Brainstem auditory evoked potentials in patients with delayed encephalopathy after acute carbon monoxide poisoning

Objective:To evaluate the changes of brainstem auditory evoked potential (BAEP) in patients with delayed encephalopathy after acute carbon monoxide poisoning. Methods: BAEPs were performed in 32 controls and 40 patients. Wave Ⅰ , Ⅱ , Ⅲ ,Ⅳ, Ⅴ latencies and Ⅰ-Ⅲ , Ⅲ-Ⅴ , Ⅰ-Ⅴ interpeak latencies were measured, respectively. Results: Abnormalities of BAEPs in 13 patients (13/40, 32 ％). Among the13 abnormal BAEPs, 3 displayed prolongation of latency to waves in one side, no potential in another side; 5 displayed a similar abnormality which was bilateral prolongation of latency to waves ;and another 5 displayed unilateral latency delay. Compared wave Ⅰ , Ⅱ , Ⅲ , Ⅳ, Ⅴ latencies and Ⅰ-Ⅲ , Ⅲ-Ⅴ , Ⅰ-Ⅴ interpeak latencies in the patients and the controls, there were no significant differences (P＞0.05). Conclusion: BAEPs can be used for evaluating the diagnostic and prognostic values in the cases of delayed encephalopathy after acute carbon monoxide poisoning.

Characteristics of brainstem auditory evoked potentials of students studying folk dance

BACKGROUND： Previous experiments have demonstrated that brainstem auditory evoked potential is affected by exercise, exercise duration, and frequency. OBJECTIVE： Comparing the brainstem auditory evoked potential of students studying folk dance to students studying other subjects. DESIGN： Observational contrast study. SETTING： Physical Education College, Shandong Normal University PARTICIPANTS： Fifty-five female students were enrolled at Shandong Normal University between September and December in 2005, including 21 students that studied folk dance and 34 students that studied other subjects. The age of the folk dance students averaged （19 ± 1） years and dance training length was （6.0 ± 1.5） years. The students that studied other subjects had never taken part in dance training or other physical training, and their age averaged （22 ± 1） years, body height averaged （162 ± 5） cm, body mass averaged （51 ± 6） kg. All subjects had no prior ear disease or history of other neurological disorders. All students provided informed consent for the experimental project. METHODS： The neural electricity tester, NDI-200 （Shanghai Poseidon Medical Electronic Instrument Factory） was used to examine and record Brainstem Auditory Evoked Potential values of the subjects during silence, as well as to transversally analyze the Brainstem Auditory Evoked Potential values. The electrode positions were cleaned and degreased with soapy water, followed by ethanol. The selected bipolar electrodes were situated on the head： recording electrodes were placed at the Baihui acupoint, and the reference electrode was placed at the mastoid of the measured ear, with grounding electrodes in the center of the forehead. Brainstem Auditory Evoked Potential values were elicited by monaural stimulation of a ＂click＂ though an earphone; the other ear was sheltered by the white noise. The click intensity was 102 db, the stimulation frequency was 30 Hz, the bandpass filters were 1 000-3 000 Hz, the sensitivity was 5 ta V, and a total of 2 000 sweeps were averaged. Waveform identification and analysis： various components of the Brainstem Auditory Evoked Potential values were identified, and the peak latencies and peak-peak values were analyzed. MAIN OUTCOME MEASURES： Latency of Ⅰ , Ⅱ, Ⅲ, Ⅳ, Ⅴ and Peak-Peak Value of Ⅰ, Ⅲ, Ⅴwere measured. RESULTS： Fifty-five subjects were enrolled in the final analysis, without any loss. Compared to the students who studied other subjects ① Ⅰ -Ⅴ peak latencies （PL）： Ⅳ PL of the right ear of the folk dance students was obviously longer （P 〈 0.05）; ② Ⅰ, Ⅲ, V peak-peak values：Ⅰ peak-peak values of the right ear were obviously higher （P 〈 0.05）. CONCUSION： ① PL of the right ear of the folk dance students was obviously longer, which indicates that dancing results in a stronger sensibility to auditory stimuli. ②. Peak-peak values were obviously higher, which indicates that long-term exercise enhances the music senses and synchrony of auditory nerve impulses.

