Hox and ParaHox genes constitute two families of developmental regulators that pattern the Anterior-Posterior body axis in all bilaterians. The members of these two groups of genes are usually arranged in genomic clus...Hox and ParaHox genes constitute two families of developmental regulators that pattern the Anterior-Posterior body axis in all bilaterians. The members of these two groups of genes are usually arranged in genomic clusters and work in a coordinated fashion, both in space and in time. While the mechanistic aspects of their action are relatively well known, it is still unclear how these systems evolved. For instance, we still need a proper model of how the Hox and ParaHox clusters were assembled over time. This problem is due to the shortage of information on gene complements for many taxa （mainly basal metazoans） and the lack of a consensus phylogenetic model of animal relationships to which we can relate our new findings. Recently, several studies have shown that the Acoelomorpha most probably represent the first offshoot of the Bilateria. This finding has prompted us, and others, to study the Hox and ParaHox complements in these animals, as well as their activity during development. In this review, we analyze how the current knowledge of Hox and ParaHox genes in the Acoelomorpha is shaping our view of bilaterian evolution.展开更多
During the Late Neoproterozoic and Early Cambrian,a series of paleogeographic and paleoecological events occurred associated with deglaciations and the evolution of life.The appearance of fossils representing diverse ...During the Late Neoproterozoic and Early Cambrian,a series of paleogeographic and paleoecological events occurred associated with deglaciations and the evolution of life.The appearance of fossils representing diverse phyla,novel body plans and complex ecologies in Ediacaran and Cambrian sedimentary successions has sparked diverse hypotheses about potential drivers for the radiation of early animals during this interval.Recently,new macroscopic fossils of carbonaceous compressions with unique features have been found in Anning,Yunnan,China.The fossils’bodies are ribbon-shaped and bilaterally symmetric,with dense longitudinal features and transversal features.The fossils occur 0.68 m below a bentonite interlayer which has been dated 535.2±1.7 Ma by Ri-xiang Zhu and his team in 2009.The relatively simply morphology of these fossils,coupled with a lack of preserved internal structures challenge efforts taxonomically identify the precursor organism and definitively ally it to a living group.However,the symmetry and unusual features of the body are analogous to members of Platyzoa.The presence of ribbon-shaped fossils in the Zhongyicun Member in Anning indicates that these organisms were at least a locally significant component of Cambrian seafloor ecosystems,and may hold important implications for our understanding of the early evolution of Bilateria.展开更多
文摘Hox and ParaHox genes constitute two families of developmental regulators that pattern the Anterior-Posterior body axis in all bilaterians. The members of these two groups of genes are usually arranged in genomic clusters and work in a coordinated fashion, both in space and in time. While the mechanistic aspects of their action are relatively well known, it is still unclear how these systems evolved. For instance, we still need a proper model of how the Hox and ParaHox clusters were assembled over time. This problem is due to the shortage of information on gene complements for many taxa （mainly basal metazoans） and the lack of a consensus phylogenetic model of animal relationships to which we can relate our new findings. Recently, several studies have shown that the Acoelomorpha most probably represent the first offshoot of the Bilateria. This finding has prompted us, and others, to study the Hox and ParaHox complements in these animals, as well as their activity during development. In this review, we analyze how the current knowledge of Hox and ParaHox genes in the Acoelomorpha is shaping our view of bilaterian evolution.
基金The authors thank the China Geological Survey(DD20190008)the National Natural Science Foundation of China(41574024,41662003)programmes for supporting the project.
文摘During the Late Neoproterozoic and Early Cambrian,a series of paleogeographic and paleoecological events occurred associated with deglaciations and the evolution of life.The appearance of fossils representing diverse phyla,novel body plans and complex ecologies in Ediacaran and Cambrian sedimentary successions has sparked diverse hypotheses about potential drivers for the radiation of early animals during this interval.Recently,new macroscopic fossils of carbonaceous compressions with unique features have been found in Anning,Yunnan,China.The fossils’bodies are ribbon-shaped and bilaterally symmetric,with dense longitudinal features and transversal features.The fossils occur 0.68 m below a bentonite interlayer which has been dated 535.2±1.7 Ma by Ri-xiang Zhu and his team in 2009.The relatively simply morphology of these fossils,coupled with a lack of preserved internal structures challenge efforts taxonomically identify the precursor organism and definitively ally it to a living group.However,the symmetry and unusual features of the body are analogous to members of Platyzoa.The presence of ribbon-shaped fossils in the Zhongyicun Member in Anning indicates that these organisms were at least a locally significant component of Cambrian seafloor ecosystems,and may hold important implications for our understanding of the early evolution of Bilateria.
