Coma Scale(GCS)on day 10,day 20,and day 30 after treatment,as well as the Glasgow Outcome Scale(GOS)after 6 months were compared between the two groups.Results:The mean GCS on day 10,day 20,and day 30 after treatment,as well as the mean GOS after 6 months of treatment in the 2.2 ATA group were significantly higher than those in the 1.8 ATA group(p<0.05).Conclusion:For patients with dififtise axonal injury,hyperbaric oxygen therapy is more effective with 2.2 ATA.compared with 1.8 ATA.

Characteristics of oxygen consumption of coal at programmed temperatures

Oxygen consumption is an important index of coal oxidation.In order to explore the coal-oxygen reaction,we developed an experimental system of coal spontaneous combustion and tested oxygen consumption of differently ranked coals at programmed temperatures.The size of coal samples ranged from 0.18~0.42 mm and the system heat-rate was 0.8℃/min.The results show that, for high ranked coals,oxygen consumption rises with coal temperature as a piecewise non-linear process.The critical coal temperature is about 50℃.Below this temperature,oxygen consumption decreases with rising coal temperatures and reached a minimum at 50℃,approximately.Subsequently,it begins to increase and the rate of growth clearly increased with temperature.For low ranked coals,this characteristic is inconspicuous or even non-existent.The difference in oxygen consumption at the same temperatures varies for differently ranked coals.The results show the difference in oxygen consumption of the coals tested in our study reached 78.6%at 100℃.Based on the theory of coal-oxygen reaction,these phenomena were analyzed from the point of view of physical and chemical characteristics,as well as the appearance of the coal-oxygen complex.From theoretical analyses and our experiments,we conclude that the oxygen consumption at programmed temperatures reflects the oxidation ability of coals perfectly.

Effects of high-volume hemofiltration on alveolar- arterial oxygen exchange in patients with refractory septic shock

BACKGROUND：High-volume hemofiltration （HVHF） is technically possible in severe acute pancreatitis （SAP） patients complicated with multiple organ dysfunction syndrome （MODS）. Continuous HVHF is expected to become a beneficial adjunct therapy for SAP complicated with MODS. In this study, we aimed to explore the effects of fluid resuscitation and HVHF on alveolar- arterial oxygen exchange, the Acute Physiology and Chronic Health Evaluation II （APACHE II） score in patients with refractory septic shock. METHODS：A total of 89 refractory septic shock patients, who were admitted to ICU, the Provincial Hospital affiliated to Shandong University from August 2006 to December 2009, were enrolled in this retrospective study. The patients were randomly divided into two groups： fluid resuscitation （group A, n=41）, and fluid resuscitation plus high-volume hemofiltration （group B, n=48）, The levels of O2 content of central venous blood （CcvO2）, arterial oxygen content （CaO2）, alveolar-arterial oxygen pressure difference P（A-a）DO2, ratio of arterial oxygen pressure/alveolar oxygen pressure （PaO2/ PAO2）, respiratory index （RI） and oxygenation index （OI） were determined. The oxygen exchange levels of the two groups were examined based on the arterial blood gas analysis at different times （0, 24, 72 hours and 7 days of treatment） in the two groups. The APACHE II score was calculated before and after 7-day treatment in the two groups. The levels of CcvO2, CaO2 on day 7 in group A were significantly lower than those in group B （CcvO2：0.60±0.24 vs, 0.72±0.28, P〈0.05; CaO2：0.84±0.43 vs. 0.94±0.46, P〈0.05）. The level of oxygen extraction rate （O2ER） in group A on the 7th day was significantly higher than that in group B （ 28.7±2.4 vs. 21.7±3.4, P〈0.01）. The levels of P（A-a）DO2 and RI in group B on the 7th day were significantly lower than those in group A. The levels of PaO2/PAO2 and OI in group B on 7th day were significantly higher than those in group A （P〈0.05 or P〈0.01）. The APACHE II score in the two groups reduced gradually after 7-day treatment, and the APACHE II score on the 7th day in group B was significantly lower than that in group A （8.2±3.8 vs. 17.2±6.8, P〈0.01）. HVHF combined with fluid resuscitation can improve alveolar- arterial-oxygen exchange, decrease the APACHE II score in patients with refractory septic shock, and thus it increases the survival rate of patients.

