A Study on the Temperature Correlation of B-mode Ultrasonic Image Gray for Noninvasive Temperature Monitoring in Hyperthermia

This paper deals with the temperature correlation of gray scale of B-mode ultrasound image from heated tissue. In this study, many in-vitro fresh pig livers are heated in a temperature range from 28 ℃ to 45℃, from which a series of B-mode ultrasonic images of livers were obtained. The gray-value is evaluated from the ultrasound images respectively. A correlation of the mean gray value of the selected regions (12×12 pixels) in B-mode ultrasonic images of liver and its temperature was pointed out. And the experiment results agreed the evaluation well. And it is possible to monitor the tissue temperature changing in hyperthermia using this correlation.

超声B-Mode Ratio对糖尿病患者颌下腺脂肪沉积的诊断效能

为了对比评价超声B-mode ratio及MR-IP-OP两种检查方法对糖尿病患者颌下腺脂肪沉积的诊断效能。选取志愿者174人(糖尿病患者89人和健康志愿者85人),利用超声B-mode ratio技术和3D MR-IP-OP方法评估和检测颌下腺的脂肪含量。使用独立样本t检验比较两组患者B-radio和MRI-IP-OP的FF值组间差异。采用受试者工作特征曲线(ROC)分析两种技术对颌下腺脂肪沉积的诊断效能。用Spear-man相关系数评价两组参数之间的相关性。糖尿病组的B-mode ratio值(1.337±0.128)明显高于正常组(0.917±0.138)。糖尿病组MR-IP-OP的FF值(21.88±7.86%)明显高于正常组(8.87±3.09%)。ROC曲线表明脂肪沉积评价中B-mode ratio和3D MR-IP-OP的曲线下面积(AUC)分别为0.860和0.909,超声B-mode ratio和3D MR-IP-OP方法获得的结果间有良好相关性(r=0.502,p<0.001)。超声B-mode ratio对颌下腺脂肪变性的诊断具有良好的诊断效能,可以替代MR-IP-OP检查技术,并且有很好的临床应用前景。

Clinical significance of B-mode ultrasound found bladder trabeculation in BPH patients

Objective To study the role of bladder trabeculation found by B-mode ultrasound in evaluating the degree of bladder outlet obstruction ( BOO ) and the bladder function in benign prostatic hyperplasia ( BPH) patients. Methods Conducted prospective research to determine differences in clinical data and urodynamic

Application and prospects of AI-based radiomics in ultrasound diagnosis

Artificial intelligence (AI)-based radiomics has attracted considerable research attention in the field of medical imaging, including ultrasound diagnosis. Ultrasound imaging has unique advantages such as high temporal resolution, low cost, and no radiation exposure. This renders it a preferred imaging modality for several clinical scenarios. This review includes a detailed introduction to imaging modalities, including Brightness-mode ultrasound, color Doppler flow imaging, ultrasound elastography, contrast-enhanced ultrasound, and multi-modal fusion analysis. It provides an overview of the current status and prospects of AI-based radiomics in ultrasound diagnosis, highlighting the application of AI-based radiomics to static ultrasound images, dynamic ultrasound videos, and multi-modal ultrasound fusion analysis.

Pre-Trained Deep Neural Network-Based Computer-Aided Breast Tumor Diagnosis Using ROI Structures

Deep neural network(DNN)based computer-aided breast tumor diagnosis(CABTD)method plays a vital role in the early detection and diagnosis of breast tumors.However,a Brightness mode(B-mode)ultrasound image derives training feature samples that make closer isolation toward the infection part.Hence,it is expensive due to a metaheuristic search of features occupying the global region of interest(ROI)structures of input images.Thus,it may lead to the high computational complexity of the pre-trained DNN-based CABTD method.This paper proposes a novel ensemble pretrained DNN-based CABTD method using global-and local-ROI-structures of B-mode ultrasound images.It conveys the additional consideration of a local-ROI-structures for further enhan-cing the pretrained DNN-based CABTD method’s breast tumor diagnostic performance without degrading its visual quality.The features are extracted at various depths(18,50,and 101)from the global and local ROI structures and feed to support vector machine for better classification.From the experimental results,it has been observed that the combined local and global ROI structure of small depth residual network ResNet18(0.8 in%)has produced significant improve-ment in pixel ratio as compared to ResNet50(0.5 in%)and ResNet101(0.3 in%),respectively.Subsequently,the pretrained DNN-based CABTD methods have been tested by influencing local and global ROI structures to diagnose two specific breast tumors(Benign and Malignant)and improve the diagnostic accuracy(86%)compared to Dense Net,Alex Net,VGG Net,and Google Net.Moreover,it reduces the computational complexity due to the small depth residual network ResNet18,respectively.

