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Decoupling of temporal/spatial broadening effects in Doppler wind LiDAR by 2D spectral analysis
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作者 刘珍 张云鹏 +3 位作者 竹孝鹏 刘继桥 毕德仓 陈卫标 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期447-452,共6页
Pulse echo accumulation is commonly employed in coherent Doppler wind LiDAR(light detection and ranging)under the assumption of steady wind.Here,the measured spectral data are analyzed in the time dimension and freque... Pulse echo accumulation is commonly employed in coherent Doppler wind LiDAR(light detection and ranging)under the assumption of steady wind.Here,the measured spectral data are analyzed in the time dimension and frequency dimension to cope with the temporal wind shear and achieve the optimal accumulation time.A hardware-efficient algorithm combining the interpolation and cross-correlation is used to enhance the wind retrieval accuracy by reducing the frequency sampling interval and then reduce the spectral width calculation error.Moreover,the temporal broadening effect and spatial broadening effect are decoupled according to the strategy we developed. 展开更多
关键词 Doppler wind LiDAR spectral analysis hardware efficiency spectrum broadening effects
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A Study of the Teaching Effects of Case Analysis in Cross-Cultural Communication Class-Taking Individualism-Collectivism Cultural Dimension Class as an Example
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作者 ZHOU Qingyan 《Sino-US English Teaching》 2024年第8期372-376,共5页
This study introduces the individualism-collectivism dimension of the cultural dimension of cross-cultural communication initiated by Geert Hofstede.Different cultures must develop a way of correlating that strikes a ... This study introduces the individualism-collectivism dimension of the cultural dimension of cross-cultural communication initiated by Geert Hofstede.Different cultures must develop a way of correlating that strikes a balance between caring for themselves and showing concern for others.Individualist culture encourages uniqueness and independence while collectivist culture emphasizes conformity and mutual assistance.This article introduces how to use case analysis method to effectively carry out classroom teaching in this cultural dimension. 展开更多
关键词 cultural dimension case analysis cross cultural communication teaching effects
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Geospatial Analysis of Urban Heat Island Effects and Tree Equity
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作者 Jillian Gorrell Sharon R. Jean-Philippe +3 位作者 Paul D. Ries Jennifer K. Richards Neelam C. Poudyal Rochelle Butler 《Open Journal of Forestry》 2024年第1期1-18,共18页
In recent decades, Urban Heat Island Effects have become more pronounced and more widely examined. Despite great technological advances, our current societies still experience great spatial disparity in urban forest a... In recent decades, Urban Heat Island Effects have become more pronounced and more widely examined. Despite great technological advances, our current societies still experience great spatial disparity in urban forest access. Urban Heat Island Effects are measurable phenomenon that are being experienced by the world’s most urbanized areas, including increased summer high temperatures and lower evapotranspiration from having impervious surfaces instead of vegetation and trees. Tree canopy cover is our natural mitigation tool that absorbs sunlight for photosynthesis, protects humans from incoming radiation, and releases cooling moisture into the air. Unfortunately, urban areas typically have low levels of vegetation. Vulnerable urban communities are lower-income areas of inner cities with less access to heat protection like air conditioners. This study uses mean evapotranspiration levels to assess the variability of urban heat island effects across the state of Tennessee. Results show that increased developed land surface cover in Tennessee creates measurable changes in atmospheric evapotranspiration. As a result, the mean evapotranspiration levels in areas with less tree vegetation are significantly lower than the surrounding forested areas. Central areas of urban cities in Tennessee had lower mean evapotranspiration recordings than surrounding areas with less development. This work demonstrates the need for increased tree canopy coverage. 展开更多
关键词 Spatial analysis Land Cover Urban Heat Island effect (UHIE) EVAPOTRANSPIRATION Tree Canopy Impervious Surface GIS Prediction Model GIS Machine Learning
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Systematic analysis and modeling of the FLASH sparing effect as a function of dose and dose rate
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作者 Qi-Bin Fu Yan Zhang +3 位作者 Yu-Cheng Wang Tu-Chen Huang Hong-Yu Zhu Xiao-Wu Deng 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第10期51-58,共8页
