[Objectives]To establish a new management model for rational use of perioperative antibacterial drugs in surgical departments.[Methods]Based on evidence-based medicine,the department s drug pathway was formulated,and ...[Objectives]To establish a new management model for rational use of perioperative antibacterial drugs in surgical departments.[Methods]Based on evidence-based medicine,the department s drug pathway was formulated,and the new mode of rational drug use control was established by using fine pharmaceutical technology intervention,and the intervention effect was evaluated by the intensity of antibacterial drug use,per capita drug costs and the proportion of drugs.[Results]After adopting drug pathway in departments,the intensity of antibacterial drug use,per capita drug costs and the proportion of drugs decreased significantly,and the effect of rational drug use control was remarkable.[Conclusions]The drug pathway provides a new management and control mode for the rational use of perioperative antibacterial drugs in surgical departments of hospitals.Thus,it is worthy of popularization and application.展开更多
目的采用熵权优劣解距离法(technique for order preference by similarity to ideal solution,TOPSIS)评估临床药师干预前后剖宫产围手术期预防应用抗菌药物的合理性。方法依据《抗菌药物临床应用指导原则》(2015年版),参照药物说明书...目的采用熵权优劣解距离法(technique for order preference by similarity to ideal solution,TOPSIS)评估临床药师干预前后剖宫产围手术期预防应用抗菌药物的合理性。方法依据《抗菌药物临床应用指导原则》(2015年版),参照药物说明书及相关指南,建立基于熵权TOPSIS的剖宫产围手术期预防性应用抗菌药物评价细则,对新乡医学院第三附属医院2021年第一季度和2022年第一季度出院的剖宫产手术病例进行用药合理性评价。结果与最优方案接近程度(Ci)不小于0.6的病例数由干预前的4例(3.48%)上升至38例(38%),差异有统计学意义(P<0.05)。干预前后十个评价指标中熵权值最大的均为给药时机,权重分别为0.6843和0.7517。结论基于熵权TOPSIS法对剖宫产围手术期预防应用抗菌药物合理性可以综合多个指标进行量化评估,也可对临床药师干预效果进行评价,可为合理用药提供指导。展开更多
基金Supported by Science and Technology Innovation Plan for Medical Workers in Shandong Province(SDYWZGKCJH2023095)Clinical Pharmacy Research Project of Shandong Provincial Medical Association(YXH2022ZX010)+1 种基金Traditional Chinese Medicine Science and Technology Development Project of Shandong Province(2019-0400&2021Q097)Traditional Chinese Medicine Research Program of Qingdao City(2020-zyy031)Medical Research Guidance Plan of Qingdao City(2020-WJZD087).
文摘[Objectives]To establish a new management model for rational use of perioperative antibacterial drugs in surgical departments.[Methods]Based on evidence-based medicine,the department s drug pathway was formulated,and the new mode of rational drug use control was established by using fine pharmaceutical technology intervention,and the intervention effect was evaluated by the intensity of antibacterial drug use,per capita drug costs and the proportion of drugs.[Results]After adopting drug pathway in departments,the intensity of antibacterial drug use,per capita drug costs and the proportion of drugs decreased significantly,and the effect of rational drug use control was remarkable.[Conclusions]The drug pathway provides a new management and control mode for the rational use of perioperative antibacterial drugs in surgical departments of hospitals.Thus,it is worthy of popularization and application.
文摘目的采用熵权优劣解距离法(technique for order preference by similarity to ideal solution,TOPSIS)评估临床药师干预前后剖宫产围手术期预防应用抗菌药物的合理性。方法依据《抗菌药物临床应用指导原则》(2015年版),参照药物说明书及相关指南,建立基于熵权TOPSIS的剖宫产围手术期预防性应用抗菌药物评价细则,对新乡医学院第三附属医院2021年第一季度和2022年第一季度出院的剖宫产手术病例进行用药合理性评价。结果与最优方案接近程度(Ci)不小于0.6的病例数由干预前的4例(3.48%)上升至38例(38%),差异有统计学意义(P<0.05)。干预前后十个评价指标中熵权值最大的均为给药时机,权重分别为0.6843和0.7517。结论基于熵权TOPSIS法对剖宫产围手术期预防应用抗菌药物合理性可以综合多个指标进行量化评估,也可对临床药师干预效果进行评价,可为合理用药提供指导。