High room-temperature magnetization in Co-doped TiO_(2) nanoparticles promoted by vacuum annealing for different durations

To clarify the contribution of oxygen vacancies to room-temperature ferromagnetism(RTFM)in cobalt doped TiO_(2)(Co-TiO_(2)),and in order to obtain the high level of magnetization suitable for spintronic devices,in this work,Co-TiO_(2) nano-particles are prepared via the sol-gel route,followed by vacuum annealing for different durations,and the influence of vacu-um annealing duration on the structure and room-temperature magnetism of the compounds is examined.The results reveal that with an increase in annealing duration,the concentration of oxygen vacancies rises steadily,while the saturation magnetiza-tion(Ms)shows an initial gradual increase,followed by a sharp decline,and even disappearance.The maximum Ms is as high as 1.19 emu/g,which is promising with respect to the development of spintronic devices.Further analysis reveals that oxygen va-cancies,modulated by annealing duration,play a critical role in tuning room-temperature magnetism.An appropriate concentra-tion of oxygen vacancies is beneficial in terms of promoting RTFM in Co-TiO_(2).However,excessive oxygen vacancies will result in a negative impact on RTFM,due to antiferromagnetic superexchange interactions originating from nearest-neighbor Co^(2+)ions.

水产养殖中传统增氧设备增氧能力差异分析

为了解水产养殖中应用广泛的叶轮式增氧机、水车式增氧机、涌浪式增氧机和曝气式增氧机4种型式的增氧机的增氧性能水平,统计和分析了国内主要增氧设备生产企业2020年以来生产的145台不同型式增氧机的增氧能力试验数据。结果显示:1)部分企业生产的叶轮增氧机的增氧性能有所下降;2)水车式增氧机增氧性能有大幅提高,部分产品超过了SC/T 6010—2018《叶轮式增氧机通用技术条件》中规定同规格叶轮式增氧机的要求;3)涌浪式增氧机增氧性能总体呈上升趋势;4)曝气式增氧机具有较强的增氧性能,但配套风机形式不同、相同配套功率但曝气管不同的配置,其增氧性能存在较大差异。本研究为养殖用户在水产养殖系统增氧设备的配置时提供技术参考。

不同采后处理对恭城月柿褐变、活性氧代谢及糖类的影响

本文分析了有氧、真空和真空+1-MCP三种采后处理方式对脱涩后柿子贮藏过程中果实褐变、活性氧代谢和糖类的影响,并对褐变与各指标的相关性进行分析。真空和真空+1-MCP组柿子贮藏过程中的褐变指数BI低于有氧组,其中真空+1-MCP组褐变程度最低;三种采后处理柿子贮藏过程中SOD、APX活性分别呈下降和上升的趋势,真空组柿子SOD活性最低,真空和真空+1-MCP条件下柿子APX活性高于有氧组;真空和真空+1-MCP抑制柿子CAT活性的增加,减少H2O2积累,同时抑制羟自由基的能力和抗坏血酸含量较低。真空和真空+1-MCP组柿子还原糖含量低于有氧组,其中真空+1-MCP组增加最慢,从贮藏开始时的14.10%增加至12 d时的14.87%;真空+1-MCP组柿子果胶含量下降缓慢。相关性分析可知,不同采后处理柿子贮藏过程中柿子褐变与各指标的相关性并不相同,但柿子褐变指数BI均与果胶呈负相关,与还原糖呈正相关。综合可知真空和真空+1-MCP条件更有利于抑制脱涩后月柿的褐变。

中心静脉血氧饱和度联合静动脉二氧化碳分压差在产后出血液体复苏治疗中的指导作用

目的探讨中心静脉血氧饱和度(ScvO_(2))联合静动脉二氧化碳分压差[P(v-a)CO_(2)]在产后出血(PPH)液体复苏治疗中的指导作用。方法选取2022年2月至2023年3月江西省妇幼保健院收治的60例胎盘植入、前置胎盘剖宫产术中大出血患者作为研究对象,按照随机数字表法分成试验组(n=30)和对照组(n=30)。对照组行常规液体复苏干预,试验组行ScvO_(2)联合P(v-a)CO_(2)监测指标进行复苏干预。比较两组患者容量达标时间、液体复苏前后氧合指数、6 h乳酸清除率、24 h乳酸清除率及并发症发生率。结果试验组的容量达标时间短于对照组,差异有统计学意义(P<0.05);液体复苏6、24 h后试验组的氧合指数均高于对照组,差异有统计学意义(P<0.05);试验组6h乳酸清除率、24h乳酸清除率均高于对照组,差异有统计学意义(P<0.05);试验组的并发症总发生率(16.67%)低于对照组(40.00%),差异有统计学意义(P<0.05)。结论ScvO_(2)联合P(v-a)CO_(2)监测对PPH患者液体复苏治疗具有指导作用,能缩短液体复苏时间,提高氧合指数和乳酸清除率,降低并发症的发生。