Ultrahigh-dose-rate radiotherapy(FLASH-RT)is a revolutionary radiotherapy technology that can spare normal tissues without compromising tumor control.Although qualitative experimental results have been reported,quanti... Ultrahigh-dose-rate radiotherapy(FLASH-RT)is a revolutionary radiotherapy technology that can spare normal tissues without compromising tumor control.Although qualitative experimental results have been reported,quantitative and systematic analysis of data is necessary.Particularly,the FLASH effect response model to the dose or dose rate is still unclear.This study investigated the relationships between the FLASH effect and experimental parameters,such as dose,dose rate,and other factors by analyzing published in vivo experimental data from animal models.The data were modeled based on logistic regression analysis using the sigmoid function.The model was evaluated using prediction accuracy,receiver operating characteristic(ROC)curve,and area under the ROC curve.Results showed that the FLASH effect was closely related to the dose,mean dose rate,tissue type,and corresponding biological endpoints.The dose rate corresponding to a 50% probability of triggering cognitive protection in the brain was 45 Gy s^(-1).The dose rate corresponding to a 50% probability of triggering intestinal crypt survival and regeneration was 140 Gy s^(-1).For the skin toxicity effect,the dose corresponding to a 50% probability of triggering the FLASH effect was 24 Gy.This study helps to characterize the conditions underlying the FLASH effect and provides important information for optimizing experiments. 展开更多
关键词 FLASH radiotherapy Sparing effect Systematic analysis Dose rate DOSE Biological endpoints
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Effect of boundary conditions on shakedown analysis of heterogeneous materials
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作者 Xiuchen GONG Yinghao NIE +1 位作者 Gengdong CHENG Kai LI 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第1期39-68,共30页
The determination of the ultimate load-bearing capacity of structures made of elastoplastic heterogeneous materials under varying loads is of great importance for engineering analysis and design. Therefore, it is nece... The determination of the ultimate load-bearing capacity of structures made of elastoplastic heterogeneous materials under varying loads is of great importance for engineering analysis and design. Therefore, it is necessary to accurately predict the shakedown domains of these materials. The static shakedown theorem, also known as Melan's theorem, is a fundamental method used to predict the shakedown domains of structures and materials. Within this method, a key aspect lies in the construction and application of an appropriate self-equilibrium stress field(SSF). In the structural shakedown analysis, the SSF is typically constructed by governing equations that satisfy no external force(NEF) boundary conditions. However, we discover that directly applying these governing equations is not suitable for the shakedown analysis of heterogeneous materials. Researchers must consider the requirements imposed by the Hill-Mandel condition for boundary conditions and the physical significance of representative volume elements(RVEs). This paper addresses this issue and demonstrates that the sizes of SSFs vary under different boundary conditions, such as uniform displacement boundary conditions(DBCs), uniform traction boundary conditions(TBCs), and periodic boundary conditions(PBCs). As a result, significant discrepancies arise in the predicted shakedown domain sizes of heterogeneous materials. Built on the demonstrated relationship between SSFs under different boundary conditions, this study explores the conservative relationships among different shakedown domains, and provides proof of the relationship between the elastic limit(EL) factors and the shakedown loading factors under the loading domain of two load vertices. By utilizing numerical examples, we highlight the conservatism present in certain results reported in the existing literature. Among the investigated boundary conditions, the obtained shakedown domain is the most conservative under TBCs.Conversely, utilizing PBCs to construct an SSF for the shakedown analysis leads to less conservative lower bounds, indicating that PBCs should be employed as the preferred boundary conditions for the shakedown analysis of heterogeneous materials. 展开更多
关键词 heterogeneous material self-equilibrium stress field(SSF) shakedown analysis effect of boundary conditions
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Analysis of the Effect of Humanistic Care in the Process of Pre-Hospital Emergency Care
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作者 Rui Cao Zhe Chen 《Journal of Clinical and Nursing Research》 2024年第8期302-305,共4页
Objective:To explore the effectiveness of humanistic care in pre-hospital emergency care.Methods:From April 2020 to January 2021,80 pre-hospital emergency patients were studied.The patients were randomly divided into ... Objective:To explore the effectiveness of humanistic care in pre-hospital emergency care.Methods:From April 2020 to January 2021,80 pre-hospital emergency patients were studied.The patients were randomly divided into two groups:a control group(n=40),which received conventional care,and an experimental group(n=40),which received humanistic care.The effects of nursing care and psychological state were compared between the two groups.Results:The experimental group showed better nursing outcomes and a more positive psychological state compared to the control group(P<0.05).Conclusion:Humanistic care in pre-hospital emergency settings is more effective in reducing patients’anxiety and depression,enhancing the operational abilities and service attitudes of nursing staff,and increasing the emergency success rate. 展开更多
