Objective:To compare the safety and effectiveness of lower extremity artery bypass grafting and endovascular angioplasty in the treatment of lower extremity arteriosclerosis obliterans in the elderly.Methods:The data ...Objective:To compare the safety and effectiveness of lower extremity artery bypass grafting and endovascular angioplasty in the treatment of lower extremity arteriosclerosis obliterans in the elderly.Methods:The data of 87 elderly patients with lower extremity arteriosclerosis obliterans treated in our hospital from August 2015 to August 2017 were analyzed retrospectively.According to the different treatment methods,they were divided into angioplasty group(n=45,intravascular angioplasty)and bypass grafting group(n=42,lower extremity artery bypass grafting).The success rate,hemodynamics of dorsalis pedis artery and nerve conduction of lower extremity were compared between the two groups Velocity,VAS score,late target vessel lumen loss(LLL),patency rate,restenosis rate,ankle brachial index(ABI)and clinical adverse events.Results:There was no significant difference between angioplasty group and bypass group(P>0.05).One month after operation,the hemodynamics of dorsalis pedis artery and nerve conduction velocity of lower limbs in the two groups were better than those before operation,the difference was statistically significant(P<0.05),but there was no significant difference between the two groups(P>0.05).The VAS score of the two groups was significantly lower than that of the preoperative group(P<0.05),but there was no significant difference between the two groups(P>0.05).The ABI of the two groups was significantly improved after operation,the difference was statistically significant(P<0.05),but there was no significant difference between the groups at each time point(P>0.05).There was no significant difference in LLL,patency rate and restenosis rate between the two groups(P>0.05).There was statistical difference in the incidence of complications between the two groups(P<0.05).During the follow-up period,no serious adverse events such as death or amputation occurred in both groups.Conclusion:Endovascular angioplasty and lower extremity artery bypass grafting have the same clinical effect in the treatment of elderly patients with lower extremity arteriosclerosis obliterans,which are safe and feasible.展开更多
目的比较药物洗脱支架(drug-eluting stents,DES)与金属裸支架(bare metal stent,BMS)治疗股腘动脉硬化闭塞症的临床疗效。方法回顾性分析郑州大学第五附属医院2020年10月至2021年6月收治的47例股腘动脉硬化闭塞症患者的临床资料,其中2...目的比较药物洗脱支架(drug-eluting stents,DES)与金属裸支架(bare metal stent,BMS)治疗股腘动脉硬化闭塞症的临床疗效。方法回顾性分析郑州大学第五附属医院2020年10月至2021年6月收治的47例股腘动脉硬化闭塞症患者的临床资料,其中24例行药物洗脱支架治疗(DES组),23例行金属裸支架治疗(BMS组),术后对比两组的近中期临床疗效。结果47例患者均顺利完成手术,未发生与手术相关的不良事件。DES组与BMS组相比,术后7 d、3个月两组患者ABI比较差异均无统计学意义,术后6、12、24个月DES组患者ABI增长值均高于BMS组(P<0.05)。术后6个月一期通畅率差异无统计学意义,术后12、24个月一期通畅率分别为(91.7%vs.65.2%、83.3%vs.56.5%,P<0.05)。术后DES组靶病变血运重建率明显低于BMS组有明显的优势(4.0%vs.26.1%,P<0.05)。结论DES治疗股腘动脉硬化闭塞症具有较好的近中期疗效,其临床疗效优于BMS治疗。展开更多
文摘Objective:To compare the safety and effectiveness of lower extremity artery bypass grafting and endovascular angioplasty in the treatment of lower extremity arteriosclerosis obliterans in the elderly.Methods:The data of 87 elderly patients with lower extremity arteriosclerosis obliterans treated in our hospital from August 2015 to August 2017 were analyzed retrospectively.According to the different treatment methods,they were divided into angioplasty group(n=45,intravascular angioplasty)and bypass grafting group(n=42,lower extremity artery bypass grafting).The success rate,hemodynamics of dorsalis pedis artery and nerve conduction of lower extremity were compared between the two groups Velocity,VAS score,late target vessel lumen loss(LLL),patency rate,restenosis rate,ankle brachial index(ABI)and clinical adverse events.Results:There was no significant difference between angioplasty group and bypass group(P>0.05).One month after operation,the hemodynamics of dorsalis pedis artery and nerve conduction velocity of lower limbs in the two groups were better than those before operation,the difference was statistically significant(P<0.05),but there was no significant difference between the two groups(P>0.05).The VAS score of the two groups was significantly lower than that of the preoperative group(P<0.05),but there was no significant difference between the two groups(P>0.05).The ABI of the two groups was significantly improved after operation,the difference was statistically significant(P<0.05),but there was no significant difference between the groups at each time point(P>0.05).There was no significant difference in LLL,patency rate and restenosis rate between the two groups(P>0.05).There was statistical difference in the incidence of complications between the two groups(P<0.05).During the follow-up period,no serious adverse events such as death or amputation occurred in both groups.Conclusion:Endovascular angioplasty and lower extremity artery bypass grafting have the same clinical effect in the treatment of elderly patients with lower extremity arteriosclerosis obliterans,which are safe and feasible.
文摘目的比较药物洗脱支架(drug-eluting stents,DES)与金属裸支架(bare metal stent,BMS)治疗股腘动脉硬化闭塞症的临床疗效。方法回顾性分析郑州大学第五附属医院2020年10月至2021年6月收治的47例股腘动脉硬化闭塞症患者的临床资料,其中24例行药物洗脱支架治疗(DES组),23例行金属裸支架治疗(BMS组),术后对比两组的近中期临床疗效。结果47例患者均顺利完成手术,未发生与手术相关的不良事件。DES组与BMS组相比,术后7 d、3个月两组患者ABI比较差异均无统计学意义,术后6、12、24个月DES组患者ABI增长值均高于BMS组(P<0.05)。术后6个月一期通畅率差异无统计学意义,术后12、24个月一期通畅率分别为(91.7%vs.65.2%、83.3%vs.56.5%,P<0.05)。术后DES组靶病变血运重建率明显低于BMS组有明显的优势(4.0%vs.26.1%,P<0.05)。结论DES治疗股腘动脉硬化闭塞症具有较好的近中期疗效,其临床疗效优于BMS治疗。