Characteristics of brainstem auditory evoked potential of neonates with mild or moderate hyperbilirubinemia

BACKGROUND： Brainstem auditory evoked potential （BAEP） has been widely used to evaluate the functional integrity and development of injured auditory system and brain, especially to objectively evaluate the function of auditory system and brain stem of very young babies, such as neonates and sick babies. OBJECTIVE： To observe the changes of BAEP of neonates with hyperbilirubinemia, and to investigate the relationship of bilirubin concentration and BAEP. DESIGN： An observation experiment. SETTING： Department of Pediatrics, the 309 Clinical Division, General Hospital of Chinese PLA. PARTICIPANTS： Fifty-eight neonates with mild or moderate hyperbilirubinemia exhibiting jaundice within 24 hours after born, who received the treatment in the Department of Pediatrics, the 309 Clinical Division, General Hospital of Chinese PLA between January 2004 and May 2007, were recruited in this study. The involved neonates, 31 boys and 27 girls, had gestational age of 37 to 46 weeks. They had no history of birth asphyxia, and were scored 8 to 10 points when born. Written informed consents of examination and treatment were obtained from the guardians of the neonates. This study was approved by the Hospital Ethics Committee. According to serum total bilirubin value, the neonates were assigned into 3 groups： low-concentration bilirubin group （n =16）, moderate-concentration bilirubin group （n =27） and high-concentration bilirubin group （n =15）. According to mean daily bilirubin increase, the subjects were sub-assigned into bilirubin rapid increase group （n =39） and bilirubin slow increase group （n = 19）. METHODS： After admission, all the neonates received drug treatment. Meanwhile, their 116 ears were examined with a myoelectricity evoked potential equipment （KEYPOINT） in latency, wave duration, amplitude and wave shape differentiation of each wave of BAEP. BAEP abnormal type was observed and abnormal rate of BAEP was calculated. MAIN OUTCOME MEASURES： ①Abnormal rate and abnormal type of BAEP. ② Latency of waves Ⅰ , Ⅲ and Ⅴ, and wave duration of waves Ⅰ to Ⅲ,Ⅲ to Ⅴ, and Ⅰ to Ⅴ. RESULTS： Fifty-eight neonates with mild or moderate hyperbilirubinemia were involved in the final analysis. ①Abnormal type and abnormal rate of BAEP of neonates with hyperbilirubinemia： Among the 116 ears, unilateral or bilateral waves Ⅰ, Ⅲ,Ⅴ still existed. The latency of waves Ⅰ, Ⅲ and Ⅴ was ＋2.5 s longer than the normal level in 8, 4 and 15 ears, respectively. The wave duration of waves Ⅰ to Ⅲ and waves Ⅲ to Ⅴ was ＋2.5 s longer than the normal level in 6 and 14 ears, respectively. The wave duration of waves Ⅲ to Ⅴ was longer than that of ipsilateral waves Ⅰ to Ⅲ in 24 ears. The latency difference of wave Ⅴ between two ears was larger than 0.4 ms in 31 neonates with hyperbilirubinemia; The amplitude of wave Ⅴ to that of ipsilateral wave 1 was lower than 0.5 in 29 neonates. Totally 52 ears were abnormal, and the abnormal rate was 44.8%. One to two months later, 98% abnormal neonates with hyperbilirubinemia recovered. The abnormal rate in the low-, moderate-, and high-concentration bilirubin groups was 37.5%, 44.4% and 53.3%, respectively. ② Comparison of latency and wave duration of each wave of BAEP： Latency of waves Ⅰ, Ⅲ and Ⅴ, and wave duration of waves Ⅰ to III and Ⅲ to Ⅴ were gradually prolonged in low-, moderate-, and high-concentration bilirubin groups, but significant difference did not exist between two groups （P 〉 0.05）. ③ There were no significant differences in latency of waves Ⅰ, Ⅲand Ⅴ, and wave duration of waves Ⅰ to Ⅲ, Ⅲto Ⅴ and Ⅰ to Ⅴ between bilirubin rapid increase group and bilirubin slow increase group （P 〉 0.05）. CONCLUSION： Auditory acuity and brainstem of neonates with mild or moderate hyperbilirubinemia are damaged to some extent. High-concentration bilirubin causes BAEP abnormality easily. Bilirubin increase and its concentration change are not consistent with nervous lesion degree.