关键词 Humanistic care Pre-hospital emergency care Negative emotion effect analysis
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Histological Assessment and Transcriptome Analysis Provide Insights into the Toxic Effects of Perfluorooctanoic Acid to Juvenile Half Smooth Tongue Sole Cynoglossus semilaevis
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作者 ZHAN Min SHI Kunpeng +7 位作者 ZHANG Xue FAN Qingxin XU Qian LIU Xinbao LI Zhujun LIU Hongning XIA Yanting SHA Zhenxia 《Journal of Ocean University of China》 SCIE CAS CSCD 2023年第6期1635-1648,共14页
Perfluorooctanoic acid(PFOA)is a widespread synthetic persistent organic pollutant that may enrich along the food chain and affect the growth,development,reproduction,and lipid metabolism of aquatic organisms,particul... Perfluorooctanoic acid(PFOA)is a widespread synthetic persistent organic pollutant that may enrich along the food chain and affect the growth,development,reproduction,and lipid metabolism of aquatic organisms,particularly the benthic organisms.How-ever,the toxic effects of PFOA on the half-smooth tongue sole Cynoglossus semilaevis,a commercial benthic fish in China,have rarely been reported.Because juvenile fish are sensitive to environmental pollutants,in the present study,histological assessment and tran-scriptome sequencing were performed to determine the short-term impact of PFOA on juvenile half-smooth tongue soles.Histologi-cal analysis showed that PFOA exposure caused hepatocyte rupture,intestinal villi breakage,increased goblet cell count,and brain ab-normal.Transcriptome results showed that some interesting signaling pathways,such as glycolysis/gluconeogenesis,PPAR signaling pathway and GABAergic synapse signaling pathway,were enriched after PFOA exposure.In addition,some metabolic,immune and neural genes were differentially expressed,which including ependymin,hbb1-like and gad 1,and they were up-regulated after 14 days of exposure.Transcriptome results also indicated that half-smooth tongue sole might improve energy metabolism in response to PFOA toxicity after 7 days of exposure.These findings provide a basis for studying the ecological effects of PFOA on marine benthic fishes. 展开更多
关键词 Cynoglossus semilaevis histological assessment perfluorooctanoic acid transcriptome analysis toxic effect
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Neighborhood Effects and Political Trust: A Multi-level Analysis of Chinese Rural-to-Urban Migrants’ Trust in County Government
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作者 Chen Zhang 《Management Studies》 2023年第3期105-124,共20页
Massive rural-to-urban migration in China is consequential for political trust: rural-to-urban migrants have been found to hold lower levels of trust in local government than their rural peers who choose to stay in th... Massive rural-to-urban migration in China is consequential for political trust: rural-to-urban migrants have been found to hold lower levels of trust in local government than their rural peers who choose to stay in the countryside (mean 4.92 and 6.34 out of 10, respectively, p < 0.001). This article explores why migrants have a certain level of political trust in their county-level government. Using data of rural-to-urban migrants from the China Family Panel Survey, this study performs a hierarchical linear modeling (HLM) to unpack the multi-level explanatory factors of rural-to-urban migrants’ political trust. Findings show that the individual-level socio-economic characteristics and perceptions of government performance (Level-1), the neighborhood-level characteristics-the physical and social status and environment of neighborhoods (Level-2), and the objective macroeconomic performance of county-level government (Level-3), work together to explain migrants’ trust levels. These results suggest that considering the effects of neighborhood-level factors on rural-to-urban migrants’ political trust merits policy and public management attention in rapidly urbanizing countries. 展开更多
关键词 rural-to-urban migrants multi-level analysis neighborhood effects political trust hierarchical linear modeling China
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Causal Analysis Between Rice Growth and Cadmium Accumulation and Transfer under Arbuscular Mycorrhizal Inoculation 被引量:2
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作者 ZHAO Ting WANG Li +1 位作者 YANG Jixian MA Fang 《Rice science》 SCIE CSCD 2024年第2期226-236,共11页
