Two classes of rate controlling medications—beta blockers (BBs) and non- dihydropyridine calcium channel blockers (CCBs)—are given to patients who present with atrial fibrillation (AF) with rapid ventricular respons...Two classes of rate controlling medications—beta blockers (BBs) and non- dihydropyridine calcium channel blockers (CCBs)—are given to patients who present with atrial fibrillation (AF) with rapid ventricular response (RVR). Both are Class I recommendations from the American Heart Association (AHA), American College of Cardiology (ACC), and Heart Rhythm Society (HRS) for the management of AF with RVR. Multiple studies support the view that diltiazem is more effective than metoprolol, even though data from the AFFIRM trial suggests BBs are more frequently used. CCBs are generally avoided in AF with RVR patients who have concomitant heart failure with reduced ejection fraction (HFrEF) for concern of triggering decompensation. However, some recent studies indicate this idea may be unfounded. The aim of this article is to compare the efficacy of diltiazem and metoprolol for rate control in AF with RVR and examine the use of diltiazem in patients with both AF with RVR and HFrEF.展开更多
目的探讨持续性心房颤动(房颤)患者射频消融术后左房功能变化趋势及其与炎症的关系。方法选择2021年1月至2021年11月就诊于安徽医科大学附属阜阳人民医院心血管内科的80例持续性房颤患者,行血常规及常规超声检查和四维自动左心房定量分...目的探讨持续性心房颤动(房颤)患者射频消融术后左房功能变化趋势及其与炎症的关系。方法选择2021年1月至2021年11月就诊于安徽医科大学附属阜阳人民医院心血管内科的80例持续性房颤患者,行血常规及常规超声检查和四维自动左心房定量分析技术(4D Auto LAQ)分析,获取心房收缩期前容积、左心房最大容积、左心房最大容积指数、左心房最小容积、左心房前后径、左心房射血分数、左房四维应变参数、白细胞总数(WBC)、超敏C反应蛋白(hs-CRP),分析左心房功能变化趋势及其与炎症指标的关系。结果左心房最大容积于术后呈逐渐下降趋势。左心房最大容积指数、左心房最小容积、左心房收缩期前容积、左心房前后径、左心房射血分数、左房四维应变参数在术后1周内较术前明显下降,随后缓慢增加,在术后1个月左右恢复至术前水平,在术后3个月时较术前明显改善。WBC、hs-CRP均在房颤射频消融术后在术后第7 d明显下降,在随后的随访各时间段内逐渐降至正常,且其变化与左房功能变化存在相关性。结论持续性房颤患者射频消融术后左房功能在1个月内存在短暂的恶化期,术后3个月较术前明显改善,且其变化与炎症因子存在相关性。展开更多
文摘Two classes of rate controlling medications—beta blockers (BBs) and non- dihydropyridine calcium channel blockers (CCBs)—are given to patients who present with atrial fibrillation (AF) with rapid ventricular response (RVR). Both are Class I recommendations from the American Heart Association (AHA), American College of Cardiology (ACC), and Heart Rhythm Society (HRS) for the management of AF with RVR. Multiple studies support the view that diltiazem is more effective than metoprolol, even though data from the AFFIRM trial suggests BBs are more frequently used. CCBs are generally avoided in AF with RVR patients who have concomitant heart failure with reduced ejection fraction (HFrEF) for concern of triggering decompensation. However, some recent studies indicate this idea may be unfounded. The aim of this article is to compare the efficacy of diltiazem and metoprolol for rate control in AF with RVR and examine the use of diltiazem in patients with both AF with RVR and HFrEF.
文摘目的探讨持续性心房颤动(房颤)患者射频消融术后左房功能变化趋势及其与炎症的关系。方法选择2021年1月至2021年11月就诊于安徽医科大学附属阜阳人民医院心血管内科的80例持续性房颤患者,行血常规及常规超声检查和四维自动左心房定量分析技术(4D Auto LAQ)分析,获取心房收缩期前容积、左心房最大容积、左心房最大容积指数、左心房最小容积、左心房前后径、左心房射血分数、左房四维应变参数、白细胞总数(WBC)、超敏C反应蛋白(hs-CRP),分析左心房功能变化趋势及其与炎症指标的关系。结果左心房最大容积于术后呈逐渐下降趋势。左心房最大容积指数、左心房最小容积、左心房收缩期前容积、左心房前后径、左心房射血分数、左房四维应变参数在术后1周内较术前明显下降,随后缓慢增加,在术后1个月左右恢复至术前水平,在术后3个月时较术前明显改善。WBC、hs-CRP均在房颤射频消融术后在术后第7 d明显下降,在随后的随访各时间段内逐渐降至正常,且其变化与左房功能变化存在相关性。结论持续性房颤患者射频消融术后左房功能在1个月内存在短暂的恶化期,术后3个月较术前明显改善,且其变化与炎症因子存在相关性。