50例卵巢恶性肿瘤B型超声诊断

本文分析50例卵巢恶性肿瘤的B型超声图象特点:肿块外形多不规则,包膜较厚不光滑,内部回声不均匀。约1/3病例出现腹水。超声物理性质:囊性占优势者5例,实质性13例,混合性32例。50例均与病检结果对照观察,物理性质符合率为90.0%,良、恶性符合率86.0%。

一种基于多核DSP的人体颈动脉超声成像算法的实现

超声成像在医学影像诊断中有着广泛的应用,传统的医学超声成像设备体积大、功耗高,便携性及网络传输性都有一定的限制。对常用的超声成像原理及算法进行分析及仿真,在超声成像前端、中端、后端3个处理阶段中,重点介绍中端处理方法,并将常用的人体组织及血流信息超声成像算法移植到在TMS320C6472多核DSP上,实现了人体颈动脉样本数据的成像。

超声成像在早期干燥综合征小鼠模型中的评价作用

目的探讨颌下腺超声成像在评价干燥综合征动物模型中的作用和价值。方法C57BL/6雌性小鼠建立SS模型,在d 0、21、28和35对小鼠进行唾液量、饮水量和体重等常规指标检测,d 35检测颌下腺指数和病理改变,同时运用Vevo 2100小动物超声成像系统,对小鼠颌下腺部位进行纵切超声检查,将超声观察的结果与常规检测指标进行相关性分析。结果SS小鼠造模d 28出现唾液量明显减少,饮水量显著增多,造模d 35颌下腺指数明显增高,颌下腺发生SS的典型病理改变。超声扫描在造模d 21发现SS组颌下腺轴面面积较正常组明显增高,颌下腺血流信号在d 28和35较正常组明显增多。分析表明,超声观察的结果与常规检测指标具有显著相关性。结论颌下腺的超声成像可能为SS动物模型的评价提供早期线索和半定量指标,在评价SS模型病情变化以及治疗SS的药效学基础研究中具有重要价值。

Magnetic resonance cholangiopancreatography for the detection of pancreatic duct stones in patients with chronic pancreatitis

AIM:To assess the role of magnetic resonance cholangiopancreatography(MRCP) in detection of pancreatic duct stones(PDS) in patients with chronic pancreatitis(CP).METHODS:Clinical data of 78 CP patients who were treated at the First Affi liated Hospital of Xi'an Jiaotong University(China) between January 2004 and July 2008 were retrospectively analyzed.A predictive model of pancreatic duct stones was established through logistic regression and its effectiveness was verifi ed.Among these patients, MRCP was performed in 60 patients who served as a control group, while 44 patients with a higher predictive value than the entry threshold of the predictive model served as an experimental group.RESULTS:The positive rate of PDS in the 78 patients with CP was 19.2%(15/78).The predictive entry threshold of the predictive model was 5%(P < 0.05).The possibility of existence of PDS could be predicted according to the following 4 indexes:gastrointestinal symptoms, intermittent abdominal pain, diabetes mellitus(DM)/impaired glucose tolerance(IGT) and positive B-mode ultrasound results.The incidence of PDS in the experimental group was higher than that in the control group(P < 0.05).CONCLUSION:MRCP is strongly suggested for the detection of PDS in patients with gastrointestinal symptoms, intermittent abdominal pain, DM/IGT and positive B-mode ultrasound results.

