A biased sampling algorithm for the restricted Boltzmann machine(RBM) is proposed, which allows generating configurations with a conserved quantity. To validate the method, a study of the short-range order in binary a...A biased sampling algorithm for the restricted Boltzmann machine(RBM) is proposed, which allows generating configurations with a conserved quantity. To validate the method, a study of the short-range order in binary alloys with positive and negative exchange interactions is carried out. The network is trained on the data collected by Monte–Carlo simulations for a simple Ising-like binary alloy model and used to calculate the Warren–Cowley short-range order parameter and other thermodynamic properties. We demonstrate that the proposed method allows us not only to correctly reproduce the order parameters for the alloy concentration at which the network was trained, but can also predict them for any other concentrations.展开更多
Collective cell migration is a coordinated movement of multi-cell systems essential for various processes throughout life.The collective motions often occur under spatial restrictions,hallmarked by the collective rota...Collective cell migration is a coordinated movement of multi-cell systems essential for various processes throughout life.The collective motions often occur under spatial restrictions,hallmarked by the collective rotation of epithelial cells confined in circular substrates.Here,we aim to explore how geometric shapes of confinement regulate this collective cell movement.We develop quantitative methods for cell velocity orientation analysis,and find that boundary cells exhibit stronger tangential ordering migration than inner cells in circular pattern.Furthermore,decreased tangential ordering movement capability of collective cells in triangular and square patterns are observed,due to the disturbance of cell motion at unsmooth corners of these patterns.On the other hand,the collective cell rotation is slightly affected by a convex defect of the circular pattern,while almost hindered with a concave defect,also resulting from different smoothness features of their boundaries.Numerical simulations employing cell Potts model well reproduce and extend experimental observations.Together,our results highlight the importance of boundary smoothness in the regulation of collective cell tangential ordering migration.展开更多
Suppose that the time series Xt satisfieswhere α0≥δ＞0,αi≥0 for i=1,2,…,q;βi,i=1,…,p, are real numbers; p and q are the order of the model. The sequence {ξt};（0,1） and is independent of {hs,s≤t} for fixed ...Suppose that the time series Xt satisfieswhere α0≥δ＞0,αi≥0 for i=1,2,…,q;βi,i=1,…,p, are real numbers; p and q are the order of the model. The sequence {ξt};（0,1） and is independent of {hs,s≤t} for fixed t. The above model is usually written as AR（p）-ARCH（q）.We consider stationary series AR（p）-ARCH（q） model and assume the stationary field is θ0. We express this statement asH1:α1≥α2…≥αq,β1≥β2≥…≥βp and we consider an order restricted testing problem, which is to testH0:α1=α2=…=αq,β1=β2=…=βpagainst H1-H0. We derive the likelihood ratio （LR） test statistic and its asymptotic distri-展开更多
In this paper, we study a stationary AR（p）-ARCH（q） model with parameter vectors α and β. We propose a method for computing the maximum likelihood estimator （MLE） of parameters under the nonnegative restriction...In this paper, we study a stationary AR（p）-ARCH（q） model with parameter vectors α and β. We propose a method for computing the maximum likelihood estimator （MLE） of parameters under the nonnegative restriction. A similar method is also proposed for the case that the parameters are restricted by a simple order： α1≥α2≥…≥αq and β1≥β2≥…≥βp. The strong consistency of the above two estimators is discussed. Furthermore, we consider the problem of testing homogeneity of parameters against the simple order restriction. We give the likelihood ratio （LR） test statistic for the testing problem and derive its asymptotic null distribution.展开更多
The parameters of probability distributions under partial order restrictions are usually estimated by maximum likelihood estimates(MLE) and formulated as a maximization problem with a multimodal objective function sub...The parameters of probability distributions under partial order restrictions are usually estimated by maximum likelihood estimates(MLE) and formulated as a maximization problem with a multimodal objective function subject to partial order restrictions. In order to obtain the global optimal estimation of parameters, this paper presents a genetic algorithm and illustrates its effectiveness by some numerical examples.展开更多
基金supported by the financing program AAAA-A16-116021010082-8。
文摘A biased sampling algorithm for the restricted Boltzmann machine(RBM) is proposed, which allows generating configurations with a conserved quantity. To validate the method, a study of the short-range order in binary alloys with positive and negative exchange interactions is carried out. The network is trained on the data collected by Monte–Carlo simulations for a simple Ising-like binary alloy model and used to calculate the Warren–Cowley short-range order parameter and other thermodynamic properties. We demonstrate that the proposed method allows us not only to correctly reproduce the order parameters for the alloy concentration at which the network was trained, but can also predict them for any other concentrations.
基金supported by the National Natural Science Foundation of China(Nos.12174208 and 32227802)National Key Research and Development Program of China(No.2022YFC3400600)+2 种基金Guangdong Major Project of Basic and Applied Basic Research(No.2020B0301030009)Fundamental Research Funds for the Central Universities(Nos.2122021337 and 2122021405)the 111 Project(No.B23045).
文摘Collective cell migration is a coordinated movement of multi-cell systems essential for various processes throughout life.The collective motions often occur under spatial restrictions,hallmarked by the collective rotation of epithelial cells confined in circular substrates.Here,we aim to explore how geometric shapes of confinement regulate this collective cell movement.We develop quantitative methods for cell velocity orientation analysis,and find that boundary cells exhibit stronger tangential ordering migration than inner cells in circular pattern.Furthermore,decreased tangential ordering movement capability of collective cells in triangular and square patterns are observed,due to the disturbance of cell motion at unsmooth corners of these patterns.On the other hand,the collective cell rotation is slightly affected by a convex defect of the circular pattern,while almost hindered with a concave defect,also resulting from different smoothness features of their boundaries.Numerical simulations employing cell Potts model well reproduce and extend experimental observations.Together,our results highlight the importance of boundary smoothness in the regulation of collective cell tangential ordering migration.
文摘Suppose that the time series Xt satisfieswhere α0≥δ＞0,αi≥0 for i=1,2,…,q;βi,i=1,…,p, are real numbers; p and q are the order of the model. The sequence {ξt};（0,1） and is independent of {hs,s≤t} for fixed t. The above model is usually written as AR（p）-ARCH（q）.We consider stationary series AR（p）-ARCH（q） model and assume the stationary field is θ0. We express this statement asH1:α1≥α2…≥αq,β1≥β2≥…≥βp and we consider an order restricted testing problem, which is to testH0:α1=α2=…=αq,β1=β2=…=βpagainst H1-H0. We derive the likelihood ratio （LR） test statistic and its asymptotic distri-
文摘In this paper, we study a stationary AR（p）-ARCH（q） model with parameter vectors α and β. We propose a method for computing the maximum likelihood estimator （MLE） of parameters under the nonnegative restriction. A similar method is also proposed for the case that the parameters are restricted by a simple order： α1≥α2≥…≥αq and β1≥β2≥…≥βp. The strong consistency of the above two estimators is discussed. Furthermore, we consider the problem of testing homogeneity of parameters against the simple order restriction. We give the likelihood ratio （LR） test statistic for the testing problem and derive its asymptotic null distribution.
文摘The parameters of probability distributions under partial order restrictions are usually estimated by maximum likelihood estimates(MLE) and formulated as a maximization problem with a multimodal objective function subject to partial order restrictions. In order to obtain the global optimal estimation of parameters, this paper presents a genetic algorithm and illustrates its effectiveness by some numerical examples.
