为提升涡轮叶片缘板阻尼器设计水平,对比B-G(blade to ground)型阻尼器和切向无约束B-B(blade to blade)型阻尼器结构,提出了一种基于刚度设计的B-B型缘板阻尼器结构。在动力学建模中重点分析了相邻叶片缘板和阻尼器之间总的正压力随阻...为提升涡轮叶片缘板阻尼器设计水平,对比B-G(blade to ground)型阻尼器和切向无约束B-B(blade to blade)型阻尼器结构,提出了一种基于刚度设计的B-B型缘板阻尼器结构。在动力学建模中重点分析了相邻叶片缘板和阻尼器之间总的正压力随阻尼器与左、右叶片缘板间相对运动在左、右缘板间的分配,给出了基于阻尼器运动的正压力分配方法;通过数值仿真分析了正压力分配对系统振动响应的影响,并重点讨论了阻尼器刚度、外激励相位差、正压力以及外激励幅值对系统减振特性的影响。仿真结果表明,在左、右叶片缘板与阻尼器完全粘滞和左、右叶片相对阻尼器对称同步振动的工况下可以将正压力按照平均分配处理;相比于切向无约束的B-B型阻尼器和刚性的B-G型阻尼器,所提出的基于刚度设计的缘板阻尼结构具有更优的减振性能。因此,研究结果提升了涡轮叶片缘板阻尼器接触正压力计算的准确性,拓展了阻尼器设计思路,可为同类阻尼器设计提供理论和工程参考。展开更多
DNA and its conformational transition can be used to design nanometer-scale structures, nano-tweezers and nanomechanical devices. Experiments and molecular simulations have been used to study the concentration effect ...DNA and its conformational transition can be used to design nanometer-scale structures, nano-tweezers and nanomechanical devices. Experiments and molecular simulations have been used to study the concentration effect on the A-DNA→B-DNA conformational transition, but a systematical investigation on counterion effect on the dynamics of this transition has not been reported up to now. In present work, restrained and unrestrained molecular dynamics (MD) simulations have been performed to characterize the stability of DNA conformations and the dynamics of A-DNA→B-DNA transitions in aqueous solutions with different alkali metal counterions. The DNA duplex d(CGCGAATTCGCG)2, coion Cl- and counterions Li+, Na+, K+, Rb+ and Cs~ as well as water molecule were considered using the PARM99 force field in the AMBER8 package. It was found that B-form DNA is more stable than A-form DNA in aqueous electrolyte solutions with different alkali metal counterions. In- creasing KCI concentration in solution hinders the A-DNA^B-DNA transition and the transition times for different alkali metal counterions conform to neither the simple sequence related to naked ion size nor to hydrated diameter, but an apparently abnormal sequence of K+ 〈 Rb+ 〈 Cs+ 〈 Na+ 〈 Li+. This abnormal sequence can be well understood in terms of an electrostatic model based on the effective cation diameters and the modified mean-spherical approximation (MMSA). The present results provide valuable information for the design of DNA-based nanomaterials and nanodevices.展开更多
Unrestrained molecular dynamics (MD) simulations have been carded out to characterize the stability of DNA conformations and the dynamics of A-DNA^B-DNA conformational transitions in aqueous RbC1 solutions. The PARM...Unrestrained molecular dynamics (MD) simulations have been carded out to characterize the stability of DNA conformations and the dynamics of A-DNA^B-DNA conformational transitions in aqueous RbC1 solutions. The PARM99 force field in the AMBER8 package was used to investigate the effect of RbC1 concentration on the dynamics of the A^B conformational tran- sition in the DNA duplex d(CGCGAATTCGCG)2. Canonical A- and B-form DNA were assumed for the initial conformation and the final conformation had a length per complete turn that matched the canonical B-DNA. The DNA structure was moni- tored for 3.0 ns and the distances between the C5' atoms were obtained from the simulations. It was found that all of the double stranded DNA strands of A-DNA converged to the structure of B-form DNA within 1.0 ns during the unrestrained MD simula- tions. In addition, increasing the RbC1 concentration in aqueous solution hindered the A^B conformational transition and the transition in aqueous RbC1 solution was faster than that in aqueous NaC1 solution for the same electrolyte strength. The effects of the types and concentrations of counterions on the dynamics of the A^B conformational transition can be understood in terms of the variation in water activity and the number of accumulated counterions in the major grooves of A-DNA. The ru- bidium ion distributions around both fixed A-DNA and B-DNA were obtained using the restrained MD simulations to help ex- plain the effect of RbC1 concentration on the dynamics of the A^B conformational transition.展开更多
The Cauchy problem to the Oldroyd-B model is studied.In particular,it is shown that if the smooth solution (u,τ) to this system blows up at a finite time T~*,then 0~T~*u(t) L∞dt = ∞.Furthermore,the global ...The Cauchy problem to the Oldroyd-B model is studied.In particular,it is shown that if the smooth solution (u,τ) to this system blows up at a finite time T~*,then 0~T~*u(t) L∞dt = ∞.Furthermore,the global existence of smooth solution to this system is given with small initial data.展开更多
