In vitro maturation of mammalian oocytes is a key step during in vitro production of mammalian embryos.Studies have shown that the level of oocyte maturation is positively correlated with embryo cleavage rate and blas...In vitro maturation of mammalian oocytes is a key step during in vitro production of mammalian embryos.Studies have shown that the level of oocyte maturation is positively correlated with embryo cleavage rate and blastocyst rate.However,reactive oxygen species(ROS)in vitro is one of the main influencing factors of oocyte maturation.The results indicate that the addition of antioxidants can effectively improve in vitro oocyte maturation level and reduce the adverse effects of reactive oxygen species,which contribute to oocyte development.This paper summarizes research progresses on the effects of different antioxidants on in vitro development of mammalian oocytes,which is conducive to further analysis of the mechanism of action.展开更多
基金Supported by National Natural Science Foundation of China(413010028)
文摘In vitro maturation of mammalian oocytes is a key step during in vitro production of mammalian embryos.Studies have shown that the level of oocyte maturation is positively correlated with embryo cleavage rate and blastocyst rate.However,reactive oxygen species(ROS)in vitro is one of the main influencing factors of oocyte maturation.The results indicate that the addition of antioxidants can effectively improve in vitro oocyte maturation level and reduce the adverse effects of reactive oxygen species,which contribute to oocyte development.This paper summarizes research progresses on the effects of different antioxidants on in vitro development of mammalian oocytes,which is conducive to further analysis of the mechanism of action.