Cadmium(Cd)contamination in rice has been a serious threat to human health.To investigate the effects of arbuscular mycorrhizal fungi(AMF)on the Cd translocation in rice,a controlled pot experiment was conducted.The r... Cadmium(Cd)contamination in rice has been a serious threat to human health.To investigate the effects of arbuscular mycorrhizal fungi(AMF)on the Cd translocation in rice,a controlled pot experiment was conducted.The results indicated that AMF significantly increased rice biomass,with an increase of up to 40.0%,particularly in root biomass by up to 68.4%.Notably,the number of prominent rice individuals also increased,and their plasticity was enhanced following AMF inoculation.AMF led to an increase in the net photosynthetic rate and antioxidant enzyme activity of rice.In the AMF treatment group,the Cd concentration in the rice roots was significantly higher(19.1%‒68.0%)compared with that in the control group.Conversely,the Cd concentration in the rice seeds was lower in the AMF treatment group,indicating that AMF facilitated the sequestration of Cd in rice roots and reduced Cd accumulation in the seeds.Path coefficients varied across different treatments,suggesting that AMF inoculation reduced the direct impact of soil Cd concentration on the total Cd accumulation in seeds.The translocation of Cd was consistently associated with simultaneous growth dilution and compensatory accumulation as a result of mycorrhizal effects.Our study quantitatively analyzed this process through path analysis and clarified the causal relationship between rice growth and Cd transfer under the influence of AMF. 展开更多
关键词 cadmium transfer dilution effect heavy metal immobilization mycorrhizal effect path analysis phenotypic plasticity
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Semi-analytical solution for drained expansion analysis of a hollow cylinder of critical state soils 被引量:1
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作者 He Yang Jialiang Zhang +1 位作者 Haisui Yu Peizhi Zhuang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2326-2340,共15页
The expansion of a thick-walled hollow cylinder in soil is of non-self-similar nature that the stress/deformation paths are not the same for different soil material points.As a result,this problem cannot be solved by ... The expansion of a thick-walled hollow cylinder in soil is of non-self-similar nature that the stress/deformation paths are not the same for different soil material points.As a result,this problem cannot be solved by the common self-similar-based similarity techniques.This paper proposes a novel,exact solution for rigorous drained expansion analysis of a hollow cylinder of critical state soils.Considering stress-dependent elastic moduli of soils,new analytical stress and displacement solutions for the nonself-similar problem are developed taking the small strain assumption in the elastic zone.In the plastic zone,the cavity expansion response is formulated into a set of first-order partial differential equations(PDEs)with the combination use of Eulerian and Lagrangian descriptions,and a novel solution algorithm is developed to efficiently solve this complex boundary value problem.The solution is presented in a general form and thus can be useful for a wide range of soils.With the new solution,the non-self-similar nature induced by the finite outer boundary is clearly demonstrated and highlighted,which is found to be greatly different to the behaviour of cavity expansion in infinite soil mass.The present solution may serve as a benchmark for verifying the performance of advanced numerical techniques with critical state soil models and be used to capture the finite boundary effect for pressuremeter tests in small-sized calibration chambers. 展开更多
关键词 Cavity expansion Drained analysis Boundary effect Critical state soil Non-self-similar Eulerian-Lagrangian approach
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Enhancing wood efficiency through comprehensive wood flow analysis:Methodology and strategic insights
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作者 Ruisheng Wang Peer Haller 《Forest Ecosystems》 SCIE CSCD 2024年第2期172-183,共12页
Wood,an essential natural resource in human civilization,remains widely used despite advances in technology and material substitution.The surge in greenhouse gas emissions and environmental concerns accentuates the ne... Wood,an essential natural resource in human civilization,remains widely used despite advances in technology and material substitution.The surge in greenhouse gas emissions and environmental concerns accentuates the need for optimizing wood utilization.Material flow analysis is a powerful tool for tracking material flows and stocks,aiding resource management and environmental decision-making.However,the full extent of its methodological dimensions,particularly within the context of the wood supply chain,remains relatively unexplored.In this study,we delve into the existing literature on wood flow analysis,discussing its primary objectives,materials involved,temporal and spatial scales,data sources,units,and conversion factors.Additionally,data uncertainty,data reconciliation and crucial assumptions in material flow analysis are highlighted in this paper.Key findings reveal the significance of wood cascading and substitution effects by replacing non-wood materials,where they can reduce greenhouse gas emissions more than the natural carbon sink of forests and wood products.The immediate impact of short-term wood cascading might not be as robust as the substitution effect,with energy substitution showcasing better results than material substitution.However,it's crucial to note that these conclusions could experience significant reversal from a long-term and global perspective.Strategies for improving wood efficiency involve maximizing material use,advancing construction technologies,extending product lifespans,promoting cascade use,and optimizing energy recovery processes.The study underscores the need for standardized approaches in wood flow analysis and emphasizes the potential of wood efficiency strategies in addressing environmental challenges. 展开更多
