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The Expression of the Apoptosis-Suppressive Gene bcl-2 in the Tissue of Colon Carcinoma 被引量:1
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作者 黄文广 姚璇 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2002年第3期218-220,共3页
The role of bcl 2 in the pathogenesis of colorectal tumor were studied. The exp ression of bcl 2 in the colorectal carcinoma and incisional edge tissue of tumo r was detected by using SABC method. The results showed... The role of bcl 2 in the pathogenesis of colorectal tumor were studied. The exp ression of bcl 2 in the colorectal carcinoma and incisional edge tissue of tumo r was detected by using SABC method. The results showed that the positive rate o f bcl 2 was 69.6 % in colorectal carcinoma and 47.6 % in the incisional edge ti ssue respectively, with the difference being very significant ( P =0.001). B cl 2 positive rate was associated with Dukes' stage, but had nothing to do with histological classification. It was concluded that bcl 2 might play a signific ant role in the development of colorectal carcinoma. 展开更多
关键词 colorectal carcinoma bcl 2 oncoprotein apop tosis IMMUNOHISTOCHEMISTRY
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