BACKGROUND The incidence and mortality rate of colorectal cancer progressively increase with age and become particularly prominent after the age of 50 years.Therefore,the population that is≥50 years in age requires l...BACKGROUND The incidence and mortality rate of colorectal cancer progressively increase with age and become particularly prominent after the age of 50 years.Therefore,the population that is≥50 years in age requires long-term and regular colonoscopies.Uncomfortable bowel preparation is the main reason preventing patients from undergoing regular colonoscopies.The standard bowel preparation regimen of 4-L polyethylene glycol(PEG)is effective but poorly tolerated.AIM To investigate an effective and comfortable bowel preparation regimen for hospitalized patients≥50 years in age.METHODS Patients were randomly assigned to group 1(2-L PEG+30-mL lactulose+a lowresidue diet)or group 2(4-L PEG).Adequate bowel preparation was defined as a Boston bowel preparation scale(BBPS)score of≥6,with a score of≥2 for each segment.Non-inferiority was prespecified with a margin of 10%.Additionally,the degree of comfort was assessed based on the comfort questionnaire.RESULTS The proportion of patients with a BBPS score of≥6 in group 1 was not significantly different from that in group 2,as demonstrated by intention-to-treat(91.2%vs 91.0%,P=0.953)and per-protocol(91.8%vs 91.0%,P=0.802)analyses.Furthermore,in patients≥75 years in age,the proportion of BBPS scores of≥6 in group 1 was not significantly different from that in group 2(90.9%vs 97.0%,P=0.716).Group 1 had higher comfort scores(8.85±1.162 vs 7.59±1.735,P<0.001),longer sleep duration(6.86±1.204 h vs 5.80±1.730 h,P<0.001),and fewer awakenings(1.42±1.183 vs 2.04±1.835,P=0.026)than group 2.CONCLUSION For hospitalized patients≥50 years in age,the bowel preparation regimen comprising 2-L PEG+30-mL lactulose+a low-residue diet produced a cleanse that was as effective as the 4-L PEG regimen and even provided better comfort.展开更多
BACKGROUND Hospice care plays an important role in improving the quality of life of advanced cancer patients,but controversy remains over whether age affects the attitudes of family members toward hospice care.AIM To ...BACKGROUND Hospice care plays an important role in improving the quality of life of advanced cancer patients,but controversy remains over whether age affects the attitudes of family members toward hospice care.AIM To investigate the attitudes of family members of advanced cancer patients of different ages toward hospice care.METHODS The study participants were 175 family members of patients with advanced cancer from January 2020 and October 2022.The participants were divided into youth(<40 years,n=65),middle-aged(40–60 years,n=59),and elderly(>60 years,n=51)groups.Researchers investigated and compared the degree of awareness regarding hospice care,attitudes,and whether the family members of patients would choose hospice care.RESULTS Among the family members of 175 patients,approximately 28%(49/175)were aware of hospice care.Awareness of hospice care,the proportion of hospice care acceptance and adaptation attitudes,and the proportion of those who chose hospice care in the youth group were higher in the middle-aged and elderly groups(P<0.05).No statistically significant difference was found in these three indicators between the middle-aged and elderly groups(P>0.05).Hospice care was chosen mainly to relieve pain and reduce unnecessary treatment,whereas the reasons for not choosing hospice care were mainly distrust and ethical concerns.CONCLUSION The family members of patients with advanced cancer had relatively low awareness of hospice care,while youth had a higher awareness of hospice care,acceptance,and adaptation attitudes,and were more willing to choose hospice care.展开更多
The Rauer Group is located on the eastern margin of the early Paleozoic Prydz Belt in East Antarctica,and the typical ultrahigh-temperature(UHT,>900℃)granulites outcrop on Mather Peninsula.However,the timing of UH...The Rauer Group is located on the eastern margin of the early Paleozoic Prydz Belt in East Antarctica,and the typical ultrahigh-temperature(UHT,>900℃)granulites outcrop on Mather Peninsula.However,the timing of UHT metamorphism and P–T path of the UHT granulites have long been debated,which is critical to understanding the tectonic nature and evolution history of the Prydz Belt.Thus,both a sapphirine-bearing UHT metapelitic granulite and a garnet-bearing UHT mafic granulite are selected for zircon SHRIMP U-Pb age dating.The results show that metamorphic zircon mantles yield weighted mean^(206)Pb/^(238)U ages of 918±29 Ma and 901±29 Ma for the metapelitic and mafic granulites,respectively,while zircon rims and newly grown zircons yield weighted mean^(206)Pb/^(238)U ages of 523±9 Ma and 532±11 Ma,respectively.These new zircon age data suggest that the UHT granulites may have experienced polymetamorphism,in which pre-peak prograde stage occurred in the early Neoproterozoic Grenvillian orogenesis(1000–900 Ma),whereas the UHT metamorphism occurred in the late Neoproterozoic to early Paleozoic Pan-African orogenesis(580–460 Ma).This implies that P–T path of the UHT granulites should consist of two separate high-grade metamorphic events including the Grenvillian and Pan-African events,which are supposed to be related to assembly of Rodinia and Gondwana supercontinents respectively,and hence the overprinting UHT metamorphic event may actually reflect an important intracontinental reworking.展开更多
研究锌离子络合法快速分离纯化荞麦壳黄酮工艺,并评价纯化组分对晚期糖基化终末产物(AGEs)生成的抑制活性。根据络合转化率和络合强度,将荞麦壳黄酮提取物(BHF)经过二次锌离子络合,分别获得荞麦壳黄酮中间提取物(IBHF)和荞麦壳高黄酮组...研究锌离子络合法快速分离纯化荞麦壳黄酮工艺,并评价纯化组分对晚期糖基化终末产物(AGEs)生成的抑制活性。根据络合转化率和络合强度,将荞麦壳黄酮提取物(BHF)经过二次锌离子络合,分别获得荞麦壳黄酮中间提取物(IBHF)和荞麦壳高黄酮组分(HBHF)。采用Box-Behnken响应曲面分析法优化获得IBHF组分的最佳工艺参数:乙酸锌与样品质量比2∶1,乙醇体积分数30%,氨水体积分数0.05%,室温反应10 min。在该条件下络合转化率为97.44%。IBHF组分经过二次锌离子络合,分离获得HBHF组分,其总黄酮含量为57.08 g RE/100 g(三氯化铝-乙酸盐比色法),其纯度比分离纯化前提高了6.64倍。高效液相色谱分析(HPLC)表明,HBHF组分含有异荭草素、牡荆素、异牡荆素、芦丁、山奈酚-3-O芸香糖苷5种主要黄酮,其中芦丁占比62.34%。HBHF组分表现出良好的抗AGEs活性,在质量浓度为200μg/mL时,Glu-BSA体系的中的AGEs抑制率为63.16%,MGO-BSA体系中的AGEs抑制率为42.98%,抑制率均显著优于阳性对照氨基胍。展开更多
Aiming at the problem of long time-consuming and low accuracy of existing age estimation approaches,a new age estimation method using Gabor feature fusion,and an improved atomic search algorithm for feature selection ...Aiming at the problem of long time-consuming and low accuracy of existing age estimation approaches,a new age estimation method using Gabor feature fusion,and an improved atomic search algorithm for feature selection is proposed.Firstly,texture features of five scales and eight directions in the face region are extracted by Gabor wavelet transform.The statistical histogram is introduced to encode and fuse the directional index with the largest feature value on Gabor scales.Secondly,a new hybrid feature selection algorithm chaotic improved atom search optimisation with simulated annealing(CIASO-SA)is presented,which is based on an improved atomic search algorithm and the simulated annealing algorithm.Besides,the CIASO-SA algorithm introduces a chaos mechanism during atomic initialisation,significantly improving the convergence speed and accuracy of the algorithm.Finally,a support vector machine(SVM)is used to get classification results of the age group.To verify the performance of the proposed algorithm,face images with three resolutions in the Adience dataset are tested.Using the Gabor real part fusion feature at 48�48 resolution,the average accuracy and 1-off accuracy of age classification exhibit a maximum of 60.4%and 85.9%,respectively.Obtained results prove the superiority of the proposed algorithm over the state-of-the-art methods,which is of great referential value for application to the mobile terminals.展开更多