关键词 Material flow analysis WOOD METHODOLOGY Cascade use Substitution effects
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Modeling Analysis of Factors Influencing Wind-Borne Seed Dispersal: A Case Study on Dandelion
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作者 Kemeng Xue 《American Journal of Plant Sciences》 CAS 2024年第4期252-267,共16页
A weed is a plant that thrives in areas of human disturbance, such as gardens, fields, pastures, waysides, and waste places where it is not intentionally cultivated. Dispersal affects community dynamics and vegetation... A weed is a plant that thrives in areas of human disturbance, such as gardens, fields, pastures, waysides, and waste places where it is not intentionally cultivated. Dispersal affects community dynamics and vegetation response to global change. The process of seed disposal is influenced by wind, which plays a crucial role in determining the distance and probability of seed dispersal. Existing models of seed dispersal consider wind direction but fail to incorporate wind intensity. In this paper, a novel seed disposal model was proposed in this paper, incorporating wind intensity based on relevant references. According to various climatic conditions, including temperate, arid, and tropical regions, three specific regions were selected to establish a wind dispersal model that accurately reflects the density function distribution of dispersal distance. Additionally, dandelions growth is influenced by a multitude of factors, encompassing temperature, humidity, climate, and various environmental variables that necessitate meticulous consideration. Based on Factor Analysis model, which completely considers temperature, precipitation, solar radiation, wind, and land carrying capacity, a conclusion is presented, indicating that the growth of seeds is primarily influenced by plant attributes and climate conditions, with the former exerting a relatively stronger impact. Subsequently, the remaining two plants were chosen based on seed weight, yielding consistent conclusion. 展开更多
关键词 Seed Dispersal Wind Intensity Climatic effect Factor analysis Model
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Quantitative Analysis of Seeing with Height and Time at Muztagh-Ata Site Based on ERA5 Database
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作者 Xiao-Qi Wu Cun-Ying Xiao +3 位作者 Ali Esamdin Jing Xu Ze-Wei Wang Luo Xiao 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2024年第1期87-95,共9页
Seeing is an important index to evaluate the quality of an astronomical site.To estimate seeing at the Muztagh-Ata site with height and time quantitatively,the European Centre for Medium-Range Weather Forecasts reanal... Seeing is an important index to evaluate the quality of an astronomical site.To estimate seeing at the Muztagh-Ata site with height and time quantitatively,the European Centre for Medium-Range Weather Forecasts reanalysis database(ERA5)is used.Seeing calculated from ERA5 is compared consistently with the Differential Image Motion Monitor seeing at the height of 12 m.Results show that seeing decays exponentially with height at the Muztagh-Ata site.Seeing decays the fastest in fall in 2021 and most slowly with height in summer.The seeing condition is better in fall than in summer.The median value of seeing at 12 m is 0.89 arcsec,the maximum value is1.21 arcsec in August and the minimum is 0.66 arcsec in October.The median value of seeing at 12 m is 0.72arcsec in the nighttime and 1.08 arcsec in the daytime.Seeing is a combination of annual and about biannual variations with the same phase as temperature and wind speed indicating that seeing variation with time is influenced by temperature and wind speed.The Richardson number Ri is used to analyze the atmospheric stability and the variations of seeing are consistent with Ri between layers.These quantitative results can provide an important reference for a telescopic observation strategy. 展开更多
关键词 site testing atmospheric effects methods:data analysis telescopes EARTH
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Stability analysis of loose accumulation slopes under rainfall:case study of a high‑speed railway in Southwest China
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作者 Xin Wang Qian Su +2 位作者 Zongyu Zhang Feihu Huang Chenfang He 《Railway Engineering Science》 EI 2024年第1期95-106,共12页
