目的用显微外科技术切除颅底脑膜瘤,以提高全切率,降低死亡率和致残率。方法本组31例经显微外科治疗颅底脑膜瘤,采用经翼点-颧弓-颞下联合入路,并分析手术方法、结果和并发症。结果肿瘤S im pson’sⅠ、Ⅱ级全切除25例,次全切除4例,大...目的用显微外科技术切除颅底脑膜瘤,以提高全切率,降低死亡率和致残率。方法本组31例经显微外科治疗颅底脑膜瘤,采用经翼点-颧弓-颞下联合入路,并分析手术方法、结果和并发症。结果肿瘤S im pson’sⅠ、Ⅱ级全切除25例,次全切除4例,大部切除2例。术后恢复良好27例,遗留颅神经麻痹4例,无手术死亡。结论颅底脑膜瘤采用颅底外科技术,明显缩短了肿瘤显露距离,最大限度地减少了脑牵拉,同时配合显微外科技术和电磁刀,可取得良好效果。展开更多
Background Large and giant medial sphenoid wing meningiomas that are located deeply in the skull base where they are closely bounded by cavernous sinus,optic nerve,and internal carotid artery make the gross resection ...Background Large and giant medial sphenoid wing meningiomas that are located deeply in the skull base where they are closely bounded by cavernous sinus,optic nerve,and internal carotid artery make the gross resection hard to achieve.Also,this kind of meningiomas is often accompanied by a series of severe complications.Therefore,it was regarded as a formidable challenge to even the most experienced neurosurgeons.This study aimed to investigate the clinical features and management experience of patients with large and giant medial sphenoid wing meningiomas.Methods In this study,53 patients （33 female and 20 male,mean age of 47.5 years） with large and giant medial sphenoid wing meningiomas were treated surgically between April 2004 to March 2012,with their clinical features analyzed,management experience collected,and treatment results investigated retrospectively.Results In this study,gross total resection （Simpson Ⅰ and Ⅱ） was applied in 44 patients （83％）.Fifty-three patients had accepted the routine computed tomography scan and magnetic resonance imaging scan as postoperative neuroradiological evaluation.Their performance showed surgical complications of vascular lesions and helped us evaluate patients＇ conditions,respectively.Meanwhile,the drugs resisting cerebral angiospasm,such as Nimodipine,were infused in every postoperative patient through vein as routine.As a result,11 patients （21％） were found to have secondary injury of cranial nerves Ⅱ,Ⅲ,and Ⅳ,and nine patients got recovered during the long-term observing follow-up period.Temporary surgical complications of vascular lesions occurred after surgery,such as cerebral angiospasm,ischemia,and edema;24 patients （45％） appeared to have infarction and dyskinesia of limbs.Overall,visual ability was improved in 41 patients （77％）.No patient died during the process.Conclusions Microsurgical treatment may be the most effective method for the large and giant medial sphenoid wing meningiomas.The surgical strategy should focus on survival and postoperative living quality.展开更多
文摘目的用显微外科技术切除颅底脑膜瘤,以提高全切率,降低死亡率和致残率。方法本组31例经显微外科治疗颅底脑膜瘤,采用经翼点-颧弓-颞下联合入路,并分析手术方法、结果和并发症。结果肿瘤S im pson’sⅠ、Ⅱ级全切除25例,次全切除4例,大部切除2例。术后恢复良好27例,遗留颅神经麻痹4例,无手术死亡。结论颅底脑膜瘤采用颅底外科技术,明显缩短了肿瘤显露距离,最大限度地减少了脑牵拉,同时配合显微外科技术和电磁刀,可取得良好效果。
文摘Background Large and giant medial sphenoid wing meningiomas that are located deeply in the skull base where they are closely bounded by cavernous sinus,optic nerve,and internal carotid artery make the gross resection hard to achieve.Also,this kind of meningiomas is often accompanied by a series of severe complications.Therefore,it was regarded as a formidable challenge to even the most experienced neurosurgeons.This study aimed to investigate the clinical features and management experience of patients with large and giant medial sphenoid wing meningiomas.Methods In this study,53 patients （33 female and 20 male,mean age of 47.5 years） with large and giant medial sphenoid wing meningiomas were treated surgically between April 2004 to March 2012,with their clinical features analyzed,management experience collected,and treatment results investigated retrospectively.Results In this study,gross total resection （Simpson Ⅰ and Ⅱ） was applied in 44 patients （83％）.Fifty-three patients had accepted the routine computed tomography scan and magnetic resonance imaging scan as postoperative neuroradiological evaluation.Their performance showed surgical complications of vascular lesions and helped us evaluate patients＇ conditions,respectively.Meanwhile,the drugs resisting cerebral angiospasm,such as Nimodipine,were infused in every postoperative patient through vein as routine.As a result,11 patients （21％） were found to have secondary injury of cranial nerves Ⅱ,Ⅲ,and Ⅳ,and nine patients got recovered during the long-term observing follow-up period.Temporary surgical complications of vascular lesions occurred after surgery,such as cerebral angiospasm,ischemia,and edema;24 patients （45％） appeared to have infarction and dyskinesia of limbs.Overall,visual ability was improved in 41 patients （77％）.No patient died during the process.Conclusions Microsurgical treatment may be the most effective method for the large and giant medial sphenoid wing meningiomas.The surgical strategy should focus on survival and postoperative living quality.
