We report herein an I2/Ph I(OAc)2catalytic system for the pragmatic construction of C–N bonds through C–H/N–H oxidative coupling protocol.Divergent pyrrolo[2,3-b]indoles were efficiently prepared via I2-catalyzed i...We report herein an I2/Ph I(OAc)2catalytic system for the pragmatic construction of C–N bonds through C–H/N–H oxidative coupling protocol.Divergent pyrrolo[2,3-b]indoles were efficiently prepared via I2-catalyzed intramolecular C–H amination reactions from(E/Z)-2-indolylenamines under metal-free conditions.Various functional groups are tolerated under mild reaction conditions and the resulting pyrrolo[2,3-b]indoles were obtained with mostly good to excellent yields.It was interesting to observe that both the(E)-and(Z)-isomers of the starting materials were efficiently transformed into the targeted product.The I+-mediated catalytic cycle was proposed based on mechanistic studies for this reaction.展开更多
In recent years, visible light-driven organic photochemical synthesis has attracted wide research interest from academic and industrial communities due to its features of green and sustainable chemistry. In this flour...In recent years, visible light-driven organic photochemical synthesis has attracted wide research interest from academic and industrial communities due to its features of green and sustainable chemistry. In this flourishing area, Chinese chemists have devoted great efforts to different aspects of synthetic chemistry. This review will summarize their representative work according to the following categories: C–H functionalization, synthesis of aromatic aza-heterocycles, asymmetric organic photochemical synthesis, transformations of small molecules and biomolecule-compatible reactions.展开更多
The reaction of a cyclic osmacarbyne complex with sodium azide led to the formation of a ring expansion-annulation product,a unique tetrazole annulated polycyclic metallacycle.The reaction proceeds by insertion of a n...The reaction of a cyclic osmacarbyne complex with sodium azide led to the formation of a ring expansion-annulation product,a unique tetrazole annulated polycyclic metallacycle.The reaction proceeds by insertion of a nitrogen atom into the metal carbon triple bond and the second azide participating in the[2+3]cycloaddition.The successful isolation and characterization of metalla-azirine complex and metallapyridinium derivative strongly validated the mechanism for the formation of the title complex.The work demonstrates a new strategy to enrich the varieties of aza-metallacyclic species.展开更多
基金the National Natural Science Foundation of China(No.21961015)the Natural Science Foundation of Jiangxi Province(No.20202ACBL203005)for financial supportthe support from the Jiangxi Provincial Education Department Graduate Student Innovation Fund(No.YC2021-S236)。
文摘We report herein an I2/Ph I(OAc)2catalytic system for the pragmatic construction of C–N bonds through C–H/N–H oxidative coupling protocol.Divergent pyrrolo[2,3-b]indoles were efficiently prepared via I2-catalyzed intramolecular C–H amination reactions from(E/Z)-2-indolylenamines under metal-free conditions.Various functional groups are tolerated under mild reaction conditions and the resulting pyrrolo[2,3-b]indoles were obtained with mostly good to excellent yields.It was interesting to observe that both the(E)-and(Z)-isomers of the starting materials were efficiently transformed into the targeted product.The I+-mediated catalytic cycle was proposed based on mechanistic studies for this reaction.
基金supported by the National Natural Science Foundation of China(21772052,21772053,21772129,21801176,21672099,21732003)Chinese Academy of Sciences(XDB20020200)
文摘In recent years, visible light-driven organic photochemical synthesis has attracted wide research interest from academic and industrial communities due to its features of green and sustainable chemistry. In this flourishing area, Chinese chemists have devoted great efforts to different aspects of synthetic chemistry. This review will summarize their representative work according to the following categories: C–H functionalization, synthesis of aromatic aza-heterocycles, asymmetric organic photochemical synthesis, transformations of small molecules and biomolecule-compatible reactions.
基金This research was supported by the National Natural Science Foundation of China(Nos.22071206,U1705254,21931002)the Natural Science Foundation of Fujian Province of China(No.2020J01025).
文摘The reaction of a cyclic osmacarbyne complex with sodium azide led to the formation of a ring expansion-annulation product,a unique tetrazole annulated polycyclic metallacycle.The reaction proceeds by insertion of a nitrogen atom into the metal carbon triple bond and the second azide participating in the[2+3]cycloaddition.The successful isolation and characterization of metalla-azirine complex and metallapyridinium derivative strongly validated the mechanism for the formation of the title complex.The work demonstrates a new strategy to enrich the varieties of aza-metallacyclic species.