Electroencephalogram and brainstem auditory evoked potential in 539 patients with central coordination disorder

BACKGROUND： Electroencephalogram （EEG） and brainstem auditory evoked potential （BAEP） are objective non-invasive means of measuring brain electrophysiology. OBJECTIVE： To analyze the value of EEG and BAEP in early diagnosis, treatment and prognostic evaluation of central coordination disorder. DESIGN, TIME AND SETTING： This case analysis study was performed at the Rehabilitation Center of Hunan Children＇s Hospital from January 2002 to January 2006. PARTICIPANTS： A total of 593 patients with severe central coordination disorder, comprising 455 boys and 138 girls, aged 1-6 months were enrolled for this study. METHODS： EEG was monitored using electroencephalography. BAEP was recorded using a Keypoint electromyogram device. Intelligence was tested by professionals using the Gesell scale. MAIN OUTCOME MEASURES： （1） The rate of abnormal EEG and BAEP, （2） correlation of abnormalities of EEG and BAEP with associated injuries, （3） correlation of abnormalities of EEG and BAEP with high risk factors. RESULTS： The rate of abnormal EEG was 68.6% （407/593 patients）, and was increased in patients who also had mental retardation （P 〈 0.05）. The rate of abnormal BAEP was 21.4% （127/593 patients）. These 127 patients included 67 patients （52.8%） with peripheral auditory damage and 60 patients （47.2%） with central and mixed auditory damage. The rate of abnormal BAEP was significantly increased in patients who also had mental retardation （P 〈 0.01 ）. Logistic regression analysis showed that asphyxia （P 〈 0.05）, jaundice, preterm delivery, low birth weight and the umbilical cord around the neck were closely correlated with abnormal EEG in patients with central coordination disorder, lntracranial hemorrhage, jaundice （P 〈 0.05）, low birth weight and intrauterine infection （P 〈 0.05） were closely correlated with abnormal BAEP in patients with central coordination disorder. CONCLUSION： Central coordination disorder is often associated with abnormal EEG and BAEP. The rate of EEG or BAEP abnormality is positively associated with the size of the brain injury. Asphyxia is a high risk factor for abnormal EEG in central coordination disorder. Jaundice and intrauterine infection are high risk factors for abnormal BAEP in central coordination disorder.

The effect of lead on brainstem auditory evoked potentials in children

To determine whether lead affects brainstem auditory evoked potentials (BAEPs) in low-to-moderate lead exposed children Methods BAEPs were recorded from 114 asymptomatic children aged 1-6 years Average values were calculated for peak latency (PL) and amplitude (Amp) Whole blood lead (PbB) levels were assessed by graphite furnace atomic absorption spectroscopy Based on their PbB levels, subjects were divided into low lead (PbB<100 μg/L) and high lead subgroups (PbB ≥100 μg/L) Results The PbB levels of the 114 subjects ranged from 32 0 to 380 0 μg/L in a positively skewed distribution The median of PbB levels was 90 0 μg/L while the arithmetic average was 88 0 μg/L Of the subjects, 43 0% (49/114) had levels equal to or greater than 100 μg/L Bilateral PLs Ⅰ, Ⅴ, and Ⅲ of the left ear in the high lead subgroup were significantly longer than those in the low lead subgroup (P<0 05) A positive correlation was found between PbB levels and bilateral PLs Ⅰ, Ⅴ and Ⅲ of the left ear (P<0 05), after controlling for age and gender as confounding factors A significant and positive correlation between PbB levels and PL Ⅰ of the left ear, even when PbB levels were lower than 100 μg/L, in the low subgroup (r=0 295, P=0 019) was also found Conclusions Lead poisoning in children younger than 6 years old is a very serious problem to which close attention should be paid The indications that lead prolongs partial PLs may imply that lead, even at PbB levels lower than 100 μg/L, impairs both the peripheral and the central portions of the auditory system BAEPs may be a sensitive detector of subclinical lead exposure effects on the nervous system in children

