Objective:To investigate the correlation between severe stenosis or occlusion of vertebral artery(VA)and posterior circulation ischemia(PCI).Methods:A retrospective study of 408 patients with severe stenosis or occlus...Objective:To investigate the correlation between severe stenosis or occlusion of vertebral artery(VA)and posterior circulation ischemia(PCI).Methods:A retrospective study of 408 patients with severe stenosis or occlusion of the V1-V4 segment with unilateral VA was confirmed by cervical vascular ultrasound(CDU),CT angiography(CTA),and/or DSA.According to the severe stenosis or occlusion lesions,the patients were divided into V1 segment lesion group(267 cases),V2 segment disease group(40 cases),and V3-V4 segment disease group(101 cases).Depending on whether there were symptoms of posterior circulation ischemia,408 patients were divided into symptom group(195 cases)and asymptomatic group(213 cases).CDU test recorded and analyzed hemodynamic parameters:systolic peak flow rate(PSV),end diastolic flow rate(EDV),resistance index(RI),VA tube diameter(VAD).Meantime,we had assessmented the correlation between severe stenosis or occlusion of VA and PCI.Results:1.Compariing the lesion sites in affected and healthy sides of VA,there were significant differences in PSV,EDV and VAD(p=0.000).There was no significant difference in intervertebral RI when V2 was severe stenosis(p=0.762).2.When the severely stenosis or occlusion happend in V1 or V3-V4 segment,the blood flow spectrum of the affected side was significantly different from the healthy side.3.The stenosis sexual lesion of V1 and V2 had no significant correlation with PCI symptoms(dependency coefficient was 1.06,p=0.053;0.123,p=0.323);and V3-V4 stenosis sexual lesions were moderately associated with PCI symptoms(dependency coefficient=0.217,p=0.027).Conclusions:Severe stenosis or occlusion of V3-V4 segment is likely to appear PCI.CDU can effectively diagnose lesion of VA's evere stenosis or occlusion,which provides a reliable basis of timely clinical treatment and evaluation.展开更多
目的：分析椎动脉夹层动脉瘤的血管内介入治疗中支架置入和双导管技术保护小脑后下动脉（PICA）的方法及其影像和临床随访结果。方法回顾性纳入首都医科大学宣武医院神经外科2012年1月至2014年12月收治的4例累及PICA的椎动脉夹层动脉瘤...目的：分析椎动脉夹层动脉瘤的血管内介入治疗中支架置入和双导管技术保护小脑后下动脉（PICA）的方法及其影像和临床随访结果。方法回顾性纳入首都医科大学宣武医院神经外科2012年1月至2014年12月收治的4例累及PICA的椎动脉夹层动脉瘤并经血管内治疗患者的临床资料。术后6个月复查全脑DSA，临床随访12～24个月。结果4例患者中，3例采用PICA-椎动脉支架置入技术，1例采用双向双导管技术保护PICA。对4例患者介入治疗技术方面均获成功，术后即刻造影显示PICA通畅，无缺血症状；6个月造影显示动脉瘤无复发，PICA通畅，无狭窄；12～24个月随访无新发神经功能缺损症状。结论在累及PICA的椎动脉夹层动脉瘤介入治疗中，使用P I C A-椎动脉支架置入技术和双向双导管技术能够安全、有效地保护P I C A。展开更多
基金Jiangsu Province Cadre Health Research Project(No.BJ17010)Suzhou Science and Technology Development Project(No.SS201714,No.SS201859)135 major projects of the Ministry of Science and Technology:Digital Diagnosis and Treatment Demonstration Application and Clinical Solution for Stroke(No.2017YFC0114302).
文摘Objective:To investigate the correlation between severe stenosis or occlusion of vertebral artery(VA)and posterior circulation ischemia(PCI).Methods:A retrospective study of 408 patients with severe stenosis or occlusion of the V1-V4 segment with unilateral VA was confirmed by cervical vascular ultrasound(CDU),CT angiography(CTA),and/or DSA.According to the severe stenosis or occlusion lesions,the patients were divided into V1 segment lesion group(267 cases),V2 segment disease group(40 cases),and V3-V4 segment disease group(101 cases).Depending on whether there were symptoms of posterior circulation ischemia,408 patients were divided into symptom group(195 cases)and asymptomatic group(213 cases).CDU test recorded and analyzed hemodynamic parameters:systolic peak flow rate(PSV),end diastolic flow rate(EDV),resistance index(RI),VA tube diameter(VAD).Meantime,we had assessmented the correlation between severe stenosis or occlusion of VA and PCI.Results:1.Compariing the lesion sites in affected and healthy sides of VA,there were significant differences in PSV,EDV and VAD(p=0.000).There was no significant difference in intervertebral RI when V2 was severe stenosis(p=0.762).2.When the severely stenosis or occlusion happend in V1 or V3-V4 segment,the blood flow spectrum of the affected side was significantly different from the healthy side.3.The stenosis sexual lesion of V1 and V2 had no significant correlation with PCI symptoms(dependency coefficient was 1.06,p=0.053;0.123,p=0.323);and V3-V4 stenosis sexual lesions were moderately associated with PCI symptoms(dependency coefficient=0.217,p=0.027).Conclusions:Severe stenosis or occlusion of V3-V4 segment is likely to appear PCI.CDU can effectively diagnose lesion of VA's evere stenosis or occlusion,which provides a reliable basis of timely clinical treatment and evaluation.
文摘目的：分析椎动脉夹层动脉瘤的血管内介入治疗中支架置入和双导管技术保护小脑后下动脉（PICA）的方法及其影像和临床随访结果。方法回顾性纳入首都医科大学宣武医院神经外科2012年1月至2014年12月收治的4例累及PICA的椎动脉夹层动脉瘤并经血管内治疗患者的临床资料。术后6个月复查全脑DSA，临床随访12～24个月。结果4例患者中，3例采用PICA-椎动脉支架置入技术，1例采用双向双导管技术保护PICA。对4例患者介入治疗技术方面均获成功，术后即刻造影显示PICA通畅，无缺血症状；6个月造影显示动脉瘤无复发，PICA通畅，无狭窄；12～24个月随访无新发神经功能缺损症状。结论在累及PICA的椎动脉夹层动脉瘤介入治疗中，使用P I C A-椎动脉支架置入技术和双向双导管技术能够安全、有效地保护P I C A。