BACKGROUND Cardiovascular disease(CVD)is a leading cause of morbidity and mortality worldwide,the global burden of which is rising.It is still unclear the extent to which prediabetes contributes to the risk of CVD in ...BACKGROUND Cardiovascular disease(CVD)is a leading cause of morbidity and mortality worldwide,the global burden of which is rising.It is still unclear the extent to which prediabetes contributes to the risk of CVD in various age brackets among adults.To develop a focused screening plan and treatment for Chinese adults with prediabetes,it is crucial to identify variations in the connection between prediabetes and the risk of CVD based on age.AIM To examine the clinical features of prediabetes and identify risk factors for CVD in different age groups in China.METHODS The cross-sectional study involved a total of 46239 participants from June 2007 through May 2008.A thorough evaluation was conducted.Individuals with prediabetes were categorized into two groups based on age.Chinese atherosclerotic CVD risk prediction model was employed to evaluate the risk of developing CVD over 10 years.Random forest was established in both age groups.SHapley Additive exPlanation method prioritized the importance of features from the perspective of assessment contribution.RESULTS In total,6948 people were diagnosed with prediabetes in this study.In prediabetes,prevalences of CVD were 5(0.29%)in the younger group and 148(2.85%)in the older group.Overall,11.11%of the younger group and 29.59% of the older group were intermediate/high-risk of CVD for prediabetes without CVD based on the Prediction for ASCVD Risk in China equation in ten years.In the younger age group,the 10-year risk of CVD was found to be more closely linked to family history of CVD rather than lifestyle,whereas in the older age group,resident status was more closely linked.CONCLUSION The susceptibility to CVD is age-specific in newly diagnosed prediabetes.It is necessary to develop targeted approaches for the prevention and management of CVD in adults across various age brackets.展开更多
Allelopathy is an important mechanism in Eucalyptus plantations that causes detrimental impacts on understory diversity.Phenolic compounds are the main allelochemicals suppressing understory plants.However,the dynamic...Allelopathy is an important mechanism in Eucalyptus plantations that causes detrimental impacts on understory diversity.Phenolic compounds are the main allelochemicals suppressing understory plants.However,the dynamic changes in phenolic allelochemicals and their relationship with understory diversity with increasing age of Eucalyptus plantations remain largely unclear.In this study,the understory plant diversity was assessed and phenolic compounds identified from leaf litter,roots,and rhizosphere soil samples in a Eucalyptus grandis plantation at two-year intervals for ten years using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).The abundance and diversity of under story plant species were lowest in 4-year-old plantations and increased significantly with age.Seven phenolic acids and 10 flavonoids were identified from leaf litter,roots,and rhizosphere soils.Most of the potential phenolic allelochemicals,such as salicylic acid,gallic acid,4-hydroxybenzoic acid,and epicatechin,were more abundant in younger plantations,especially at4 years old.The concentrations of phenolic compounds in the rhizosphere zone were significantly lower than in litter and root samples and did not change significantly with an increase in age.Notably,phenolic compounds contributed more to the variation in the understory plants than soil factors.Hydroxyphenyllactic acid,ellagic acid,quercetin,salicylic acid,and 4-hydroxybenzoic acid were the main phenolic compounds explaining the variation in plant diversity with plantation age.These findings indicate that young E.grandis plantations,especially at four years of age,merit a greater focus because of their lower understory plant diversity and higher allelopathic potential.展开更多
Ecological stoichiometry is an important indicator of biogeochemical cycles and nutrient limitations in terrestrial ecosystems.However,little is known about the response of ecological stoichiometry to plant growth.In ...Ecological stoichiometry is an important indicator of biogeochemical cycles and nutrient limitations in terrestrial ecosystems.However,little is known about the response of ecological stoichiometry to plant growth.In this study,carbon(C),nitrogen(N),and phosphorus(P)concentrations were evaluated in plant tissues(trees,shrubs,and herbs),litter,and soil of young(≤40-year-old),middle-aged(41–60-year-old),near-mature(61–80-year-old),and mature(81–120-year-old)Quercus secondary forests on the Loess Plateau,China.Vegetation composition,plant biomass,and C stock were determined to illustrate their interaction with stoichiometry.Only tree biomass C signifi cantly increased with stand development.Leaf N and trunk P concentrationsgenerally increased,but branch P decreased with growth stage.Fine roots had the highest C and P concentrations at the middle-aged stage.In contrast,shrubs,herbs,litter,and soil C:N:P stoichiometry did not change signifi cantly during stand development.Leaf N and P were positively correlated with soil C,N,P,and their ratios.However,there was no signifi cant correlation between litter and leaves in terms of C:N:P stoichiometry.A redundancy analysis showed that soil N best explained leaf N and P variance,and tree biomass and C stock were related to biotic factors such as tree age and shrub biomass.Hierarchical partitioning analysis indicated that,compared with soil or litter variables,stand age only accounted for a relatively small proportion of leaf C,N,and P variation.Thus,secondary Quercus ecosystems might have inherent ability to maintain sensitive responses of metabolically active organs to environmental factors during stand aging.The results of this work help to elucidate the biogeochemical cycling of secondary forest ecosystems in tree development,provide novel insights into the adaptation strategies of plants in diff erent organs and growth stages,and could be used to guide fertilization programs and optimize forest structure.展开更多