The high and steep slopes along a high-speed railway in the mountainous area of Southwest China are mostly composed of loose accumulations of debris with large internal pores and poor stability,which can easily induce... The high and steep slopes along a high-speed railway in the mountainous area of Southwest China are mostly composed of loose accumulations of debris with large internal pores and poor stability,which can easily induce adverse geological disasters under rainfall conditions.To ensure the smooth construction of the high-speed railway and the subsequent safe operation,it is necessary to master the stability evolution process of the loose accumulation slope under rainfall.This article simulates rainfall using the finite element analysis software’s hydromechanical coupling module.The slope stability under various rainfall situations is calculated and analysed based on the strength reduction method.To validate the simulation results,a field monitoring system is established to study the deformation characteristics of the slope under rainfall.The results show that rainfall duration is the key factor affecting slope stability.Given a constant amount of rainfall,the stability of the slope decreases with increasing duration of rainfall.Moreover,when the amount and duration of rainfall are constant,continuous rainfall has a greater impact on slope stability than intermittent rainfall.The setting of the field retaining structures has a significant role in improving slope stability.The field monitoring data show that the slope is in the initial deformation stage and has good stability,which verifies the rationality of the numerical simulation method.The research results can provide some references for understanding the influence of rainfall on the stability of loose accumulation slopes along high-speed railways and establishing a monitoring system. 展开更多
关键词 High-speed railway Loose accumulation slope Slope stability analysis Rainfall effect Strength reduction
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Nonlinear dynamic modeling of planar moving Timoshenko beam considering non-rigid non-elastic axial effects
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作者 M.ABBASI GAVARI M.R.HOMAEINEZHAD 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第3期479-496,共18页
Due to the importance of vibration effects on the functional accuracy of mechanical systems,this research aims to develop a precise model of a nonlinearly vibrating single-link mobile flexible manipulator.The manipula... Due to the importance of vibration effects on the functional accuracy of mechanical systems,this research aims to develop a precise model of a nonlinearly vibrating single-link mobile flexible manipulator.The manipulator consists of an elastic arm,a rotary motor,and a rigid carrier,and undergoes general in-plane rigid body motion along with elastic transverse deformation.To accurately model the elastic behavior,Timoshenko’s beam theory is used to describe the flexible arm,which accounts for rotary inertia and shear deformation effects.By applying Newton’s second law,the nonlinear governing equations of motion for the manipulator are derived as a coupled system of ordinary differential equations(ODEs)and partial differential equations(PDEs).Then,the assumed mode method(AMM)is used to solve this nonlinear system of governing equations with appropriate shape functions.The assumed modes can be obtained after solving the characteristic equation of a Timoshenko beam with clamped boundary conditions at one end and an attached mass/inertia at the other.In addition,the effect of the transverse vibration of the inextensible arm on its axial behavior is investigated.Despite the axial rigidity,the effect makes the rigid body dynamics invalid for the axial behavior of the arm.Finally,numerical simulations are conducted to evaluate the performance of the developed model,and the results are compared with those obtained by the finite element approach.The comparison confirms the validity of the proposed dynamic model for the system.According to the mentioned features,this model can be reliable for investigating the system’s vibrational behavior and implementing vibration control algorithms. 展开更多
关键词 planar moving Timoshenko beam non-rigid non-elastic axial effect as-sumed mode method(AMM) nonlinear motion analysis
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Effects of postoperative treatment with chemotherapy and cellular immunotherapy on patients with colorectal cancer
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作者 Zhen-Yu Ding Ying Piao +4 位作者 Tong Jiang Juan Chen Yi-Nuo Wang Hui-Ying Yu Zhen-Dong Zheng 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第10期3202-3210,共9页
BACKGROUND The outcome of surgical treatment for colorectal cancer(CRC)remains unsatis-factory and warrants further exploration and optimization.AIM To clarify the impact of chemotherapy plus cellular immunotherapy[de... BACKGROUND The outcome of surgical treatment for colorectal cancer(CRC)remains unsatis-factory and warrants further exploration and optimization.AIM To clarify the impact of chemotherapy plus cellular immunotherapy[dendritic cell-cytokine-induced killer(DC-CIK)cell immunotherapy]on patients after CRC surgery and to explore the mediating variables.METHODS A total cohort of 121 patients who underwent CRC surgery between January 2019 and April 2022 were selected.The sample comprised a control group of 55 pa-tients who received the XELOX chemotherapy regimen and a research group of 66 patients who received XELOX+DC-CIK immunotherapy.We performed compa-rative analyses of the clinical and pathological data of the two groups,including efficacy(2-year disease-free survival[DFS]rate),the incidence of adverse events(diarrhea,myelosuppression,gastrointestinal reactions,and peripheral neuritis),serum levels of tumor markers[carcinoembryonic antigens and carbohydrate an-tigens(CA)19-9 and