To observe the effect of electro-acupuncture （EA） on auto regressive with exogenous input model （ARX-model） auditory evoked index （AAI） in patients anesthetized with different anesthetics. Methods： Forty-eight ...To observe the effect of electro-acupuncture （EA） on auto regressive with exogenous input model （ARX-model） auditory evoked index （AAI） in patients anesthetized with different anesthetics. Methods： Forty-eight adult patients undergoing scheduled surgical operation were enrolled and divided into two groups （24 in each group） according to the anesthetics applied, Group A was anesthetized with propofol sedation and Group B with Isoflurane-epidural anesthesia. Group A was subdivided into three groups of low, middle and high concentration of target effect-site of 1.0 μg/ml, 1.5 μg/ml and 2.0 μg/ml through target controlled infusion （TCI） and Group B into 3 subgroups of minimum alveolar effective concentration of isoflurane （0.4 MAC, 0.6 MAC and 0.8 MAC for B1, B2 and B3 subgroups） respectively, with 8 patients in every subgroup. EA on acupoints of Hegu （LI4） and Neiguan （P6） was applied on all the patients during anesthesia, and the change of AAI at various time points was recorded. Results： In the three subgroups of Group A, levels of AAI were significantly elevated in the first few minutes after EA, and significantly lowered 20 min after EA in subgroup A2. While in the subgroups of Group B, except the elevating in Group B11 - 2 rain after EA, levels of AAI remained unchanged at other time points. Conclusion： Pain response could be reflected by AAI during EA. EA could enhance the sedative effect of propofol in middle concentration, but its effect on isoflurane epidural anesthesia is insignificant.展开更多
Background: Hypnosis monitoring has been shown to reduce the incidence of awareness. A-line ARX-IndexTM (AAI) derived from auditory evoked potentials (AEP) represents as a numerical variable depth of anaesthesia. Obje...Background: Hypnosis monitoring has been shown to reduce the incidence of awareness. A-line ARX-IndexTM (AAI) derived from auditory evoked potentials (AEP) represents as a numerical variable depth of anaesthesia. Objectives: To study the efficacy of AEP as an indicator of anaesthetic depth and monitor intraoperative awareness in neurosurgical patients by using the AAI scale. Design: Prospective cohort study is used. Setting: The study is in Neurosurgical centre of Tertiary care hospital. Participants: Neurosurgical patients requiring general anaesthesia with duration of surgery between 90 - 150 minutes were enrolled for the study. Intervention: Patients in Group 1 (control) were monitored by conventional methods. Patients in Group 2 (study) underwent intraoperative monitoring by using the AEP monitor. Primary outcome: To study the efficacy of AEP monitoring and AAI index for monitoring the depth of anaesthesia and reducing the incidence of awareness. Results: There was no significant difference in the intraoperative haemodynamic responses measured between the two study groups (p > 0.5). There was no significant difference in the identification of intraoperative awareness by using conventional parameters between the two groups (p > 0.5). There was also a significantly faster time to recovery for patients in Group 2 (p < 0.05). Conclusion: Hypnosis monitoring using AEP monitor/AAI in neurosurgical patients under general anaesthesia did not show any significant difference in haemodynamic response and intraoperative awareness but had significant lower consumption of volatile anaesthetic with cost sparing effect and a faster recovery time as compared to conventional monitoring.展开更多
Objective： To investigate the influence of electroacupuncture on auditory evoked potential index （AAI） during propofol sedation. Methods： According to propofol effect site concentration, 24 patients for operation ...Objective： To investigate the influence of electroacupuncture on auditory evoked potential index （AAI） during propofol sedation. Methods： According to propofol effect site concentration, 24 patients for operation were randomly allocated to group 1 （1.0 μg/mL）, group 2 （1. 5μg/mL） and group 3 （2.0 μg/mL）. Propofol was administered intravenously, points Hegu （LI4） and Neiguan （PC6） were electro-acupunctured, and changes in AAI were recorded. Results： AAI significantly rose in all groups during the initial several minutes after electro-acupuncture and significantly fell in group 2 at 20 min after electro-acupuncture（P〈 0.05）.Conclusion： AAI can sensitively reflect pain response during electro-acupuncture and electro-acupuncture can strengthen propofol sedation at its medium concentration.展开更多