Brainstem auditory evoked potential combined with high resolution cranial base CT can optimize the diagnosis of auditory nerve injury

Purpose:Auditory nerve injury is one of the most common nerve injury complications of skull base fractures.However,there is currently a lack of auxiliary examination methods for its direct diagnosis.The purpose of this study was to find a more efficient and accurate means of diagnosis for auditory nerve injury.Methods:Through retrospectively analyzing the results of brainstem auditory evoked potential(BAEP)and high-resolution CT(HRCT)in 37 patients with hearing impairment following trauma from January 1,2018 to July 31,2020,the role of the two inspection methods in the diagnosis of auditory nerve injury was studied.Inclusion criteria were patient had a clear history of trauma and unilateral hearing impairment after trauma;while exclusion criteria were:(1)severe patient with a Glasgow coma scale score<5 because these patients were classified as severe head injury and admitted to the intensive care unit,(2)patient in the subacute stage admitted 72 h after trauma,and(3)patient with prior hearing impairment before trauma.According to Goodman's classification of hearing impairment,the patients were divided into low/medium/severe injury groups.In addition,patients were divided into HRCT-positive and negative groups for further investigation with their BAEP results.The positive rates of BEAP for each group were observed,and the results were analyzed by Chi-square test(p<0.05,regarded as statistical difference).Results:A total of 37 patients were included,including 21 males and 16 females.All of them were hospitalized patients with GCS score of 6-15 at the time of admission.The BAEP positive rate in the medium and severe injury group was 100%,which was significantly higher than that in the low injury group(27.27%)(p<0.01).The rate of BEAP positivity was significantly higher in the HRCT-positive group(20/30,66.7%)than in the HRCT-negative group(1/7,14.3%)(p<0.05).Twenty patients(54.05%)were both positive for BEAP and HRCT test,and considered to have auditory nerve damage.Six patients(16.22%)were both negative for BEAP and HRCT test,and 10 patients(27.03%)were BAEP-negative but HRCT-positive:all the 16 patients were considered as non-neurological injury.The rest 1 case(2.70%)was BAEP-positive but HRCT-negative,which we speculate may have auditory nerve concussion.Conclusion:By way of BAEP combining with skull base HRCT,we may improve the accuracy of the diagnosis of auditory nerve injury.Such a diagnostic strategy may be beneficial to guiding treatment plans and evaluating prognosis.

RELATIONS OF INTRACRANIAL PRESSURE, CREATINE KINASE AND BRAINSTEM AUDITORY EVOKED POTENTIAL IN PATIENTS WITH TRAUMATIC BRAIN EDEMA

We studied the relations of intracranial pressure (ICP),creatine kinase (CK) and bralnstem auditory evoked potential (BAEP) in 44 patients with traumatic brain edema who were admitted to our hospital from June 1990 to February 1991. There were 30 males and 14 females, with age range from 9 to 67 years. The results showed that the abnormal BAEP could reflect the severity of cerebral edema in acute head injury and was related to ICP and serum CK levels. When ICP>30 mmHg (4kPa), the abnormality of BAEP was more obvious than that of the control group (P<0.05); the serum CK levels were also elevated markedly. In patients with ICP over and below 4kPa, the rate of abnormal BAEP was 38.46% and 77.78% respectively (P<0.05). The serum CK level in the normal group or in the group with moderate abnormality of BAEP was significantly different from that in the group with severe abnormality or lack of BAEP (274.8± 98.24 U/L vs 705.3± 364.27 U/L; P<0.001). After treatment, the ICP returned to normal, and the BAEP norm

Dysfunction of the peripheral and central auditory pathway in patients with type 1 diabetes mellitus

