A new chiral polymer-metal complex, wool-osmium tetroxide(wool-OsO4) complex was prepared by a very simple method. This complex was found to be able to catalyze the asymmetric dihydroxylation of allylamine to get (R)-...A new chiral polymer-metal complex, wool-osmium tetroxide(wool-OsO4) complex was prepared by a very simple method. This complex was found to be able to catalyze the asymmetric dihydroxylation of allylamine to get (R)-(+)-3-amino-l, 2-propanediol. The experimental results showed that OsO4 content in the complex, reaction time, allylamine/OsO4 molar ratio all have great effects on the chemical and optical yields of product. Additionally, wool-OsO4 complex catalyst could be reused without remarkable change in optical catalytic activity.展开更多
The osmium tetroxide catalyzed asymmetric dihydroxylation of the(22E)- steroidal sidechain is described and an unexpected 8:1 ratio of(22R,23R)and (22S,23S)was obtained from the(22E,24S)-24-ethyl substituted sidechain.
The C-ll isomer of natural trihydroxyl sesquiterpene 5-epi-kudtriol has been synthesized starting from (+)-dihydrocarvone via asymmetric dihydroxylation as a key step.
（-）-7-Isopropyl-cis-l-amino-2-indanol, a key chiral auxiliary and ligand in the highly stereo-selective asymmetric 6π- azaelectrocyclization, has been prepared previously by two methods. Each however involved using...（-）-7-Isopropyl-cis-l-amino-2-indanol, a key chiral auxiliary and ligand in the highly stereo-selective asymmetric 6π- azaelectrocyclization, has been prepared previously by two methods. Each however involved using of one extreme condition, i.e. high temperature or high pressure, for the respective reaction. A modified reaction route employed mild condition for synthesis was presented in this report.展开更多
The latest and highly efficient asymmetric dihydroxylation was employed to create the chiral vicinal dihydroxy group of the title compound 1, which has been synthesized from phenylacetaldehyde through 6 steps with a t...The latest and highly efficient asymmetric dihydroxylation was employed to create the chiral vicinal dihydroxy group of the title compound 1, which has been synthesized from phenylacetaldehyde through 6 steps with a total yield of 61%.展开更多
文摘A new chiral polymer-metal complex, wool-osmium tetroxide(wool-OsO4) complex was prepared by a very simple method. This complex was found to be able to catalyze the asymmetric dihydroxylation of allylamine to get (R)-(+)-3-amino-l, 2-propanediol. The experimental results showed that OsO4 content in the complex, reaction time, allylamine/OsO4 molar ratio all have great effects on the chemical and optical yields of product. Additionally, wool-OsO4 complex catalyst could be reused without remarkable change in optical catalytic activity.
文摘The osmium tetroxide catalyzed asymmetric dihydroxylation of the(22E)- steroidal sidechain is described and an unexpected 8:1 ratio of(22R,23R)and (22S,23S)was obtained from the(22E,24S)-24-ethyl substituted sidechain.
文摘The C-ll isomer of natural trihydroxyl sesquiterpene 5-epi-kudtriol has been synthesized starting from (+)-dihydrocarvone via asymmetric dihydroxylation as a key step.
文摘（-）-7-Isopropyl-cis-l-amino-2-indanol, a key chiral auxiliary and ligand in the highly stereo-selective asymmetric 6π- azaelectrocyclization, has been prepared previously by two methods. Each however involved using of one extreme condition, i.e. high temperature or high pressure, for the respective reaction. A modified reaction route employed mild condition for synthesis was presented in this report.
文摘The latest and highly efficient asymmetric dihydroxylation was employed to create the chiral vicinal dihydroxy group of the title compound 1, which has been synthesized from phenylacetaldehyde through 6 steps with a total yield of 61%.
