Arteriovenous graft (AVG) is artificially made with graft for hemodialysis in the patients with renal failure. Stenosis in the arterial or venous anastomosis of AVG results in its malfunction. Here, we made an AVG hem...Arteriovenous graft (AVG) is artificially made with graft for hemodialysis in the patients with renal failure. Stenosis in the arterial or venous anastomosis of AVG results in its malfunction. Here, we made an AVG hemodynamic model with three different anastomotic angles (20°, 30°, 40°) and analyzed hemodynamic parameters such as velocity vectors, WSS and OSI in the arterial and venous anastomosis to find what helps in developing new surgical techniques to reduce stenosis in the anastomosis. Recirculation flow, low WSS and high OSI in the venous anastomosis were demonstrated in 30° and 40°?models, and recirculation flow, high WSS and high OSI in the arterial anastomosis were shown in all models. Conclusively, higher anastomosis angle in the venous anastomosis cause stenosis, but stenosis in the arterial anastomosis happens irregardless of anastomosis angle.展开更多
Objective To reduce the risk of surgical resection of giant arteriovenous malformation (AVM) (>6.0 cm) and prevent normal perfusion pressure breakthrough (NPPB) for lowering the postoperative mortality. Methods ...Objective To reduce the risk of surgical resection of giant arteriovenous malformation (AVM) (>6.0 cm) and prevent normal perfusion pressure breakthrough (NPPB) for lowering the postoperative mortality. Methods During the operation under barbiturate anesthesia, the proximal end of the feeding arteries were ligated at first, and 0.5 ml isobutyl 12 cyanoacrylate (IBCA) with 0.5 ml 5% glucose was injected into the vessels towards the AVM, then the malformed vessels were resected totally. Postoperative digital subtraction angiography of the four vessels was performed in all patients. Results 50 patients with giant AVM survived after operation, only 6 (12.0%) had transient neurological dysfunction and 44 (88.0%) recovered after a follow up of 6-36 months. No patient suffered from normal perfusion pressure breakthrough (NPPB). Conclusions The embolization could block the arteriovenous shunts sufficiently to decrease the blood flow away from the normal areas of the brain so as to prevent the incidence of intra and postoperative rebleeding, especially in NPPB. Therefore, the combination of intraoperative embolization with surgical resection is an effective strategy in the treatment of giant cerebral AVMs, which make it operable for those used to be regarded as inoperable cases.展开更多
文摘Arteriovenous graft (AVG) is artificially made with graft for hemodialysis in the patients with renal failure. Stenosis in the arterial or venous anastomosis of AVG results in its malfunction. Here, we made an AVG hemodynamic model with three different anastomotic angles (20°, 30°, 40°) and analyzed hemodynamic parameters such as velocity vectors, WSS and OSI in the arterial and venous anastomosis to find what helps in developing new surgical techniques to reduce stenosis in the anastomosis. Recirculation flow, low WSS and high OSI in the venous anastomosis were demonstrated in 30° and 40°?models, and recirculation flow, high WSS and high OSI in the arterial anastomosis were shown in all models. Conclusively, higher anastomosis angle in the venous anastomosis cause stenosis, but stenosis in the arterial anastomosis happens irregardless of anastomosis angle.
文摘Objective To reduce the risk of surgical resection of giant arteriovenous malformation (AVM) (>6.0 cm) and prevent normal perfusion pressure breakthrough (NPPB) for lowering the postoperative mortality. Methods During the operation under barbiturate anesthesia, the proximal end of the feeding arteries were ligated at first, and 0.5 ml isobutyl 12 cyanoacrylate (IBCA) with 0.5 ml 5% glucose was injected into the vessels towards the AVM, then the malformed vessels were resected totally. Postoperative digital subtraction angiography of the four vessels was performed in all patients. Results 50 patients with giant AVM survived after operation, only 6 (12.0%) had transient neurological dysfunction and 44 (88.0%) recovered after a follow up of 6-36 months. No patient suffered from normal perfusion pressure breakthrough (NPPB). Conclusions The embolization could block the arteriovenous shunts sufficiently to decrease the blood flow away from the normal areas of the brain so as to prevent the incidence of intra and postoperative rebleeding, especially in NPPB. Therefore, the combination of intraoperative embolization with surgical resection is an effective strategy in the treatment of giant cerebral AVMs, which make it operable for those used to be regarded as inoperable cases.