CA242],and T-cell subsets[cluster of differentiation(CD)3+,CD3+CD4+,CD3+CD8+,natural killer(NK),and NK T cells].We also conducted preliminary univariate and mul-tivariate analyses of the variables that affected the efficacy of the treatments.RESULTS We found a significantly higher 2-year DFS rate of treatment efficacy in the research group than in the control group,with a statistically lower incidence of adverse events.Both groups showed a reduction in serum tumor markers after treatment but there was no marked intergroup difference.After treatment,the various T-cell subgroup indicators in the control group were significantly lower than those in the research group.The indices of T-cell subsets in the research group showed no significant change from preoperative levels.Univariate analysis revealed a significant correlation between TNM staging,tumor differentiation,and the rates of nonresponse to treatment in CRC patients after surgery.Multivariate results indicated that the treatment approach significantly affected the efficacy of postoperative CRC treatment.CONCLUSION We concluded that XELOX+DC-CIK immunotherapy for postsurgical CRC patients offers reduced rates of treatment-induced adverse events,extended 2-year DFS,enhanced immunity,and increased physiological antitumor responses. 展开更多
关键词 analysis of variables affecting outcomes Cellular immunotherapy CHEMOTHERAPY Colorectal cancer Clinical effects
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Analysis and Innovative Strategies of Tax Preferential Policies to Promote the Sustainable Development of Small-Scale Individual Businesses
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作者 Tiantian Wang Xinyu Yi +1 位作者 Ziyi Zhang Jingjing Xiang 《Proceedings of Business and Economic Studies》 2024年第3期120-125,共6页
This study conducted an in-depth analysis of the current tax preferential policies for small-scale individual businesses and compared them with similar policies both domestically and internationally,aiming to reveal t... This study conducted an in-depth analysis of the current tax preferential policies for small-scale individual businesses and compared them with similar policies both domestically and internationally,aiming to reveal the advantages and disadvantages of the current system.After examining the impact of these tax preferential policies on the economic status of individual business owners and the broader social economy,this article proposes a set of innovative tax preferential strategies based on theoretical foundations.By developing these innovative strategies and clarifying their implementation paths,the aim is to promote the sustainable and healthy development of small-scale individual businesses,thereby fostering comprehensive socio-economic progress.The conclusion of this study not only summarizes policy recommendations with practical significance but also provides theoretical support for the optimization and innovation of future related systems. 展开更多
关键词 Small-scale individual operation Tax incentives Policy analysis Economic effects Innovation strategy
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Numerical Analysis of a Spiral-groove Dry-gas Seal Considering Micro-scale Effects 被引量:12
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作者 WANG Bing ZHANG Huiqiang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2011年第1期146-153,共8页
A dry-gas seal system is a non-contact seal technology that is widely used in different industrial applications.Spiral-groove dry-gas seal utilizes fluid dynamic pressure effects to realize the seal and lubrication pr... A dry-gas seal system is a non-contact seal technology that is widely used in different industrial applications.Spiral-groove dry-gas seal utilizes fluid dynamic pressure effects to realize the seal and lubrication processes,while forming a high pressure gas film between two sealing faces due to the deceleration of the gas pumped in or out.There is little research into the effects and the influence on seal performance,if the grooves and the gas film are at the micro-scale.This paper investigates the micro-scale effects on spiral-groove dry-gas seal performance in a numerical solution of a corrected Reynolds equation.The Reynolds equation is discretized by means of the finite difference method with the second order scheme and solved by the successive-over-relaxation(SOR) iterative method.The Knudsen number of the flow in the sealing gas film is changed from 0.005 to 0.120 with a variation of film depth and sealing pressure.The numerical results show that the average pressure in the gas film and the sealed gas leakage increase due to micro-scale effects.The open force is enlarged,while the gas film stiffness is significantly decreased due to micro-scale effects.The friction torque and power consumption remain constant,even in low sealing pressure and spin speed conditions.In this paper,the seal performance at different rotor face spin speeds is also described.The proposed research clarifies the micro-scale effects in a spiral-groove dry-gas seal and their influence on seal performance,which is expected to be useful for the improvement of the design of dry-gas seal systems operating in the slip flow regime. 展开更多
关键词 micro-scale effect spiral-groove dry-gas seal numerical analysis Reynolds equation
