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Severe bilateral anterior cingulum injury in patients with mild traumatic brain injury 被引量:4
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作者 Jae Woon Kim Han Do Lee Sung Ho Jang 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第11期1876-1878,共3页
The cingulum,the neural tract connecting the orbitofrontal cortex with the medial temporal lobe,plays an important role in cognition(Bush et al.,2000).It is also important in memory because it provides cholinergic i... The cingulum,the neural tract connecting the orbitofrontal cortex with the medial temporal lobe,plays an important role in cognition(Bush et al.,2000).It is also important in memory because it provides cholinergic innervations to the cerebral cortex after obtaining innervation from the medial septal nucleus,the vertical nucleus of the diagonal band, and the nucleus basalis of Meynert via the medial cholinergic pathway (Nieuwenhuys et al., 2008; Naidich and Duvernoy, 2009; Hong and Jang, 2010a). 展开更多
关键词 TBI Severe bilateral anterior cingulum injury in patients with mild traumatic brain injury DTT WAIS DTI
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Reorganization of injured anterior cingulums in a hemorrhagic stroke patient
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作者 Sung Ho Jang Chul Hoon Chang Han Do Lee 《Neural Regeneration Research》 SCIE CAS CSCD 2018年第8期1486-1487,共2页
In this study, we reported on a patient who showed a new neural tract between the injured anterior cingu- lums and the basal forebrain, as shown by diffusion tensor tractography (DTT).
关键词 Reorganization of injured anterior cingulums in a hemorrhagic stroke patient HDL DTT FIGURE
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Recovery of an injured anterior cingulum to the basal forebrain in a patient with brain injury: a 4-year follow-up study of cognitive function
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作者 Sung Ho Jang Hyeok Gyu Kwon 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第10期1695-1696,共2页
~[he cingulum, a long neural tract extending from the orbitof- rontal cortex to the medial temporal lobe, obtains cholinergic innervation from three cholinergic nuclei in the basal fore- brain (the nucleus basalis of... ~[he cingulum, a long neural tract extending from the orbitof- rontal cortex to the medial temporal lobe, obtains cholinergic innervation from three cholinergic nuclei in the basal fore- brain (the nucleus basalis of Meynert [Ch 4], the medial septal nucleus [Ch 1 ], and the vertical nucleus of the diagonal band [Ch 2]), and is the passage of the medial cholinergic pathway which supplies cholinergic innervation from the basal forebrain to the cerebral cortex (Folstein et al., 1975; Selden et al., 1998; Lucas-Meunier et al., 2003). Therefore, it is important for cog- nition, especially memory function (Selden et al., 1998). 展开更多
关键词 Recovery of an injured anterior cingulum to the basal forebrain in a patient with brain injury DTT MMSE Figure
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Depressive Cognitions May Affect Cingulate Neurochemistry in ADHD Patients
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作者 Evgeniy Perlov Alexandra Philipsen +4 位作者 Simon Maier Martin Buechert Bernd Hesslinger Dieter Ebert Ludger Tebartz van Elst 《Journal of Behavioral and Brain Science》 2011年第1期6-11,共6页
Objectives: The anterior cingulate is thought to be essentially involved in impulsivity and affect regulation and in the pathogenesis of depression as well as of attention deficit/hyperactivity disorder. At the same t... Objectives: The anterior cingulate is thought to be essentially involved in impulsivity and affect regulation and in the pathogenesis of depression as well as of attention deficit/hyperactivity disorder. At the same time alterations in glutamatergic neurotransmission in the frontal forebrain have been found in imaging studies in Attention Deficit Hyperactivity Disorder (ADHD) and in depressive patients. Therefore we hypothesized that glutamate/glutamine (Glx) signals in the anterior cingulate cortex (ACC) of depressed ADHD patients might differ from that in non-depressed patients. Methods: Fourteen male adult patients with ADHD were included into the study. Chemical Shift Imaging of ACC was performed. Subgroups were defined based on scores on the Beck Depression Inventory (BDI) and ratios of metabolites were compared between groups. Additionally correlation analyses of BDI scores with metabolite ratios were calculated. Results: Significantly lower Glx signals and N-acetyl-aspartate (NAA) signals were found in the left anterior cingulate cortex of depressed ADHD patients. The Glx/Cr and NAAX/Cr ratios in the left ACC correlated significantly with BDI-scores. Conclusions: To our knowledge this is the first report about a relationship between depressive symptoms and metabolite disturbances in ACC of adult patients with ADHD. Our preliminary data produce first evidence for a putative link between neurochemical alterations in the ACC and depressive symptoms. They should be controlled for in further studies. 展开更多
关键词 ADHD MR-Spectroscopy Depression anterior cingulum Glutamate
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