BACKGROUND No study has investigated the change regularity between age and subfoveal choroidal thickness(SFCT)in proliferative diabetic retinopathy(PDR).AIM To investigate the relationship between the SFCT and age in ...BACKGROUND No study has investigated the change regularity between age and subfoveal choroidal thickness(SFCT)in proliferative diabetic retinopathy(PDR).AIM To investigate the relationship between the SFCT and age in Chinese patients with PDR.METHODS This was a cross-sectional retrospective study.The participants were hospitalized individuals with type 2 diabetes who underwent vitrectomy for PDR.Contralateral eyes that met the criteria were included in the study.All necessary laboratory tests were performed at the time of admission.Central macular thickness(CMT)and SFCT were two quantitative assessments made using enhanced depth imaging optical coherence tomography.CMT was measured automatically and SFCT was measured manually with digital calipers provided by the Heidelberg Eye Explorer software.RESULTS The final analysis included a total of 234 individuals with PDR.The average age was 55.60 years old±10.03 years old,and 57.69%of the population was male.Univariate analysis revealed a significant negative connection between age and SFCT in patients with PDR[β=-2.44,95%confidence interval(95%CI):-3.46 to-1.42;P<0.0001].In the fully adjusted model,the correlation between SFCT and age remained steady(β=-1.68,95%CI:-2.97 to-0.39;P=0.0117).Spline smoothing showed that the relationship between SFCT and age in patients with PDR was non-linear,with an inflection point at 54 years of age.CONCLUSION Our findings suggest that age is a key determinant of choroidal thickness.The non-linear link between SFCT and age in PDR patients should be taken into account.展开更多
Haloxylon ammodendron, with its tolerance of drought, high temperature, and salt alkali conditions, is one of the main sand-fixing plant species in the oasis-desert transition zone in China. This study used the TDP30(...Haloxylon ammodendron, with its tolerance of drought, high temperature, and salt alkali conditions, is one of the main sand-fixing plant species in the oasis-desert transition zone in China. This study used the TDP30(where TDP is the thermal dissipation probe) to measure hourly and daily variations in the stem sap flow velocity of H. ammodendron at three age-classes(10, 15, and 20 years old,which were denoted as H10, H15, and H20, respectively) in the Minqin oasis-desert transition zone,China, from May through October 2020. By simultaneously monitoring temperature, relative humidity,photosynthetically active radiation, wind speed, net radiation, rainfall, and soil moisture in this region, we comprehensively investigated the stem sap flow velocity of different-aged H. ammodendron plants(H10,H15, and H20) and revealed its response to physical factors. The results showed that, on sunny days, the hourly variation curves of the stem sap flow velocity of H. ammodendron plants at the three age-classes were mainly unimodal. In addition, the stem sap flow velocity of H. ammodendron plants decreased significantly from September to October, which also delayed its peak time of hourly variation. On rainy days, the stem sap flow velocity of H. ammodendron plants was multimodal and significantly lower than that on sunny days.Average daily water consumption of H. ammodendron plants at H10, H15, and H20 was 1.98, 2.82, and 1.91kg/d, respectively. Temperature was the key factor affecting the stem sap flow velocity of H. ammodendron at all age-classes. Net radiation was the critical factor influencing the stem sap flow velocity of H.ammodendron at H10 and H15;however, for that at H20, it was vapor pressure deficit. The stem sap flow velocity of H. ammodendron was highly significantly correlated with soil moisture at the soil depths of 50and 100 cm, and the correlation was strengthened with increasing stand age. Altogether, our results revealed the dynamic changes of the stem sap flow velocity in different-aged H. ammodendron forest stands and its response mechanism to local physical factors, which provided a theoretical basis for the construction of new protective forests as well as the restoration and protection of existing ones in this region and other similar arid regions in the world.展开更多
Objective The Late Paleozoic Southern Tianshan Ocean is usually considered to be the last-closed ocean in the Tianshan Orogeny. However, there is still no consensus if this is indeed the case. Blueschist, eclogite an...Objective The Late Paleozoic Southern Tianshan Ocean is usually considered to be the last-closed ocean in the Tianshan Orogeny. However, there is still no consensus if this is indeed the case. Blueschist, eclogite and ophiolite are present in the Atbashi Range, Kyrgyzstan, which are believed to be the relics of the Southern Tianshan Ocean. New data obtained through Ar-Ar isotopic analysis in this research provide reliable chronological restrictions for this problem.展开更多
In the context of rising life expectancy,there is a significant discrepancy between Chinese seniors’self-perceptions of the start of old age and the expectations of society around this age.The traditional paradigm,wh...In the context of rising life expectancy,there is a significant discrepancy between Chinese seniors’self-perceptions of the start of old age and the expectations of society around this age.The traditional paradigm,which forecasts individual economic behavior and formulates economic policies based on societal standards of age,is put to the test by this disparity.This study,which draws from the China Longitudinal Aging Society Survey(CLASS),examines the factors,processes,and improvement strategies that affect how older people choose to work.The following are our conclusions:(i)Chinese elderly believe their old age starts from 70 years on average;delaying perceived old age is a denial of aging and raises the likelihood of finding work.Elders who are youthful at heart have a 2.4%higher chance of remaining employed than elders who are old at heart.(ii)In contrast to old-at-heart elders,young-at-heart elders are more likely to maintain their middle-age lifestyles,continue working,become motivated to engage in social activities,and gain the confidence to face challenges and continue in their career.(iii)If the perceived old age is above 70 years,the milestone event of aging is retirement from work,and there are external pressures,particularly pressures from family intergenerational support,the perception of old age will have a more proactive impact on older workers.(iv)Despite rising pension benefits,older people’s decision to remain in the workforce is still heavily influenced by their perception of their age.However,this effect is notably gender-specific,as older women’s decision to remain in the workforce is not greatly influenced by their own perception of their age.展开更多