目的探讨维库溴铵肌松状态下听觉诱发电位指数（AAI）预测觉醒状态（Wakefulness）恢复与消失的可能性。方法选择14例美国麻醉医师协会（ASA）体格分级Ⅰ～Ⅱ级在单纯全麻下行择期手术的成年患者。以丙泊酚和维库溴铵诱导麻醉，气管插...目的探讨维库溴铵肌松状态下听觉诱发电位指数（AAI）预测觉醒状态（Wakefulness）恢复与消失的可能性。方法选择14例美国麻醉医师协会（ASA）体格分级Ⅰ～Ⅱ级在单纯全麻下行择期手术的成年患者。以丙泊酚和维库溴铵诱导麻醉，气管插管。采用孤立前臂技术判定觉醒状态的恢复与消失。觉醒状态恢复后，以每小时10mg／kg持续静注丙泊酚直至觉醒状态再次消失。使用A-liner^TM无创麻醉深度监护仪连续监测AAI。结果觉醒状态恢复前、后30s内和觉醒状态消失前、后30s内，AAI值分别为24．6±5．0、32．1±7．3、33．4±9．6和21．1±5．9。觉醒状态存在时AAI值明显大于觉醒状态消失后（P〈0．001）。预测觉醒状态恢复和消失的Pt值分别是0．786和0．864。观察者操作特性（ROC）曲线下面积为0．926（SE0．002，95％ CI 0．922—0．931）。觉醒状态恢复概率为5％、50％和95％的AAI值分别是19（4．96％）、29（50．25％）和39（95．14％）。结论AAI可以作为肌松状态下监测觉醒状态恢复和消失的指标，且监测消失过程可能更为可靠。展开更多
文摘To observe the effect of electro-acupuncture （EA） on auto regressive with exogenous input model （ARX-model） auditory evoked index （AAI） in patients anesthetized with different anesthetics. Methods： Forty-eight adult patients undergoing scheduled surgical operation were enrolled and divided into two groups （24 in each group） according to the anesthetics applied, Group A was anesthetized with propofol sedation and Group B with Isoflurane-epidural anesthesia. Group A was subdivided into three groups of low, middle and high concentration of target effect-site of 1.0 μg/ml, 1.5 μg/ml and 2.0 μg/ml through target controlled infusion （TCI） and Group B into 3 subgroups of minimum alveolar effective concentration of isoflurane （0.4 MAC, 0.6 MAC and 0.8 MAC for B1, B2 and B3 subgroups） respectively, with 8 patients in every subgroup. EA on acupoints of Hegu （LI4） and Neiguan （P6） was applied on all the patients during anesthesia, and the change of AAI at various time points was recorded. Results： In the three subgroups of Group A, levels of AAI were significantly elevated in the first few minutes after EA, and significantly lowered 20 min after EA in subgroup A2. While in the subgroups of Group B, except the elevating in Group B11 - 2 rain after EA, levels of AAI remained unchanged at other time points. Conclusion： Pain response could be reflected by AAI during EA. EA could enhance the sedative effect of propofol in middle concentration, but its effect on isoflurane epidural anesthesia is insignificant.
文摘Background: Hypnosis monitoring has been shown to reduce the incidence of awareness. A-line ARX-IndexTM (AAI) derived from auditory evoked potentials (AEP) represents as a numerical variable depth of anaesthesia. Objectives: To study the efficacy of AEP as an indicator of anaesthetic depth and monitor intraoperative awareness in neurosurgical patients by using the AAI scale. Design: Prospective cohort study is used. Setting: The study is in Neurosurgical centre of Tertiary care hospital. Participants: Neurosurgical patients requiring general anaesthesia with duration of surgery between 90 - 150 minutes were enrolled for the study. Intervention: Patients in Group 1 (control) were monitored by conventional methods. Patients in Group 2 (study) underwent intraoperative monitoring by using the AEP monitor. Primary outcome: To study the efficacy of AEP monitoring and AAI index for monitoring the depth of anaesthesia and reducing the incidence of awareness. Results: There was no significant difference in the intraoperative haemodynamic responses measured between the two study groups (p > 0.5). There was no significant difference in the identification of intraoperative awareness by using conventional parameters between the two groups (p > 0.5). There was also a significantly faster time to recovery for patients in Group 2 (p < 0.05). Conclusion: Hypnosis monitoring using AEP monitor/AAI in neurosurgical patients under general anaesthesia did not show any significant difference in haemodynamic response and intraoperative awareness but had significant lower consumption of volatile anaesthetic with cost sparing effect and a faster recovery time as compared to conventional monitoring.
文摘Objective： To investigate the influence of electroacupuncture on auditory evoked potential index （AAI） during propofol sedation. Methods： According to propofol effect site concentration, 24 patients for operation were randomly allocated to group 1 （1.0 μg/mL）, group 2 （1. 5μg/mL） and group 3 （2.0 μg/mL）. Propofol was administered intravenously, points Hegu （LI4） and Neiguan （PC6） were electro-acupunctured, and changes in AAI were recorded. Results： AAI significantly rose in all groups during the initial several minutes after electro-acupuncture and significantly fell in group 2 at 20 min after electro-acupuncture（P〈 0.05）.Conclusion： AAI can sensitively reflect pain response during electro-acupuncture and electro-acupuncture can strengthen propofol sedation at its medium concentration.
文摘目的探讨维库溴铵肌松状态下听觉诱发电位指数（AAI）预测觉醒状态（Wakefulness）恢复与消失的可能性。方法选择14例美国麻醉医师协会（ASA）体格分级Ⅰ～Ⅱ级在单纯全麻下行择期手术的成年患者。以丙泊酚和维库溴铵诱导麻醉，气管插管。采用孤立前臂技术判定觉醒状态的恢复与消失。觉醒状态恢复后，以每小时10mg／kg持续静注丙泊酚直至觉醒状态再次消失。使用A-liner^TM无创麻醉深度监护仪连续监测AAI。结果觉醒状态恢复前、后30s内和觉醒状态消失前、后30s内，AAI值分别为24．6±5．0、32．1±7．3、33．4±9．6和21．1±5．9。觉醒状态存在时AAI值明显大于觉醒状态消失后（P〈0．001）。预测觉醒状态恢复和消失的Pt值分别是0．786和0．864。观察者操作特性（ROC）曲线下面积为0．926（SE0．002，95％ CI 0．922—0．931）。觉醒状态恢复概率为5％、50％和95％的AAI值分别是19（4．96％）、29（50．25％）和39（95．14％）。结论AAI可以作为肌松状态下监测觉醒状态恢复和消失的指标，且监测消失过程可能更为可靠。