不同角度俯卧位通气在急性呼吸窘迫综合征患者中的应用效果

目的评估不同角度俯卧位通气在急性呼吸窘迫综合征(ARDS)患者中的应用效果。方法本研究为一项前瞻性、随机、对照临床试验,纳入2021年7月至2023年6月广东省第二中医院重症医学科(ICU)收治的ARDS患者共96例,随机分为A组(0°俯卧位通气)、B组(30°俯卧位通气)、C组(45°俯卧位通气),每组32例。A组男19例,女13例;年龄(50.25±11.31)岁;体重指数(BMI)(23.42±3.16)kg/m^(2)。B组男17例,女15例;年龄(51.93±12.48)岁;BMI(22.72±4.15)kg/m^(2)。C组男20例,女12例;年龄(52.39±12.82)岁;BMI(24.76±4.31)kg/m^(2)。观察时间为5 d。A组患者每天持续0°俯卧位通气16 h,每2 h将其托起一次防止压力性损伤。B组:维持0°俯卧位2 h后,使用30°翻身垫将患者身体向左倾斜30°,维持2 h;然后向右倾斜30°,同样维持2 h;最后恢复至0°俯卧位,如此循环,直至完成16 h俯卧位通气。C组:维持0°俯卧位2 h后,使用45°翻身垫将患者身体向左倾斜45°,维持2 h;然后向右倾斜45°,同样维持2 h;最后恢复至0°俯卧位,如此循环,直至完成16 h俯卧位通气。比较3组氧合指标[氧合指数(PaO_(2)/FiO_(2))、动脉血氧饱和度(SaO_(2))、动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))]、血流动力学指标[心率(HR)、平均动脉压(MAP)、中心静脉压(CVP)]、Murray肺损伤评分(MLIS)、急性生理学及慢性健康状况评价Ⅱ(APACHEⅡ)评分、多器官功能障碍综合征(MODS)评分的变化,观察压力性损伤发生率。采用单因素方差分析、LSD法、配对t检验、χ^(2)检验。结果俯卧位通气5 d后,3组PaO_(2)/FiO_(2)、SaO_(2)、PaO_(2)、PaCO_(2)均较通气前改善,且A组、B组改善幅度均优于C组(均P<0.05);俯卧位通气前和通气5 d后,3组HR、MAP、CVP差异均无统计学意义(均P>0.05);俯卧位通气5 d后,3组MLIS、APACHEⅡ、MODS评分均较通气前降低,且A组、B组均低于C组[(1.72±0.37)分比(1.54±0.16)分比(1.89±0.26)分、(11.02±2.69)分比(11.01±2.01)分比(12.87±2.06)分、(5.64±0.37)分比(5.34±0.67)分比(6.19±0.43)分](均P<0.05);B组和C组压力性损伤发生率低于A组[15.63%(5/32)比18.75%(6/32)比40.63%(13/32)](P<0.05)。结论不同角度俯卧位通气均可以改善ARDS患者氧合和减轻病情,其中30°俯卧位通气改善最明显,并且可以降低压力性损伤发生率。

不同体质量虫纹鳕鲈对耗氧率、窒息点及排氨率的影响

开展了不同体质量虫纹鳕鲈对耗氧率、窒息点及排氨率的影响试验。采用密闭流水式呼吸试验法,测定了4种不同体质量[A组(100.3±5.8)g、B组(205.1±12.1)g、C组(298.5±17.2)g、D组(405.9±15.6)g]虫纹鳕鲈的耗氧率、窒息点及排氨率。结果表明,虫纹鳕鲈的耗氧率及排氨率,随其体质量的增加而降低;耗氧率日波动较大,每日的06:00—08:00与16:00—18:00处于高水平;窒息点随体质量的增加升高,且A组与D组之间差异显著(P<0.05)。提出,在实际生产中,可根据虫纹鳕鲈不同养殖阶段耗氧率、养殖密度及生物滤池总体耗氧率,测算液氧加入量,提高液氧利用率和循环水的养殖容量,增加养殖效益。