We are writing in response to the paper published in the World Journal of Gastroenterology by Zhou et al.The authors identified higher serum immunoglobulin(Ig)G4 levels and age over 55 years as independent risk factor...We are writing in response to the paper published in the World Journal of Gastroenterology by Zhou et al.The authors identified higher serum immunoglobulin(Ig)G4 levels and age over 55 years as independent risk factors for disease relapse.Despite notable strengths,it is crucial to address potential biases.Firstly,the cohort study included 189 patients with autoimmune pancreatitis(AIP)type 1(with higher IgG4 seropositivity and higher relapse)and 24 with type 2(with lower IgG4 seropositivity and lower relapse).Consequently,most,if not all,AIP type 2 patients were assigned to the normal group,possibly inflating the association of higher serum IgG4 levels with relapse and potentially exaggerating the association of older age with relapse.Secondly,the authors did not provide sufficient details regarding AIP diagnosis,such as the ratio of definitive vs probable cases and the proportion of biopsies.In cases where histological evidence is unavailable or indeterminate,AIP type 2 may be misdiagnosed as definitive type 1,and type 1 may also be misdiagnosed as probable type 2,particularly in cases with normal or mildly elevated serum IgG4 levels.Lastly,in this retrospective study,approximately one-third of the consecutive patients initially collected were excluded for various reasons.Accordingly,the impact of nonrandom exclusion on relapse outcomes should be carefully considered.In conclusion,the paper by Zhou et al offers plausible,though not entirely compelling,evidence suggesting a predictive role of elevated serum IgG4 levels and advanced age in AIP relapse.The foundation for future investigations lies in ensuring a reliable diagnosis and accurate disease subtyping,heavily dependent on obtaining histological specimens.In this regard,endoscopic ultrasound-guided fine-needle biopsy emerges as a pivotal component of the diagnostic process,contributing to mitigating biases in future explorations of the disease.展开更多
The tendril is a climbing organ in cucurbits and functions in physical support and to avoid shading by neighboring vegetation.However,how cucurbits produce tendrils to obtain climbing ability is largely unknown.In thi...The tendril is a climbing organ in cucurbits and functions in physical support and to avoid shading by neighboring vegetation.However,how cucurbits produce tendrils to obtain climbing ability is largely unknown.In this study,tendril phenotypes were investigated during different developmental stages.Our results revealed that tendril growth exhibited an age-dependent pattern in cucurbits.Tendril growth was inhibited,and the tendril was formed as a short tendril[nonfunctional tendril(nonF-tendril),approximately 0.1 cm]during the seedling stage.In contrast,enhanced cell proliferation and cell expansion led to rapid elongation of the tendril during the climbing stage,and the tendril formed as a functional tendril(F-tendril,approximately 30 cm)to obtain climbing ability.RT-qPCR detection showed that age-dependent tendril growth correlated negatively with the abundance of the conserved age regulator CsmiR156.Defoliation induced CsmiR156 to inhibit CsSPLs,and F-tendril formation and climbing ability were delayed in defoliated cucumbers,which confirmed the role of CsmiR156 in regulating tendril growth in vivo.Additionally,exogenous gibberellin(GA)treatment showed that GA positively regulated tendril growth,and RT-qPCR detection showed that the GA bio-synthetic genes and metabolic genes were affected by age pathway,suggesting that the age pathway depended on GA bio-synthetic and metabolic pathway to regulate cell expansion to determine tendril growth.In summary,our work reveals that change in tendril type is an important marker of phase transition in cucumber,and tendril growth is regulated by an intrinsic developmental age signal,ensuring that the cucumber obtains climbing ability at a suitable age.展开更多
Land use change affects the balance of organic carbon(C)reserves and the global C cycle.Microbial residues are essential constituents of stable soil organic C(SOC).However,it remains unclear how microbial residue chan...Land use change affects the balance of organic carbon(C)reserves and the global C cycle.Microbial residues are essential constituents of stable soil organic C(SOC).However,it remains unclear how microbial residue changes over time following afforestation.In this study,16-,23-,52-,and 62-year-old Mongolian pine stands and 16-year-old cropland were studied in the Horqin Sandy Land,China.We analyzed changes in SOC,amino sugar content,and microbial parameters to assess how microbial communities influence soil C transformation and preservation.The results showed that SOC storage increased with stand age in the early stage of afforestation but remained unchanged at about 1.27-1.29 kg/m2 after 52 a.Moreover,there were consistent increases in amino sugars and microbial residues with increasing stand age.As stand age increased from 16 to 62 a,soil pH decreased from 6.84 to 5.71,and the concentration of total amino sugars increased from 178.53 to 509.99 mg/kg.A significant negative correlation between soil pH and the concentration of specific and total amino sugars was observed,indicating that the effects of soil acidification promote amino sugar stabilization during afforestation.In contrast to the Mongolian pine plantation of the same age,the cropland accumulated more SOC and microbial residues because of fertilizer application.Across Mongolian pine plantation with different ages,there was no significant change in calculated contribution of bacterial or fungal residues to SOC,suggesting that fungi were consistently the dominant contributors to SOC with increasing time.Our results indicate that afforestation in the Horqin Sandy Land promotes efficient microbial growth and residue accumulation in SOC stocks and has a consistent positive impact on SOC persistence.展开更多
Forest net primary productivity(NPP)constitutes a key flux within the terrestrial ecosystem carbon cycle and serves as a significant indicator of the forests carbon sequestration capacity,which is closely related to f...Forest net primary productivity(NPP)constitutes a key flux within the terrestrial ecosystem carbon cycle and serves as a significant indicator of the forests carbon sequestration capacity,which is closely related to forest age.Despite its significance,the impact of forest age on NPP is often ignored in future NPP projections.Here,we mapped forest age in Hunan Province at a 30-m resolution utilizing a combination of Landsat time series stack(LTSS),national forest inventory(NFI)data,and the relationships between height and age.Subsequently,NPP was derived from NFI data and the relationships between NPP and age was built for various forest types.Then forest NPP was predicted based on the NPP-age relationships under three future scenarios,assessing the impact of forest age on NPP.Our findings reveal substantial variations in forest NPP in Hunan Province under three future scenarios:under the age-only scenario,NPP peaks in 2041(133.56TgC·yr^(−1)),while NPP peaks three years later in 2044(141.14TgC·yr^(−1))under the natural development scenario.The maximum afforestation scenario exhibits the most rapid increase in NPP,with peaking in 2049(197.95TgC·yr^(−1)).However,with the aging of the forest,NPP is projected to then decrease by 7.54%,6.07%,and 7.47%in 2060,and 20.05%,19.74%,and 28.38%in 2100,respectively,compared to their peaks under the three scenarios.This indicates that forest NPP will continue to decline soon.Controlling the age structure of forests through selective logging,afforestation and reforestation,and encouraging natural regeneration after disturbance could mitigate this declining trend in forest NPP,but implications of these measures on the full forest carbon balance remain to be studied.Insights from the future multi-scenarios are expected to provide data to support sustainable forest management and national policy development,which will inform the achievement of carbon neutrality goals by 2060.展开更多
基金The study was approved by the Ethics Committee of Beijing Tongren Hospital Affiliated to Capital Medical University(Approval No.TRECKY2021-227).
