Auditory neuropathy (AN) was reported 30 years ago in 1979 when Davis and Hirsh presented the first case with normal or near normal hearing threshold but absent auditory brainstem responses.Many names have been given ...Auditory neuropathy (AN) was reported 30 years ago in 1979 when Davis and Hirsh presented the first case with normal or near normal hearing threshold but absent auditory brainstem responses.Many names have been given since then including paradoxical hearing loss,brainstem auditory processing syndrome,central auditory dysfunction,neural synchrony disorder or neural dyssynchrony.The term auditory neuropathy was first given by Sininger and colleagues in 1995.More and more AN articles have been published in recent years.The present short review and case report focus on the most important characteristics from a clinical point of view in order to let young physicians know AN,and consequently make correct diagnosis.展开更多
Most infants who are later diagnosed with autism show delayed speech and language and/or atypical language profile.There is a large body of research on abnormal speech and language in children with autism.However,audi...Most infants who are later diagnosed with autism show delayed speech and language and/or atypical language profile.There is a large body of research on abnormal speech and language in children with autism.However,auditory development has been relatively under-investigated in autism research,despite its inextricable relationship with language development and despite researchers'ability to detect abnormalities in brain development and behavior in early infancy.In this review,we synthesize research on auditory processing in the prenatal period through infancy and childhood in typically developing children,children at high risk for autism,and children diagnosed with autism.We conclude that there are clear neurobiological and behavioral links between abnormal auditory development and the deficits in social communication seen in autism.We then offer perspectives on the need for a systematic characterization of early auditory development in autism,and identified questions to be addressed in future research on the development of autism.展开更多
文摘Auditory neuropathy (AN) was reported 30 years ago in 1979 when Davis and Hirsh presented the first case with normal or near normal hearing threshold but absent auditory brainstem responses.Many names have been given since then including paradoxical hearing loss,brainstem auditory processing syndrome,central auditory dysfunction,neural synchrony disorder or neural dyssynchrony.The term auditory neuropathy was first given by Sininger and colleagues in 1995.More and more AN articles have been published in recent years.The present short review and case report focus on the most important characteristics from a clinical point of view in order to let young physicians know AN,and consequently make correct diagnosis.
基金supported by the National Natural Science Foundation of China(31900775,31571136)the SCNU Young Faculty Research Award(18KJ09)the Key Realm R&D Program of Guangdong Province(2019B030335001)。
文摘Most infants who are later diagnosed with autism show delayed speech and language and/or atypical language profile.There is a large body of research on abnormal speech and language in children with autism.However,auditory development has been relatively under-investigated in autism research,despite its inextricable relationship with language development and despite researchers'ability to detect abnormalities in brain development and behavior in early infancy.In this review,we synthesize research on auditory processing in the prenatal period through infancy and childhood in typically developing children,children at high risk for autism,and children diagnosed with autism.We conclude that there are clear neurobiological and behavioral links between abnormal auditory development and the deficits in social communication seen in autism.We then offer perspectives on the need for a systematic characterization of early auditory development in autism,and identified questions to be addressed in future research on the development of autism.