Although auditory alterations are not a typical symptom of diabetes mellitus (DM), they can occur in patients with type 1 DM. The findings of previous studies are controversial, because the frequency and degree of hearing loss varies, and quite often alterations are still subclinical. The typical test used to detect and manage hearing loss is the audiogram, but this test alone is only capable of detecting alterations due to injury of the inner hair cells and/or alterations in the central auditory pathway. However, auditory alterations resulting from a dysfunction that is still subclinical are only able to be detected through electrophysiological auditory tests, such as the otoacoustic emissions (OAE) and the auditory brainstem response (ABR) tests. Thus, the purpose of this paper is to review the studies that utilize the OAE and ABR tests, and to verify if the dysfunction is cochlear and/or neural in patients with type 1 DM. The findings of this review demonstrate that patients with type 1 DM can have auditory alterations stemming from a central cochlear origin. Following this finding, early diagnosis is very important in order to implement preventative treatments and initiate therapy.

Impacts of acupuncture on brainstem evoked potentials in patients with primary depression

Objective To observe the impacts of acupuncture on brainstem evoked potentials in the patients with primary depression. Methods Forty cases of primary depression were treated by acupuncture at Baihui （百会 GV 20）, Yinatng （印堂 GV 29）, DazhuT （大椎 GV 14）, bilateral Shenmen （神门 HT 7）, bilateral Taichong （太冲 LR 3）, bilateral Neiguan （内关 PC 6） and SanyTnjiao （三阴交 SP 6）. The needles were retained for 30 min. Acupuncture treatment was given once every two days, three treatments a week. The brainstem auditory evoked potential （BAEP） and visual evoked potential （VEP） were observed in 6 weeks of treatment. The change in Hamilton depression scale （HAMD） score was observed before and after treatment in the depression group. Results After treatment, VEP wave latency was shortened significantly in patients of depression （P〈0.05）, BAEPIII wave latency was shortened significantly （P〈0.05）. The score of HAMD was decreased apparently in the depression group （P〈0.05）. Conclusions The stressability of visual and auditory stimuli in the central nervous system was decreased in the patients of depression. Acupuncture shortens remarkably the brainstem evoked potentials latency in the patients of depression and achieves the effective results in the treatment of primary depression.

Combined monitoring of evoked potentials during microsurgery for lesions adjacent to the brainstem and intracranial aneurysms

Background Neurophysiologic monitoring during surgery is to prevent permanent neurological injury resulting from surgical manipulation. To improve the accuracy and sensitivity of intraoperative neuromonitoring, combined monitoring of transcranial electrical stimulation motor evoked potentials （TES-MEPs）, somatosensory evoked potentials （SSEPs） and brainstem auditory evoked potentials （BAEPs） was attempted in microsurgery for lesions adjacent to the brainstem and intracranial aneurysms. Methods Monitoring of combined TES-MEPs with SSEPs was attempted in 68 consecutive patients with lesions adjacent to the brainstem as well as intracranial aneurysms. Among them, 31 patients （31 operations, 28 of posterior cranial fossa tumors, 3 of posterior circulation aneurysms） were also subjected to monitoring of BAEPs. The correlation of monitoring results and clinical outcome was studied prospectively. Results Combined monitoring of evoked potentials （EPs） was done in 64 （94.1%） of the 68 patients. MEPs monitoring was impossible for 4 patients （5.9%）. No complication was observed during the combined monitoring in all the patients. In 45 （66.2%） of the 68 patients, EPs were stable, and they were neurologically intact. Motor dysfunction was detected by MEPs in 8 patients, SSEPs in 5, and BAEPs in 4, respectively. Conclusions A close relationship exists between postoperative motor function and the results of TES-MEPs monitoring TES-MEPs are superior to SSEPs and BAEPs in detecting motor dysfunction, but combined EPs serve as a safe, effective and invasive method for intraoperative monitoring of the function of the motor nervous system. Monitoring of combined EPs during microsurgery for lesions adjacent to the brainstem and intracranial aneurysms may detect potentially hazardous maneuvers and improve the safety of subsequent procedures.

