Copying,compiling,publishing,disseminating,and referencing anti-epidemic books of medical formularies were common activities during the outbreak of epidemics in the Qing dynasty.Its emergence,motivated by epidemic dis...Copying,compiling,publishing,disseminating,and referencing anti-epidemic books of medical formularies were common activities during the outbreak of epidemics in the Qing dynasty.Its emergence,motivated by epidemic disease again and again,was important component parts of epidemic prevention and control.They played a unique role as media on affairs such as treating patients suffering from infectious diseases,mobilizing peoples to make contributions to anti-epidemic activities,integrating and popularizing knowledge of epidemic prevention.Anti-epidemic books of medical formularies were important to link peoples,things,and substances related with epidemic prevention and control,and were a kind of motivation to actively deal with the infectious disease,control the epidemic,and maintain health.Compared to other common measures,anti-epidemic books of medical formularies participated in many prevention and control practices deeply,which actually built a low cost,spontaneous,dispersed and non-institutional system to respond to epidemic,and the system had characteristics of stronger conductibility,bigger coverage area,and better external benefits.展开更多
[Objectives]To explore the molecular mechanisms of Yinqiao anti-epidemic formula(YQAEF)in regulating mucosal immune system of respiratory tract.[Methods]The active components of YQAEF were obtained from the TCMSP data...[Objectives]To explore the molecular mechanisms of Yinqiao anti-epidemic formula(YQAEF)in regulating mucosal immune system of respiratory tract.[Methods]The active components of YQAEF were obtained from the TCMSP database,and RMIS targets were obtained from the GeneCards database.A"YQAEF components-RMIS targets-pathways"network was constructed by analyzing the above data to screen core targets for molecular docking verification.A mouse model of acute upper respiratory tract infection(AURI)was developed.Based on the experimental models,the key pathway target genes screened by network pharmacology were verified in vivo.[Results]The main active components of YQAEF involved in the regulation of the RMIS included quercetin,acetic acid,and raffinose.Key targets,such as angiotensin-converting enzyme(ACE),galactosidase alpha(GLA),matrix metalloproteinase 2(MMP2),Serpin Family E Member 1(SERPINE1),and myeloperoxidase(MPO)and important viral infection and endocrine resistance signaling pathways were included in the regulation of the RMIS with YQAEF.Molecular docking assays showed that the key targets had good binding activities with the components of YQAEF.Based on the results of network pharmacology,key target proteins in ACE,GLA,MMP2,SERPINE1,and MPO were selected for experimental verification.The results showed that ACE/ACE2 and MPO expressions were increased in the oral and throat mucosa of the AURI mice.Under YQAEF treatment,the expression levels of ACE/ACE2 and MPO were decreased.[Conclusions]This study revealed the mechanism of YQAEF in the regulation of RMIS,which is associated with multiple components,targets,and pathways.Further experiments confirmed that YQAEF interfered with MPO and ACE/ACE2 signaling pathways to regulate the RMIS in the oral and throat mucosa tissue of mice with AURI,and provide a new direction for exploring the potential antiviral mechanism of YQAEF.展开更多
In the process of patriotism education for primary school students,educational drama can play a very important role.However,the premise is that educational drama should be successfully integrated into the process of p...In the process of patriotism education for primary school students,educational drama can play a very important role.However,the premise is that educational drama should be successfully integrated into the process of patriotism education of primary school students,instead of simply and mechanically stuffing educational drama into patriotism education of primary school students.As far as the integration mode of educational drama is concerned,educational drama can be divided into three kinds,namely,discipline-oriented drama education,infiltration-oriented drama education and activity-oriented drama.Therefore,the integration methods are also divided into three categories,namely,setting up educational drama courses,using educational drama to infiltrate patriotic education into other disciplines and carrying out activity-oriented drama education.展开更多
Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration C...Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration Center for the practical teaching of drama and film and television disciplines.The article first introduces the background and importance of the demonstration center and then analyzes in depth the construction content and achievements of the demonstration center from four aspects:practical teaching philosophy,practical teaching system,practical teaching resources,and practical teaching effects.Finally,the article summarizes the experience and shortcomings of the demonstration center and proposes future development directions and suggestions.展开更多