文摘BACKGROUND The incidence and mortality rate of colorectal cancer progressively increase with age and become particularly prominent after the age of 50 years.Therefore,the population that is≥50 years in age requires long-term and regular colonoscopies.Uncomfortable bowel preparation is the main reason preventing patients from undergoing regular colonoscopies.The standard bowel preparation regimen of 4-L polyethylene glycol(PEG)is effective but poorly tolerated.AIM To investigate an effective and comfortable bowel preparation regimen for hospitalized patients≥50 years in age.METHODS Patients were randomly assigned to group 1(2-L PEG+30-mL lactulose+a lowresidue diet)or group 2(4-L PEG).Adequate bowel preparation was defined as a Boston bowel preparation scale(BBPS)score of≥6,with a score of≥2 for each segment.Non-inferiority was prespecified with a margin of 10%.Additionally,the degree of comfort was assessed based on the comfort questionnaire.RESULTS The proportion of patients with a BBPS score of≥6 in group 1 was not significantly different from that in group 2,as demonstrated by intention-to-treat(91.2%vs 91.0%,P=0.953)and per-protocol(91.8%vs 91.0%,P=0.802)analyses.Furthermore,in patients≥75 years in age,the proportion of BBPS scores of≥6 in group 1 was not significantly different from that in group 2(90.9%vs 97.0%,P=0.716).Group 1 had higher comfort scores(8.85±1.162 vs 7.59±1.735,P<0.001),longer sleep duration(6.86±1.204 h vs 5.80±1.730 h,P<0.001),and fewer awakenings(1.42±1.183 vs 2.04±1.835,P=0.026)than group 2.CONCLUSION For hospitalized patients≥50 years in age,the bowel preparation regimen comprising 2-L PEG+30-mL lactulose+a low-residue diet produced a cleanse that was as effective as the 4-L PEG regimen and even provided better comfort.
文摘BACKGROUND Hospice care plays an important role in improving the quality of life of advanced cancer patients,but controversy remains over whether age affects the attitudes of family members toward hospice care.AIM To investigate the attitudes of family members of advanced cancer patients of different ages toward hospice care.METHODS The study participants were 175 family members of patients with advanced cancer from January 2020 and October 2022.The participants were divided into youth(<40 years,n=65),middle-aged(40–60 years,n=59),and elderly(>60 years,n=51)groups.Researchers investigated and compared the degree of awareness regarding hospice care,attitudes,and whether the family members of patients would choose hospice care.RESULTS Among the family members of 175 patients,approximately 28%(49/175)were aware of hospice care.Awareness of hospice care,the proportion of hospice care acceptance and adaptation attitudes,and the proportion of those who chose hospice care in the youth group were higher in the middle-aged and elderly groups(P<0.05).No statistically significant difference was found in these three indicators between the middle-aged and elderly groups(P>0.05).Hospice care was chosen mainly to relieve pain and reduce unnecessary treatment,whereas the reasons for not choosing hospice care were mainly distrust and ethical concerns.CONCLUSION The family members of patients with advanced cancer had relatively low awareness of hospice care,while youth had a higher awareness of hospice care,acceptance,and adaptation attitudes,and were more willing to choose hospice care.
基金supported by the National Nature Science Foundation of China(Grant no.41972050).
文摘The Rauer Group is located on the eastern margin of the early Paleozoic Prydz Belt in East Antarctica,and the typical ultrahigh-temperature(UHT,>900℃)granulites outcrop on Mather Peninsula.However,the timing of UHT metamorphism and P–T path of the UHT granulites have long been debated,which is critical to understanding the tectonic nature and evolution history of the Prydz Belt.Thus,both a sapphirine-bearing UHT metapelitic granulite and a garnet-bearing UHT mafic granulite are selected for zircon SHRIMP U-Pb age dating.The results show that metamorphic zircon mantles yield weighted mean^(206)Pb/^(238)U ages of 918±29 Ma and 901±29 Ma for the metapelitic and mafic granulites,respectively,while zircon rims and newly grown zircons yield weighted mean^(206)Pb/^(238)U ages of 523±9 Ma and 532±11 Ma,respectively.These new zircon age data suggest that the UHT granulites may have experienced polymetamorphism,in which pre-peak prograde stage occurred in the early Neoproterozoic Grenvillian orogenesis(1000–900 Ma),whereas the UHT metamorphism occurred in the late Neoproterozoic to early Paleozoic Pan-African orogenesis(580–460 Ma).This implies that P–T path of the UHT granulites should consist of two separate high-grade metamorphic events including the Grenvillian and Pan-African events,which are supposed to be related to assembly of Rodinia and Gondwana supercontinents respectively,and hence the overprinting UHT metamorphic event may actually reflect an important intracontinental reworking.
