Taurine is considered a non-essential amino acid because it is synthesized by most mammals.However,dietary intake of taurine may be necessary to achieve the physiological levels required for the development,maintenanc...Taurine is considered a non-essential amino acid because it is synthesized by most mammals.However,dietary intake of taurine may be necessary to achieve the physiological levels required for the development,maintenance,and function of certain tissues.Taurine may be especially important for the retina.The concentration of taurine in the retina is higher than that in any other tissue in the body and taurine deficiency causes retinal oxidative stress,apoptosis,and degeneration of photoreceptors and retinal ganglion cells.Low plasma taurine levels may also underlie retinal degeneration in humans and therefore,taurine administration could exert retinal neuroprotective effects.Taurine has antioxidant,anti-apoptotic,immunomodulatory,and calcium homeostasis-regulatory properties.This review summarizes the role of taurine in retinal health and disease,where it appears that taurine may be a promising nutraceutical.展开更多
Taurine is a conditionally essential amino acid in fish nutrition.The present study addressed the practical application of examining published data on fish nutrition over the past 20 years,emphasizing the topic of tau...Taurine is a conditionally essential amino acid in fish nutrition.The present study addressed the practical application of examining published data on fish nutrition over the past 20 years,emphasizing the topic of taurine by using computational tools and their applications.According to the published articles,an increased linear growth of research occurred,with Japanese flounder being the most examined fish species.Dietary taurine supplementation has several beneficial effects in fish nutrition,such as survival,growth,feed utilization,protein and energy retention,intermediate metabolism,anti-oxidation,anti-stress,disease resistance,muscle texture and reproductive performance.Also,there are negative effects in some species.Dietary taurine exerted effects on several gene expressions and enzyme activities;these are important in taurine metabolism in fish.These genes and enzymes included taurine transporter(TauT),cysteine dioxygenase(CDO),cysteamine dioxygenase(ADO),cysteine sulfonate decarboxylase(CSD)and pretrypsinogen(Ptry).Plant protein-based diets with taurine supplementation are recommended because of the absence of taurine in plani protein.展开更多
基金supported by Instituto de Salud CarlosⅢ(ISCⅢ):PI19/00203cofunded by ERDF+9 种基金"A way to make Europe"to MPVP and DGAP122/00900RD16/0008/0026 co-funded by ERDF"A way to make Europe"to MPVP and RD21/0002/0014financiado porla Unión Europea-NextGenerationEUFundación Robles Chillida to DGARED2018-102499-TPID201 9-106498GB-I00funded by MCIN/AEI/10.13039/501100011 033 to MVSIHU FOReSIGHT[ANR-18-IAHU-0001] to SP
文摘Taurine is considered a non-essential amino acid because it is synthesized by most mammals.However,dietary intake of taurine may be necessary to achieve the physiological levels required for the development,maintenance,and function of certain tissues.Taurine may be especially important for the retina.The concentration of taurine in the retina is higher than that in any other tissue in the body and taurine deficiency causes retinal oxidative stress,apoptosis,and degeneration of photoreceptors and retinal ganglion cells.Low plasma taurine levels may also underlie retinal degeneration in humans and therefore,taurine administration could exert retinal neuroprotective effects.Taurine has antioxidant,anti-apoptotic,immunomodulatory,and calcium homeostasis-regulatory properties.This review summarizes the role of taurine in retinal health and disease,where it appears that taurine may be a promising nutraceutical.
基金Ack no wledgements This study was financially supported by the National Key R&D Program of China(2019YFD0900200)the Key R&D Program of Shandong Province,China(2016CYJS04A01,2017CXGC0105).
文摘Taurine is a conditionally essential amino acid in fish nutrition.The present study addressed the practical application of examining published data on fish nutrition over the past 20 years,emphasizing the topic of taurine by using computational tools and their applications.According to the published articles,an increased linear growth of research occurred,with Japanese flounder being the most examined fish species.Dietary taurine supplementation has several beneficial effects in fish nutrition,such as survival,growth,feed utilization,protein and energy retention,intermediate metabolism,anti-oxidation,anti-stress,disease resistance,muscle texture and reproductive performance.Also,there are negative effects in some species.Dietary taurine exerted effects on several gene expressions and enzyme activities;these are important in taurine metabolism in fish.These genes and enzymes included taurine transporter(TauT),cysteine dioxygenase(CDO),cysteamine dioxygenase(ADO),cysteine sulfonate decarboxylase(CSD)and pretrypsinogen(Ptry).Plant protein-based diets with taurine supplementation are recommended because of the absence of taurine in plani protein.