贮藏温度对核桃果实冷藏期青皮不同部位褐变、活性氧代谢和种仁品质的影响

核桃果实采后青皮极易发生褐变,目前有关不同温度贮藏核桃果实青皮不同部位的褐变差异及其原因未见报道。该文研究不同温度(0、2、5、8℃)贮藏对‘清香’核桃果实青皮不同部位外观、褐变指数、活性氧代谢及其种仁品质相关指标的影响。结果表明,贮藏期间核桃果实青皮的褐变程度随贮藏温度的升高而增加,0、2℃核桃果实青皮内部的褐变指数高于外部,5、8℃果实青皮内部的褐变指数低于外部;4种温度下果实青皮外部的过氧化物酶(peroxidase,POD)活性、多酚氧化酶(polyphenol oxidase,PPO)活性、总酚含量和过氧化氢(H2O2)含量均高于内部,超氧阴离子(·O2-)产生率和丙二醛(malondialdehyde,MDA)含量均低于内部;萼端褐变指数、·O2-产生率、可溶性总糖和游离脯氨酸含量高于梗端;0℃则更好地保持了果实的品质,延缓了种仁酸败,贮藏60 d时种仁的可溶性蛋白质和粗脂肪含量显著高于2℃果实。综合各项指标认为,核桃果实在0、2℃贮藏期为60 d,5、8℃贮藏期不足30 d;青皮的褐变可能是因其活性氧和MDA过量积累加重了膜脂过氧化作用所致。

原煤与氧化煤在不同氧气浓度下的氧化特性研究

通过自主研发的程序升温装置,以山东唐口烟煤为研究对象,分析了原煤与氧化煤在不同氧气浓度下的耗氧速率、放热强度、CO气体浓度、特征温度、交叉点温度的变化规律。结果表明,在21%氧气体积分数下,原煤的耗氧速率、放热强度均高于氧化煤,原煤的CO量反应初期小于氧化煤,后期大于氧化煤;在15%,10%氧气体积分数下,原煤的耗氧速度、放热强度低于氧化煤,氧化煤产生的CO量总高于原煤;在5%氧气体积分数下,原煤的耗氧速度、放热强度前期大于氧化煤,后期小于氧化煤,氧化煤产生的CO量总高于原煤。随着氧气体积分数的下降,原煤和氧化煤的特征温度都逐渐升高;在21%,15%氧气体积分数下,氧化煤的特征温度都低于原煤的特征温度,10%,5%氧气体积分数条件下原煤和氧化煤的临界温度和干裂温度相差不明显;随着氧气体积分数下降,原煤和氧化煤的交叉点温度都增大,且氧化煤的交叉点温度相较于原煤更提前。

亚低温联合高压氧对重型颅脑损伤患者神经功能、动脉-颈内静脉球部血氧差及预后的影响

目的探究亚低温联合高压氧(HBO)对重型颅脑损伤(STBI)患者神经功能、动脉-颈内静脉球部血氧差及预后的影响。方法选取2019年3月至2022年3月河北中医学院附属第二医院收治的STBI患者116例作为研究对象,将所有患者按随机数字表法分为HBO组和联合组,其中HBO组采用HBO空气加压舱进行治疗,联合组在HBO组的基础上联合亚低温治疗。采用酶联免疫吸附法检测中枢神经特异性蛋白(S-100B)和神经元特异性烯醇化酶(NSE)的水平;用美国卒中量表(NIHSS)对患者的神经功能缺损情况进行评估;血气分析仪测定患者的动脉氧含量(CaO_(2))和颈内静脉氧含量(CjvO_(2));用格拉斯哥结局量表(GOS)评估治疗效果;比较两组疗效、S-100B水平、NSE水平、NIHSS评分、Da-jvO_(2)、GOS评分的变化。结果联合组和HBO组的S-100B、NSE水平、NIHSS评分、Da-jvO_(2)在治疗后均降低;且治疗后联合组的S-100B、NSE水平、NIHSS评分、Da-jvO_(2)均低于HBO组;联合组治疗6个月后,预后良好的患者比例高于HBO组。结论亚低温联合HBO能有效改善重型颅脑损伤患者神经功能、Da-jvO_(2)及预后,效果显著。

