The protection of human rights through international cooperation has a long history.Core human rights conventions,regional human rights treaties and other human rights instruments have continuously developed the meani...The protection of human rights through international cooperation has a long history.Core human rights conventions,regional human rights treaties and other human rights instruments have continuously developed the meaning and scope of international human rights cooperation.The modern risk-laden society with a high degree of complexity and uncertainty has changed the world pattern,which calls for the building of a community with a shared future for human beings with cooperation as the starting point.Under the constant threat of the novel coronavirus,we must continue to deepen the concept of a community with a shared future for human beings,adhere to a“human rights-oriented”approach,and pay particular attention to the current supply and distribution of the COVID-19 vaccine as an important global public good.Only through solidarity and cooperation can mankind finally win the battle against this pandemic and protect human rights.展开更多
Ebola Virus Disease (EVD) outbreaks in Central and West Africa 2013-2020 were the deadliest, most intense and most widely spread. On top of this, the novel Corona Virus Disease 2019 (COVID-19) has given us all a new e...Ebola Virus Disease (EVD) outbreaks in Central and West Africa 2013-2020 were the deadliest, most intense and most widely spread. On top of this, the novel Corona Virus Disease 2019 (COVID-19) has given us all a new experience. It is imperative to draw lessons to prepare for future disease outbreaks. This was a scoping review, a method that allows the assessment of emerging evidence. The objectives of the review were to 1) describe the manifestation of the epidemics;2) elaborate on the social and economic effects;3) characterize the responses;and 4) draw lessons. The findings show that Ebola risk is permanent and even increasing. The next COVID-19 epidemic is around the corner. For Africa, the situation has been made worse by poverty and fragility of institutions. Africa’s incapacity to manufacture its own vaccines, medicines, diagnostics and protective wear has been detrimental in the management of epidemics. The need for personal and home hygiene has been emphatically brought to attention. The trust in the government and other agencies is the cornerstone in the management of emergencies. The use of armed soldiers should be discouraged, for they scare people from seeking help. It is much better to use trusted local leaders instead of strangers during pandemic emergencies. Understanding the local politics without getting involved in them is essential. It is critical to understand community and individual perception of the risk of the disease in question. Often neglected is the psycho-social aspect, which should be planned early. The science of response measures ought to be explained simply and transparently, as part of risk communication. Emergency funds should be raised, and made easy and quick to disburse. Mechanisms of sharing health technologies and knowledge need to be devised under the UN. People centeredness ought to guide the conduct of trans-border movements and all transactions during pandemics.展开更多
The global outbreak of COVID-19 has posed a great challenge to the human rights protection.On May 18,2020,the second session of the series of international seminars on"Global Pandemic Prevention and Control and H...The global outbreak of COVID-19 has posed a great challenge to the human rights protection.On May 18,2020,the second session of the series of international seminars on"Global Pandemic Prevention and Control and Human Rights Protection",organized by the Institute of Human Rights of China University of Political Science and Law under the guidance of the China Society for Human Rights Studies,was held online.The seminar was themed on the Concept of Building a Community with a Shared Future for Human Beings and International Cooperation on Pandemic Prevention and Control."Through the seminr,Chinese and foreign experts discussed in depth the values of human rights theories,the specific practices and measures taken by China and the European Union in fighting COVID-19,the protection of human rights in emergencies and the issue of human rights derogation.The seminar delivered a general consensus that prejudice should be abandoned in public health emergencies and international cooperation is continuously promoted within the framework of the United Nations to build a community with a shared future for human beings.展开更多
The COVID-19 pandemic is the largest ever infectious disease facing mankind.It challenges national governance capabilities and international patterns.On June 8,2021,the“2021 China-Europe Seminar on Human Rights”was ...The COVID-19 pandemic is the largest ever infectious disease facing mankind.It challenges national governance capabilities and international patterns.On June 8,2021,the“2021 China-Europe Seminar on Human Rights”was held in Chongqing,China.Its theme was“COVID-19 Pandemic and the Protection of the Right to Life and Health,”which focused on five topics:the impact of the COVID-19 pandemic on the protection of the rights to life and health,the response of countries against the pandemic,the protection of the right to life and health of specific groups during the pandemic response,the national responsibility for the protection of the right to life and health in the public health crisis,and global cooperation in the prevention and control of the COVID-19 pandemic.The conference reached two consensuses:First,in the face of the pandemic,countries must take responsibility for the people and protect the people’s right to life and health;second,an effective international mechanism for fighting the COVID-19 pandemic must be established as soon as possible.展开更多
Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has spread worldwide.Effective treatments against COVID-19 remain urgently in need although vaccination signific...Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has spread worldwide.Effective treatments against COVID-19 remain urgently in need although vaccination significantly reduces the incidence,hospitalization,and mortality.At present,antiviral drugs including Nirmatrelvir/Ritonavir(Paxlovid^(TM)),Remdesivir,and Molnupiravir have been authorized to treat COVID-19 and become more globally available.On the other hand,traditional Chinese medicine(TCM)has been used for the treatment of epidemic diseases for a long history.Currently,various TCM formulae against COVID-19 such as Qingfei Paidu decoction,Xuanfei Baidu granule,Huashi Baidu granule,Jinhua Qinggan granule,Lianhua Qingwen capsule,and Xuebijing injection have been widely used in clinical practice in China,which may cause potential herb-drug interactions(HDIs)in patients under treatment with antiviral drugs and affect the efficacy and safety of medicines.However,information on potential HDIs between the above anti-COVID-19 drugs and TCM formulae is lacking,and thus this work seeks to summarize and highlight potential HDIs between antiviral drugs and TCM formulae against COVID-19,and especially pharmacokinetic HDIs mediated by metabolizing enzymes and/or transporters.These well-characterized HDIs could provide useful information on clinical concomitant medicine use to maximize clinical outcomes and minimize adverse and toxic effects.展开更多
Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease stillrepresents a major concern to the relevant scientific and medical communities. The primary concern of drug ...Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease stillrepresents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists,virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviraltherapies that are broadly effective against the different species/strains of the coronaviruses in general, not only againstthe current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2“SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, includingthose of the coming ones from the next species and strains (if any). As an expert in this field, I tried, in this up-to-dateperspective “viewpoint” article, to evaluate the suitability and applicability of using the currently-availableanticoronaviral agents for the next coronavirus diseases (COVIDs) and coronaviral pandemics, highlighting the mostimportant general guidelines that should be considered in the next pandemics from the therapeutic points of view.展开更多
More than a year after its appearance and still rampant around the world,the COVID-19 pandemic has highlighted tragically how poorly the world is prepared to handle systemic risks in an increasingly hyper-connected gl...More than a year after its appearance and still rampant around the world,the COVID-19 pandemic has highlighted tragically how poorly the world is prepared to handle systemic risks in an increasingly hyper-connected global social-ecological system.The absence or clear inadequacy of global governance arrangements and mechanisms is painfully distinct and obvious.In this short article,we summarize a set of COVID-19 pandemic-related analyses and lessons that are inspired by Chinese practice.First,strong government response is one of the most important methods to control a pandemic.Second,countries should be concerned about human-to-frozen goods-to-human transmission.Third,sharing resources and experiences through cooperation is crucial to ensure an adequate health response.Based on these insights,we stress the critical importance of coordination and cooperation,and call for a global network to enhance integrated human health risk resilience.展开更多
文摘The protection of human rights through international cooperation has a long history.Core human rights conventions,regional human rights treaties and other human rights instruments have continuously developed the meaning and scope of international human rights cooperation.The modern risk-laden society with a high degree of complexity and uncertainty has changed the world pattern,which calls for the building of a community with a shared future for human beings with cooperation as the starting point.Under the constant threat of the novel coronavirus,we must continue to deepen the concept of a community with a shared future for human beings,adhere to a“human rights-oriented”approach,and pay particular attention to the current supply and distribution of the COVID-19 vaccine as an important global public good.Only through solidarity and cooperation can mankind finally win the battle against this pandemic and protect human rights.
文摘Ebola Virus Disease (EVD) outbreaks in Central and West Africa 2013-2020 were the deadliest, most intense and most widely spread. On top of this, the novel Corona Virus Disease 2019 (COVID-19) has given us all a new experience. It is imperative to draw lessons to prepare for future disease outbreaks. This was a scoping review, a method that allows the assessment of emerging evidence. The objectives of the review were to 1) describe the manifestation of the epidemics;2) elaborate on the social and economic effects;3) characterize the responses;and 4) draw lessons. The findings show that Ebola risk is permanent and even increasing. The next COVID-19 epidemic is around the corner. For Africa, the situation has been made worse by poverty and fragility of institutions. Africa’s incapacity to manufacture its own vaccines, medicines, diagnostics and protective wear has been detrimental in the management of epidemics. The need for personal and home hygiene has been emphatically brought to attention. The trust in the government and other agencies is the cornerstone in the management of emergencies. The use of armed soldiers should be discouraged, for they scare people from seeking help. It is much better to use trusted local leaders instead of strangers during pandemic emergencies. Understanding the local politics without getting involved in them is essential. It is critical to understand community and individual perception of the risk of the disease in question. Often neglected is the psycho-social aspect, which should be planned early. The science of response measures ought to be explained simply and transparently, as part of risk communication. Emergency funds should be raised, and made easy and quick to disburse. Mechanisms of sharing health technologies and knowledge need to be devised under the UN. People centeredness ought to guide the conduct of trans-border movements and all transactions during pandemics.