In 2020 with a pandemic sweeping the world,global political and economic orders seriously disrupted and tens of millions of human lives threatened,the spread of the novel coronavirus is the world's number one chal...In 2020 with a pandemic sweeping the world,global political and economic orders seriously disrupted and tens of millions of human lives threatened,the spread of the novel coronavirus is the world's number one challenge.China has efficiently organized domestic epidemic control and vigorously promoted international cooperation in the battle against the pandemic by advancing head-of-state diplomacy.In this ongoing crisis,China has actively led the way for global public health governance,promoted the building of a community with common health for mankind,and demonstrated the actions of a responsible major country.展开更多
The COVID-19 outbreak in 2020 is a syndrome of economic,social and governance crises.It is not only a test of the medical and health system of a country or a region,but also a test of the emergency management system a...The COVID-19 outbreak in 2020 is a syndrome of economic,social and governance crises.It is not only a test of the medical and health system of a country or a region,but also a test of the emergency management system and the comprehensive governance capacity.Based on the complexity of epidemic prevention and control,no single factor can explain and respond to the"exceptional status"of epidemic prevention and control.Only by applying the"Theory of History Resultant Force",establishing systematic thinking,and comprehensively reviewing and analyzing can we comprehensively and objectively clarify its pros and cons.Having taken advantage of the party’s leadership,the nationwide system,and the Socialism with Chinese characteristics with a broad mass base and strong material support,China has achieved obvious results in a relatively short period of time in the process of epidemic prevention and control.It provides other countries or regions with Chinese experience,and Chinese wisdom for anti-epidemic efforts.展开更多
During the epidemics in the Qing dynasty,many medical professionals,nonprofessionals,and social organizations collected and sorted medical prescriptions related to infectious diseases.These people also compiled,publis...During the epidemics in the Qing dynasty,many medical professionals,nonprofessionals,and social organizations collected and sorted medical prescriptions related to infectious diseases.These people also compiled,published,disseminated,and consulted related medical formularies.The above historical event can be viewed as the construction and dissemination of medical knowledge.They edited and published medical formularies on infectious diseases with lower cost and in flexible ways by taking the initiative and giving full scope to creativity.Diverse anti-epidemic medical prescriptions from these medical formularies can be used for infectious diseases in the event of the outbreaks.However,the therapeutic effects of classical prescriptions and folk recipes cannot be regarded as the same.The wide circulation of anti-epidemic medical prescriptions and medical formularies was essentially a process of epidemic prevention resource allocation.Not only did it enable many nonprofessionals to participate in epidemic prevention and control,but it also enhanced awareness,knowledge,and capacity for epidemic prevention at the individual level.At the same time,due to the uneven quality and individual differences in the physical fitness and condition of the prescriptions and formularies,they had the capacity of causing inconveniences to the readers or patients.展开更多
This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits die traditional culture of Chinese medicine.Throug...This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits die traditional culture of Chinese medicine.Through analysis of the characteristics of the dietary regimen and the discussion of the idea of disease prevention,the application of the dietary regimen in disease prevention is sought.Under the guidance of three key factors,the application of the dietary regimen in disease prevention is mainly manifested in two aspects,h irst,the dietary regimen can be used to guide the daily reasonable diet to maintain the human body in a balance of Yin and Yang,which could prevent the occurrence of diseases.Second,on the basis of minimizing health loss,it can be used for disease treatment,adjuvant treatment,and rehabilitation.Finally,taking preventive treatment as the guiding ideology,the application of a dietary regimen as an"anti-epidemic"was briefly discussed.展开更多
