A new triterpenoid saponins, raddeanoside R19 (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R119 on superoxide generation in human neutrophil were evaluated. The compound s...A new triterpenoid saponins, raddeanoside R19 (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R119 on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA) in a different concentration-dependent manner.展开更多
基金supported by National Natural Science Foundation of China(No.30500050)by Natural Science Foundation of Liaoning province of China(No.2050340)
文摘A new triterpenoid saponins, raddeanoside R19 (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R119 on superoxide generation in human neutrophil were evaluated. The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA) in a different concentration-dependent manner.