Contrast-enhanced ultrasound imaging for intestinal lymphoma

BACKGROUND Intestinal lymphoma is a rare tumor.Contrast-enhanced ultrasound(CEUS)findings of intestinal lymphoma have not been reported previously,and the relationship between CEUS and clinicopathological features and prognostic factors is still unknown.AIM To describe the B-mode US and CEUS features of intestinal lymphoma and investigate the correlation of CEUS and histopathological features.METHODS This was a single-center retrospective study.Eighteen patients with histologically confirmed intestinal lymphoma underwent B-mode US and CEUS examinations between October 2016 and November 2019.We summarized the features of Bmode US and CUES imaging of intestinal lymphoma and compared the frequency of tumor necrosis in intestinal lymphomas with reference to different pathological subtypes(aggressive or indolent)and clinical stage(early or advanced).The time–intensity curve parameters of CEUS were also compared between patients with normal and elevated serum lactate dehydrogenase.RESULTS In B-mode imaging,four patterns were observed in intestinal lymphoma:Mass type(12/18,66.7%),infiltration type(1/18,5.6%),mesentery type(4/18,22.2%)and mixed type(1/18,5.6%).All cases were hypoechoic and no cystic areas were detected.On CEUS,most cases(17/18,94.4%)showed arterial hyperechoic enhancement.All cases showed arterial enhancement followed by venous wash out.A relatively high rate of tumor necrosis(11/18,61.1%)was observed in this study.Tumor necrosis on CEUS was more frequent in aggressive subtypes(10/13,76.9%)than in indolent subtypes(1/5,20.0%)(P=0.047).There were no correlations between tumor necrosis and lesion size and Ann Arbor stage.There was no significant difference in time–intensity curve parameters between normal and elevated lactate dehydrogenase groups.CONCLUSION B-mode US and CEUS findings of intestinal lymphoma are characteristic.We observed a high rate of tumor necrosis,which appeared more frequently in aggressive pathological subtypes of intestinal lymphoma.

Two case reports of bilateral adrenal myelolipomas

Primary adrenal myelolipoma is a rare, non-functioning adrenal benign tumor that is composed of mature adipose tissue and a variable amount of haemopoietic elements. Clinically, it is difficult to get diagnosed with adrenal myelolipoma because the patient usually doesn't have obvious symptoms and signs in early stage. In the present study, two cases of primary bilateral adrenal myelolipomas are reported. Clinical presentation, imaging diagnostic features, histopathological changes and surgical treatments of the two patients are discussed. Preoperative diagnostic imaging examinations(B-mode ultrasonography, computed tomography and magnetic resonance imaging sans) assisted getting a prediction diagnosis of bilateral adrenal myelolipomas. A two-stage surgery was used to successfully excise bilateral adrenal myelolipomas in the two patients. Conventional open adrenalectomy was applied to remove the adrenal myelolipomas greater than 6 cm, and laparoscopic adrenalectomy was performed to excise the adrenal tumors smaller than 6 cm. Bilateral adrenal myelolipomas of the two patients were finally confirmed by postoperative histopathological examinations. Understanding clinical, imaging diagnostic and histopathological features of bilateral adrenal myelolipomas will facilitate timely diagnosis and treatment of this condition. Surgical removal of bilateral adrenal myelolipomas is safe, curative and beneficial.The two-stage surgery appears to be the best treatment option for the patients with bilateral adrenal myelolipomas because it achieves optimal treatment effectiveness with minimized sequelae.

Ultrasonogram of hepatocellular carcinoma is associated with outcome after radiofrequency ablation

AIM: To investigate the association between B-mode ultrasound classification of small hepatocellular carcinoma (HCC) and outcome after radiofrequency ablation (RFA).