With the development and popularization of the Internet, dramas from English-speaking countries, i.e., English dramas, are becoming more and more popular in China. It has become a fashion to contact and learn English ...With the development and popularization of the Internet, dramas from English-speaking countries, i.e., English dramas, are becoming more and more popular in China. It has become a fashion to contact and learn English and British & American culture through English dramas. This paper analyzes the possibility of learning English with English dramas as the medium and how to make use of English dramas to learn English scientifically and effectively;this paper also expounds the important role played by English dramas in helping students improve their English proficiency in an all-round way, especially in listening and speaking.展开更多
基金financed by the grant from the National Social Science Fund of China(No.18ZDA175)Youth Fund for Humanities and Social Sciences Research of the Ministry of Education(No.20YJC770021)。
文摘Copying,compiling,publishing,disseminating,and referencing anti-epidemic books of medical formularies were common activities during the outbreak of epidemics in the Qing dynasty.Its emergence,motivated by epidemic disease again and again,was important component parts of epidemic prevention and control.They played a unique role as media on affairs such as treating patients suffering from infectious diseases,mobilizing peoples to make contributions to anti-epidemic activities,integrating and popularizing knowledge of epidemic prevention.Anti-epidemic books of medical formularies were important to link peoples,things,and substances related with epidemic prevention and control,and were a kind of motivation to actively deal with the infectious disease,control the epidemic,and maintain health.Compared to other common measures,anti-epidemic books of medical formularies participated in many prevention and control practices deeply,which actually built a low cost,spontaneous,dispersed and non-institutional system to respond to epidemic,and the system had characteristics of stronger conductibility,bigger coverage area,and better external benefits.
基金Supported by Suzhou Science and Technology Development Plan project (SKY2022206)The Ninth Batch of Suzhou Gusu Health Key Talents Project (GSWS2022107).
文摘[Objectives]To explore the molecular mechanisms of Yinqiao anti-epidemic formula(YQAEF)in regulating mucosal immune system of respiratory tract.[Methods]The active components of YQAEF were obtained from the TCMSP database,and RMIS targets were obtained from the GeneCards database.A"YQAEF components-RMIS targets-pathways"network was constructed by analyzing the above data to screen core targets for molecular docking verification.A mouse model of acute upper respiratory tract infection(AURI)was developed.Based on the experimental models,the key pathway target genes screened by network pharmacology were verified in vivo.[Results]The main active components of YQAEF involved in the regulation of the RMIS included quercetin,acetic acid,and raffinose.Key targets,such as angiotensin-converting enzyme(ACE),galactosidase alpha(GLA),matrix metalloproteinase 2(MMP2),Serpin Family E Member 1(SERPINE1),and myeloperoxidase(MPO)and important viral infection and endocrine resistance signaling pathways were included in the regulation of the RMIS with YQAEF.Molecular docking assays showed that the key targets had good binding activities with the components of YQAEF.Based on the results of network pharmacology,key target proteins in ACE,GLA,MMP2,SERPINE1,and MPO were selected for experimental verification.The results showed that ACE/ACE2 and MPO expressions were increased in the oral and throat mucosa of the AURI mice.Under YQAEF treatment,the expression levels of ACE/ACE2 and MPO were decreased.[Conclusions]This study revealed the mechanism of YQAEF in the regulation of RMIS,which is associated with multiple components,targets,and pathways.Further experiments confirmed that YQAEF interfered with MPO and ACE/ACE2 signaling pathways to regulate the RMIS in the oral and throat mucosa tissue of mice with AURI,and provide a new direction for exploring the potential antiviral mechanism of YQAEF.
基金Supported by National Social Science Foundation (20XZX020).
文摘In the process of patriotism education for primary school students,educational drama can play a very important role.However,the premise is that educational drama should be successfully integrated into the process of patriotism education of primary school students,instead of simply and mechanically stuffing educational drama into patriotism education of primary school students.As far as the integration mode of educational drama is concerned,educational drama can be divided into three kinds,namely,discipline-oriented drama education,infiltration-oriented drama education and activity-oriented drama.Therefore,the integration methods are also divided into three categories,namely,setting up educational drama courses,using educational drama to infiltrate patriotic education into other disciplines and carrying out activity-oriented drama education.
