Azido 6 deoxy curdlan(ADC) was synthesized by a direct regioselective reaction of curdlan with triphenylphosphine, carbon tetrabromide and sodium azide(NaN 3) in DMF at room temperature. The structure of ADC was deter...Azido 6 deoxy curdlan(ADC) was synthesized by a direct regioselective reaction of curdlan with triphenylphosphine, carbon tetrabromide and sodium azide(NaN 3) in DMF at room temperature. The structure of ADC was determined by 13 C NMR, IR and elemental analysis.展开更多
Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegra-dability an...Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegra-dability and reactivity. Copolymerization of lactide with functionalized cyclic carbonate monomers proved to be an efficient way to functionalize aliphatic polyesters. However, random co-polyesters with pendent amino groups were seldom reported. This article reported a facile way to prepare aliphatic polyesters with random pendant azido and amino groups via Click reaction.展开更多
The development of azide migration reactions is a formidable challenge due to potential competition from side processes driven by the release of molecular nitrogen. Here, we show a novel neighbouring carbonyl group-as...The development of azide migration reactions is a formidable challenge due to potential competition from side processes driven by the release of molecular nitrogen. Here, we show a novel neighbouring carbonyl group-assisted sequential 1,2-azide and 1,4-oxygen migration reaction of α-vinyl azides for the efficient preparation of a range of α-azido ketones. This represents the first transformation of α-vinyl azides into α-azido ketones. Notable features of this method are its high efficiency, broad substrate scope, excellent functional group compatibility, and high yields. The computational studies gave a key insights into the regioselective 1,2-azide and 1,4-oxygen migrations assisted by the neighbouring carbonyl group. Further conversions into a variety of nitrogen-containing compounds demonstrated the synthetic utility of the α-azido ketone products. Preliminary mechanistic studies disclosed a novel reaction mechanism involving neighbouring carbonyl group-assisted sequential 1,2-azide and1,4-oxygen migrations.展开更多
Based on the reaction between the azido group and hydrogen sulfide （H2S）, BTN, an ofT-on fluorescent sensor was synthesized, which exhibited a 20-fold fluorescence enhancement upon addition of H2S, and a 5.6×10...Based on the reaction between the azido group and hydrogen sulfide （H2S）, BTN, an ofT-on fluorescent sensor was synthesized, which exhibited a 20-fold fluorescence enhancement upon addition of H2S, and a 5.6×10 8 mol/L detection limit can be reached in 10 min. To check its applicability, an easy prepared test paper strip of BTN was made for rapid and selective detection of hydrogen sulfide in red-wine samples, the detection limit is as low as 1 μmol/L.展开更多
文摘Azido 6 deoxy curdlan(ADC) was synthesized by a direct regioselective reaction of curdlan with triphenylphosphine, carbon tetrabromide and sodium azide(NaN 3) in DMF at room temperature. The structure of ADC was determined by 13 C NMR, IR and elemental analysis.
文摘Functionalized aliphatic polyesters, especially those with pendent hydroxyl, carboxyl and amino groups, have attracted much research interest in recent years due to their perfect biocompatibility, biodegra-dability and reactivity. Copolymerization of lactide with functionalized cyclic carbonate monomers proved to be an efficient way to functionalize aliphatic polyesters. However, random co-polyesters with pendent amino groups were seldom reported. This article reported a facile way to prepare aliphatic polyesters with random pendant azido and amino groups via Click reaction.
基金the National Natural Science Foundation of China(21871043)the Department of Science and Technology of Jilin Province(20180101185JC,20190701012GH)the Fundamental Research Funds for the Central Universities(2412019ZD001).
文摘The development of azide migration reactions is a formidable challenge due to potential competition from side processes driven by the release of molecular nitrogen. Here, we show a novel neighbouring carbonyl group-assisted sequential 1,2-azide and 1,4-oxygen migration reaction of α-vinyl azides for the efficient preparation of a range of α-azido ketones. This represents the first transformation of α-vinyl azides into α-azido ketones. Notable features of this method are its high efficiency, broad substrate scope, excellent functional group compatibility, and high yields. The computational studies gave a key insights into the regioselective 1,2-azide and 1,4-oxygen migrations assisted by the neighbouring carbonyl group. Further conversions into a variety of nitrogen-containing compounds demonstrated the synthetic utility of the α-azido ketone products. Preliminary mechanistic studies disclosed a novel reaction mechanism involving neighbouring carbonyl group-assisted sequential 1,2-azide and1,4-oxygen migrations.
基金This work was financially supported by the Scien- tific Research Foundation of Northwest A＆F University （Nos. Z111021103 and Z111021107）, the National Nat- ural Science Foundation of China （Nos. 21206137, 21272030, 201205095, 21472016）, and Shaanxi Prov- ince Science and Technology （No. 2013K12-03-23）.
文摘Based on the reaction between the azido group and hydrogen sulfide （H2S）, BTN, an ofT-on fluorescent sensor was synthesized, which exhibited a 20-fold fluorescence enhancement upon addition of H2S, and a 5.6×10 8 mol/L detection limit can be reached in 10 min. To check its applicability, an easy prepared test paper strip of BTN was made for rapid and selective detection of hydrogen sulfide in red-wine samples, the detection limit is as low as 1 μmol/L.
