Objective:To evaluate the efficacy and safety of Wenxin Keli for premature beats in structurally normal heart systematically.Methods:Eight databases at home and abroad were searched to collect randomized controlled tr...Objective:To evaluate the efficacy and safety of Wenxin Keli for premature beats in structurally normal heart systematically.Methods:Eight databases at home and abroad were searched to collect randomized controlled trials of Wenxin Keli for premature beats without cardiac diseases.The included literatures were systematically evaluated with Cochrane Handbook 5.1 evaluation criteria and tools,and Meta analysis was performed with software RevMan5.3.Results:A total of 13 randomized controlled trials with 1278 subjects were included.The exprimental group used Wenxin Keli alone while the control group used antiarrhythmic medicine.The Meta analysis results showed that the total effective rate(RR=1.06,95%CI[0.97,1.16],P=0.23)and clinical symptom effective rate(RR=1.16,95%CI[0.94,1.44],P=0.18)of Wenxin Keli on idiopathic premature beats was not significantly different from western medicine group.The subgroup analysis of total effective rate showed that Wenxin Keli had no significant difference with metoprolol(RR=1.04,95%CI[0.95,1.15],P=0.41),bisoprolol(RR=1.32,95%CI[0.85,2.05],P=0.22)and propanone(RR=1.07,95%CI[0.90,1.26],P=0.44).ECG changes showed that the PR intervals(MD=-12.57,95%CI[-16.15,-8.99],P<0.00001)and QTc intervals(MD=-8.09,95%CI[-15.52,-0.65],P=0.03)in the western medicine group were prolonged significantly more than those of Wenxin Keli.In terms of safety,the incidence of adverse reactions of Wenxin Keli was significantly less than that of western medicine group(RR=0.32,95%CI[0.19,0.54],P<0.0001).Conclusion:The efficacy of Wenxin Keli in the treatment of premature beats with structurally normal heart is accurate,and there are no serious adverse reactions.However,because of the low quality of the included papers,which affected the reliability of the conclusions,high-quality clinical research is needed to further demonstrate.展开更多
We solve the relativistic Dirac equation for the shutter problem. We prove that, at intermediate relativistic energies, the probability density oscillates in time in a similar way to the optical Fresnel oscillations i...We solve the relativistic Dirac equation for the shutter problem. We prove that, at intermediate relativistic energies, the probability density oscillates in time in a similar way to the optical Fresnel oscillations in a straight edge. However, for extreme-relativistic beams, the Fresnel oscillations turn into quantum damped beats.展开更多
Objective:To explore the clinical efficacy of Ningxin Tongluo Decoction(宁心通络汤)combined with Dapagliflozin in the treatment of type 2 diabetes mellitus complicated with ventricular premature beats.Methods:Ninety-t...Objective:To explore the clinical efficacy of Ningxin Tongluo Decoction(宁心通络汤)combined with Dapagliflozin in the treatment of type 2 diabetes mellitus complicated with ventricular premature beats.Methods:Ninety-two patients with type 2 diabetes mellitus complicated with ventricular premature beats in our hospital were randomly divided into control group(n=46)and observation group(n=46).The control group was treated with routine Western medicine,and the observation group was treated with Ningxin Tongluo Decoction on the basis of the control group.The clinical efficacy of the two groups before and after treatment,TCM syndrome score,blood glucose levels[fasting blood glucose(GLU),glycosylated hemoglobin(Hb A1c)],glucose metabolism levels[fasting insulin(FINS),insulin resistance index(HOMA-IR)],the number of ventricular premature beats detected by 24-hour ambulatory electrocardiogram,heart rate turbulence(HRT)[initial oscillation(TO),oscillation slope(TS)],and heart rate variability(HRV)standard deviation of two normal R-R intervals(SDNN),standard deviation of average normal R-R intervals every 5 minutes(SDANN)and root mean square of adjacent normal R-R intervals(RMSSD)were observed.Results:After treatment,the total effective rate of the observation group was 89.13%,significantly higher than that of the control group(73.91%),and the difference was statistically significant(P<0.05).Both groups could reduce TCM syndrome score,blood glucose level,glucose metabolism level,reduce the number of ventricular premature beats,improve HRT and HRV levels,and the observation group was superior to the control group,and the difference was statistically significant(P<0.05).Conclusion:Ningxin Tongluo Decoction combined with Dapagliflozin is effective in treating type 2 diabetes mellitus patients with ventricular premature beats.It can reduce blood glucose level,improve HRV and HRT,improve autonomic nerve function and exert antiarrhythmic effect.展开更多