文摘研究锌离子络合法快速分离纯化荞麦壳黄酮工艺,并评价纯化组分对晚期糖基化终末产物(AGEs)生成的抑制活性。根据络合转化率和络合强度,将荞麦壳黄酮提取物(BHF)经过二次锌离子络合,分别获得荞麦壳黄酮中间提取物(IBHF)和荞麦壳高黄酮组分(HBHF)。采用Box-Behnken响应曲面分析法优化获得IBHF组分的最佳工艺参数:乙酸锌与样品质量比2∶1,乙醇体积分数30%,氨水体积分数0.05%,室温反应10 min。在该条件下络合转化率为97.44%。IBHF组分经过二次锌离子络合,分离获得HBHF组分,其总黄酮含量为57.08 g RE/100 g(三氯化铝-乙酸盐比色法),其纯度比分离纯化前提高了6.64倍。高效液相色谱分析(HPLC)表明,HBHF组分含有异荭草素、牡荆素、异牡荆素、芦丁、山奈酚-3-O芸香糖苷5种主要黄酮,其中芦丁占比62.34%。HBHF组分表现出良好的抗AGEs活性,在质量浓度为200μg/mL时,Glu-BSA体系的中的AGEs抑制率为63.16%,MGO-BSA体系中的AGEs抑制率为42.98%,抑制率均显著优于阳性对照氨基胍。
文摘Aiming at the problem of long time-consuming and low accuracy of existing age estimation approaches,a new age estimation method using Gabor feature fusion,and an improved atomic search algorithm for feature selection is proposed.Firstly,texture features of five scales and eight directions in the face region are extracted by Gabor wavelet transform.The statistical histogram is introduced to encode and fuse the directional index with the largest feature value on Gabor scales.Secondly,a new hybrid feature selection algorithm chaotic improved atom search optimisation with simulated annealing(CIASO-SA)is presented,which is based on an improved atomic search algorithm and the simulated annealing algorithm.Besides,the CIASO-SA algorithm introduces a chaos mechanism during atomic initialisation,significantly improving the convergence speed and accuracy of the algorithm.Finally,a support vector machine(SVM)is used to get classification results of the age group.To verify the performance of the proposed algorithm,face images with three resolutions in the Adience dataset are tested.Using the Gabor real part fusion feature at 48�48 resolution,the average accuracy and 1-off accuracy of age classification exhibit a maximum of 60.4%and 85.9%,respectively.Obtained results prove the superiority of the proposed algorithm over the state-of-the-art methods,which is of great referential value for application to the mobile terminals.
基金Scientific Research Project of Hebei Administration of Traditional Chinese Medicine(2020136)Science Research Project of Hebei Education Department(ZD2022043)。
文摘BACKGROUND Cardiovascular disease(CVD)is a leading cause of morbidity and mortality worldwide,the global burden of which is rising.It is still unclear the extent to which prediabetes contributes to the risk of CVD in various age brackets among adults.To develop a focused screening plan and treatment for Chinese adults with prediabetes,it is crucial to identify variations in the connection between prediabetes and the risk of CVD based on age.AIM To examine the clinical features of prediabetes and identify risk factors for CVD in different age groups in China.METHODS The cross-sectional study involved a total of 46239 participants from June 2007 through May 2008.A thorough evaluation was conducted.Individuals with prediabetes were categorized into two groups based on age.Chinese atherosclerotic CVD risk prediction model was employed to evaluate the risk of developing CVD over 10 years.Random forest was established in both age groups.SHapley Additive exPlanation method prioritized the importance of features from the perspective of assessment contribution.RESULTS In total,6948 people were diagnosed with prediabetes in this study.In prediabetes,prevalences of CVD were 5(0.29%)in the younger group and 148(2.85%)in the older group.Overall,11.11%of the younger group and 29.59% of the older group were intermediate/high-risk of CVD for prediabetes without CVD based on the Prediction for ASCVD Risk in China equation in ten years.In the younger age group,the 10-year risk of CVD was found to be more closely linked to family history of CVD rather than lifestyle,whereas in the older age group,resident status was more closely linked.CONCLUSION The susceptibility to CVD is age-specific in newly diagnosed prediabetes.It is necessary to develop targeted approaches for the prevention and management of CVD in adults across various age brackets.
基金funded by the National Nature Science Foundation of China (No.32171775,31770671)。
文摘Allelopathy is an important mechanism in Eucalyptus plantations that causes detrimental impacts on understory diversity.Phenolic compounds are the main allelochemicals suppressing understory plants.However,the dynamic changes in phenolic allelochemicals and their relationship with understory diversity with increasing age of Eucalyptus plantations remain largely unclear.In this study,the understory plant diversity was assessed and phenolic compounds identified from leaf litter,roots,and rhizosphere soil samples in a Eucalyptus grandis plantation at two-year intervals for ten years using ultra-performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).The abundance and diversity of under story plant species were lowest in 4-year-old plantations and increased significantly with age.Seven phenolic acids and 10 flavonoids were identified from leaf litter,roots,and rhizosphere soils.Most of the potential phenolic allelochemicals,such as salicylic acid,gallic acid,4-hydroxybenzoic acid,and epicatechin,were more abundant in younger plantations,especially at4 years old.The concentrations of phenolic compounds in the rhizosphere zone were significantly lower than in litter and root samples and did not change significantly with an increase in age.Notably,phenolic compounds contributed more to the variation in the understory plants than soil factors.Hydroxyphenyllactic acid,ellagic acid,quercetin,salicylic acid,and 4-hydroxybenzoic acid were the main phenolic compounds explaining the variation in plant diversity with plantation age.These findings indicate that young E.grandis plantations,especially at four years of age,merit a greater focus because of their lower understory plant diversity and higher allelopathic potential.
基金supported by the National Nature Science Foundation of China(No.41977418 and 42130717)National Key R&D Program of China(2016YFC0501703 and 2017YFC0504605)CAS“Light of West China”Program(XAB201702).
文摘Ecological stoichiometry is an important indicator of biogeochemical cycles and nutrient limitations in terrestrial ecosystems.However,little is known about the response of ecological stoichiometry to plant growth.In this study,carbon(C),nitrogen(N),and phosphorus(P)concentrations were evaluated in plant tissues(trees,shrubs,and herbs),litter,and soil of young(≤40-year-old),middle-aged(41–60-year-old),near-mature(61–80-year-old),and mature(81–120-year-old)Quercus secondary forests on the Loess Plateau,China.Vegetation composition,plant biomass,and C stock were determined to illustrate their interaction with stoichiometry.Only tree biomass C signifi cantly increased with stand development.Leaf N and trunk P concentrationsgenerally increased,but branch P decreased with growth stage.Fine roots had the highest C and P concentrations at the middle-aged stage.In contrast,shrubs,herbs,litter,and soil C:N:P stoichiometry did not change signifi cantly during stand development.Leaf N and P were positively correlated with soil C,N,P,and their ratios.However,there was no signifi cant correlation between litter and leaves in terms of C:N:P stoichiometry.A redundancy analysis showed that soil N best explained leaf N and P variance,and tree biomass and C stock were related to biotic factors such as tree age and shrub biomass.Hierarchical partitioning analysis indicated that,compared with soil or litter variables,stand age only accounted for a relatively small proportion of leaf C,N,and P variation.Thus,secondary Quercus ecosystems might have inherent ability to maintain sensitive responses of metabolically active organs to environmental factors during stand aging.The results of this work help to elucidate the biogeochemical cycling of secondary forest ecosystems in tree development,provide novel insights into the adaptation strategies of plants in diff erent organs and growth stages,and could be used to guide fertilization programs and optimize forest structure.