Relationship between Dual-Energy X-Ray Absorptiometry-Derived Appendicular Lean Tissue Mass and Total Body Skeletal Muscle Mass Estimated by Ultrasound

Dual-energy X-ray absorptiometry (DXA) is an attractive method for evaluating sarcopenia, age-related loss of skeletal muscle mass and function, using appendicular lean tissue (aLT) mass for criteria of diagnosis, although minimal radiation is exposed. Skeletal muscle (SM) mass can be estimated by using ultrasound-measured muscle thickness (MTH). However, the association between these two methods is unclear. To examine the relationship between DXA-derived aLT mass and total body SM mass estimated by ultrasound, thirty-six healthy adults (18 men and 18 women) aged 19 - 65 years participated in this study. Ultrasound-measured muscle thickness was used to estimate the total SM mass. DXA was used to estimate whole body and regional body composition, and aLT mass was considered equivalent to the sum of lean tissue in both the right and left arms and legs. Total SM mass (26.3 ± 4.4 kg for men and 15.7 ± 2.6 kg for women) estimated by ultrasound was similar to DXA-estimated aLT mass (24.5 ± 3.8 kg for men and 15.7 ± 2.7 kg for women). There was a strong correlation between DXA-measured aLT mass and total SM mass estimated by ultrasound in men (r = 0.927, n = 18) and women (r = 0.931, n = 18) as well as overall sample (r = 0.975, n = 36). The ratio of total SM mass to aLT mass was 1.07 for men and 1.00 for women. These results suggest that DXA-derived aLT mass can be accurately predicted from ultrasound estimated total SM mass, although the predicted value may underestimate in men (approximately 7% at the group level).

Light and sound- emerging imaging techniques for inflammatory bowel disease

Patients with inflammatory bowel disease are known to have a high demand of recurrent evaluation for therapy and disease activity. Further, the risk of developing cancer during the disease progression is increasing from year to year. New, mostly non-radiant, quick to perform and quantitative methods are challenging, conventional endoscopy with biopsy as gold standard. Especially, new physical imaging approaches utilizing light and sound waves have facilitated the development of advanced functional and molecular modalities. Besides these advantages they hold the promise to predict personalized therapeutic responses and to spare frequent invasive procedures. Within this article we highlight their potential for initial diagnosis, assessment of disease activity and surveillance of cancer development in established techniques and recent advances such as wide-view full-spectrum endoscopy, chromoendoscopy, autofluorescence endoscopy, endocytoscopy, confocal laser endoscopy, multiphoton endoscopy, molecular imaging endoscopy, B-mode and Doppler ultrasound, contrast-enhanced ultrasound, ultrasound molecular imaging, and elastography.

Comparison of the Five Different Methods in Arterial Diameter Measurement

Background/Aims: In this study, the different types of arterial diameter measurement methods were com-pared with each other on rat model. Methods: The study was planned in three phases. In phase 1, all subjects (n = 30) underwent high resolution B-mode ultrasound examination and external diameter of the right com-mon carotid artery (RCCA) was measured. In phase 2, RCCA was explored. In phase 3, rats were put into three groups. Group 1 was kept at -20oC, group 2 was embedded in 4% formaldehyde solution. In group 3, circulatory system was filled with %20 latex solution. In all groups, digital image of the RCCA was taken after the processes mentioned above. Images were assessed by Image – Pro Plus software. Results: The greatest average diameter was observed in the high resolution B-mode ultrasound (phase 1). In group 1 and 2, direct measurement of the RCCA on living animal (phase 2) gave significantly wider diameter than those obtained at phase 3 in the same groups. Direct (phase 2) and latex (phase 3) measurements were equal in group 3. Conclusion: High resolution B-mode ultrasound gives larger, probably actual diameter of the artery. Latex injection results might correspond those encountered during operation.

Focal liver lesions found incidentally

Incidentally found focal liver lesions are a commonfinding and a reason for referral to hepatobiliary service.They are often discovered in patients with history of liver cirrhosis,colorectal cancer,incidentally during work up for abdominal pain or in a trauma setting.Specific points should considered during history taking such as risk factors of liver cirrhosis;hepatitis,alcohol consumption,substance exposure or use of oral con-traceptive pills and metabolic syndromes.Full blood count,liver function test and tumor markers can act as a guide to minimize the differential diagnosis and to categorize the degree of liver disease.Imaging should start with B-mode ultrasound.If available,contrast enhanced ultrasound is a feasible,safe,cost effective option and increases the ability to reach a diagnosis.Contrast enhanced computed tomography should be considered next.It is more accurate in diagnosis and better to study anatomy for possible operation.Contrast enhanced magnetic resonance is the gold standard with the highest sensitivity.If doubt still remains,the options are biopsy or surgical excision.

