Alzheimer’s disease(AD)is broadly defined by dementia and the presence of specific neuropathological features in the brain(amyloid plaques,neurofibrillary tangles(NFTs)and congophilic amyloid angiopathy).Howeve...Alzheimer’s disease(AD)is broadly defined by dementia and the presence of specific neuropathological features in the brain(amyloid plaques,neurofibrillary tangles(NFTs)and congophilic amyloid angiopathy).However,the rate of disease progression,type of cognitive impairment,and extent of neuropathology vary widely in patients with AD(Murray et al.,2011).展开更多
Relevance of Alzheimer’s disease(AD):AD is one of the greatest health-care challenges of the 21^st century.It is known to be the most common neurodegenerative disease and,in the United States,the sixth most common...Relevance of Alzheimer’s disease(AD):AD is one of the greatest health-care challenges of the 21^st century.It is known to be the most common neurodegenerative disease and,in the United States,the sixth most common cause of death.展开更多
文摘Alzheimer’s disease(AD)is broadly defined by dementia and the presence of specific neuropathological features in the brain(amyloid plaques,neurofibrillary tangles(NFTs)and congophilic amyloid angiopathy).However,the rate of disease progression,type of cognitive impairment,and extent of neuropathology vary widely in patients with AD(Murray et al.,2011).
文摘Relevance of Alzheimer’s disease(AD):AD is one of the greatest health-care challenges of the 21^st century.It is known to be the most common neurodegenerative disease and,in the United States,the sixth most common cause of death.