文摘Taking the National Experimental Teaching Demonstration Center of the Central Academy of Drama as an example,this article explores the construction and development of the National Experimental Teaching Demonstration Center for the practical teaching of drama and film and television disciplines.The article first introduces the background and importance of the demonstration center and then analyzes in depth the construction content and achievements of the demonstration center from four aspects:practical teaching philosophy,practical teaching system,practical teaching resources,and practical teaching effects.Finally,the article summarizes the experience and shortcomings of the demonstration center and proposes future development directions and suggestions.
文摘In 2020 with a pandemic sweeping the world,global political and economic orders seriously disrupted and tens of millions of human lives threatened,the spread of the novel coronavirus is the world's number one challenge.China has efficiently organized domestic epidemic control and vigorously promoted international cooperation in the battle against the pandemic by advancing head-of-state diplomacy.In this ongoing crisis,China has actively led the way for global public health governance,promoted the building of a community with common health for mankind,and demonstrated the actions of a responsible major country.
文摘The COVID-19 outbreak in 2020 is a syndrome of economic,social and governance crises.It is not only a test of the medical and health system of a country or a region,but also a test of the emergency management system and the comprehensive governance capacity.Based on the complexity of epidemic prevention and control,no single factor can explain and respond to the"exceptional status"of epidemic prevention and control.Only by applying the"Theory of History Resultant Force",establishing systematic thinking,and comprehensively reviewing and analyzing can we comprehensively and objectively clarify its pros and cons.Having taken advantage of the party’s leadership,the nationwide system,and the Socialism with Chinese characteristics with a broad mass base and strong material support,China has achieved obvious results in a relatively short period of time in the process of epidemic prevention and control.It provides other countries or regions with Chinese experience,and Chinese wisdom for anti-epidemic efforts.
基金financially supported by the National Social Science Foundation of China(No.ZDA175)the Humanities and Social Science Foundation of the Ministry of Education(No.20YJC770021)。
文摘During the epidemics in the Qing dynasty,many medical professionals,nonprofessionals,and social organizations collected and sorted medical prescriptions related to infectious diseases.These people also compiled,published,disseminated,and consulted related medical formularies.The above historical event can be viewed as the construction and dissemination of medical knowledge.They edited and published medical formularies on infectious diseases with lower cost and in flexible ways by taking the initiative and giving full scope to creativity.Diverse anti-epidemic medical prescriptions from these medical formularies can be used for infectious diseases in the event of the outbreaks.However,the therapeutic effects of classical prescriptions and folk recipes cannot be regarded as the same.The wide circulation of anti-epidemic medical prescriptions and medical formularies was essentially a process of epidemic prevention resource allocation.Not only did it enable many nonprofessionals to participate in epidemic prevention and control,but it also enhanced awareness,knowledge,and capacity for epidemic prevention at the individual level.At the same time,due to the uneven quality and individual differences in the physical fitness and condition of the prescriptions and formularies,they had the capacity of causing inconveniences to the readers or patients.
文摘This article discusses the role of dietary regimen in the traditional culture of Chinese medicine according to its origin.Dietary regimen is a technique that inherits die traditional culture of Chinese medicine.Through analysis of the characteristics of the dietary regimen and the discussion of the idea of disease prevention,the application of the dietary regimen in disease prevention is sought.Under the guidance of three key factors,the application of the dietary regimen in disease prevention is mainly manifested in two aspects,h irst,the dietary regimen can be used to guide the daily reasonable diet to maintain the human body in a balance of Yin and Yang,which could prevent the occurrence of diseases.Second,on the basis of minimizing health loss,it can be used for disease treatment,adjuvant treatment,and rehabilitation.Finally,taking preventive treatment as the guiding ideology,the application of a dietary regimen as an"anti-epidemic"was briefly discussed.
文摘With the development and popularization of the Internet, dramas from English-speaking countries, i.e., English dramas, are becoming more and more popular in China. It has become a fashion to contact and learn English and British & American culture through English dramas. This paper analyzes the possibility of learning English with English dramas as the medium and how to make use of English dramas to learn English scientifically and effectively;this paper also expounds the important role played by English dramas in helping students improve their English proficiency in an all-round way, especially in listening and speaking.