Otoacoustic Emissions and Evoked Potentials in Infants after Breast-Feeding Jaundice——Hearing Dysfunction in Breast-Feeding Jaundice

We study hearing in a group of infants with Breast-feeding jaundice (BFJ) by means of Transient-evoked otoacoustic emissions (T-EOE) and Brainstem auditory evoked potentials (BAEP) searching for relationship between bilirubin serum levels and auditory dysfunction. Eleven infants born at-term with BFJ were selected for the study. We studied also 11 control age- and gender matched healthy at-term infants without signs of jaundice. T-EOAE studies were performed between 5-7 days after birth, and 3 months later. BAEP studies were performed once. BFJ group infants exhibited lower amplitudes in T-EOE than infants in the control group. These differences disappear at the 3-month evaluation. In BAEP, we observed a significant latency delay of waves I and V in Breast-feeding jaundice group infants. All infants in both groups demonstrated reproducible wave V response at 30 decibels. No significant correlation values were observed between bilirubin serum levels and T-EOE and BAEP variables. Our data suggest that BFJ can result in transient peripheral and central auditory dysfunction. Dysfunction is reversible after treatment of infants with BFJ.

年龄相关性听力损失患者客观反应阈与纯音听阈相关性分析

目的分析不同听力损失程度年龄相关性听力损失(ARHL)患者听性脑干反应(cABR)、40 Hz听觉相关电位(40 Hz-AERP)、多频稳态听觉诱发电位(ASSR)反应阈与纯音听阈(PTA)的相关性。方法选取2023年1月至12月期间福建医科大学附属第一医院耳鼻咽喉头颈外科收治的122例(男性67例,女性55例)年龄相关性听力损失患者,运用PTA、cABR、40 Hz-AERP、ASSR为一组测试组合,对122例ARHL患者进行检测,分析ABR、40Hz-AERP(0.5kHz、1kHz)、ASSR(0.5kHz、1kHz、2kHz、4kHz)客观反应阈与PTA0.5kHz、1kHz、2kHz、4 kHz的主观听阈的差值及相关性。结果除重度组外,cABR反应阈与PTA 2 kHz、4 kHz及2 kHz+4 kHz均值相关性均有统计学意义(P<0.05);40 Hz-AERP反应阈与PTA阈值差值在0.5 kHz处略小于1 kHz,其中最小差值为8.08±4.88 dB,最大为15.13±9.76 dB;除极重度组1 kHz外,40 Hz-AERP反应阈分别与PTA阈值相关性均有统计学意义(P<0.05);0.5 kHz处的ASSR与PTA反应阈的差值明显高于其他频率,尤其是在重度听力损失组,0.5kHz处的ASSR反应阈与PTA阈值的差值最大,为16.13±12.32dBHL;除极重度组2kHz外,不同听力损失组中ASSR反应阈与PTA听阈值之间的差异具有显著统计学意义(P<0.05),并且存在明显的相关性。结论40 Hz AERP和ASSR的联合应用有助于判断PTA 0.5 kHz和1 kHz频率的阈值;cABR和ASSR的联合应用有助于判断PTA 2.0 kHz和4.0 kHz频率的阈值。通过40Hz-AERP、cABR、ASSR以及PTA等联合应用有助于提高ARHL患者听力损失程度评估的准确性和可靠性。