We study the colour-locked twin-noisy-field correlation effects in the fifth-order nonlinear susceptibility of ultrafast polarization beats in a cascade four-level system. More importantly, the fifth-order phase-sensi...We study the colour-locked twin-noisy-field correlation effects in the fifth-order nonlinear susceptibility of ultrafast polarization beats in a cascade four-level system. More importantly, the fifth-order phase-sensitive heterodyne detection of ultrafast polarization beats has been exploited. The fifth-order nonlinear optical response can be controlled and modified through the colour-locked correlation of twin noisy fields. Thus, this method with the phase dispersion information is a good way to measure the real and imaginary parts of the fifth-order nonlinear susceptibility.展开更多
Laser ranging with frequency comb intermode beats[IMBs]has been suffering from random phase drifts[RPDs]for two decades.In this study,we reveal the influence of signal transmission path on the RPDs and propose a real-...Laser ranging with frequency comb intermode beats[IMBs]has been suffering from random phase drifts[RPDs]for two decades.In this study,we reveal the influence of signal transmission path on the RPDs and propose a real-time suppression method using two IMBs of similar frequencies from different combs.As the two IMBs obtain similar RPDs during their transmission through same signal paths,the RPD of the original probing signal IMB is suppressed by deducting the RPD of the newly added local IMB in real time.In our experiments,a real-time suppression of RPDs is achieved using IMBs of 1001 and 1000 MHz.For the sampling time of 100 s,the effect of 19-fold suppression has been achieved.The proposed method provides a new solution for the long-standing phase drift problem in laser ranging with comb IMBs.展开更多
Electronic processes within atoms and molecules reside on the timescale of attoseconds. Recent advances in the laserbased pump-probe interrogation techniques have made possible the temporal resolution of ultrafast ele...Electronic processes within atoms and molecules reside on the timescale of attoseconds. Recent advances in the laserbased pump-probe interrogation techniques have made possible the temporal resolution of ultrafast electronic processes on the attosecond timescale, including photoionization and tunneling ionization. These interrogation techniques include the attosecond streak camera, the reconstruction of attosecond beating by interference of two-photon transitions, and the attoclock. While the former two are usually employed to study photoionization processes, the latter is typically used to investigate tunneling ionization. In this review, we briefly overview these timing techniques towards an attosecond temporal resolution of ionization processes in atoms and molecules under intense laser fields. In particular, we review the backpropagation method, which is a novel hybrid quantum-classical approach towards the full characterization of tunneling ionization dynamics. Continued advances in the interrogation techniques promise to pave the pathway towards the exploration of ever faster dynamical processes on an ever shorter timescale.展开更多
China and the Philippines agree to strengthen economic and trade cooperation while minimizing disputes Philippine President Benigno Aquino III recently completed a five-day visit to China, his first state visit to Chi...China and the Philippines agree to strengthen economic and trade cooperation while minimizing disputes Philippine President Benigno Aquino III recently completed a five-day visit to China, his first state visit to China since he took office last year.展开更多
Heart rate variability(HRV) analysis is affected by ectopic beats.An efficient method was proposed to deal with the ectopic beats.The method was based on trend correlation of the heart timing signal.Predictor of R-R i...Heart rate variability(HRV) analysis is affected by ectopic beats.An efficient method was proposed to deal with the ectopic beats.The method was based on trend correlation of the heart timing signal.Predictor of R-R interval(RRI) value at ectopic beat time was constructed by the weight calculation and the slope estimation of preceding normal RRI.The type of ectopic beat was detected and replaced by the predictor of RRI.The performance of the simulated signal after ectopic correction was tested by the standard value using power spectrum density(PSD) estimation,whereas the results of clinical data with ectopic beats were compared with the adjacent ectopic-free data.The result showed the frequency indexes after ectopy corrected had less error than other methods with the test of simulated signal and clinical data.It indicated our method could improve the PSD estimation in HRV analysis.The method had advantages of high accuracy and real time properties to recover the sinus node modulation.展开更多