基金Supported by the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYJC21025.
文摘BACKGROUND No study has investigated the change regularity between age and subfoveal choroidal thickness(SFCT)in proliferative diabetic retinopathy(PDR).AIM To investigate the relationship between the SFCT and age in Chinese patients with PDR.METHODS This was a cross-sectional retrospective study.The participants were hospitalized individuals with type 2 diabetes who underwent vitrectomy for PDR.Contralateral eyes that met the criteria were included in the study.All necessary laboratory tests were performed at the time of admission.Central macular thickness(CMT)and SFCT were two quantitative assessments made using enhanced depth imaging optical coherence tomography.CMT was measured automatically and SFCT was measured manually with digital calipers provided by the Heidelberg Eye Explorer software.RESULTS The final analysis included a total of 234 individuals with PDR.The average age was 55.60 years old±10.03 years old,and 57.69%of the population was male.Univariate analysis revealed a significant negative connection between age and SFCT in patients with PDR[β=-2.44,95%confidence interval(95%CI):-3.46 to-1.42;P<0.0001].In the fully adjusted model,the correlation between SFCT and age remained steady(β=-1.68,95%CI:-2.97 to-0.39;P=0.0117).Spline smoothing showed that the relationship between SFCT and age in patients with PDR was non-linear,with an inflection point at 54 years of age.CONCLUSION Our findings suggest that age is a key determinant of choroidal thickness.The non-linear link between SFCT and age in PDR patients should be taken into account.
基金supported by the National Natural Science Foundation of China Subsidization Project (32260425, 31860238)the Natural Science Foundation of Gansu Province, China (32060246, 21JR7RA733)。
文摘Haloxylon ammodendron, with its tolerance of drought, high temperature, and salt alkali conditions, is one of the main sand-fixing plant species in the oasis-desert transition zone in China. This study used the TDP30(where TDP is the thermal dissipation probe) to measure hourly and daily variations in the stem sap flow velocity of H. ammodendron at three age-classes(10, 15, and 20 years old,which were denoted as H10, H15, and H20, respectively) in the Minqin oasis-desert transition zone,China, from May through October 2020. By simultaneously monitoring temperature, relative humidity,photosynthetically active radiation, wind speed, net radiation, rainfall, and soil moisture in this region, we comprehensively investigated the stem sap flow velocity of different-aged H. ammodendron plants(H10,H15, and H20) and revealed its response to physical factors. The results showed that, on sunny days, the hourly variation curves of the stem sap flow velocity of H. ammodendron plants at the three age-classes were mainly unimodal. In addition, the stem sap flow velocity of H. ammodendron plants decreased significantly from September to October, which also delayed its peak time of hourly variation. On rainy days, the stem sap flow velocity of H. ammodendron plants was multimodal and significantly lower than that on sunny days.Average daily water consumption of H. ammodendron plants at H10, H15, and H20 was 1.98, 2.82, and 1.91kg/d, respectively. Temperature was the key factor affecting the stem sap flow velocity of H. ammodendron at all age-classes. Net radiation was the critical factor influencing the stem sap flow velocity of H.ammodendron at H10 and H15;however, for that at H20, it was vapor pressure deficit. The stem sap flow velocity of H. ammodendron was highly significantly correlated with soil moisture at the soil depths of 50and 100 cm, and the correlation was strengthened with increasing stand age. Altogether, our results revealed the dynamic changes of the stem sap flow velocity in different-aged H. ammodendron forest stands and its response mechanism to local physical factors, which provided a theoretical basis for the construction of new protective forests as well as the restoration and protection of existing ones in this region and other similar arid regions in the world.
基金sponsored by the China Geological Survey(grants No.1212011120335 and 12120114006201)
文摘Objective The Late Paleozoic Southern Tianshan Ocean is usually considered to be the last-closed ocean in the Tianshan Orogeny. However, there is still no consensus if this is indeed the case. Blueschist, eclogite and ophiolite are present in the Atbashi Range, Kyrgyzstan, which are believed to be the relics of the Southern Tianshan Ocean. New data obtained through Ar-Ar isotopic analysis in this research provide reliable chronological restrictions for this problem.
基金supported by the General Project of the National Social Science Fund of China(NSSFC)(Grant No.19BRK028)Humanities and Social Science Research Youth Fund Project of the Ministry of Education:“Study on the Trends and Management of Population Outflow in China’s Border Regions”(Grant No.21YJC840021).
文摘In the context of rising life expectancy,there is a significant discrepancy between Chinese seniors’self-perceptions of the start of old age and the expectations of society around this age.The traditional paradigm,which forecasts individual economic behavior and formulates economic policies based on societal standards of age,is put to the test by this disparity.This study,which draws from the China Longitudinal Aging Society Survey(CLASS),examines the factors,processes,and improvement strategies that affect how older people choose to work.The following are our conclusions:(i)Chinese elderly believe their old age starts from 70 years on average;delaying perceived old age is a denial of aging and raises the likelihood of finding work.Elders who are youthful at heart have a 2.4%higher chance of remaining employed than elders who are old at heart.(ii)In contrast to old-at-heart elders,young-at-heart elders are more likely to maintain their middle-age lifestyles,continue working,become motivated to engage in social activities,and gain the confidence to face challenges and continue in their career.(iii)If the perceived old age is above 70 years,the milestone event of aging is retirement from work,and there are external pressures,particularly pressures from family intergenerational support,the perception of old age will have a more proactive impact on older workers.(iv)Despite rising pension benefits,older people’s decision to remain in the workforce is still heavily influenced by their perception of their age.However,this effect is notably gender-specific,as older women’s decision to remain in the workforce is not greatly influenced by their own perception of their age.