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GENETIC MODELS AND ANALYSIS METHODS FOR SEX-LINKED AND MATERNAL GENE EFFECTS 被引量:3
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作者 Zhu Jun Duan Jialong(Zhejiang Agricultural University,Hangzhou Zhejiang 310029,)(Aubui Agricultural University Hefei Anhui 230061,) 《生物数学学报》 CSCD 北大核心 1994年第4期1-9,共9页
Genetic models are proposed for analyzing sex-linked and maternal effects as well as autosomal gene effects.For the model with no genotype×environment interaction,the total genetic effect is partitioned into dire... Genetic models are proposed for analyzing sex-linked and maternal effects as well as autosomal gene effects.For the model with no genotype×environment interaction,the total genetic effect is partitioned into direct additive (A),direct dominance (D),sexlinked (L),maternal additive (Am) and maternal dominance (Dm) genetic components.For the model including genotype×environment interaction (GE),GE can also be partitioned into components of direct additive by environment interaction (AE),direct dominance by environment interaction (DE),sex-linked by environment interaction (LE),maternal additive by environment interaction (AmE ),and maternal dominance by environment interaction (DmE).Linear functions of genetic components are listed for parent,F1,and F2.A set of parents,their reciprocal F1’s and F2’s is applicable for efficient analysis.Variance and covariance components can be well mated by MINQUE(O/l) with the jackknife procedure.The t-test conducted by the jackknife procedure is applicable for detecting significance of variation.Adjusted Unbiased Prediction (AUP) method is suggested for predicting genetic effects. 展开更多
关键词 DIALLEL analysis Sex-linked and MATERNAL gene effects GENOTYPE by environment interaction Variance and COVARIANCE components Genetic prediction
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Impact of failure mode and effects analysis-based emergency management on the effectiveness of craniocerebral injury treatment 被引量:4
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作者 Xiao-Lan Shao Ya-Zhou Wang +1 位作者 Xiong-Hui Chen Wen-Juan Ding 《World Journal of Clinical Cases》 SCIE 2022年第2期554-562,共9页
BACKGROUND Craniocerebral injuries encompass brain injuries,skull fractures,cranial soft tissue injuries,and similar injuries.Recently,the incidence of craniocerebral injuries has increased dramatically due to the inc... BACKGROUND Craniocerebral injuries encompass brain injuries,skull fractures,cranial soft tissue injuries,and similar injuries.Recently,the incidence of craniocerebral injuries has increased dramatically due to the increased numbers of traffic accidents and aerial work injuries,threatening the physical and mental health of patients.AIM To investigate the impact of failure modes and effects analysis(FMEA)-based emergency management on craniocerebral injury treatment effectiveness.METHODS Eighty-four patients with craniocerebral injuries,treated at our hospital from November 2019 to March 2021,were selected and assigned,using the random number table method,to study(n=42)and control(n=42)groups.Patients in the control group received conventional management while those in the study group received FMEA theory-based emergency management,based on the control group.Pre-and post-interventions,details regarding the emergency situation;levels of inflammatory stress indicators[Interleukin-6(IL-6),C-reactive protein(CRP),and procalcitonin(PCT)];incidence of complications;prognoses;and satisfaction regarding patient care were evaluated for both groups.RESULTS For the study group,the assessed parameters[pre-hospital emergency response time(9.13±2.37 min),time to receive a consultation(2.39±0.44 min),time needed to report imaging findings(1.15±4.44 min),and test reporting time(32.19±6.23 min)]were shorter than those for the control group(12.78±4.06 min,3.58±0.71 min,33.49±5.51 min,50.41±11.45 min,respectively;P<0.05).Pre-intervention serum levels of IL-6(78.71±27.59 pg/mL),CRP(19.80±6.77 mg/L),and PCT(3.66±1.82 ng/mL)in the study group patients were not significantly different from those in the control group patients(81.31±32.11 pg/mL,21.29±8.02 mg/L,and 3.95±2.11 ng/mL respectively;P>0.05);post-intervention serum indicator levels were lower in both groups than pre-intervention levels.Further,serum levels of IL-6(17.35±5.33 pg/mL),CRP(2.27±0.56 mg/L),and PCT(0.22±0.07 ng/mL)were lower in the study group than in the control group(30.15±12.38 pg/mL,3.13±0.77 mg/L,0.38±0.12 ng/mL,respectively;P<0.05).The complication rate observed in the study group(9.52%)was lower than that in the control group(26.19%,P<0.05).The prognoses for the study group patients were better than those for the control patients(P<0.05).Patient care satisfaction was higher in the study group(95.24%)than in the control group(78.57%,P<0.05).CONCLUSION FMEA-based craniocerebral injury management effectively shortens the time spent on emergency care,reduces inflammatory stress and complication risk levels,and helps improve patient prognoses,while achieving high patient care satisfaction levels. 展开更多
关键词 Craniocerebral injury Failure modes and effects analysis theory Emergency management Treatment effect
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