文摘为提升涡轮叶片缘板阻尼器设计水平,对比B-G(blade to ground)型阻尼器和切向无约束B-B(blade to blade)型阻尼器结构,提出了一种基于刚度设计的B-B型缘板阻尼器结构。在动力学建模中重点分析了相邻叶片缘板和阻尼器之间总的正压力随阻尼器与左、右叶片缘板间相对运动在左、右缘板间的分配,给出了基于阻尼器运动的正压力分配方法;通过数值仿真分析了正压力分配对系统振动响应的影响,并重点讨论了阻尼器刚度、外激励相位差、正压力以及外激励幅值对系统减振特性的影响。仿真结果表明,在左、右叶片缘板与阻尼器完全粘滞和左、右叶片相对阻尼器对称同步振动的工况下可以将正压力按照平均分配处理;相比于切向无约束的B-B型阻尼器和刚性的B-G型阻尼器,所提出的基于刚度设计的缘板阻尼结构具有更优的减振性能。因此,研究结果提升了涡轮叶片缘板阻尼器接触正压力计算的准确性,拓展了阻尼器设计思路,可为同类阻尼器设计提供理论和工程参考。
基金supported by the National Natural Science Foundation of China(21176132 and 20876083)Specialized Research Fund for the Doctoral Program of Higher Education(20100002110024)
文摘DNA and its conformational transition can be used to design nanometer-scale structures, nano-tweezers and nanomechanical devices. Experiments and molecular simulations have been used to study the concentration effect on the A-DNA→B-DNA conformational transition, but a systematical investigation on counterion effect on the dynamics of this transition has not been reported up to now. In present work, restrained and unrestrained molecular dynamics (MD) simulations have been performed to characterize the stability of DNA conformations and the dynamics of A-DNA→B-DNA transitions in aqueous solutions with different alkali metal counterions. The DNA duplex d(CGCGAATTCGCG)2, coion Cl- and counterions Li+, Na+, K+, Rb+ and Cs~ as well as water molecule were considered using the PARM99 force field in the AMBER8 package. It was found that B-form DNA is more stable than A-form DNA in aqueous electrolyte solutions with different alkali metal counterions. In- creasing KCI concentration in solution hinders the A-DNA^B-DNA transition and the transition times for different alkali metal counterions conform to neither the simple sequence related to naked ion size nor to hydrated diameter, but an apparently abnormal sequence of K+ 〈 Rb+ 〈 Cs+ 〈 Na+ 〈 Li+. This abnormal sequence can be well understood in terms of an electrostatic model based on the effective cation diameters and the modified mean-spherical approximation (MMSA). The present results provide valuable information for the design of DNA-based nanomaterials and nanodevices.
基金support from the National Natural Science Foundation of China (21176132)the Specialized Research Fund for the Doctoral Program of Higher Education (2010000211024)
文摘Unrestrained molecular dynamics (MD) simulations have been carded out to characterize the stability of DNA conformations and the dynamics of A-DNA^B-DNA conformational transitions in aqueous RbC1 solutions. The PARM99 force field in the AMBER8 package was used to investigate the effect of RbC1 concentration on the dynamics of the A^B conformational tran- sition in the DNA duplex d(CGCGAATTCGCG)2. Canonical A- and B-form DNA were assumed for the initial conformation and the final conformation had a length per complete turn that matched the canonical B-DNA. The DNA structure was moni- tored for 3.0 ns and the distances between the C5' atoms were obtained from the simulations. It was found that all of the double stranded DNA strands of A-DNA converged to the structure of B-form DNA within 1.0 ns during the unrestrained MD simula- tions. In addition, increasing the RbC1 concentration in aqueous solution hindered the A^B conformational transition and the transition in aqueous RbC1 solution was faster than that in aqueous NaC1 solution for the same electrolyte strength. The effects of the types and concentrations of counterions on the dynamics of the A^B conformational transition can be understood in terms of the variation in water activity and the number of accumulated counterions in the major grooves of A-DNA. The ru- bidium ion distributions around both fixed A-DNA and B-DNA were obtained using the restrained MD simulations to help ex- plain the effect of RbC1 concentration on the dynamics of the A^B conformational transition.
文摘The Cauchy problem to the Oldroyd-B model is studied.In particular,it is shown that if the smooth solution (u,τ) to this system blows up at a finite time T~*,then 0~T~*u(t) L∞dt = ∞.Furthermore,the global existence of smooth solution to this system is given with small initial data.