文摘We are writing in response to the paper published in the World Journal of Gastroenterology by Zhou et al.The authors identified higher serum immunoglobulin(Ig)G4 levels and age over 55 years as independent risk factors for disease relapse.Despite notable strengths,it is crucial to address potential biases.Firstly,the cohort study included 189 patients with autoimmune pancreatitis(AIP)type 1(with higher IgG4 seropositivity and higher relapse)and 24 with type 2(with lower IgG4 seropositivity and lower relapse).Consequently,most,if not all,AIP type 2 patients were assigned to the normal group,possibly inflating the association of higher serum IgG4 levels with relapse and potentially exaggerating the association of older age with relapse.Secondly,the authors did not provide sufficient details regarding AIP diagnosis,such as the ratio of definitive vs probable cases and the proportion of biopsies.In cases where histological evidence is unavailable or indeterminate,AIP type 2 may be misdiagnosed as definitive type 1,and type 1 may also be misdiagnosed as probable type 2,particularly in cases with normal or mildly elevated serum IgG4 levels.Lastly,in this retrospective study,approximately one-third of the consecutive patients initially collected were excluded for various reasons.Accordingly,the impact of nonrandom exclusion on relapse outcomes should be carefully considered.In conclusion,the paper by Zhou et al offers plausible,though not entirely compelling,evidence suggesting a predictive role of elevated serum IgG4 levels and advanced age in AIP relapse.The foundation for future investigations lies in ensuring a reliable diagnosis and accurate disease subtyping,heavily dependent on obtaining histological specimens.In this regard,endoscopic ultrasound-guided fine-needle biopsy emerges as a pivotal component of the diagnostic process,contributing to mitigating biases in future explorations of the disease.
基金supported by the Natural Science Foundation of Zhejiang province(Grant Nos.LZ20C150001,LY21C150002)National Natural Science Foundation of China(Grant No.32202583).
文摘The tendril is a climbing organ in cucurbits and functions in physical support and to avoid shading by neighboring vegetation.However,how cucurbits produce tendrils to obtain climbing ability is largely unknown.In this study,tendril phenotypes were investigated during different developmental stages.Our results revealed that tendril growth exhibited an age-dependent pattern in cucurbits.Tendril growth was inhibited,and the tendril was formed as a short tendril[nonfunctional tendril(nonF-tendril),approximately 0.1 cm]during the seedling stage.In contrast,enhanced cell proliferation and cell expansion led to rapid elongation of the tendril during the climbing stage,and the tendril formed as a functional tendril(F-tendril,approximately 30 cm)to obtain climbing ability.RT-qPCR detection showed that age-dependent tendril growth correlated negatively with the abundance of the conserved age regulator CsmiR156.Defoliation induced CsmiR156 to inhibit CsSPLs,and F-tendril formation and climbing ability were delayed in defoliated cucumbers,which confirmed the role of CsmiR156 in regulating tendril growth in vivo.Additionally,exogenous gibberellin(GA)treatment showed that GA positively regulated tendril growth,and RT-qPCR detection showed that the GA bio-synthetic genes and metabolic genes were affected by age pathway,suggesting that the age pathway depended on GA bio-synthetic and metabolic pathway to regulate cell expansion to determine tendril growth.In summary,our work reveals that change in tendril type is an important marker of phase transition in cucumber,and tendril growth is regulated by an intrinsic developmental age signal,ensuring that the cucumber obtains climbing ability at a suitable age.
基金funded by the Fundamental Research Funds of Chinese Academy of Forestry(CAF)(CAFYBB2020QD002-2).
文摘Land use change affects the balance of organic carbon(C)reserves and the global C cycle.Microbial residues are essential constituents of stable soil organic C(SOC).However,it remains unclear how microbial residue changes over time following afforestation.In this study,16-,23-,52-,and 62-year-old Mongolian pine stands and 16-year-old cropland were studied in the Horqin Sandy Land,China.We analyzed changes in SOC,amino sugar content,and microbial parameters to assess how microbial communities influence soil C transformation and preservation.The results showed that SOC storage increased with stand age in the early stage of afforestation but remained unchanged at about 1.27-1.29 kg/m2 after 52 a.Moreover,there were consistent increases in amino sugars and microbial residues with increasing stand age.As stand age increased from 16 to 62 a,soil pH decreased from 6.84 to 5.71,and the concentration of total amino sugars increased from 178.53 to 509.99 mg/kg.A significant negative correlation between soil pH and the concentration of specific and total amino sugars was observed,indicating that the effects of soil acidification promote amino sugar stabilization during afforestation.In contrast to the Mongolian pine plantation of the same age,the cropland accumulated more SOC and microbial residues because of fertilizer application.Across Mongolian pine plantation with different ages,there was no significant change in calculated contribution of bacterial or fungal residues to SOC,suggesting that fungi were consistently the dominant contributors to SOC with increasing time.Our results indicate that afforestation in the Horqin Sandy Land promotes efficient microbial growth and residue accumulation in SOC stocks and has a consistent positive impact on SOC persistence.
基金financially supported by the National Natural Science Foundation of China(grant no.31770679)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(grant no.KYCX24_1252)the China Scholarship Council(grant no.202308320354).
文摘Forest net primary productivity(NPP)constitutes a key flux within the terrestrial ecosystem carbon cycle and serves as a significant indicator of the forests carbon sequestration capacity,which is closely related to forest age.Despite its significance,the impact of forest age on NPP is often ignored in future NPP projections.Here,we mapped forest age in Hunan Province at a 30-m resolution utilizing a combination of Landsat time series stack(LTSS),national forest inventory(NFI)data,and the relationships between height and age.Subsequently,NPP was derived from NFI data and the relationships between NPP and age was built for various forest types.Then forest NPP was predicted based on the NPP-age relationships under three future scenarios,assessing the impact of forest age on NPP.Our findings reveal substantial variations in forest NPP in Hunan Province under three future scenarios:under the age-only scenario,NPP peaks in 2041(133.56TgC·yr^(−1)),while NPP peaks three years later in 2044(141.14TgC·yr^(−1))under the natural development scenario.The maximum afforestation scenario exhibits the most rapid increase in NPP,with peaking in 2049(197.95TgC·yr^(−1)).However,with the aging of the forest,NPP is projected to then decrease by 7.54%,6.07%,and 7.47%in 2060,and 20.05%,19.74%,and 28.38%in 2100,respectively,compared to their peaks under the three scenarios.This indicates that forest NPP will continue to decline soon.Controlling the age structure of forests through selective logging,afforestation and reforestation,and encouraging natural regeneration after disturbance could mitigate this declining trend in forest NPP,but implications of these measures on the full forest carbon balance remain to be studied.Insights from the future multi-scenarios are expected to provide data to support sustainable forest management and national policy development,which will inform the achievement of carbon neutrality goals by 2060.