基金National Natural Science Foundation of China(No.81774128)National key Research and development program(No.2019YFC1708404)。
文摘Objective:To evaluate the efficacy and safety of Wenxin Keli for premature beats in structurally normal heart systematically.Methods:Eight databases at home and abroad were searched to collect randomized controlled trials of Wenxin Keli for premature beats without cardiac diseases.The included literatures were systematically evaluated with Cochrane Handbook 5.1 evaluation criteria and tools,and Meta analysis was performed with software RevMan5.3.Results:A total of 13 randomized controlled trials with 1278 subjects were included.The exprimental group used Wenxin Keli alone while the control group used antiarrhythmic medicine.The Meta analysis results showed that the total effective rate(RR=1.06,95%CI[0.97,1.16],P=0.23)and clinical symptom effective rate(RR=1.16,95%CI[0.94,1.44],P=0.18)of Wenxin Keli on idiopathic premature beats was not significantly different from western medicine group.The subgroup analysis of total effective rate showed that Wenxin Keli had no significant difference with metoprolol(RR=1.04,95%CI[0.95,1.15],P=0.41),bisoprolol(RR=1.32,95%CI[0.85,2.05],P=0.22)and propanone(RR=1.07,95%CI[0.90,1.26],P=0.44).ECG changes showed that the PR intervals(MD=-12.57,95%CI[-16.15,-8.99],P<0.00001)and QTc intervals(MD=-8.09,95%CI[-15.52,-0.65],P=0.03)in the western medicine group were prolonged significantly more than those of Wenxin Keli.In terms of safety,the incidence of adverse reactions of Wenxin Keli was significantly less than that of western medicine group(RR=0.32,95%CI[0.19,0.54],P<0.0001).Conclusion:The efficacy of Wenxin Keli in the treatment of premature beats with structurally normal heart is accurate,and there are no serious adverse reactions.However,because of the low quality of the included papers,which affected the reliability of the conclusions,high-quality clinical research is needed to further demonstrate.
文摘We solve the relativistic Dirac equation for the shutter problem. We prove that, at intermediate relativistic energies, the probability density oscillates in time in a similar way to the optical Fresnel oscillations in a straight edge. However, for extreme-relativistic beams, the Fresnel oscillations turn into quantum damped beats.
文摘Objective:To explore the clinical efficacy of Ningxin Tongluo Decoction(宁心通络汤)combined with Dapagliflozin in the treatment of type 2 diabetes mellitus complicated with ventricular premature beats.Methods:Ninety-two patients with type 2 diabetes mellitus complicated with ventricular premature beats in our hospital were randomly divided into control group(n=46)and observation group(n=46).The control group was treated with routine Western medicine,and the observation group was treated with Ningxin Tongluo Decoction on the basis of the control group.The clinical efficacy of the two groups before and after treatment,TCM syndrome score,blood glucose levels[fasting blood glucose(GLU),glycosylated hemoglobin(Hb A1c)],glucose metabolism levels[fasting insulin(FINS),insulin resistance index(HOMA-IR)],the number of ventricular premature beats detected by 24-hour ambulatory electrocardiogram,heart rate turbulence(HRT)[initial oscillation(TO),oscillation slope(TS)],and heart rate variability(HRV)standard deviation of two normal R-R intervals(SDNN),standard deviation of average normal R-R intervals every 5 minutes(SDANN)and root mean square of adjacent normal R-R intervals(RMSSD)were observed.Results:After treatment,the total effective rate of the observation group was 89.13%,significantly higher than that of the control group(73.91%),and the difference was statistically significant(P<0.05).Both groups could reduce TCM syndrome score,blood glucose level,glucose metabolism level,reduce the number of ventricular premature beats,improve HRT and HRV levels,and the observation group was superior to the control group,and the difference was statistically significant(P<0.05).Conclusion:Ningxin Tongluo Decoction combined with Dapagliflozin is effective in treating type 2 diabetes mellitus patients with ventricular premature beats.It can reduce blood glucose level,improve HRV and HRT,improve autonomic nerve function and exert antiarrhythmic effect.