外周灌注指数、血乳酸、中心静脉-动脉二氧化碳分压差与动脉-中心静脉氧含量差比值对脓毒症液体复苏预后的评估价值

目的探讨外周灌注指数(PI)、血乳酸(Lac)和中心静脉-动脉二氧化碳分压差与动脉-中心静脉氧含量差比值(Pv-aCO_(2)/Ca-vO_(2))对脓毒症液体复苏预后的评估价值。方法选取2021年7月至2022年12月江门市人民医院收治的82例脓毒症患者为研究对象,给予中心静脉导管进行液体复苏。根据患者28 d预后分为存活组58例和死亡组24例。比较两组患者复苏6 h后的PI、Lac、Pv-aCO_(2)/Ca-vO_(2)。采用受试者工作特征(ROC)曲线分析PI、Lac、Pv-aCO_(2)/Ca-vO_(2)对脓毒症液体复苏预后的评估价值。结果存活组复苏6 h后的PI高于死亡组,Lac、Pv-aCO_(2)/Ca-vO_(2)低于死亡组,差异有统计学意义(P<0.05)。PI、Lac、Pv-aCO_(2)/Ca-vO_(2)预测脓毒症液体复苏不良预后的灵敏度分别为66.67%、75.00%、79.17%,特异度分别为87.93%、86.21%、91.38%,截断值分别为0.350、4.625、1.720。联合预测的灵敏度为87.50%,特异度为94.83%(AUC=0.962)。结论PI、Lac、Pv-aCO_(2)/Ca-vO_(2)评估对脓毒症液体复苏治疗预后具有较好的预测价值。

基于差值法的不同氧浓度对煤自燃特性影响研究

煤低温氧化过程存在氧化、脱附和裂解等路径产生气体和热量,导致基于气体和热量获得的氧气浓度对煤氧复合反应动力学的影响不准确。提出一种能够消除这两条路径的方法,利用这种方法分别在不同氧浓度下通过程序升温实验研究不同煤的产气和产热特性,并结合X射线光电子能谱仪(XPS)和比表面积测试仪(BET)等微观表征,分析煤在氧化过程中发生微观变化的内在原因。实验结果表明,煤的比表面积及煤中含氧基团的含量对氧化产气浓度和初始产气温度具有较大影响,尤其是对于CO_(2)影响更大,采取差值的方法可以有效排除裂解和脱附的影响,获得能够反映煤氧复合本质特征的氧化路径;不同氧气浓度对氧化路径下产气和产热特性影响较大,随着氧气浓度的降低,产气浓度和产热速率逐渐降低,当氧气浓度低于6%时,初始产气温度明显升高,产热速率明显受到抑制,严重的抑制了煤与氧的进一步反应,从而很难发生煤自燃。

不同疗程高压氧治疗颅脑损伤患者的临床效果

目的观察不同疗程高压氧治疗对颅脑损伤患者的效果。方法选取山东第二医科大学附属益都中心医院2019年5月至2021年11月收治的80例颅脑损伤患者作为研究对象,按照随机数字表法分为试验组(40例)与对照组(40例)。在常规治疗的基础上,试验组加用高压氧治疗4疗程共60次,而对照组加用高压氧治疗2疗程共30次。经综合治疗80 d后,比较两组患者的临床总有效率、美国国立卫生研究院卒中量表评分(NIHSS)、日常生活活动能力量表评分(ADL)。结果试验组患者的临床治疗总有效率高于对照组,差异有统计学意义(P<0.01)。试验组患者治疗后的NIHSS评分低于对照组,ADL评分高于对照组,差异有统计学意义(P<0.05)。结论长疗程(>30次)高压氧治疗能更有效提高颅脑损伤患者神经功能、日常生活能力,值得临床推广。

城市高层建筑空气负离子浓度差异初探

随着我国城市化建设的发展,全国各地的高层建筑越来越多。为了了解城市高层建筑高低楼层之间空气负离子浓度(评判空气清新程度和人居环境的正向指标)的差异,指导社会各方面力量和人们更好地进行相关建设与投资,提高人民群众的健康水平,通过对高层建筑高低楼层的空气负离子浓度进行实际测量,发现该高层建筑高、低楼层的小时平均浓度分别在80、270个/cm^(3),高楼层和低楼层之间的空气负离子浓度存在明显的差异,低楼层浓度要远远高于高楼层浓度。分析了其存在的差异和原因,提出了楼顶绿化﹑室内绿化或使用负氧离子发生器等具体措施。

急性脑梗死病人的不同疗程高压氧治疗作用及对神经功能的影响

目的 探讨急性脑梗死病人的不同疗程高压氧治疗作用及对神经功能的影响。方法 选取2021年3月—2023年3月本院收治的80例急性脑梗死患者进行观察,应用随机数字表法分为对照组和实验组,每组40例。其中,对照组行常规治疗,实验组在对照组基础上加以高压氧治疗,治疗后比较两组临床效果。结果 实验组神经功能及日常生活活动能力改善情况均优于对照组(P<0.05),治疗总有效率高于对照组(P<0.05)。结论 高压氧治疗急性脑梗死的效果显著,随着疗程增加,患者神经功能及自理能力不断改善,依据患者病情予以不同疗程的治疗方案具有积极意义。