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E3泛素连接酶ARIH1功能的研究进展
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作者 李振荣(综述) 孙欣 +1 位作者 王盛羽 宋鸿(审校) 《医学研究与战创伤救治》 CAS 北大核心 2023年第11期1221-1226,共6页
ARIH1是一种新发现的E3泛素连接酶,属于RBR家族,具有多种生物学功能,并与许多疾病的发生发展密切相关,如参与调控癌组织的进展,抑制细菌病毒等的增殖,调节代谢等,但仍有很多功能及机制有待研究人员去挖掘和探索。文章旨在对近年ARIH1蛋... ARIH1是一种新发现的E3泛素连接酶,属于RBR家族,具有多种生物学功能,并与许多疾病的发生发展密切相关,如参与调控癌组织的进展,抑制细菌病毒等的增殖,调节代谢等,但仍有很多功能及机制有待研究人员去挖掘和探索。文章旨在对近年ARIH1蛋白的功能研究进展进行综述,为研究人员提供可能的研究方向和目标。 展开更多
关键词 ARIH1 RBR E3泛素连接酶 癌症 主动脉疾病 感染
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Nay or Jain Nyay 2: Logic of Atheism of Jain Dharm
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作者 Mahendra Kumar Jain Agam Jain 《Journal of Philosophy Study》 2016年第2期69-87,共19页
Ethos and logos of the Jain thought and practice (world view) is based on reality perceived by senses. Atheistic roots of Jain Dharm have nourished growth, maintained viability and vitality, and kept it relevant for... Ethos and logos of the Jain thought and practice (world view) is based on reality perceived by senses. Atheistic roots of Jain Dharm have nourished growth, maintained viability and vitality, and kept it relevant for over the last five millennia. Unlike Judeo-Christian-Islam or Brahminical faith, it does not rely on omniscient supreme or god. Its atheistic and anti-theistic thrust is generally known, yet its followers do not call themselves Nastik (non-believers). They emphasize action-consequence relations as guide for successful behaviors with ethical conduct. The basis of their arguments follows from the Jain logic (Saptbhangi Syad Nay) of evidence based inference with multiple orthogonal affirmed assertions (Jain 2011). It conserves information by acknowledging the remaining doubt in an inference. It does not assume binary complementation to force closure for deduction with incomplete knowledge which leads to self-reference and loss of information. This approach offers a rational and practical alternative to conundrum of western atheism even though its arguments are logical and consistent with available evidence. It also obviates need to extract religious morality from social mores. Objective truth and knowledge of established generalizations is necessary but not sufficient for subjective searches to shape desires and for what the future ought to be. 展开更多
关键词 ATHEISM Mahaveer (Mahavira) JAINISM Jains OMNISCIENCE NAY Jain Nyay Nyaya Tirthankar Arhat arihant conflict resolution nonviolence truthfulness Buddha (Buddh) nothingness (Shoonyata) limitations of binary logic logic of inference Saptbhangi Syad Nay
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