基金Project supported by the National Natural Science Foundation of China(Grant Nos60308002and60678005)the Foundation for the Author of National Excellent Doctoral Dissertation of China(Grant No200339)+2 种基金the Foundation for Key Program of Ministry of Education,China(Grant No105156)the Fok Ying-Tong Education Foundation for Young Teachers in the Higher Education Institutions of China(Grant No101061)the Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No20050698017)
文摘We study the colour-locked twin-noisy-field correlation effects in the fifth-order nonlinear susceptibility of ultrafast polarization beats in a cascade four-level system. More importantly, the fifth-order phase-sensitive heterodyne detection of ultrafast polarization beats has been exploited. The fifth-order nonlinear optical response can be controlled and modified through the colour-locked correlation of twin noisy fields. Thus, this method with the phase dispersion information is a good way to measure the real and imaginary parts of the fifth-order nonlinear susceptibility.
基金supported by the National Natural Science Foundation of China(NSFC)(Nos.52175501 and 51605120)the Heilongjiang Provincial Natural Science Foundation(No.LH2021E059)the National Key Research and Development Program of China(No.2020YFC2200204)。
文摘Laser ranging with frequency comb intermode beats[IMBs]has been suffering from random phase drifts[RPDs]for two decades.In this study,we reveal the influence of signal transmission path on the RPDs and propose a real-time suppression method using two IMBs of similar frequencies from different combs.As the two IMBs obtain similar RPDs during their transmission through same signal paths,the RPD of the original probing signal IMB is suppressed by deducting the RPD of the newly added local IMB in real time.In our experiments,a real-time suppression of RPDs is achieved using IMBs of 1001 and 1000 MHz.For the sampling time of 100 s,the effect of 19-fold suppression has been achieved.The proposed method provides a new solution for the long-standing phase drift problem in laser ranging with comb IMBs.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.92150105,11834004,12227807,and 12241407)the Science and Technology Commission of Shanghai Municipality (Grant No.21ZR1420100)。
文摘Electronic processes within atoms and molecules reside on the timescale of attoseconds. Recent advances in the laserbased pump-probe interrogation techniques have made possible the temporal resolution of ultrafast electronic processes on the attosecond timescale, including photoionization and tunneling ionization. These interrogation techniques include the attosecond streak camera, the reconstruction of attosecond beating by interference of two-photon transitions, and the attoclock. While the former two are usually employed to study photoionization processes, the latter is typically used to investigate tunneling ionization. In this review, we briefly overview these timing techniques towards an attosecond temporal resolution of ionization processes in atoms and molecules under intense laser fields. In particular, we review the backpropagation method, which is a novel hybrid quantum-classical approach towards the full characterization of tunneling ionization dynamics. Continued advances in the interrogation techniques promise to pave the pathway towards the exploration of ever faster dynamical processes on an ever shorter timescale.
文摘China and the Philippines agree to strengthen economic and trade cooperation while minimizing disputes Philippine President Benigno Aquino III recently completed a five-day visit to China, his first state visit to China since he took office last year.
文摘Bolt是一家总部设在美国波士顿的风投公司,专注早期创投项目,尤其是这两年火遍全球的智能硬件产品创业。这家公司的博客上最近发布了一篇由该公司的样件工程师（Prototype Engineer）Avery Louie所撰写的评测报告,他拆解了一副官方售价199美元的Beats Solo HD耳机,并根据自己的算法,很认真地同时也很冷静地分析并估算出了这副耳机的物料清单（BOM）成本,是惊人的16.892美元。然后,问题来了。原文经过摘译转载到中文世界,不意外地被叠加了某种“愤怒”情绪：价格200美元的Beats只值侣美元!售价居然可以是成本价的十几倍,这不是坑冤大头吗？知道Beats耳机烂,
基金Project supported by the Key Industrial Projects of Science of Zhejiang Province (No. 2007C21079)the National Key Technologies R&D Program (No. 2007BAI07A28) of China
文摘Heart rate variability(HRV) analysis is affected by ectopic beats.An efficient method was proposed to deal with the ectopic beats.The method was based on trend correlation of the heart timing signal.Predictor of R-R interval(RRI) value at ectopic beat time was constructed by the weight calculation and the slope estimation of preceding normal RRI.The type of ectopic beat was detected and replaced by the predictor of RRI.The performance of the simulated signal after ectopic correction was tested by the standard value using power spectrum density(PSD) estimation,whereas the results of clinical data with ectopic beats were compared with the adjacent ectopic-free data.The result showed the frequency indexes after ectopy corrected had less error than other methods with the test of simulated signal and clinical data.It indicated our method could improve the PSD estimation in HRV analysis.The method had advantages of high accuracy and real time properties to recover the sinus node modulation.
