BACKGROUND Uterine fibroids are common benign gynecological conditions.Patients who experience excessive menstruation,anemia,and pressure symptoms should be administered medication,and severe cases require a total hys...BACKGROUND Uterine fibroids are common benign gynecological conditions.Patients who experience excessive menstruation,anemia,and pressure symptoms should be administered medication,and severe cases require a total hysterectomy.This procedure is invasive and causes severe postoperative pain,which can affect the patient’s postoperative sleep quality and,thus,the recovery process.AIM To evaluate use of dezocine in patient-controlled epidural analgesia(PCEA)for postoperative pain management in patients undergoing total myomectomy.METHODS We selected 100 patients undergoing total abdominal hysterectomy for uterine fibroids and randomized them into two groups:A control group receiving 0.2%ropivacaine plus 0.06 mg/mL of morphine and an observation group receiving 0.2%ropivacaine plus 0.3 mg/mL of diazoxide in their PCEA.Outcomes assessed included pain levels,sedation,recovery indices,PCEA usage,stress factors,and sleep quality.RESULTS The observation group showed lower visual analog scale scores,shorter postoperative recovery indices,fewer mean PCEA compressions,lower cortisol and blood glucose levels,and better polysomnographic parameters compared to the control group(P<0.05).The cumulative incidence of adverse reactions was lower in the observation group than in the control group(P<0.05).CONCLUSION Dezocine PCEA can effectively control the pain associated with total myomectomy,reduce the negative impact of stress factors,and have less impact on patients’sleep,consequently resulting in fewer adverse effects.展开更多
目的探讨不同剂量轻比重丁哌卡因蛛网膜下腔麻醉在高龄患者髋关节骨折手术中的应用效果。方法选取60例行髋关节骨折手术的高龄患者,随机分成A组、B组、C组,每组20例。3组患者分别采用1.4 mL 0.25%轻比重丁哌卡因、1.8 mL 0.25%轻比重丁...目的探讨不同剂量轻比重丁哌卡因蛛网膜下腔麻醉在高龄患者髋关节骨折手术中的应用效果。方法选取60例行髋关节骨折手术的高龄患者,随机分成A组、B组、C组,每组20例。3组患者分别采用1.4 mL 0.25%轻比重丁哌卡因、1.8 mL 0.25%轻比重丁哌卡因、2.2 mL 0.25%轻比重丁哌卡因进行蛛网膜下腔麻醉。比较3组患者的感觉神经及运动神经阻滞起效时间、持续时间,以及麻醉后15 min手术侧单侧阻滞发生率、术中追加局麻药的比例及给药后48 h内不良反应发生情况。结果 3组患者感觉神经阻滞起效时间、运动神经阻滞起效时间及麻醉后15 min术侧单侧阻滞发生率差异均无统计学意义(P均>0.05),而3组患者感觉神经阻滞持续时间和运动神经阻滞持续时间均为C组>B组>A组(均P<0.05)。A组术中追加硬膜外麻醉药的比例均高于B组与C组(均P<0.05),而B组与C组之间差异无统计学意义(P>0.05);C组术中低血压发生率高于B组(P<0.05),而A组与B组之间差异无统计学意义(P>0.05);3组患者均无寒战和术后头痛发生,且心动过缓、恶心呕吐及术后腰背痛发生率均无统计学差异(均P>0.05)。结论在高龄患者髋关节骨折手术中采用1.8 mL 0.25%轻比重丁哌卡因腰麻液进行蛛网膜下腔麻醉,可获得满意的麻醉效果,保持血流动力学稳定,且不良反应少。展开更多
基金Natural Science Foundation of Gansu Provincial Science and Technology Department(Basic Research Program),No.23JRRA1385.
文摘BACKGROUND Uterine fibroids are common benign gynecological conditions.Patients who experience excessive menstruation,anemia,and pressure symptoms should be administered medication,and severe cases require a total hysterectomy.This procedure is invasive and causes severe postoperative pain,which can affect the patient’s postoperative sleep quality and,thus,the recovery process.AIM To evaluate use of dezocine in patient-controlled epidural analgesia(PCEA)for postoperative pain management in patients undergoing total myomectomy.METHODS We selected 100 patients undergoing total abdominal hysterectomy for uterine fibroids and randomized them into two groups:A control group receiving 0.2%ropivacaine plus 0.06 mg/mL of morphine and an observation group receiving 0.2%ropivacaine plus 0.3 mg/mL of diazoxide in their PCEA.Outcomes assessed included pain levels,sedation,recovery indices,PCEA usage,stress factors,and sleep quality.RESULTS The observation group showed lower visual analog scale scores,shorter postoperative recovery indices,fewer mean PCEA compressions,lower cortisol and blood glucose levels,and better polysomnographic parameters compared to the control group(P<0.05).The cumulative incidence of adverse reactions was lower in the observation group than in the control group(P<0.05).CONCLUSION Dezocine PCEA can effectively control the pain associated with total myomectomy,reduce the negative impact of stress factors,and have less impact on patients’sleep,consequently resulting in fewer adverse effects.
文摘目的探讨不同剂量轻比重丁哌卡因蛛网膜下腔麻醉在高龄患者髋关节骨折手术中的应用效果。方法选取60例行髋关节骨折手术的高龄患者,随机分成A组、B组、C组,每组20例。3组患者分别采用1.4 mL 0.25%轻比重丁哌卡因、1.8 mL 0.25%轻比重丁哌卡因、2.2 mL 0.25%轻比重丁哌卡因进行蛛网膜下腔麻醉。比较3组患者的感觉神经及运动神经阻滞起效时间、持续时间,以及麻醉后15 min手术侧单侧阻滞发生率、术中追加局麻药的比例及给药后48 h内不良反应发生情况。结果 3组患者感觉神经阻滞起效时间、运动神经阻滞起效时间及麻醉后15 min术侧单侧阻滞发生率差异均无统计学意义(P均>0.05),而3组患者感觉神经阻滞持续时间和运动神经阻滞持续时间均为C组>B组>A组(均P<0.05)。A组术中追加硬膜外麻醉药的比例均高于B组与C组(均P<0.05),而B组与C组之间差异无统计学意义(P>0.05);C组术中低血压发生率高于B组(P<0.05),而A组与B组之间差异无统计学意义(P>0.05);3组患者均无寒战和术后头痛发生,且心动过缓、恶心呕吐及术后腰背痛发生率均无统计学差异(均P>0.05)。结论在高龄患者髋关节骨折手术中采用1.8 mL 0.25%轻比重丁哌卡因腰麻液进行蛛网膜下腔麻醉,可获得满意的麻醉效果,保持血流动力学稳定,且不良反应少。