皮层听觉诱发电位在听力障碍法医学鉴定中的应用

目的 分析残余噪声水平(residual noise level,RNL)对听性脑干反应(auditory brainstem response,ABR)有效识别率的影响,ABR与40 Hz听觉事件相关电位(40Hz audiotory event related potential,40HzAERP)和皮层听觉诱发电位(cortical auditory evoked potential,CAEP)反应阈相关性,探讨CAEP应用于听力障碍法医学鉴定的意义。方法 对26例52耳听力障碍法医学鉴定人群进行听觉神经电生理测试,测量并分析左右两耳所有ABR曲线中的RNL最大值,分析CAEP结果,分析ABR与40HzAERP、CAEP反应阈相关性。结果 ABR曲线有效识别率92.31%,CAEP均可有效识别为引出或未引出反应。1、2 kHz短纯音刺激CAEP反应幅值均高于ABR;ABR与1、2 kHz短纯音刺激的40HzAERP反应阈无相关,差异无统计学意义(P>0.05);ABR与1、2 kHz短纯音刺激的CAEP反应阈无相关,差异无统计学意义(P>0.05);1、2 kHz短纯音刺激40HzAERP与CAEP反应阈无相关,差异无统计学意义(P>0.05)。结论 CAEP不易受到RNL异常增高因素的影响,可获得较为可靠的测试结果,且具有频率特异性,反应阈值与其他客观听力测试结果之间具有稳定的相关性,可作为因RNL异常增高导致ABR无法测试人群进行听力障碍法医学鉴定的方法之一。

良性阵发性位置性眩晕患者的耳石器及半规管功能分析

目的探讨良性阵发性位置性眩晕(BPPV)对耳石器及半规管功能的影响及其可能的发病因素。方法选择2022年12月-2023年6月本院收治的单管良性阵发性位置性眩晕患者作为研究对象,分别行视频头脉冲试验(vHIT)、前庭肌源诱发电位(VEMP)、听性脑干反应(ABR),分析其检测结果。结果后半规管BPPV患者与水平半规管BPPV患者vHIT、cVEMP、oVEMP、ABR检查结果异常侧别分布情况比较,差异无统计学意义(P>0.05),但在老年水平半规管BPPV患者的oVEMP双侧异常率(41.2%)比后半规管BPPV患者的oVEMP双侧异常率(10.3%)高,两组差异存在统计学意义(P<0.05)。青中年BPPV患者的ABR双侧异常率(15.2%)低于老年BPPV患者的ABR双侧异常率(33.9%),差异存在统计学意义(P<0.05);青中年BPPV患者与老年BPPV患者vHIT、cVEMP、oVEMP检查结果异常侧别分布情况比较,差异无统计学意义(P>0.05)。结论BPPV可见于半规管弥漫性损伤,内耳循环障碍可引起耳石器功能障碍,其可能是BPPV的发病因素。

不同切口显微血管减压术治疗面肌痉挛的效果

目的分析不同切口显微血管减压术(MVD)治疗面肌痉挛(HFS)的效果。方法回顾性收集2019年6月至2023年11月周口市中心医院收治的97例HFS患者为研究对象,按照不同治疗方案分为两组,其中竖切口组(49例)接受竖切口MVD,横切口组(48例)接受耳后横切口MVD,观察两组手术基础指标、面部美观满意度、并发症状况以及围手术期疼痛视觉模拟量表(VAS)分值、脑干听觉诱发电位(BAEP)。结果与竖切口组相比,横切口组手术时长与切口长度较短,术中出血量较少(P<0.05)。术后12 h横切口组VAS评分均低于竖切口组,且改善幅度大于竖切口组(P<0.05)。横切口组术后12 h波间期、潜伏期以及波幅的BAEP均高于竖切口组(P<0.05)。横切口组并发症发生率低于竖切口组(P<0.05)。横切口组面部美观满意度高于竖切口组(P<0.05)。结论与竖切口相比,耳后横切口MVD治疗HFS效果确切,可明显改善手术效果,减轻术后疼痛度,增强BAEP,减少并发症,并提升面部美观度。

