针对光伏热斑因尺寸微小及分布不规则导致其难以被检测的问题,提出了一种基于改进YOLO第8大版(you only look once version 8 large,YOLOv8l)的高效检测算法。该算法对YOLOv8l模型的颈部网络进行了改进,引入了针对小尺寸目标的检测层,...针对光伏热斑因尺寸微小及分布不规则导致其难以被检测的问题,提出了一种基于改进YOLO第8大版(you only look once version 8 large,YOLOv8l)的高效检测算法。该算法对YOLOv8l模型的颈部网络进行了改进,引入了针对小尺寸目标的检测层,有效地提高了对微小目标的特征提取能力和检测准确性。同时,在主干网络中,传统的卷积模块被感受野注意力卷积(receptive-field attention convolution,RFAConv)模块所取代,借助改良的空间注意力机制,算法能够更集中地捕捉待检测目标的全局信息。此外,采用辅助边界框下更有效的交并比(inner-complete intersection over union,Inner-CIoU)损失函数替代原有的损失函数,模型在检测过程中能够更加灵活地调整辅助边框的大小,从而提升了检测精度。结果表明,改进YOLOv8l算法在红外光伏热斑图像检测中的精确率、召回率和平均精确率均值分别达到了90.4%、93.2%和94.8%,相较于原始YOLOv8l算法分别提升了3.4%、2.2%和2.3%。因此,该算法在光伏热斑检测领域展现出显著的优势。展开更多
Objective: To investigate the effect of SLC6A8 on the proliferation of liver cancer cells by regulating mitophagy through BNIP3L. Methods: The expression of the SLC6A8 gene in liver cancer tissues was analyzed using t...Objective: To investigate the effect of SLC6A8 on the proliferation of liver cancer cells by regulating mitophagy through BNIP3L. Methods: The expression of the SLC6A8 gene in liver cancer tissues was analyzed using the TCGA database, and its correlation with BNIP3L expression was assessed. RT-PCR and Western blot techniques were employed to detect the expression of SLC6A8 and BNIP3L in human liver cancer Huh-7 and Hep3B cells. Immunofluorescence labeling and CCK-8 assay were used to observe mitochondrial autophagy and cell proliferation rate in SLC6A8-overexpressing Huh-7 and Hep3B cells. Evaluate the proliferation rate of SLC6A8-overexpressing Huh-7 and Hep3B cells after silencing BNIP3L using the CCK-8 detection method. Results: SLC6A8 was significantly overexpressed in liver cancer tissues and positively correlated with BNIP3L expression. Overexpression of SLC6A8 significantly promoted mitochondrial autophagy and proliferation of Huh-7 and Hep3B cells. Additionally, SLC6A8 overexpression significantly enhanced the expression of BNIP3L mRNA and protein. Upon BNIP3L silencing, the proliferative effect of SLC6A8 overexpression on liver cancer cells was reversed. Conclusion: High expression of SLC6A8 in liver cancer tissues is positively correlated with BNIP3L, and overexpression of SLC6A8 promotes mitochondrial autophagy and liver cancer cell proliferation. Silencing BNIP3L can reverses the effect of overexpression of SLC6A8 on liver cancer cell proliferation. This provides new targets and strategies for the treatment of liver cancer.展开更多
文摘针对光伏热斑因尺寸微小及分布不规则导致其难以被检测的问题,提出了一种基于改进YOLO第8大版(you only look once version 8 large,YOLOv8l)的高效检测算法。该算法对YOLOv8l模型的颈部网络进行了改进,引入了针对小尺寸目标的检测层,有效地提高了对微小目标的特征提取能力和检测准确性。同时,在主干网络中,传统的卷积模块被感受野注意力卷积(receptive-field attention convolution,RFAConv)模块所取代,借助改良的空间注意力机制,算法能够更集中地捕捉待检测目标的全局信息。此外,采用辅助边界框下更有效的交并比(inner-complete intersection over union,Inner-CIoU)损失函数替代原有的损失函数,模型在检测过程中能够更加灵活地调整辅助边框的大小,从而提升了检测精度。结果表明,改进YOLOv8l算法在红外光伏热斑图像检测中的精确率、召回率和平均精确率均值分别达到了90.4%、93.2%和94.8%,相较于原始YOLOv8l算法分别提升了3.4%、2.2%和2.3%。因此,该算法在光伏热斑检测领域展现出显著的优势。
基金Research Fund for Young and Middle-aged Teachers'Basic Research Ability Promotion Project of Guangxi Universities in 2021(No.2021KY0539)。
文摘Objective: To investigate the effect of SLC6A8 on the proliferation of liver cancer cells by regulating mitophagy through BNIP3L. Methods: The expression of the SLC6A8 gene in liver cancer tissues was analyzed using the TCGA database, and its correlation with BNIP3L expression was assessed. RT-PCR and Western blot techniques were employed to detect the expression of SLC6A8 and BNIP3L in human liver cancer Huh-7 and Hep3B cells. Immunofluorescence labeling and CCK-8 assay were used to observe mitochondrial autophagy and cell proliferation rate in SLC6A8-overexpressing Huh-7 and Hep3B cells. Evaluate the proliferation rate of SLC6A8-overexpressing Huh-7 and Hep3B cells after silencing BNIP3L using the CCK-8 detection method. Results: SLC6A8 was significantly overexpressed in liver cancer tissues and positively correlated with BNIP3L expression. Overexpression of SLC6A8 significantly promoted mitochondrial autophagy and proliferation of Huh-7 and Hep3B cells. Additionally, SLC6A8 overexpression significantly enhanced the expression of BNIP3L mRNA and protein. Upon BNIP3L silencing, the proliferative effect of SLC6A8 overexpression on liver cancer cells was reversed. Conclusion: High expression of SLC6A8 in liver cancer tissues is positively correlated with BNIP3L, and overexpression of SLC6A8 promotes mitochondrial autophagy and liver cancer cell proliferation. Silencing BNIP3L can reverses the effect of overexpression of SLC6A8 on liver cancer cell proliferation. This provides new targets and strategies for the treatment of liver cancer.
