An efficient synthesis of thiazines from the three component reactions between dialkyl acetylenedicarboxylates, arylisothio- cyanates and N-nucleophiles at room temperature in water as the solvent is described.
A series of 1 3-thiazolane derivatives have been synthesized via multicomponent reactions of activated acetylenes,primary amines and isothiocyanates in the presence of a catalytic amount of Nmethylimidazole under solv...A series of 1 3-thiazolane derivatives have been synthesized via multicomponent reactions of activated acetylenes,primary amines and isothiocyanates in the presence of a catalytic amount of Nmethylimidazole under solvent-free conditions.展开更多
文摘An efficient synthesis of thiazines from the three component reactions between dialkyl acetylenedicarboxylates, arylisothio- cyanates and N-nucleophiles at room temperature in water as the solvent is described.
文摘A series of 1 3-thiazolane derivatives have been synthesized via multicomponent reactions of activated acetylenes,primary amines and isothiocyanates in the presence of a catalytic amount of Nmethylimidazole under solvent-free conditions.