脑电图结果和脑干听觉诱发电位与急性脑干梗死患者吞咽功能障碍的关系探讨

目的:探讨急性脑干梗死患者吞咽功能障碍与脑电图结果和脑干听觉诱发电位之间的关系。方法:将2021年1月—2023年4月在厦门市仙岳医院接受治疗的80例急性脑干梗死患者纳入为观察组,并选取同期健康体检者80例纳入为对照组,纳入的160例研究对象均接受脑电图及脑干听觉诱发电位检查。分析两组脑干听觉诱发电位、脑电图检查异常率并进行组间比较;比较不同脑干听觉诱发电位表现的脑梗死患者吞咽困难及预后情况;比较不同脑电图表现的脑梗死患者吞咽困难及预后情况;比较不同预后情况的脑梗死患者脑干听觉诱发电位检查Ⅰ波、Ⅲ波、Ⅴ波、Ⅰ-Ⅲ波、Ⅲ-Ⅴ波。结果:观察组脑电图和脑干听觉诱发电位异常率均高于对照组(P<0.05)。与脑干听觉诱发电位异常患者比较,正常患者改良Rankin量表问卷(mRS)预后良好、吞咽困难情况较轻(P<0.05);与脑电图异常患者比较,正常患者吞咽困难情况较轻(P<0.05)。脑干听觉诱发电位检查预后良好患者Ⅰ波、Ⅲ波、Ⅴ波、Ⅰ-Ⅲ波、Ⅲ-Ⅴ波均低于预后不良患者(P<0.05)。结论:脑电图和脑干听觉诱发电位检查异常患者的预后情况较差,吞咽功能障碍情况较为严重。

脑干听觉诱发电位在孤独症谱系障碍患儿中的特征分析

目的:分析脑干听觉诱发电位(BAEP)在孤独症谱系障碍(ASD)患儿中的特征。方法:选取2020年1月—2023年1月厦门市仙岳医院收治的100例ASD患儿为观察组,另取同期体检健康儿童26例为对照组,对其BAEP检测结果进行统计。对观察组实施听觉统合训练,观察干预效果。结果:两组Ⅰ波与Ⅲ波潜伏期比较,差异无统计学意义(P>0.05),观察组Ⅴ波潜伏期长于对照组,差异有统计学意义(P<0.05)。两组Ⅰ波、Ⅲ波波间差比较,差异无统计学意义(P>0.05),观察组Ⅲ波、Ⅴ波,Ⅰ波、Ⅴ波波间差均大于对照组,差异有统计学意义(P<0.05)。治疗后2周、1个月,异常组孤独症治疗评定量表(ATEC)评分均低于非异常组,差异有统计学意义(P<0.05)。治疗前和治疗后2周,异常组儿童孤独症评定量表(CARS)评分均低于非异常组,差异有统计学意义(P<0.05);异常组治疗前和治疗后2周CARS评分差值均大于非异常组,差异有统计学意义(P<0.05)。结论:BAEP检测能够为ASD患儿诊断提供依据,且听觉统合训练对于BAEP异常患儿症状改善更为显著。

振幅整合脑电图在足月新生儿病理性黄疸脑损伤诊断中的应用价值分析

目的:探讨振幅整合脑电图在足月新生儿病理性黄疸(PJON)脑损伤诊断中的应用价值。方法:选取2021年1月—2023年6月泗洪县第一人民医院收治的79例足月PJON患儿作为研究对象,患儿均接受振幅整合脑电图与脑干听觉诱发电位检查,以实验室检查及影像学检查结果为“金标准”,比较振幅整合脑电图检查、脑干听觉诱发电位检查诊断足月PJON脑损伤的效能。结果:实验室检查及影像学检查结果显示,79例足月PJON患儿中,确诊脑损伤10例。振幅整合脑电图诊断足月PJON脑损伤的灵敏度、特异度、准确率高于脑干听觉诱发电位,差异有统计学意义(P<0.05)。结论:振幅整合脑电图检查诊断足月PJON脑损伤的灵敏度、特异度与准确率较高,能为临床诊治提供依据。

新生儿高胆红素血症脑干听觉诱发电位的临床应用分析

目的探讨新生儿高胆红素血症对听力的影响。方法对44例新生儿高胆红素血症患儿进行脑干听觉诱发电位(BAEP)检测,并选取32例健康无黄疸表现的新生儿为对照组。结果 44例新生儿高胆红素血症患儿BAEP异常率65.9%,明显高于对照组,且胆红素水平越高,BAEP异常率越高。29例BAEP异常患儿出院后随访复查大部分恢复。结论高胆红素血症可导致新生儿听力受损,高胆红素血症新生儿应早期行BAEP检测,如予早期积极干预,听力损害多能恢复正常。