Study on shock wave-induced cavitation bubbles dissolution process

This study investigated dissolution processes of cavitation bubbles generated during in vivo shock wave（SW）-induced treatments. Both active cavitation detection（ACD） and the B-mode imaging technique were applied to measure the dissolution procedure of bi Spheres contrast agent bubbles by in vitro experiments. Besides, the simulation of SW-induced cavitation bubbles dissolution behaviors detected by the B-mode imaging system during in vivo SW treatments, including extracorporeal shock wave lithotripsy（ESWL） and extracorporeal shock wave therapy（ESWT）, were carried out based on calculating the integrated scattering cross-section of dissolving gas bubbles with employing gas bubble dissolution equations and Gaussian bubble size distribution. The results showed that（i） B-mode imaging technology is an effective tool to monitor the temporal evolution of cavitation bubbles dissolution procedures after the SW pulses ceased, which is important for evaluation and controlling the cavitation activity generated during subsequent SW treatments within a treatment period;（ii） the characteristics of the bubbles, such as the bubble size distribution and gas diffusion, can be estimated by simulating the experimental data properly.

Estimation of Sediment Incipient Velocity Using B-Mode Ultrasound Imaging Technique

Sediment incipient velocity （SIV） is a vital parameter for sediment research and river dynamics. This paper describes a novel method of estimating SIV based on the known flow velocity in the movable-bed model experiment. In this method, we use B-mode ultrasound imaging technique to get video images of moving particles and topography under water. By statistical analysis of video images, the relationship between the average number of imaging particles and flow velocity is obtained. The relationship between the change rate of average number and flow velocity is analyzed in sediment incipient process. These relationships are used to estimate the SIV. Lastly, the changed topography verifies the estimated velocity. The results show there is a sudden change in these relationships which can be used to estimate the SIV with high resolution by using a B-mode ultrasound device. The estimated SIV of plastic sands （particle size is about 0.25 mm） is 3.64 cm · s^-1 and the estimated SIV of natural sands （particle size is about 0.25 mm） is 5.47 cm · s^-1in the same condition.

Acoustic field distribution posterior to a tumor in B-Mode diagnostic ultrasonography

The image features, such as enhancements, shadows and lateral shadows, posterior to a tumor in a B-Mode diagnostic ultrasonography, are studied. The tumor is simplified as a homogeneous cylinder in an inhomogeneous medium. Using the ray theory we derive the intensity in the region behind the cylinder. Taking the influences of sound attenuation and the time gain compensation of the B-Mode displyer into acount , we simulate with a computer five images corresponding to our experiments conducted with a tissue equivalent phantom. The theoratical images seem to be in good qualitative agreement with the experimental results.

Cosmological parameter fittings with the BICEP2 data

Combining the latest Planck, Wilkinson Microwave Anisotropy Probe （WMAP）, and baryon acoustic oscillation （BAO） data, we exploit the recent cosmic microwave background （CMB） B-mode power spectra data released by the BICEP2 collaboration to constrain the cosmological parameters of the ACDM model, especially the primordial power spectra parameters of the scalar and the tensor modes, ns, as, r, nt. We obtain constraints on the parameters for a lensed ACDM model using the Markov Chain -- ＋0,0307 ＋0,0061 ＋0,0105 Monte Carlo （MCMC） technique, the marginalized 68% bounds are r -0.1043 -0.0914, ns -0.9617-0.0061, as =-0.0175-0.0097, nt = 0.5198＋-0.4579. We find that a blue tilt for nt is favored slightly, but it is still well consistent with flat or even red tilt. Our r value is slightly smaller than the one obtained by the BICEP group, in that we permit nt as a free parameter without imposing the single-field slow roll inflation consistency relation. When we impose this relation, then r= 0.2130-0.06096 ＋0.0446. For most other parameters, the best fit values and measurement errors are not altered significantly by the introduction of the BICEP2 data.