文摘The global outbreak of COVID-19 has posed a great challenge to the human rights protection.On May 18,2020,the second session of the series of international seminars on"Global Pandemic Prevention and Control and Human Rights Protection",organized by the Institute of Human Rights of China University of Political Science and Law under the guidance of the China Society for Human Rights Studies,was held online.The seminar was themed on the Concept of Building a Community with a Shared Future for Human Beings and International Cooperation on Pandemic Prevention and Control."Through the seminr,Chinese and foreign experts discussed in depth the values of human rights theories,the specific practices and measures taken by China and the European Union in fighting COVID-19,the protection of human rights in emergencies and the issue of human rights derogation.The seminar delivered a general consensus that prejudice should be abandoned in public health emergencies and international cooperation is continuously promoted within the framework of the United Nations to build a community with a shared future for human beings.
文摘The COVID-19 pandemic is the largest ever infectious disease facing mankind.It challenges national governance capabilities and international patterns.On June 8,2021,the“2021 China-Europe Seminar on Human Rights”was held in Chongqing,China.Its theme was“COVID-19 Pandemic and the Protection of the Right to Life and Health,”which focused on five topics:the impact of the COVID-19 pandemic on the protection of the rights to life and health,the response of countries against the pandemic,the protection of the right to life and health of specific groups during the pandemic response,the national responsibility for the protection of the right to life and health in the public health crisis,and global cooperation in the prevention and control of the COVID-19 pandemic.The conference reached two consensuses:First,in the face of the pandemic,countries must take responsibility for the people and protect the people’s right to life and health;second,an effective international mechanism for fighting the COVID-19 pandemic must be established as soon as possible.
基金supported by the National Natural Science Foundation of China(grants 82025034 and 81973392 to Huichang Bi.And grants 82274193 and 82074110 to Ling Ye)the Open Project of State Key Laboratory of Natural Medicines(grant SKLNMKF202209 to Ling Ye,China)+2 种基金the Shenzhen Science and Technology Program(No.KQTD20190929174023858 to Huichang Bi,China)Guangdong Basic and Applied Basic Research Foundation(2023A1515012859 to Shicheng Fan,China)Guangdong Medical Research Foundation(A2023109 to Shicheng Fan,China)。
文摘Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has spread worldwide.Effective treatments against COVID-19 remain urgently in need although vaccination significantly reduces the incidence,hospitalization,and mortality.At present,antiviral drugs including Nirmatrelvir/Ritonavir(Paxlovid^(TM)),Remdesivir,and Molnupiravir have been authorized to treat COVID-19 and become more globally available.On the other hand,traditional Chinese medicine(TCM)has been used for the treatment of epidemic diseases for a long history.Currently,various TCM formulae against COVID-19 such as Qingfei Paidu decoction,Xuanfei Baidu granule,Huashi Baidu granule,Jinhua Qinggan granule,Lianhua Qingwen capsule,and Xuebijing injection have been widely used in clinical practice in China,which may cause potential herb-drug interactions(HDIs)in patients under treatment with antiviral drugs and affect the efficacy and safety of medicines.However,information on potential HDIs between the above anti-COVID-19 drugs and TCM formulae is lacking,and thus this work seeks to summarize and highlight potential HDIs between antiviral drugs and TCM formulae against COVID-19,and especially pharmacokinetic HDIs mediated by metabolizing enzymes and/or transporters.These well-characterized HDIs could provide useful information on clinical concomitant medicine use to maximize clinical outcomes and minimize adverse and toxic effects.
文摘Despite the global decline in the severity of the coronavirus disease 2019 (COVID-19) cases, the disease stillrepresents a major concern to the relevant scientific and medical communities. The primary concern of drug scientists,virologists, and other concerned specialists in this respect is to find ready-to-use suitable and potent anticoronaviraltherapies that are broadly effective against the different species/strains of the coronaviruses in general, not only againstthe current and previous coronaviruses (e.g., the recently-appeared severe acute respiratory syndrome coronavirus 2“SARS-CoV-2”), i.e., effective antiviral agents for treatment and/or prophylaxis of any coronaviral infections, includingthose of the coming ones from the next species and strains (if any). As an expert in this field, I tried, in this up-to-dateperspective “viewpoint” article, to evaluate the suitability and applicability of using the currently-availableanticoronaviral agents for the next coronavirus diseases (COVIDs) and coronaviral pandemics, highlighting the mostimportant general guidelines that should be considered in the next pandemics from the therapeutic points of view.
基金The authors acknowledge support from the National Key Research and Development Program of China Project(Grant No.2016YFA0602404)the Second Tibetan Plateau Scientific Expedition and Research Program under STEP(Grant No.2019QZKK0606).
文摘More than a year after its appearance and still rampant around the world,the COVID-19 pandemic has highlighted tragically how poorly the world is prepared to handle systemic risks in an increasingly hyper-connected global social-ecological system.The absence or clear inadequacy of global governance arrangements and mechanisms is painfully distinct and obvious.In this short article,we summarize a set of COVID-19 pandemic-related analyses and lessons that are inspired by Chinese practice.First,strong government response is one of the most important methods to control a pandemic.Second,countries should be concerned about human-to-frozen goods-to-human transmission.Third,sharing resources and experiences through cooperation is crucial to ensure an adequate health response.Based on these insights,we stress the critical importance of coordination and cooperation,and call for a global network to enhance integrated human health risk resilience.